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18篇 您的检索式:作者名="Erik Nelson"
    题名 作者 年代 出处 被引量
1IL-2 regulates Foxp3 expression in human CD4 + CD25 + regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo 显示文摘Emmanuel Zorn Erik A Nelson 2006Blood2006,108,:1
2Modeling multiple ecosystem services, biodiversity conservation, commodity production, and tradeoffs at landscape scales 显示文摘Erik Nelson Guillermo Mendoza James Regetz 2009Frontiers in Ecology and the Environment2009,7,1:1
3Behavior and failure of high-strength concrete subjected to biaxial-cyclic compression Loading显示文摘ERIK L Nelson RAMON L Carrasquillo 1988ACI Materials Journal1988,85,3:1
4An ionizable supramolecular dendrimer nanosystem for effective siRNA delivery with a favorable safety profile显示文摘Gene therapy using small interfering RNA(siRNA)is emerging as a novel therapeutic approach to treat various diseases.However,safe and efficient siRNA delivery still constitutes the major obstacle for clinical implementation of siRNA therapeutics.Here we report an ionizable supramolecular dendrimer vector,formed via self-assembly of a small amphiphilic dendrimer,as an effective siRNA delivery system with a favorable safety profile.By virtue of the ionizable tertiary amine terminals,the supramolecular dendrimer has a low positively charged surface potential and no notable cytotoxicity at physiological pH.Nonetheless,this ionizable feature imparted sufficient surface charge to the supramolecular dendrimer to enable formation of a stable complex with siRNA via electrostatic interactions.The resulting siRNA/dendrimer delivery system had a surface charge that was neither neutral,thus avoiding aggregation,nor too high,thus avoiding cytotoxicity,but was sufficient for favorable cellular uptake and endosomal release of the siRNA.When tested in different cancer cell lines and patient-derived cancer organoids,this dendrimer-mediated siRNA delivery system effectively silenced the oncogenes Myc and Akt2 with a potent antiproliferative effect,outperforming the gold standard vector,Lipofectamine 2000.Therefore,this ionizable supramolecular dendrimer represents a promising vector for siRNA delivery.The concept of supramolecular dendrimer nanovectors via self-assembly is new,yet easy to implement in practice,offering a new perspective for supramolecular chemistry in biomedical applications.Dinesh Dhumal Wenjun Lan Ling Ding Yifan Jiang Zhenbin Lyu Erik Laurini Domenico Marson Aura Tintaru Nelson Dusetti Suzanne Giorgio Juan Lucio Iovanna Sabrina Pricl Ling Peng 2021Nano Research2021,14,7:1
5Modeling the tradeoffs between ecosystem services and biodiversity 显示文摘Erik Nelson 2009Ecological Applications2009,7,1:1
6Steatosis Is an Independent Predictor of Relapse Following Rapid Virologic Response in Patients With HCV Genotype 3显示文摘Samir R. Shah Keyur Patel Patrick Marcellin Graham R. Foster Michael Manns Shyam Kottilil Letha Healey Erik Pulkstenis G. Mani Subramanian John G. McHutchison Mark S. Sulkowski Stefan Zeuzem David R. Nelson 2011Clinical Gastroenterology and Hepatology2011,,8:1
7The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression显示文摘Sharma Ankur Yeow Wen-Shuz Ertel Adam Coleman Ilsa Clegg Nigel Thangavel Chellappagounder Morrissey Colm Zhang Xiaotun Comstock Clay E S Witkiewicz Agnieszka K Gomella Leonard Knudsen Erik S Nelson Peter S Knudsen Karen E 2010Journal of Clinical Investigation2010,,12:1
8Using airborne laser scanning to monitor tree migrationin the boreal-alpine transition zone显示文摘Erik Naesset Ross Nelson 2007Remote Sensing of Environment2007,110,3:1
9Diabetes mellitus contribution to the remodeling of the tumor microenvironment in gastric cancer显示文摘Compelling pieces of evidence derived from both clinical and experimental research has demonstrated the crucial contribution of diabetes mellitus(DM)as a risk factor associated with increased cancer incidence and mortality in many human neoplasms,including gastric cancer(GC).DM is considered a systemic inflammatory disease and therefore,this inflammatory status may have profound effects on the tumor microenvironment(TME),particularly by driving many molecular mechanisms to generate a more aggressive TME.DM is an active driver in the modification of the behavior of many cell components of the TME as well as altering the mechanical properties of the extracellular matrix(ECM),leading to an increased ECM stiffening.Additionally,DM can alter many cellular signaling mechanisms and thus favoring tumor growth,invasion,and metastatic potential,as well as key elements in regulating cellular functions and cross-talks,such as the microRNAs network,the production,and cargo of exosomes,the metabolism of cell stroma and resistance to hypoxia.In the present review,we intend to highlight the mechanistic contributions of DM to the remodeling of TME in GC.Armando Rojas Cristian Lindner Iván Schneider Ileana Gonzàlez Hernan Araya Erik Morales Milibeth Gómez Nelson Urdaneta Paulina Araya Miguel Angel Morales 2021World Journal of Gastrointestinal Oncology2021,13,12:1
10Projecting global land-usechange and its effect on ecosystem service provision andbiodiversity with simple models显示文摘Erik Nelson Heather Sander 2010Plos One2010,12,14:1
11Lidar sampling for large-area forest characterization: A review显示文摘Michael A. Wulder Joanne C. White Ross F. Nelson Erik N?sset Hans Ole ?rka Nicholas C. Coops Thomas Hilker Christopher W. Bater Terje Gobakken 2012Remote Sensing of Environment2012,,:1
12Efficiency of incentives tojointly increase carbon sequestration and species conserva-tion on a landscape显示文摘Erik Nelson Stephen Polasky 2008PNAS2008,105,:1
13Environmental, economic, and energetic costs and benefits of biodiesel and ethanol biofuels显示文摘Jason Hill Erik Nelson David Tilman 2006Proceedings of the National Academy of Sciences of the United States of America2006,103,11:1
14Using airborne laser scanning to monitor tree migration in the boreal - alpine transition zone显示文摘Erik Nzesset Ross Nelson 2007Remote Sensing of Environment2007,110,:1
15The impact of land-use change on ecosystem services,biodiversity and returns to landowners:A case study in the State of Minnesota显示文摘Stephen Polasky Erik Nelson Derric Pennington etc 2011Environmental and Resource Economics2011,,2:1
16On the Convergence Rate of an Inexact Proximal Point Algorithm for Quasiconvex Minimization on Hadamard Manifolds显示文摘In this paper,we present an analysis about the rate of convergence of an inexact proximal point algorithm to solve minimization problems for quasiconvex objective functions on Hadamard manifolds.We prove that under natural assumptions the sequence generated by the algorithm converges linearly or superlinearly to a critical point of the problem.Nancy Baygorrea Erik Alex Papa Quiroz Nelson Maculan 2017Journal of the Operations Research Society of China2017,5,4:0
17Inexact Proximal Point Methods for Quasiconvex Minimization on Hadamard Manifolds显示文摘In this paper we present two inexact proximal point algorithms to solve minimization problems for quasiconvex objective functions on Hadamard manifolds.We prove that under natural assumptions the sequence generated by the algorithms are well defined and converge to critical points of the problem.We also present an application of the method to demand theory in economy.Nancy Baygorrea Erik Alex Papa Quiroz Nelson Maculan 2016Journal of the Operations Research Society of China2016,4,4:0
18Fungal diversity notes 1277-1386:taxonomic and phylogenetic contributions to fungal taxa显示文摘This is the twelfth contribution to the Fungal Diversity Notes series on fungal taxonomy,based on materials collected from many countries which were examined and described using the methods of morphology,anatomy,and strain culture,combined with DNA sequence analyses.110 taxa are described and illustrated,including five new genera,92 new species,eight new combinations and other taxonomic contributions(one new sequenced species,one new host and three new records)which are accommodated in 40 families and 1 incertae sedis in Dothideomycetes.The new genera are Amyloceraceomyces,Catenuliconidia,Hansenopezia,Ionopezia and Magnopulchromyces.The new species are Amyloceraceomyces angustisporus,Amylocorticium ellipsosporum,Arthrinium sorghi,Catenuliconidia uniseptata,Clavulina sphaeropedunculata,Colletotrichum parthenocissicola,Coniothyrium triseptatum,Cortinarius indorusseus,C.paurigarhwalensis,C.sinensis,C.subsanguineus,C.xiaojinensis,Diaporthe pimpinel-lae,Dictyosporella guizhouensis,Diplodia torilicola,Fuscoporia marquesiana,F.semiarida,Hansenopezia decora,Helicoarcta-tus thailandicus,Hirsutella hongheensis,Humidicutis brunneovinacea,Lentaria gossypina,L.variabilis,Lycoperdon lahorense,L.pseudocurtisii,Magnopulchromyces scorpiophorus,Moelleriella gracilispora,Neodevriesia manglicola,Neodidymelliopsis salvia,N.urticae,Neoroussoella magnoliae,Neottiella gigaspora,Ophiosphaerella chiangraiensis,Phaeotremella yunnanensis,Podosphaera yulii,Rigidoporus juniperinus,Rhodofomitopsis pseudofeei,Russula benghalensis,Scleroramularia vermispora,Scytinopogon minisporus,Sporormurispora paulsenii,Thaxteriellopsis obliqus,Tomentella asiae-orientalis,T.atrobadia,T.atrocastanea,T.aureomarginata,T.brevis,T.brunneoflava,T.brunneogrisea,T.capitatocystidiata,T.changbaiensis,T.citri-nocystidiata,T.coffeae,T.conclusa,T.cystidiata,T.dimidiata,T.duplexa,T.efibulata,T.efibulis,T.farinosa,T.flavidobadia,T.fuscocrustosa,T.fuscofarinosa,T.fuscogranulosa,T.fuscopelliculosa,T.globospora,T.gloeocystidiata,T.griseocastanea,T.griseofusca,T.griseomarginata,T.inconspicua,T.incrustata,T.interrupta,T.liaoningensis,T.longiaculeifera,T.longiechinuli,T.megaspora,T.olivacea,T.olivaceobrunnea,T.pallidobrunnea,T.pallidomarginata,T.parvispora,T.pertenuis,T.qingyuanensis,T.segregata,T.separata,T.stipitata,T.storea,Trichoderma ceratophylletum,Tyromyces minutulus,Umbelopsis heterosporus and Xylolentia reniformis.The new combinations are Antrodiella descendena,Chloridium macrocladum,Hansenopezia retrocurvata,Rhodofomitopsis monomitica,Rh.oleracea,Fuscoporia licnoides,F.scruposa and Ionopezia gerardii.A new sequenced species(Graphis supracola),one new host(Aplosporella prunicola)and three new geographical records(Golovinomyces monardae,Paradictyoarthrinium diffractum and Prosthemium betulinum),are reported.Hai-Sheng Yuan Xu Lu Yu-Cheng Dai Kevin D.Hyde Yu-He Kan Ivana Kušan Shuang-Hui He Ning-Guo Liu V.Venkateswara Sarma Chang-Lin Zhao Bao-Kai Cui Nousheen Yousaf Guangyu Sun Shu-Yan Liu Fang Wu Chuan-Gen Lin Monika C.Dayarathne Tatiana Baptista Gibertoni Lucas B.Conceição Roberto Garibay-Orijel Margarita Villegas-Ríos Rodolfo Salas-Lizana Tie-Zheng Wei Jun-Zhi Qiu Ze-Fen Yu Rungtiwa Phookamsak Ming Zeng Soumitra Paloi Dan-Feng Bao Pranami DAbeywickrama De-Ping Wei Jing Yang Ishara S.Manawasinghe Dulanjalee Harishchandra Rashika S.Brahmanage Nimali Ide Silva Danushka S.Tennakoon Anuruddha Karunarathna Yusufjon Gafforov Dhandevi Pem Sheng-Nan Zhang AndréL.C.Mde Azevedo Santiago Jadson Diogo Pereira Bezerra Bálint Dima Krishnendu Acharya Julieta Alvarez-Manjarrez Ali H.Bahkali Vinod K.Bhatt Tor Erik Brandrud Timur S.Bulgakov E.Camporesi Ting Cao Yu-Xi Chen Yuan-Yuan Chen Bandarupalli Devadatha Abdallah M.Elgorban Long-Fei Fan Xing Du Liu Gao Camila Melo Gonçalves Luis F.P.Gusmão Naruemon Huanraluek Margita Jadan Ruvishika S.Jayawardena Abdul Nasir Khalid Ewald Langer Diogo X.Lima Nelson Correia de Lima-Júnior Carla Rejane Sousa de Lira Jian-Kui(Jack)Liu Shun Liu Saisamorn Lumyong Zong-Long Luo Neven Matočec M.Niranjan JoséRibamar Costa Oliveira-Filho Viktor Papp Eduardo Pérez-Pazos Alan J.L.Phillips Peng-Lei Qiu Yihua Ren Rafael F.Castañeda Ruiz Kamal C.Semwal Karl Soop Carlos A.Fde Souza Cristina Maria Souza-Motta Li-Hua Sun Meng-Le Xie Yi-Jian Yao Qi Zhao Li-Wei Zhou 2020Fungal Diversity2020,,5:0
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