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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020,28,3: | 516 |
| 2 | Tricept机械手静刚度解析建模方法显示文摘以Tricept机械手的3自由度球坐标型并联机构为例,提出含恰约束支链的球坐标型并联构型装备静刚度解析建模方法。该方法首先借助子结构综合思想将末端执行器位姿变形分解为无约束主动支链的拉压变形、恰约束支链的弯曲变形及其扭转变形3个部分,然后利用虚功原理和结构矩阵法建立各子结构系统的静柔度模型,最后借助线性叠加原理组集整机末端静柔度模型。在建模过程中,侧重研究恰约束支链弯曲剐度以及铰链刚度的建模方法。在此基础上,考察了Tricept机械手中3自由度并联机构静刚度在工作空间中的变化规律,并借助全局性能指标评价了主要构件柔度对整机柔度的贡献。 | 王友渔 黄田 CHETWYND D G HU S J | 2008 | 机械工程学报2008,44,8: | 24 |
| 3 | Yes相关蛋白通过肿瘤坏死因子受体相关因子6控制内皮活化和血管炎症显示文摘继发于异常的内皮激活的微血管炎症和内皮功能障碍在败血症和器官衰竭的病理生理学中起关键作用。抑制内皮细胞过度活化的内在信号传导机制尚未完全明了。该研究旨在确定Yes相关蛋白(Yes-associated protein,YAP)(Hippo通路的主要转录共激活剂)在调节内皮活化和血管炎症的强度和程度中的中心作用。 | 刘青 叶鹏 Lv Y Kim K Sheng Y Cho J Qain Z Zhao YY Hu G Pan D Malik AB | 2018 | 中华高血压杂志2018,26,8: | 20 |
| 4 | 代谢健康的肥胖和腹型肥胖与高血压风险增加相关显示文摘代谢健康型肥胖是指具有正常代谢特征的肥胖人群。研究者在中国农村地区队列研究(the rural Chinese cohort study)的成年人中,探究了代谢健康型肥胖与高血压风险的关系。这项前瞻性队列研究纳入中国成人9137名,在基线时(2007-2008年)无高血压、2型糖尿病或血脂异常,在2013-2014年进行随访。 | 周卫(译) 袁源(审校) Zhao Y Qin P Sun HH Liu Y Liu D Zhou Q Guo C Li Q Tian G Wu X Hu D Sun X Zhang M | 2020 | 中华高血压杂志2020,28,9: | 7 |
| 5 | Characterization of the humoral and cellular immune responses against hepatitis C virus core induced by DNA-based immunization显示文摘 | Hu G J Wang R Y Han D S | 1999 | Vaccine1999,17,2324: | 2 |
| 6 | 地中海膳食干预研究中来自胆碱通路的血浆代谢物与心血管病风险的关系显示文摘血浆甜菜碱水平以及胆碱代谢水平与主要心血管病终点之间的联系仍不清楚。研究者评估了胆碱通路的代谢物与偶发心血管病风险以及地中海膳食干预的潜在调节效应之间的相关性。 | 黄洁 叶鹏 Guasch-Ferré M Hu FB Ruiz-Canela M Bulló M Toledo E Wang DD Corella D Gómez-Gracia E Fiol M Estruch R Lapetra J Fitó M Arós F Serra-Majem L Ros E Dennis C Liang L Clish CB Martínez-González MA Salas-Salvadó J | 2017 | 中华高血压杂志2017,25,12: | 2 |
| 7 | Terahertz Semiconductor Quantum Well Devices显示文摘For eventually providing terahertz science with compact and convenient devices,terahertz (1~10THz) quantum-well photodetectors and quantum-cascade lasers are investigated.The design and projected detector performance are presented together with experimental results for several test devices,all working at photon energies below and around optical phonons.Background limited infrared performance (BLIP) operations are observed for all samples (three in total),designed for different wavelengths.BLIP temperatures of 17,13,and 12K are achieved for peak detection frequencies of 9.7THz(31μm),5.4THz(56μm),and 3.2THz(93μm),respectively.A set of THz quantum-cascade lasers with identical device parameters except for doping concentration is studied.The δ-doping density for each period varies from 3.2×1010 to 4.8×1010cm-2.We observe that the lasing threshold current density increases monotonically with doping concentration.Moreover,the measurements for devices with different cavity lengths provide evidence that the free carrier absorption causes the waveguide loss also to increase monotonically.Interestingly the observed maximum lasing temperature is best at a doping density of 3.6×1010cm-2. | Liu H C Luo H Ban D Waichter M Song C Y Wasilewski Z R Buchanan M Aers G C SpringThorpe A J Cao J C Feng S L Williams B S Hu Q | 2006 | Journal of Semiconductors2006,27,4: | 2 |
| 8 | Study on the relationship between intake of trace elements and breast cancer mortality with chemometric methods显示文摘 | Zhai H L Chen X G Hu Z D | 2003 | Computational Biology and Chemistry2003,27,: | 2 |
| 9 | 生理性线粒体破碎是心脏适应能量需求增加的正常现象显示文摘线粒体在心脏中起着双重作用:负责满足能量需求和调节细胞凋亡。通常认为,线粒体的分裂和碎裂是病理性应激(如缺血)的结果,是线粒体质量差的指标,并导致线粒体自噬和细胞死亡。然而,最近的研究表明,抑制裂变也导致线粒体功能减弱和心脏损害,说明裂变对维持心脏和线粒体生物能量平衡十分重要。 | 刘莉 叶鹏 Coronado M Fajardo G Nguyen K Zhao M Kooiker KB Jung G Hu DQ Reddy S Sandoval E Stotland A Gottlieb RA Bernstein D | 2018 | 中华高血压杂志2018,26,1: | 2 |
| 10 | Some simple stability criteria of neutral delaydifferential systems 显示文摘 | Hu G D | 1996 | Applied Mathematics and Computation1996,80,: | 2 |
| 11 | Determination of hesperidin and naringin by micellar electrokinetic chromatography using a new recording mode显示文摘 | Zhao S G Chen X G Hu Z D | 2003 | Chromatographia2003,57,5: | 1 |
| 12 | Identification ofa gene expression profile that discriminates indirect - acting genotoxins from direct - acting genotoxins 显示文摘 | HU T GIBSON D P CARR G J | 2004 | Murat Res2004,549,: | 1 |
| 13 | Laser induced stabilization of the welding arc 显示文摘 | Hu B Ouden G D | 2005 | Science and Technology of Welding and Joining2005,10,1: | 1 |
| 14 | G protein-coupled re- ceptor 30 in tumor development 显示文摘 | Wang D Hu L Zhang G Zhang L | 2010 | Endocrine2010,38,1: | 1 |
| 15 | Identification of the optimal product configuration and parameters based on individual customer requirements on performance and costs in one - of - a - kind production 显示文摘 | HONG G HU L XUE D | 2008 | Interna- tional Journal of Production Research2008,46,12: | 1 |
| 16 | Environmental influences on bamboo Bashania fangiana growth and implications for giant panda conservation 显示文摘 | Reid D G Taylor A H Hu J C | 1991 | Journal of Applied Ecology1991,28,: | 1 |
| 17 | Transgenic rice with a synthetic crylAb gene from Bacillus thuringiensis is highly resistant to eight lepidopteran insects显示文摘 | Shu Q Y Ye G Y Cui H R Cheng X Xiang Y Wu D Gao M Xia Y Hu C Sardana R Altosaar I | 2000 | Mol Breed2000,,6: | 1 |
| 18 | 显示文摘 | McClung W G Clapper D L Hu S P | 2000 | Biomed Mater Res2000,49,3: | 1 |
| 19 | Retention of ginsenosides in dried ginseng root: Comparison of drying methods显示文摘 | Popovich D G Hu C Durance T D | 2005 | Journal of food science2005,70,6: | 1 |
| 20 | Antioxidant assessment of ananthocyanin-enriched blackberry extract 显示文摘 | Elisia I Hu C Popovich D G | 2007 | Food Chemistry2007,,101: | 1 |