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    题名 作者 年代 出处 被引量
12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway显示文摘当严重急性呼吸症候群日冕病毒(SARS-CoV ) 开始被认为与质膜通过直接熔化进入房间时,更最近的证据建议那个病毒条目可以也包含 endocytosis。我们发现了那 SARS-CoV 进入房间经由 pH 依赖并且受体依赖者 endocytosis。有任何一个 SARS-CoV 尖铁蛋白质或忍受尖铁的假病毒的房间的治疗导致了变换血管收缩素的酶的 translocation 2 (ACE2 ) , SARS-CoV 的功能的受体,从房间表面到内涵体。另外,忍受尖铁的假病毒和 1 在内涵体被发现到 colocalize 的早内涵体抗原。用象 caveolin-1 colocalization 学习一样的特定的 endocytic 小径禁止者和主导否定的 Eps15 的进一步的分析建议那个病毒条目被 clathrin 独立、 caveolae 独立的机制调停。而且,在质膜的微域,它被显示出到为许多生理的发信号小径作为平台扮演的充满胆固醇、 sphingolipid 富有的类脂化合物木排,被显示涉及病毒入口。SARS-CoV 的 Endocytic 入口可以扩展这里的 SARS-CoV 感染,和我们的调查结果的细胞的范围贡献 SARS-CoV 致病的理解,为抗病毒的药研究提供新信息。Wang,H Yang,P Liu,K Guo,F Zhang,Y Zhang,G Jiang,C 2008Cell Research2008,18,2:50
3The regulation of rotenone-induced inflammatory factor production by ATP-sensitive potassium channel expressed in BV-2 cells显示文摘Liu X Wu JY Zhou F Sun XL Yao HH Yang Y Ding JH Hu G 2006中国生物学文摘2006,20,10:11
4Sonohysterography: Principles, technique and role in diagnosis of endometrial pathology显示文摘Sonohysterography (SHG), which provides enhanced endometrial visualization during standard transvaginal ultrasonography, is a relatively safe procedure for the evaluation of endometrial pathology. It can be used to evaluate patients with abnormal vaginal bleeding or infertility. This modality offers real time imaging of the endometrium without exposure to ionizing radiation. SHG is typically used in patients for whom standard transvaginal ultrasonography does not show the endometrium well, show a potential abnormality for which further imaging is required, or in patients without endometrial pathology defined on routine transvaginal imaging but in whom there is a strong clinical suspicion of an abnormality. This article will discuss the utility of the sonohysterogram in evaluation of various endometrial pathologies. Imaging examples of these pathological entities will be illustrated as well.Thomas Yang Amit Pandya Leonardo Marcal Ronald O Bude Joel F Platt Deepak G Bedi Khaled M Elsayes 2013World Journal of Radiology2013,5,3:5
5Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats显示文摘Yang Y Liu X Long Y Wang F Ding JH Liu SY Sun YH Yao HH Wang H Wu J Hu G 2006中国生物学文摘2006,20,10:4
6Effects of iptakalim on extracellular glutamate and dopamine levels in the striatum of unilateral 6-hydroxydopamine-lesioned rats: a microdialysis study显示文摘Yang J Hu LF Liu X Zhou F Ding JH Hu G 2006中国生物学文摘2006,20,10:3
7“东风何时至,已绿湖上山”--远程卒中在中国显示文摘1背景介绍中国国家卒中登记数据显示,2007-2008年,中国急性缺血性卒中静脉溶栓率仅为1.6%。2011年中国的急性缺血性卒中患者发病至用药时间平均为180 min,入院至治疗时间平均为116 min,这些质量评估数据远逊于发达国家。目前,"互联网+医疗"在中国也受到了极大关注,中国卒中学会顺应时代成立了移动医疗分会,推动远程卒中在中国的发展。zhao g huang h yang f 张清华 2018中国卒中杂志2018,13,2:2
8全颗粒饲料对奶牛生产性能的影响显示文摘饲料中的中性洗涤纤维(NDF)含量和饲料颗粒直径是影响瘤胃功能的重要因素。试验评估了以颗粒饲料为主的奶牛瘤胃健康情况、NDF消化率和生产性能。选取8头荷斯坦母牛(336±30 d,体重346±35 kg),随机分配到交叉重复试验组中,奶牛安置于牛栏,自由采食。试验期为3周,前两周是适应期,最后一周为数据收集期。各组饲粮原料相同,但物理形式不同,分为全混合日粮(TMR)和颗粒料(直径=8 mm)。两组间物理有效NDF(pe NDF)不同,TMR组为39.8%,颗粒料组为11.8%。在试验过程中,干物质采食量(DMI)、饮水量、瘤胃反刍时间、瘤胃温度和pH情况均记录。3周后收集粪样,确定潜在的可消化NDF总消化率(pdNDF)。每阶段结束后计算平均日增重和饲料转化率。颗粒料组的DMI、DMI/体重和饮水量更高。而两组间平均日增重和饲料转化率无显著差异。颗粒料组的瘤胃反刍时间为241 min·d-1低于TMR组的507 min·d-1。饲料的不同物理外形对瘤胃温度、瘤胃pH无显著影响。TMR组的pdNDF总消化率为90.25%高于颗粒料组的86.82%。试验结果表明,动物易接受完整的颗粒饲料,DMI较高,且反刍时间减少,但瘤胃pH无显著变化。TMR组的pdNDF消化率显著增加。尽管两组奶牛在DMI和纤维消化方面表现不同,但总体表现相似,两组饲料的保存时间与其物理形式有关。在短期内,提供能满足NDF需求的完全颗粒饲料可改善瘤胃健康状况和动物生产性能,而较长时间的数据则需要进一步试验。Wang J Yang M Cao M Lin Y Che L Q Duraipandiyan V Al-Dhabi N A Fang Z F Xu S Y Feng B Liu G Wu D Bonfante E Palmonari A Mammi L Canestrari G Fustini M Formigoni A 2016饲料博览2016,0,12:2
9Mechanisms of fibrinolysis resistance and potential targets for thrombolysis in acute ischaemic stroke: lessons from retrieved stroke emboli显示文摘There has been growing interest and insight into the histological composition of retrieved stroke emboli.One of the main focuses of the stroke clot analysis literature has been the implications of clot composition on mechanical thrombectomy procedures.However,the holy grail of clot analysis may not be in the field of clot-device interaction,but rather,in understanding mechanisms of fibrinolysis resistance.The mechanisms underlying the low response to fibrinolytic therapy,even with the newer,more powerful agents,remain poorly understood.While factors such as embolus size,location and collateral status influence alteplase delivery and recanalisation rates;compositional analyses focused on histological and ultrastructural characteristics offer unique insights into mechanisms of alteplase resistance.In this review,we strive to provide comprehensive review of current knowledge on clot composition and ultrastructural analyses that help explain resistance to fibrinolysis.Waleed Brinjikji Oana Madalina Mereuta Daying Dai David F Kallmes Luis Savastano Yang Liu Shahid M Nimjee Raul G Nogueira Mehdi Abbasi Ramanathan Kadirvel 2021Stroke & Vascular Neurology2021,6,4:2
10Study on Determination of Iron, Cobalt, Nickel, Copper, Zinc and Manganese in Drinking Water by Solid-phase Extraction and RP-HPLC with 2-(2-Quinolinylazo)-5-Diethylaminophenol as Precolumn Derivatizing Reagent显示文摘Hu Q F Yang G Y Yang J H J Env0,,:2
11Determination of Copper, Nickel, Cobalt, Silver, Lead, Cadmium and Mercury Ions in Water by Solid Phase Extraction and the RP-HPLC with UV-Vis Detection显示文摘Hu Q F Yang G Y Zhao Y Y 2003Ana Bioanal Chem2003,375,78:2
12益生菌抑制自发性高血压大鼠的菌群失调和血压升高:短链脂肪酸的作用显示文摘该研究旨在评估益生菌短双歧杆菌CECT7263(BFM)及发酵乳酸杆菌CECT5716(LC40)、短链脂肪酸丁酸盐及醋酸盐对自发性高血压大鼠(spontaneously hypertensive rat,SHR)心血管的作用。方法和结果:5周龄的Wistar Kyoto大鼠(WKY)10只和周龄匹配的SHR 50只随机分为6组:对照WKY、对照SHR、BFM干预的SHR、LC40干预的SHR、丁酸盐干预的SHR和醋酸盐干预的SHR。袁源(译) 练桂丽(审校) Robles-Vera I Toral M de la Visitación N Sánchez M Gómez-Guzmán M Romero M Yang T Izquierdo-Garcia JL Jiménez R Ruiz-Cabello J Guerra-Hernández E Raizada MK Pérez-Vizcaíno F Duarte J 2020中华高血压杂志2020,28,9:2
13Butyltin accumulation in the marine clam Mya arenaria: An evaluation of its suitability for monitoring butyltin pollutin 显示文摘YANG R Q ZHOU Q F JIANG G B 2006Chemosphere2006,63,:1
14Dissipation of oxytetracycline in soils under different redox conditions显示文摘YANG J F YING G G ZHOU L J 2009Environl Poll2009,157,10:1
15Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease 显示文摘KATHARINA F STEPHAN G YANG Y F 2009BMC Neurosci2009,10,1:1
16Inverse application of charge simulation method in detecting faulty ceramic insulators and processing influence from tower 显示文摘HE W YANG F WANG J G 2006IEEE Transactions on Magnetics2006,42,4:1
17Multi-Walled Carbon Nanotube-Based Gas Sensors for NH3 Detection显示文摘Wang SG Qing Zhang Yang D J Sellin P J Zhong G F 2004Diamond and Related Materials2004,13,:1
18Chitosan nanoparticle as gene therapy vector via gastrointestinal mucosa administration显示文摘Zheng F Shi X W Yang G F 2007Life Sci2007,80,4:1
19Gas-liquid mass transfer behavior in three-phase CFB reactors 显示文摘Yang W G Wang J F Zhu L M 1999Chem Eng Sci1999,54,:1
20Photosynthetic use of exogenous inorganic carbon in the agarophyte Gracilaria lemaneifor- m/s 显示文摘ZOU D G XIA J R YANG Y F 2004Aquaculture2004,237,:1
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