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38篇 您的检索式:作者名="Geoffrey M S"
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1Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele 2009World Journal of Gastroenterology2009,15,10:20
2Coral decline threatens fish biodiversity in marine reserves显示文摘GEOFFREY P J MARK I M MAYA S 2004Proceedings of the National Academy of Sciences of the USA2004,101,:1
3Rhinoplasty for cleft and hemangioma-related nasal deformities显示文摘Thomas S Geoffrey Lee Schwartz M 2010Head and Neck Surgery2010,18,:1
4Selenium:an essential element for immune function显示文摘Roderick C M Teresa S R Geoffrey J B 1998Immunology today1998,19,8:1
5Simulation of gas-solid flows in riser using energy minimization multiscale model:effect of cluster diameter correlation显示文摘Milinkumar T S Ranjeet P U Moses O T Vishnu K P Geoffrey M E 0,,:1
6Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial显示文摘Stephen M Davis Geoffrey A Donnan Mark W Parsons Christopher Levi Kenneth S Butcher Andre Peeters P Alan Barber Christopher Bladin Deidre A De Silva Graham Byrnes Jonathan B Chalk John N Fink Thomas E Kimber David Schultz Peter J Hand Judith Frayne Graeme 2008Lancet Neurology2008,,4:1
7Concurrent resections of pancreatic islet cell cancers with synchronous hepatic metastases: Outcomes of an aggressive approach显示文摘Juan M Sarmiento Florencia G Que Clive S Grant Geoffrey B Thompson Michael B Farnell David M Nagorney 2002Surgery2002,,6:1
8Electroactive conducting polymers for corrosion control Part 2:Ferrous metals显示文摘Geoffrey M S Anton J D Gordon G W 2002Journal of Solid State Electrochemistry2002,6,:1
9Cyanobacterial toxins:Risk management for health protection显示文摘GEOFFREY A C LOUISE F M JAMES S M 2005Toxicology and Applied Pharmacology2005,203,3:1
10Challenges in microbial fuel cell development and operation 显示文摘KIM B H CHANG I S GEOFFREY M G 2007Appl Microbiol Biotechno2007,3,76:1
11Peltogynoids and homoisoflavonoids from Caesalpiniapulcherrima显示文摘David D M Geoffrey A C Djaja D S 1983Phytochemistry1983,22,:1
12Evaluation of L-ascorbic acid oxidation and SH concentration in soy-wheat composite dough显示文摘Geoffrey E M Nguyen S M 2004J Science of Food and Agriculture2004,,8:1
13Absence of early proinflammatory cytokine expression in experimental intracerebral hemorrhage显示文摘Adnan I Farreed M Geoffrey S 2001Neurosurgery2001,49,2:1
14Cyanobacterial toxins:Risk management for health protection显示文摘Geoffrey A C Louise F M James S M 2005Toxicology and Applied Pharmacology2005,203,3:1
15A mechanism for internal reflux in foam fractionation显示文摘Paul S Li X L Geoffrey M E 2008Biochem Eng2008,39,3:1
16Compara- tive study of silylation methods to improve the stability of silicate MCM-41 in aqueous solutions显示文摘Jenny M K Michelle L G Geoffrey W S 2003Chem Mater2003,15,3:1
17Evaluation of L-ascorbic acid oxidation and SH concentration in soy-wheat composite dough显示文摘GEOFFREY E M NGUYEN S M 2004J Science of Food and Agriculture2004,,8:1
18Serum vitamin D levels are lower in Australian children and adolescents with type 1 diabetes than in children without diabetes显示文摘Ristan M Greer Sharon L Portelli Betsy Shin‐Min Hung Geoffrey J Cleghorn Sarah K McMahon Jennifer A Batch Louise S Conwell 2012Pediatr Diabetes2012,,1:1
19A mechanism for internal reflux in foam fractionation 显示文摘Paul S Li X L Geoffrey M E 2008Biochem Eng2008,39,3:1
20Sulfur specification in heavy petroleums:In-formation from X-ray absorption near edge structure显示文摘Geoffrey S Waldo Rehert M K Carlson J Michael Mold- owan 1991Geochim Cosmochim Acta1991,55,3:1
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