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| 1 | Multiscale mobility networks and the spatial spreading of infectious diseases显示文摘 | Balcan D Colizza V Gon A B | 2009 | Proceedings of the NationalAcademy of Sciences2009，106，51： | 1 |
| 2 | The Camino intracranial pressure device in clin- ical practice 显示文摘 | Gelabert - Gon ~ alez M Ginesta - Galan V Sernamito Gar ~I a R | 2006 | Acta Neurochirurg2006，4，148： | 1 |
| 3 | Diamondoid and biomarker characterization of oils from the Llanos Orientales Basin, Colombia 显示文摘 | SPRINGER M V GARCIA D E GON(ALVES F T T | 2010 | Organic Geochemistry2010，41，9： | 1 |
| 4 | Stem cells associated with macroporous bioceramicsM for long bone repair:6 to 7 year outcome of a pilot clinical study显示文摘 | Mercacci M gon g Mouldachev V | 2007 | Tissue Eng2007，13，： | 1 |
| 5 | New insights into the nature of the active phase of VPO catalysts-aguantitative static LEIS study显示文摘 | Jansen W P A Ruitenbeele M Gon A W D V D | 2000 | J Catal2000，196，2： | 1 |
| 6 | PCR multiplex for detection of Salmonella Enteritidis, Typhi and Typhimurium and occurrence in poultry meat显示文摘 | Camila Guimar?es de Freitas ?ngela Patrícia Santana Patrícia Helena Caldeira da Silva Vítor Salvador Pic?o Gon?alves Márcia de Aguiar Ferreira Barros Fernando Araripe Gon?alves Torres Luci Sayori Murata Simone Perecmanis | 2010 | International Journal of Food Microbiology2010，，1： | 1 |
| 7 | Photochemical responses of three marine phytoplankton species exposed to ultraviolet radiation and increased temperature: Role of photoprotective mechanisms 显示文摘 | Halac S R Villafa?e V E Gon?alves R J | 2014 | Journal of Photochemistry Photobiology B: Biology2014，141，： | 1 |
| 8 | Distribution of fungi and aflatoxins in a stored peanut variety显示文摘 | nakai V K de Oliveira R L Gon~alez E | 2008 | Food Chemistry2008，106，1： | 1 |
| 9 | Water-tolerant zeolite catalyst for the acetalisation of glycerol显示文摘 | Silva C X A Gon?alves V L C Mota C J A | 2009 | Green Chemistry2009，11，： | 1 |
| 10 | Growth and characterization of monocrystalline tungsten substrates 显示文摘 | Ermolov S N Cortenraad R Semenov V N Denier van der Gon A W Bozhko S I Brongersma H H Glebovsky V G | 1999 | Vacuum1999，53，1： | 1 |
| 11 | Treatment of a pesticide-containing wastewater using combined biological and solar-driven AOPs at pilot scale显示文摘 | Francisca C. Moreira Vítor J.P. Vilar Ana C.C. Ferreira Felipe R.A. dos Santos Márcia Dezotti M.A. Sousa C. Gon?alves Rui A.R. Boaventura M.F. Alpendurada | 2012 | Chemical Engineering Journal2012，，： | 1 |
| 12 | Multiscale mobility networks and the spatial spreading of infectious diseases 显示文摘 | Balcan D Colizza V Gon alves B | 2009 | Proeeedings of the National Academy of Seienees2009，106，21： | 1 |
| 13 | What affects erosion resistance of refractory castables?显示文摘 | Santos V A A Gonlves L R G Gallo J | 2009 | Refractories Applications and News2009，14，6： | 1 |
| 14 | Social value and organizational performance in non-profit social organizations: Social entrepreneurship, leadership, and socioeconomic context effects显示文摘 | J. Augusto Felício Helena Martins Gon?alves Vítor da Concei??o Gon?alves | 2013 | Journal of Business Research2013，，10： | 1 |
| 15 | Soil dynamics and carbon stocks 10 years after restoration of degraded land using Atlantic forest tree species显示文摘 | Nogueira L J R J L de Moraes Gonalves Engel V L | 2011 | Forest Systems2011，20，3： | 1 |
| 16 | Mitochondrial distribution and adenosine triphosphate content of bovine oocytes before and after in vitro maturation:correlation with morphological criteria and developmental capacity after in vitro fertilization and culture显示文摘 | Stojkovic M Machado S A Stojkovic P Zakhartchenko V Hutzler P Gon(c)alves P B Wolf E | | 0，，： | 1 |
| 17 | Water- tolerant zeolite catalyst for the acetalisation of glycerol显示文摘 | SILVA C X A GON ALVES V L C MOTA C J A | 2009 | Green Chem2009，11，： | 1 |
| 18 | Glycerol acetals as anti-freezing additives for biodiesel显示文摘 | SILVA P H R GONALVES V L C MOTA C J A | 2010 | Bioresour Technol2010，101，15： | 1 |
| 19 | On the Nature of the FBS Blue Stellar Objects and the Completeness of the Bright Quasar Survey. II显示文摘 | A. M. Mickaelian A. C. Gon?alves M. P. Véron-Cetty P. Véron | 2001 | Astrophysics2001，，1： | 1 |
| 20 | A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions显示文摘The ability of endothelial cells to respond to blood flow is fundamental for the correct formation and maintenance of a functional and hierarchically organized vascular network.Defective flow responses,in particular related to high flow conditions,have been associated with atherosclerosis,stroke,arteriovenous malformations,and neurodegenerative diseases.Yet,the molecular mechanisms involved in high flow response are still poorly understood.Here,we described the development and validation of a 96-wells fluidic system,with interchangeable cell culture and fluidics,to perform high-throughput screenings under laminar high-flow conditions.We demonstrated that endothelial cells in our newly developed 96-wells fluidic system respond to fluid flow-induced shear stress by aligning along the flow direction and increasing the levels of KLF2 and KLF4.We further demonstrate that our 96-wells fluidic system allows for efficient gene knock-down compatible with automated liquid handling for high-throughput screening platforms.Overall,we propose that this modular 96-well fluidic system is an excellent platform to perform genome-wide and/or drug screenings to identify the molecular mechanisms involved in the responses of endothelial cells to high wall shear stress. | Catarina Gonçalves Fonseca Vânia Silvério David Barata Wolfgang Giese Holger Gerhardt Susana Cardoso Claudio Areias Franco | 2023 | Microsystems & Nanoengineering2023，9，5： | 0 |
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