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| 1 | Clinical characteristics of human infection with a novel avian-origin influenza A(H10N8) virus显示文摘 | Zhang Wei Wan Jianguo Qian Kejian Liu Xiaoqing Xiao Zuke Sun Jian Zeng Zhenguo Wang Qi Zhang Jinxiang Jiang Guanghui Nie Cheng Jiang Rong Ding Chengzhi Li Ran Horby Peter Gao Zhancheng | 2014 | Chinese Medical Journal2014，，18： | 12 |
| 2 | Magnetic properties and large magnetocaloric effects of GdPd intermetallic compound显示文摘With the intention to explore excellent magnetocaloric materials, the intermetallic compound GdPd was synthesized by arc melting and heat treatment. The microstructure, magnetic and magnetocaloric properties of the intermetallic compound of GdPd were investigated by X-ray diffraction(XRD), scanning electron microscopy(SEM) and the physical property measurement system(PPMS). A large reversible magnetocaloric effect is observed in GdPd accompanied by a second order magnetic phase transition from paramagnetism to ferromagnetism at ~39 K. The paramagnetic Curie temperature(θp) and the effective magnetic moment(μ_(eff))are determined to be 34.7 K and 8.12 μ_B/Gd,respectively. The maximum entropy change(|△S_M^(Max)|) and the relative cooling power(RCP) under a field change of 5 T are estimated to be 20.14 J/(kg·K) and 433 J/kg, respectively. The giant reversible magnetocaloric effects(both the large△S_M and the high RCP) together with the absence of thermal and field hysteresis make the GdPd compound an attractive candidate for low-temperature magnetic refrigeration. | Jianjun Huo Yusong Du Gang Cheng Xiaofei Wu Lei Ma Jiang Wang Zhengcai Xia Guanghui Rao | 2018 | Journal of Rare Earths2018，36，10： | 8 |
| 3 | Identification and fine mapping of quantitative trait loci for the number of vascular bundle in maize stem显示文摘Studies that investigated the genetic basis of source and sink related traits have been widely conducted.However, the vascular system that links source and sink received much less attention. When maize was domesticated from its wild ancestor, teosinte, the external morphology has changed dramatically; however, less is known for the internal anatomy changes. In this study, using a large maize-teosinte experimental population, we performed a high-resolution quantitative trait locus(QTL) mapping for the number of vascular bundle in the uppermost internode of maize stem.The results showed that vascular bundle number is dominated by a large number of small-effect QTLs, in which a total of 16 QTLs that jointly accounts for 52.2% of phenotypic variation were detected, with no single QTL explaining more than 6% of variation. Different from QTLs for typical domestication traits, QTLs for vascular bundle number might not be under directional selection following domestication.Using Near Isogenic Lines(NILs) developed from heterogeneous inbred family(HIF), we further validated the effect of one QTL qVb9-2 on chromosome 9 and fine mapped the QTL to a 1.8-Mb physical region. This study provides important insights for the genetic architecture of vascular bundle number in maize stem and sets basis for cloning of qVb9-2. | Cheng Huang Qiuyue Chen Guanghui Xu Dingyi Xu Jinge Tian Feng Tian | 2016 | Journal of Integrative Plant Biology2016，58，1： | 8 |
| 4 | Genome-wide Analysis of Transcriptional Variability in a Large Maize-Teosinte Population显示文摘基因表示规定在控制植物显型和改编起一个重要作用。这里,我们报导对通过 transcriptome 的基因表示变化的一个全面评价大 maize-teosinte 分析试验性的人口。染色体宽的印射识别了 25 ? 660 表示为 17 的量的特点 loci (eQTL )? 311 基因,捕获表示变化的一个崭新的范围。我们发现本地 eQTL 更经常被印射到邻近的基因,显示表示 piggybacking 的一个模式,它因而创造了共同调整的基因簇。在共同调整的基因簇以内的基因趋于有相关功能和分享的染色质修正。远 eQTL 与他们显著地在特定的功能的范畴充实的目标形成了 125 个重要远 eQTL 热点。由集成信息的不同来源,我们为许多新陈代谢的小径识别了通常认为的 trans- 管理者。我们证明 bHLH 抄写因素 R1 和 hexokinase HEX9 可能分别地为 flavonoid 生合成和 glycolysis 充当关键管理者。而且,我们证明驯服或改进显著地影响了全球基因表示,与选择指向的许多基因。特别兴趣,为生合成可能经历了的 benzoxazinoid 的 Bx 基因协调了在玉米和 teosinte 之间的 cis 规章的分叉,并且当玉米与一个不同草食动物社区传播了进适度的环境,使 Bx12 失去活性的 transposon 插入在强壮的选择下面。 | Xufeng Wang Qiuyue Chen Yaoyao Wu Zachary H. Lemmon Guanghui Xu Cheng Huang Yameng Liang Dingyi Xu Dan Li John F. Doebley Feng Tian | 2018 | Molecular Plant2018，11，3： | 7 |
| 5 | Archaeological records of Dadiwan in the past 60 ka and the origin of millet agriculture显示文摘This paper reports the recent excavation of Unit Dadiwan06 at the Dadiwan site in Qin’an County, Gansu.A 65 ka chronological framework is established for Dadiwan06 on the basis of absolute dating (AMS 14C and OSL), stratigraphy, climate change events and archaeology.Artifact distributions reveal patterns of human behavioral variation and adaptation over the past 60 ka, from primitive hunting and gathering to advanced hunting and gathering, to primitive Neolithic agriculture, and finally to advanced Neolithic agriculture. | ZHANG DongJu CHEN FaHu BETTINGER R L BARTON L JI DuXue MORGAN C WANG Hui CHENG XiaoZhong DONG GuangHui GUILDERSON T P ZHAO Hui | 2010 | Chinese Science Bulletin2010，55，16： | 6 |
| 6 | FGF1^(△HBS) prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression显示文摘As a classically known mitogen,fibroblast growth factor 1(FGF1)has been found to exert other pleiotropic functions such as metabolic regulation and myocardial protection.Here,we show that serum levels of FGF1 were decreased and positively correlated with fraction shortening in diabetic cardiomyopathy(DCM)patients,indicating that FGF1 is a potential therapeutic target for DCM.We found that treatment with a FGF1 variant(FGF1^(△HBS))with reduced proliferative potency prevented diabetes-induced cardiac injury and remodeling and restored cardiac function.RNA-Seq results obtained from the cardiac tissues of db/db mice showed significant increase in the expression levels of anti-oxidative genes and decrease of Nur77 by FGF1AHBS treatment.Both in vivo and in vitro studies indicate that FGF1^(△HBS) exerted these beneficial effects by markedly reducing mitochondrial fragmentation,reactive oxygen species(ROS)generation and cytochrome c leakage and enhancing mitochondrial respiration rate and β-oxidation in a 5;AMP-activated protein kinase(AMPK)/Nur77-dependent manner,all of which were not observed in the AMPK null mice.The favorable metabolic activity and reduced proliferative properties of FGF1^(△HBS) testify to its promising potential for use in the treatment of DCM and other metabolic disorders. | Dezhong Wang Yuan Yin Shuyi Wang Tianyang Zhao Fanghua Gong Yushuo Zhao Beibei Wang Yuli Huang Zizhao Cheng Guanghui Zhu Zengshou Wang Yang Wang Jun Ren Guang Liang Xiaokun Li Zhifeng Huang | 2021 | Signal Transduction and Targeted Therapy2021，6，4： | 6 |
| 7 | Pharmacokinetics and radiation dosimetry of ^(99m)Tc-3PRGD_2 in healthy individuals:A pilot study显示文摘99mTc-3PRGD2 is a new SPECT radiotracer for several tumor imaging with high uptake where integrinαvβ3 is highly expressed.This pilot study was to assess the safety,biodistribution and radiation dosimetry of 9,mTc-3PRGD2 in healthy volunteers.The 10 healthy male volunteers were injected with 99mTc-3PRGD2(786.7±55.8 MBq,19.1-24.2 mCi).Baseline measurements of vital signs,laboratory safety tests and 12-lead electrocardiogram were recorded before and after injection.Blood and urine samples were collected and radiation counts were obtained at various time points.Whole-body scans and ROIs of identified organs were used for visual analysis and estimating the radiation dosimetry.No adverse reactions were found during the study.99mTc-3PRGD2 exhibited a rapid clearance from the blood with less than 45%of the initial dosage at 10 min after injection and gradual increasing radioactivity in urine with(52.9±6)%of original dose at 1440 min.The whole-body imaging showed high radioactive accumulation in bladder.And the highest 99mTc-3PRGD2 uptake was found in the kidneys(3.50×10-2 mSv/MBq).The 99mTc-3PRGD2 exhibited good pharmacokinetic properties and little radiation burden.This study showed that 99mTc-3PRGD2 would be a safe and attractive SPECT agent in clinic applications. | CHENG Guanghui GAO Shi JI Tiefeng MA Qingjie JIA Bing CHEN Zuowei WANG Qing | 2012 | Nuclear Science and Techniques2012，23，6： | 5 |
| 8 | High performance of a unique mesoporous polystyrene-based adsorbent for blood purification显示文摘A multi-functional polystyrene based adsorbent(NKU-9)with a unique mesoporous and a high surface area was prepared by suspension polymerization for removal of therapeutic toxins in blood purification.The adsorbent produced had an almost equal amount of mesopore distribution in the range from 2 to 50 nm.The adsorption of serum toxins with different molecular weights were examined by in vitro adsorption assays and compared with some clinical currently used adsorbents such as HA-330,Cytosorb and BL-300 which are produced by China,America and Japan,respectively.Test results indicated that the adsorption rate for pentobarbital by NKU-9 was 81.24%which is nearly as high as HA-330(81.44%).The latter adsorbent is currently used for acute detoxification treatment in China.To reach adsorption equilibrium,NKU-9 was faster than HA-330,which implies short treatment time.For the removal of middle molecular toxins such as b2-microglobulin(98.88%),NKU-9 performed better adsorptive selectivity than Cytosorb(92.80%).In addition,NKU-9 showed high performance for the removal of albumin-bound toxins(e.g.,bilirubin),and its adsorption rate for total bilirubin(80.79%)in plasma was 8.4%higher than that of anion exchange resin BL-300 which is currently used to eliminate bilirubin in clinic.Therefore,our results indicate that the newly developed adsorbent with a wide distribution and almost equal amount of mesopores is a multifunctional adsorbent for high efficient removal of serum toxins with different molecular weights which might be an excellent blood purification adsorbent especially to treat diseases that conventional medical methods are low or not efficient. | Jian Chen Wenyan Han Jie Chen Wenhui Zong Weichao Wang Yue Wang Guanghui Cheng Chunran Li Lailiang Ou Yaoting Yu | 2017 | Regenerative Biomaterials2017，4，1： | 3 |
| 9 | Cloud-based data management system for automatic real-time data acquisition from large-scale laying-hen farms显示文摘Management of poultry farms in China mostly relies on manual labor.Since such a large amount of valuable data for the production process either are saved incomplete or saved only as paper documents,making it very difficult for data retrieve,processing and analysis.An integrated cloud-based data management system(CDMS)was proposed in this study,in which the asynchronous data transmission,distributed file system,and wireless network technology were used for information collection,management and sharing in large-scale egg production.The cloud-based platform can provide information technology infrastructures for different farms.The CDMS can also allocate the computing resources and storage space based on demand.A real-time data acquisition software was developed,which allowed farm management staff to submit reports through website or smartphone,enabled digitization of production data.The use of asynchronous transfer in the system can avoid potential data loss during the transmission between farms and the remote cloud data center.All the valid historical data of poultry farms can be stored to the remote cloud data center,and then eliminates the need for large server clusters on the farms.Users with proper identification can access the online data portal of the system through a browser or an APP from anywhere worldwide. | Chen Hongqian Hongwei Xin Teng Guanghui Meng Chaoying Du Xiaodong Mao Taotao Wang Cheng | 2016 | International Journal of Agricultural and Biological Engineering2016，9，4： | 3 |
| 10 | Glossy15 Plays an Important Role in the Divergence of the Vegetative Transition between Maize and Its Progenitor, Teosinte显示文摘 | Dingyi Xu Xufeng Wang Cheng Huang Guanghui Xu Yameng Liang Qiuyue Chen Chenglong Wang Dan Li Jinge Tian Lishuan Wu Yaoyao Wu Li Guo Xuehan Wang Weihao Wu Weiqiang Zhang Xiaohong Yang Feng Tian | 2017 | Molecular Plant2017，10，12： | 3 |
| 11 | Global ionospheric TEC response to a strong magnetic storm显示文摘The global characteristics of the ionospheric storm and irregularities as well as propagation of TEC (total electron content) disturbances during the strong mag-netic storm occurring in November 2004 were investigated by using the data of the IGS network. For the response of the global ionospheric TEC to this strong mag-netic storm, the following features are noticeable: 1) the maximum of the iono-spheric storm phase occurred around the main phase maximum of the magnetic storm; 2) the TEC response in equatorial and low latitudes was more remarkable than that in mid-high latitudes; 3) as a whole, the storm phase in the northern hemisphere was mainly positive, and it was negative in the southern hemisphere; 4) during the whole magnetic storm from November 7 to 11, the locations where the maxima of the positive and negative ionospheric storm phases occurred were nearly invariant to the Sun at low and equatorial latitudes, i.e. the 24-h recurrence. Analyzing results of TEC rate and its standard deviation showed that the iono-spheric irregularities and disturbances in the global mainly occurred around the main phase maximum of the storm, and they distributed in a large longitudinal re-gion for both day and night in mid-high latitudes and they generated and developed only after the sunset, and lasted out to the midnight in equatorial and low latitudes. The disturbance propagation parameters were also estimated by using the wavelet reconstruction and cross-correlation technologies for a set of spaced stations in the Northern America. | XU Liang CHENG GuangHui XU JiSheng LIU YongMin | 2008 | Science China(Technological Sciences)2008，51，10： | 2 |
| 12 | Broadband Acoustic Vibration Sensor Based on Cladding-Mode Resonance of Double-Cladding Fiber显示文摘We have proposed and demonstrated a double-cladding fiber (DCF) with cladding?mode resonance property for broadband acoustic vibration sensing. Since the fundamental mode in the core waveguide is able to be coupled to LP05 mode in the tube waveguide once the phase-matching condition is fulfilled, the transmission spectrum can exhibit a dip with a large extinction ratio. An acoustic vibration could induce the wavelength shift of such transmission spectrum, so that the intensity variation at a wavelength near the dip is coded with the information of the acoustic vibration signal. By demodulating the response of intensity variation, the frequency of the applied acoustic vibration signal can be recovered. Such a DCF-based sensor with an intensity modulation could measure the acoustic vibration with a broadband frequency range from 1 Hz to 400 kHz and exhibits the maximum signal-to-noise ratio (SNR) of ?80.79 dB when the vibration frequency is 20 kHz. The obtained results show that the proposed DCF-based acoustic vibration sensor has a potential application in environmental assessment, structural damage detection, and health monitoring. | Guanghui SUI Huanhuan LIU Fufei PANG Jiajing CHENG Tingyun WANG | 2019 | Photonic Sensors2019，9，3： | 2 |
| 13 | Low-efficiency-droop InGaN quantum dot light-emitting diodes operating in the “green gap”显示文摘Gallium nitride(Ga N)-based light-emitting diodes(LEDs)are important for lighting and display applications.In this paper,we demonstrate green-emission(512 nm)In Ga N quantum dot(QD)LEDs grown on a c-plane sapphire substrate by metal-organic chemical vapor deposition.A radiative lifetime of 707 ps for the uniform In Ga N self-assembled QDs is obtained by time-resolved photoluminescence measurement at 18 K.The screening of the built-in fields in the QDs effectively improves the performance of QD LEDs.These high quantum efficiency and high temperature stability green QD LEDs are able to operate with negligible efficiency droop and with current density up to 106 A∕cm^2.Our results show that In Ga N QDs may be a viable option as the active medium for stable LEDs. | CHUNYU ZHAO CHAK WAH TANG BILLY LAI GUANGHUI CHENG JIANNONG WANG KEI MAY LAU | 2020 | Photonics Research2020，8，5： | 2 |
| 14 | Modified SOR-type iterative method for Z-matrices显示文摘 | Huang Tingzhu Cheng Guanghui Cheng Xiaoyu | 2006 | Applied Mathematicsand Computation2006，，175： | 1 |
| 15 | Visible-light-enabled ruthenium-catalyzed para-C-H difluoroalkylation of anilides显示文摘Visible-light-mediated para-C-H difluoroalkylation of anilides via combination of steric effects and Lewis acid activation strategies has been developed. The addition of(C_6H_5O)_(2)P(O)OH and Ag_(2)CO_(3) properly tune the redox potential of ruthenium catalyst and leads to mild reaction conditions. The protocol exhibits broad functional group tolerance and allows the late-stage functionalization of complex bioactive molecules. | Yaohang Cheng Xian Zhang Guanghui An Guangming Li Zhenyu Yang | 2023 | Chinese Chemical Letters2023，34，3： | 1 |
| 16 | Modified SOR-type iterative method for Z-matrices 显示文摘 | Huang Tingzhu Cheng Guanghui Cheng Xiaoyu | 2006 | Applied Mathematics and Computation2006，，175： | 1 |
| 17 | Modified SOR-type iterative method for Z-matrices显示文摘 | HUNAG Tingzhu CHENG Guanghui CHENG Xiaoyu | 2006 | Ap- plied Mathematics and Computation2006，175，： | 1 |
| 18 | Umbilical cord mesenchymal stem cell transplantation significantly improves neurological function in patients with sequelae of traumatic brain injury显示文摘 | Sen Wang Hongbin Cheng Guanghui Dai Xiaodong Wang Rongrong Hua Xuebin Liu Peishen Wang Guangming Chen Wu Yue Yihua An | 2013 | Brain Research2013，，： | 1 |
| 19 | Summer rain pulse size and rainwater uptake by three dominant desert plants in a desertified grassland ecosystem in northwestern China显示文摘 | Xiaoli Cheng Shuqing An Bo Li Jiquan Chen Guanghui Lin Yuhong Liu Yiqi Luo Shirong Liu | 2006 | Plant Ecology2006，，1： | 1 |
| 20 | Phase relations of R-T-M temary system, crystal structure and magnetic properties of R(T,M)13 compounds (R = Light rare earth; T = Co, Fe; M = Al, Si) ( Ⅰ ) 显示文摘 | Liang Jingkui Rao Guanghui Tang Weihua Zhao Yanming Guo Yongquan Yan Xiaohua Zhang Yuling Cheng Xiangrong Xie Sishen Yu Yude Tian Jinghua Cheng Xiaolong Liang Jingmei | 1996 | Progress in Natural Science1996，6，6： | 1 |
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