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| 1 | Hepatitis E virus: Epidemiology, diagnosis, clinical manifestations, and treatment显示文摘The hepatitis E virus(HEV)is the fifth known form of viral hepatitis and was first recognized as the cause of an epidemic of unexplained acute hepatitis in the early 1980s.Globally,it is one of the most frequent causes of acute viral hepatitis.The majority of HEV infections are asymptomatic and lead to the spontaneous clearance of the virus.Among the eight different genotypes identified to date,HEV genotype 1(HEV1),HEV2,HEV3,and HEV4 are the most frequent genotypes causing infections in humans.HEV1 and HEV2 are prevalent in developing regions and able to result in large-scale outbreaks originating from contaminated water supplies.They are also responsible for severe hepatitis in pregnant patients and infants.In contrast,HEV3 and HEV4 are zoonotic,and the transmission of these genotypes to humans occurs mainly through the fecal contamination of water and consumption of contaminated meat from infected animals.Their main reservoir is the pig,and they are mostly encountered in developed countries.The major risk groups for HEV infection and its ensuing adverse consequences are pregnant women,infants,older people,immunocompromised individuals,patients with underlying chronic liver diseases,and workers that come into close contact with HEV-infected animals.In the clinical perspective,HEV infections have diverse clinical manifestations including acute and self-limiting hepatitis,acute-on-chronic liver disease,chronic hepatitis,cirrhosis,and liver failure.Although HEV mainly results in acute selflimiting infection,chronic HEV infection may occur among immunocompromised patients(e.g.,solid-organ transplant recipients).Additionally,HEV-associated extrahepatic manifestations involving various organs have been reported in the last decade,although the causal link for many of them still needs to be proven.Ribavirin and interferon-alpha are the most widely used agents for the treatment of HEV infections with a certain level of success.However,ribavirin is contraindicated in pregnant patients,and interferon-alpha cannot be used in most transplant recipients.Therefore,there is an urgent need for novel antiviral compounds that are safe and effective particularly for patients having contraindications for ribavirin or interferon-alpha and infected by the ribavirinresistant HEV.In this review article,a literature search using PubMed and MEDLINE databases was performed,up to March 2020.Only the articles published in English were reviewed. | Abdullah Tarık Aslan Hatice Yasemin Balaban | 2020 | World Journal of Gastroenterology2020，26，37： | 15 |
| 2 | The role of quantitative Ddimer levels in the follow-up and differential diagnosis of pulmonary thromboembolism and community-acquired pneumonia显示文摘 | Ayhan V Nurdan K Hatice K | 2012 | Turk J Med Sci2012，42，4： | 1 |
| 3 | Characteristic features of 20 patients with Sheehan's syndrome显示文摘 | Hatice SD Fatih K Serdal K | 2006 | Gvnecological Endocrinblogy2006，22，5： | 1 |
| 4 | The effects of regular aerobic exercise on renal functions in streptozotocin induced diabetic rats显示文摘 | Hatice K Sunay S Nilay E | 2010 | Journal of Sports Science and Medicine2010，9，： | 1 |
| 5 | Correlates of non-thyroidal ill-ness syndrome in chronic obstructive pulmonary disease显示文摘 | Fisun K Hatice O Aslihan B | | 0，，： | 1 |
| 6 | Changes in microbiological and chemical characteristics of an artisanal Turkish white cheese during ripening显示文摘 | ZUBEYDE O AYNUR G K HATICE A | 2006 | Swiss Society of Food Science and Technology2006，39，： | 1 |
| 7 | 3-T MRI of the biliary tract variations显示文摘 | Hakan ?nder Muhammed S?dd?k ?zdemir Güven Tekba? Faysal Ekici Hatice Gümü? Aslan Bilici | 2013 | Surgical and Radiologic Anatomy2013，，2： | 1 |
| 8 | Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic an- hydrase isozymes 显示文摘 | Rahmi K Metin B Hatice G | 2009 | Bioorg Med Chem2009，17，9： | 1 |
| 9 | Influence of fabric pattern on the abrasion resistance property of woven fabrics显示文摘 | HATICE K K MEHMETT | 2008 | Fibers and Textiles in Eastern Europe2008，16，1： | 1 |
| 10 | Ginkgo biloba( EGB761 ) affects apoptosis and nitric- oxide synthases in testicular torsion: An experimental study显示文摘 | Turgay A Ersagun K Hatice S | 2009 | Int Urol Nephrol2009，41，： | 1 |
| 11 | Influence of fabric pattern on the abrasion resistance property of woven fabrics显示文摘 | HATICE K K MEHMET T | 2008 | Fibers and Textiles in Eastern Europe2008，16，1： | 1 |
| 12 | Vortex formation in lid-driven arc-shape cavity flows at high Reynolds numbers显示文摘 | Hatice Mercan Kunt Atal?k | 2008 | European Journal of Mechanics / B Fluids2008，，1： | 1 |
| 13 | The effects of propofol infu- sion on hepatic and pancreatic function and acid base status in children undergoing craniotomy and receiving phenytoin显示文摘 | Hatice T Arzu M Ozge K | 2009 | Anesth Analg2009，109，36： | 1 |
| 14 | Magnetic resonance imaging of the condylar growth pattern and disk position after chin cup therapy:a preliminary study显示文摘 | Hatice G Gokmen K | 2005 | Angle Orthod2005，75，4： | 1 |
| 15 | Performance status of patients is the major prognostic factor at all stages of pancreatic cancer显示文摘 | Faruk Tas Fatma Sen Hatice Odabas Leyla K?l?c Serkan Kesk?n Ibrah?m Y?ld?z | 2013 | International Journal of Clinical Oncology2013，，5： | 1 |
| 16 | Imaging features of benign adrenal cysts显示文摘 | Hatice TS Murat K Duzgun Y | | 0，，： | 1 |
| 17 | Identification by culture, PCR, and immunohistochemistry of mycoplasmas and their molecular typing in sheep and lamb lungs with pneumonia in Eastern Turkey显示文摘 | Ay?e K?l?c Hakan Kalender Hatice Eroksuz Adile Muz Bülent Tasdemir | 2013 | Tropical Animal Health and Production2013，，7： | 1 |
| 18 | The effeets of regular aerobic exer- cise on renal fimctions in streptozotocin induced diabetic rats显示文摘 | HATICE K SUNAY S N1LAY E | 2010 | Journal of Sports Science and Medicine2010，，9： | 1 |
| 19 | A study on development of a scale to assess nursing students'performance in clinical settings显示文摘 | zgul K Hatice M Ayse B | 2008 | Journal of clinical nursing2008，18，： | 1 |
| 20 | Atypical EEG finding in subacute sclerosing panencephalitis 显示文摘 | Ozgul E Hatice K Ahmet G | 2005 | Clin Neurophysiol2005，29，3： | 1 |
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