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| 1 | A partition-ligation-combination-subdivision EM algorithm for haplotype inference with multiallelic markers: update of the SHEsis (http://gffzzfcd63c5b87fd4ae2h96xqxvcoxofk6cpq.ffgz.tsg.suse.edu.cn)显示文摘 | Zhiqiang Li Zhao Zhang Zangdong He Wei Tang Tao Li Zhen Zeng Lin He Yongyong Shi | 2009 | Cell Research2009，19，4： | 122 |
| 2 | Coordinated regulation of apical hook development by gibberellins and ethylene in etiolated Arabidopsis seedlings显示文摘当在土壤发芽时,当通过土壤耸出时,黑暗成年的 Arabidopsis 幼苗开发一个顶端的钩,它保护子叶和顶端的 meristematic 纸巾。几荷尔蒙被报导清楚地调制这个过程。以前的研究证明了乙烯和赤霉素(气体) 并列地调整钩发展,尽管内在的分子的机制大部分是未知的。当 paclobutrazol 镇压了时,这里,我们显示出提高的那 GA 3 ethylene-overexpression 和 EIN3-overexpression (EIN3ox ) 导致了钩弯曲,并且 della 异种展出了夸大的钩弯曲,它要求了发信号的未经触动的乙烯小径。基因学习表明那提高 GA 的钩开发依赖于无钩 1 (HLS1 ) ,调停的一个中央管理者多重发信号小径的输入在顶端的钩开发期间。我们进一步发现那 GA 3 导致(并且 DELLA 蛋白质镇压了) 在乙烯感觉迟钝的 3/EIN3-LIKE 的 HLS1 表示 1 (EIN3/EIL1 ) 依赖举止, EIN3/EIL1 由此激活 HLS1 抄写由对它的倡导者直接有约束力。另外, DELLA 蛋白质被发现与 EIN3/EIL1 的 DNA 有约束力的领域交往并且镇压 EIN3/EIL1-regulated HLS1 表示。有 naphthylphthalamic 酸的处理,一个极的植物生长素运输禁止者,镇压 EIN3ox 线的组成地夸大的钩弯曲和 della 异种,支持那植物生长素在钩开发乙烯和 GA 小径下游地工作。一起拿,我们的结果作为联系 DELLA 的抄写因素的一个新类识别 EIN3/EIL1 并且证明 GA 由经由 EIN3/EIL1 函数的 derepression 导致 HLS1 的表达式部分与乙烯在合作支持顶端的钩形成。 | Fengying An Xing Zhang Ziqiang Zhu Yusi Ji Wenrong He Zhiqiang Jiang Mingzhe Li Hongwei Guo | 2012 | Cell Research2012，22，5： | 34 |
| 3 | Deformation Behavior of Medium-strength TA18 High-pressure Tubes During NC Bending with Different Bending Radii显示文摘To improve the forming quality and forming limit of the numerical control (NC) bending of high-pressure titanium alloy tubes, in this study, using three-dimensional (3D) finite element method, deformation behavior of medium-strength TA18 high-pressure tubes during NC bending with different bending radii is investigated. The results show that the cross-sectional deformation and the wall thickness variation during NC bending of TA18 tubes using a small bending radius (less than 2 times of tube outside diameter) are clearly different from that using a normal bending radius (between 2 and 4 times of tube outside diameter). For bending with a normal bending radius, with or without a mandrel, the distribution of the flattening in the bending area resembles a platform and an asymmetric parabola, respectively. For bending with a small bending radius, with or without a mandrel, the flattening both distributes like a parabola, but the former has a stable peak which deflects toward the initial bending section, and the latter has a more pronounced peak with a bending angle and deflects slightly toward the bending section. The wall thickness variations with a normal bending radius, with and without a mandrel, both resemble a platform when the bending angle exceeds a certain angle. For the bending with a small radius, the distribution of the wall thickness variation without a mandrel follows an approximate parabola which increases in value as the bending angle increases. If a mandrel is used, the thickening ratio increases from the initial bending section to the bending section. | JIANG Zhiqiang ZHAN Mei YANG He XU Xudong LI Guangjun | 2011 | Chinese Journal of Aeronautics2011，24，5： | 16 |
| 4 | Numerically controlled bending performance of medium strength TA18 titanium alloy tubes under different die sets显示文摘The rapid development of aviation and aerospace technologies has led to increased interest in the application of numerically controlled(NC) technology for bending light-weight titanium alloy tubes.In order to study and develop advanced NC bending technology,it is necessary to understand the bending performance of medium strength TA18(Ti-3Al-2.5V,ASTM Gr.9) titanium alloy tubes during NC bending under different die sets.This paper focuses on the bending performance of medium strength TA18 tubes under different NC bending die sets,including the variations in the stress,strain,wall thickness,cross sectional deformation,and defects.The results show that adding a wiper die to the base die set decreases the radial,hoop,and tangential compressive stress and the tangential compressive strain,and adding a mandrel to the base die set also decreases these stresses,but increases the radial and hoop tensile stress and decreases the hoop compressive strain obviously,and brings about a three-dimensional tensile stress concentration where the mandrel provides support.For the NC bending of medium strength TA18 tubes,the flattening of cross section is more sensitive index than the thinning of wall thickness.Introducing a mandrel can improve the flattening of cross section obviously but it has a little worse effect on the thinning of wall thickness,and adding a wiper die to the base die set can inhibit the occurrence of the inside bulge but worsen the flattening of the cross section remarkably.Considering the above effects of the mandrel and wiper die on bending performance,it is reasonable to apply the die set comprising a bending die,clamp die,and pressure die for tubes with a small diameter and the die set including an appropriate mandrel additionally for tubes with a larger diameter,in order to bend the medium strength TA18 tubes with high quality and at low cost. | ZHAN Mei JIANG ZhiQiang YANG He XU XuDong LI GuangJun | 2011 | Science China(Technological Sciences)2011，54，4： | 13 |
| 5 | Simple PID Parameter Tuning Method Based on Outputs of the Closed Loop System显示文摘Most of the existing PID parameters tuning methods are only effective with pre-known accurate system models, which often require some strict identification experiments and thus infeasible for many complicated systems. Actually, in most practical engineering applications, it is desirable for the PID tuning scheme to be directly based on the input-output response of the closed-loop system. Thus, a new parameter tuning scheme for PID controllers without explicit mathematical model is developed in this paper. The paper begins with a new frequency domain properties analysis of the PID controller. After that, the definition of characteristic frequency for the PID controller is given in order to study the mathematical relationship between the PID parameters and the open-loop frequency properties of the controlled system. Then, the concepts of M-field and θ-field are introduced, which are then used to explain how the PID control parameters influence the closed-loop frequency-magnitude property and its time responses. Subsequently, the new PID parameter tuning scheme, i.e., a group of tuning rules, is proposed based on the preceding analysis. Finally, both simulations and experiments are conducted, and the results verify the feasibility and validity of the proposed methods. This research proposes a PID parameter tuning method based on outputs of the closed loop system. | HAN Jianda ZHU Zhiqiang JIANG Ziya HE Yuqing | 2016 | Chinese Journal of Mechanical Engineering2016，29，3： | 12 |
| 6 | Development of small/medium size no-till and minimum-till seeders in Asia:A review显示文摘The benefits of conservation agriculture(CA)have been widely recognized and CA has been widely adopted in many parts of the world.However,there are some factors that limit the widespread adoption of CA in Asia.The most prominent factor appears to be the lack of suitable CA seeders for small to medium sized land-holding(SLH)farmers.This paper summarizes the small to medium no-till and minimum-till seeders currently available in Asia,and classifies these seeders into four types:manually operated units,animal traction seeders,two-wheel tractor and four-wheel tractor driven seeders.Detailed characteristics have been provided for some typical CA seeders and comparisons were made as to their suitability under particular working conditions.Typically manual and animal traction seeders are confined to small farms and hilly areas,while the larger CA seeders suited to four-wheel tractors are used on larger acreages.To ensure seeding performance on most four-wheel tractor CA seeders,two types of anti-blocking mechanisms(passive and active anti-blocking)have been fitted.Finally,the paper proposes a future direction and development of CA seeders for small/medium size farms in Asia,and also suggests changes in policy support,improvement of anti-blocking mechanisms,suitability for various crops,geographical zones and the contribution of development by public private partnerships to advance the adoption of CA seeders. | He Jin Zhang Zhiqiang Li Hongwen Wang Qingjie | 2014 | International Journal of Agricultural and Biological Engineering2014，7，4： | 11 |
| 7 | Neddylation of PTEN regulates its nuclear import and promotes tumor development显示文摘PTEN tumor suppressor opposes the PI3K/Akt signaling pathway in the cytoplasm and maintains chromosomal integrity in the nucleus.Nucleus–cytoplasm shuttling of PTEN is regulated by ubiquitylation,SUMOylation and phosphorylation,and nuclear PTEN has been proposed to exhibit tumor-suppressive functions.Here we show that PTEN is conjugated by Nedd8 under high glucose conditions,which induces PTEN nuclear import without effects on PTEN stability.PTEN neddylation is promoted by the XIAP ligase and removed by the NEDP1 deneddylase.We identify Lys197 and Lys402 as major neddylation sites on PTEN.Neddylated PTEN accumulates predominantly in the nucleus and promotes rather than suppresses cell proliferation and metabolism.The nuclear neddylated PTEN dephosphorylates the fatty acid synthase(FASN)protein,inhibits the TRIM21-mediated ubiquitylation and degradation of FASN,and then promotes de novo fatty acid synthesis.In human breast cancer tissues,neddylated PTEN correlates with tumor progression and poor prognosis.Therefore,we demonstrate a previously unidentified pool of nuclear PTEN in the Nedd8-conjugated form and an unexpected tumor-promoting role of neddylated PTEN. | Ping Xie Zhiqiang Peng Yujiao Chen Hongchang Li Mengge Du Yawen Tan Xin Zhang Zhe Lu Chun-Ping Cui Cui Hua Liu Fuchu He Lingqiang Zhang | 2021 | Cell Research2021，31，3： | 11 |
| 8 | Cancer nanotechnology: Enhancing tumor cell response to chemotherapy for hepatocellular carcinoma therapy显示文摘Hepatocellular carcinoma(HCC)is one of the deadliest cancers due to its complexities,reoccurrence after surgical resection,metastasis and heterogeneity.In addition to sorafenib and lenvatinib for the treatment of HCC approved by FDA,various strategies including transarterial chemoembolization,radiotherapy,locoregional therapy and chemotherapy have been investigated in clinics.Recently,cancer nanotechnology has got great attention for the treatment of various cancers including HCC.Both passive and active targetings are progressing at a steady rate.Herein,we describe the lessons learned from pathogenesis of HCC and the understanding of targeted and non-targeted nanoparticles used for the delivery of small molecules,monoclonal antibodies,miRNAs and peptides.Exploring current efficacy is to enhance tumor cell response of chemotherapy.It highlights the opportunities and challenges faced by nanotechnologies in contemporary hepatocellular carcinoma therapy,where personalized medicine is increasingly becoming the mainstay.Overall objective of this review is to enhance our understanding in the design and development of nanotechnology for treatment of HCC. | Yongbing Sun Wen Ma Yuanyuan Yang Mengxue He Aimin Li Lei Bai Bin Yu Zhiqiang Yu | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，6： | 8 |
| 9 | Climate change and its effect on reference crop evapotranspiration in central and western Inner Mongolia during 1961-2009显示文摘水资源是到在中央、西方的内部蒙古的农业生产的主要限制之一,在的地方由干旱、半干旱的气候是特征的。参考庄稼土壤水分蒸发蒸腾损失总量(et 0 ) 是在农业生态系统的水周期的重要部分,它在庄稼生长和产量上有直接效果。et 0 上的气候变化的含意具有为关于安排的水管理和灌溉的农业的高重要性。这研究的目的是在时期上在在中央、西方的内部蒙古的 et 0 上在气候和它的效果分析变化 1961 ~ 2009。为这个目的,在越过学习区域的十个气象学的车站的数据被收集, FAO Penman-Monteith 56 方法被使用。结果证明平均温度,最大的温度和最小的温度由 0.49 莬增加了吗?? | Di HE Yaling LIU Zhihua PAN Pingli AN Liwei WANG Zhiqiang DONG Jingting ZHANG Xuebiao PAN Peiyi ZHAO | 2013 | Frontiers of Earth Science2013，7，4： | 8 |
| 10 | Actively priming autophagic cell death with novel transferrin receptor-targeted nanomedicine for synergistic chemotherapy against breast cancer显示文摘Recently, considerable attention in the field of cancer therapy has been focused on the mammalian rapamycin target(m TOR), inhibition of which could result in autophagic cell death(ACD). Though novel combination chemotherapy of autophagy inducers with chemotherapeutic agents is extensively investigated, nanomedicine-based combination therapy for ACD remains in infancy. In attempt to actively trigger ACD for synergistic chemotherapy, here we incorporated autophagy inducer rapamycin(RAP) into 7 pep-modified PEG-DSPE polymer micelles(7 pep-M-RAP) to specifically target and efficiently priming ACD of MCF-7 human breast cancer cells with high expression of transferrin receptor(Tf R). Cytotoxic paclitaxel(PTX)-loaded micelle(7 pep-M-PTX) was regarded as chemotherapeutic drug model. We discovered that with superior intracellular uptake in vitro and more tumor accumulation of micelles in vivo, 7 pep-M-RAP exhibited excellent autophagy induction and synergistic antitumor efficacy with 7 pep-M-PTX. Mechanism study further revealed that 7 pep-M-RAP and 7 pep-MPTX used in combination provided enhanced efficacy through induction of both apoptosis-and mitochondria-associated autophagic cell death. Together, our findings suggested that the targeted excess autophagy may provide a rational strategy to improve therapeutic outcome of breast cancer, and simultaneous induction of ACD and apoptosis may be a promising anticancer modality. | Dong Mei Binlong Chen Bing He Haibin Liu Zhiqiang Lin Jialiang Lin Xiaoyan Zhang Ning Sun Libo Zhao Xiaoling Wang Qiang Zhang | 2019 | Acta Pharmaceutica Sinica B2019，9，5： | 8 |
| 11 | Research progresses on Cherenkov and transit-time high-power microwave sources at NUDT显示文摘Research progresses on Cherenkov and transit-time high-power microwave(HPM)sources in National University of Defense Technology(NUDT)of China are presented.The research issues are focused on the following aspects.The pulse-shortening phenomenon in O-type Cerenkov HPM devices is suppressed.The compact coaxial relativistic backward-wave oscillators(RBWOs)at low bands are developed.The power efficiency in M-Type HPM tubes without guiding magnetic field increased.The power capacities and power efficiencies in the triaxial klystron amplifier(TKA)and relativistic transit-time oscillator(TTO)at higher frequencies increased.In experiments,some exciting results were obtained.The X-band source generated 2 GW microwave power with a pulse duration of 110 ns in 30 Hz repetition mode.Both L-and P-band compact RBWOs generated over 2 GW microwave power with a power efficiency of over 30%.There is approximately a 75% decline of the volume compared with that of conventional RBWO under the same power capacity conditions.A 1.755 GHz MILO produced 3.1 GW microwave power with power efficiency of 10.4%.A 9.37 GHz TKA produced the 240 MW microwave power with the gain of 34 dB.A 14.3 GHz TTO produced 1 GW microwave power with power efficiency of 20%. | Jiande Zhang Xingjun Ge Jun Zhang Juntao He Yuwei Fan Zhiqiang Li Zhenxing Jin Liang Gao Junpu Ling Zumin Qi | 2016 | Matter and Radiation at Extremes2016，1，3： | 7 |
| 12 | Unsaturated-sulfur-rich MoS2 nanosheets decorated on free-standing SWNT film: Synthesis, characterization and electrocatalytic application显示文摘此处,我们报导一条自底向上的 solvothermal 线路综合为氢进化反应的灵活、高度有效的瞬间 2@SWNT electrocatalyst (她的) 。描述表明包含 sulfurrich 地点的像分支的瞬间 2 nanosheets 在一致地在自立的围单人赛的碳 nanotube (SWNT ) 上驱散的 situ 电影,能暴露更不饱和的硫原子,与活跃地点允许优秀电的接触。展出的灵活催化剂优秀她有低过电位的表演(~ 在 10 妈 / 厘米 2) 和小 Tafel 斜坡(41 mV/dec ) 的 150 mV。为了推进,解释改进表演,本地电子结构被 X 光检查吸收调查近边的结构(XANES ) 分析,证明不饱和的硫原子并且在瞬间 2 和 SWNT 之间的强壮的电子联合的存在。这研究提供一条在原处合成的线路在催化剂微观结构,电子结构,和性质之中创造新多功能的灵活 hybridized 催化剂和有用卓见进关系。 | Daobin Liu Weiyu Xu Qin Liu Qun He Yasir A. Haleem Changda Wang Ting Xiang Chongwen Zou Wangsheng Chu Jun Zhong Zhiqiang Niu Li Song | 2016 | Nano Research2016，9，7： | 7 |
| 13 | Effects of key design parameters of tine furrow opener on soil seedbed properties显示文摘The structural parameters of tine furrow openers have significant effects on soil property of seed furrow in no-till planting,thereby affecting crop growth and yields.In order to analyze the effects of key parameters of tine furrow openers on soil properties(soil bulk density,soil water-stable aggregates(WSA),and soil disturbance)of the surface soil layer of 0-10 cm and surface straw disturbance,the tine furrow openers with different structural parameters,including cutting edge thickness,cutting edge curve,penetration clearance angle and rake angle,were designed and tested under no-till conditions.Orthogonal test and single factor test were performed to analyze the effects of different parameters.Results showed that the rake angle,cutting edge thickness and cutting edge curve had significant effects on cross-sectional area of furrow(Af)and disturbance of surface straw;the rake angle had a significant effect on soil bulk density.Soil types and operating depth had significant effects on soil disturbance caused by tine furrow openers.The concave type tine furrow opener produced the lowest soil disturbance and soil bulk density of seed furrow,the highest surface straw disturbance and the greatest content of WSA(>0.5 mm).With increasing rake angles of tine furrow opener,the width of seedbed(Wsb)and the Af decreased first and then increased,respectively,while the width of soil throw(Wst)and the height of ridge(Hr)increased.The Wsb and Af created by tine furrow opener with 60°rake angle were significantly lower than that with others,respectively.The tine furrow opener with rake angle ranged from 45°to 60°created the lowest soil bulk density.As the penetration clearance angle increased,the content of WSA(>0.5 mm)decreased,but the effect of penetration clearance angle on the content of WSA(<0.5 mm)was not significant.The cutting edge thickness(<2 mm)had no significant effects on soil properties of seedbed.This study could provide a reference for optimal design of the tine furrow opener to create more suitable seedbed environment,and promote the application of the light no-till planters. | Zhang Xiangcai Li Hongwen Du Ruicheng Ma Shaochun He Jin Wang Qingjie Chen Wanzhi Zheng Zhiqi Zhang Zhiqiang | 2016 | International Journal of Agricultural and Biological Engineering2016，9，3： | 7 |
| 14 | Cylindrical vector beam multiplexer/demultiplexer using off-axis polarization control显示文摘The emergence of cylindrical vector beam(CVB)multiplexing has opened new avenues for high-capacity optical communication.Although several configurations have been developed to couple/separate CVBs,the CVB multiplexer/demultiplexer remains elusive due to lack of effective off-axis polarization control technologies.Here we report a straightforward approach to realize off-axis polarization control for CVB multiplexing/demultiplexing based on a metal–dielectric–metal metasurface.We show that the left-and right-handed circularly polarized(LHCP/RHCP)components of CVBs are independently modulated via spin-to-orbit interactions by the properly designed metasurface,and then simultaneously multiplexed and demultiplexed due to the reversibility of light path and the conservation of vector mode.We also show that the proposed multiplexers/demultiplexers are broadband(from 1310 to 1625 nm)and compatible with wavelength-division-multiplexing.As a proof of concept,we successfully demonstrate a four-channel CVB multiplexing communication,combining wavelength-division-multiplexing and polarization-division-multiplexing with a transmission rate of 1.56 Tbit/s and a bit-error-rate of 10^(−6) at the receive power of−21.6 dBm.This study paves the way for CVB multiplexing/demultiplexing and may benefit high-capacity CVB communication. | Shuqing Chen Zhiqiang Xie Huapeng Ye Xinrou Wang Zhenghao Guo Yanliang He Ying Li Xiaocong Yuan Dianyuan Fan | 2021 | Light(Science & Applications)2021，10，12： | 6 |
| 15 | Historical records of polycyclic aromatic hydrocarbon deposition in a shallow eutrophic lake:Impacts of sources and sedimentological conditions显示文摘Sediment core samples collected from Lake Chaohu were analyzed for 15 priority polycyclic aromatic hydrocarbons(PAHs)to assess the spatial and temporal distributions of the PAHs during lacustrine sedimentary processes and regional economic development.Assessing the PAH sedimentary records over an approximately 100-year time span,we identified two stages in the PAH inputs and sources(before the 1970 s and after the 1970s)in the eastern lake region near a village,whereas three stages(before the 1950 s,1950s–1990s and after the1990s)were identified in the western lake region near urban and industrial areas.Rapid increases in the PAH depositional fluxes occurred during the second stage due to increased human activities in the Lake Chaohu basin.The composition and isomeric ratios of the PAHs revealed that pyrolysis is the main source of PAHs in this lake.Strong positive relationships between PAH concentration and the total organic carbon concentration,sediment grain size(< 4 μm),as well as the local population and Gross Domestic Product indicated that the sedimentary conditions impact the depositional characteristics of the PAHs;simultaneously,socioeconomic activities,such as energy consumption and the levels of urban industrialization and civilization,affect both the composition and abundance of the PAHs. | Chaocan Li Shouliang Huo Zhiqiang Yu Wei Guo Beidou Xi Zhuoshi He Xiangying Zeng Fengchang Wu | 2016 | Journal of Environmental Sciences2016，28，3： | 6 |
| 16 | Midterm results of diagnostic treatment and repair strategy in older patients presenting with nonrestrictive ventricular septal defect and severe pulmonary artery hypertension显示文摘 | Liu Aijun Li Zhiqiang Li Xiaofeng Fan Xiangming Su Junwu Zhang Jing He Yan Liu Yinglong | 2014 | Chinese Medical Journal2014，，5： | 6 |
| 17 | Unsymmetrical load effect of geologically inclined bedding strata on tunnels of passenger dedicated lines显示文摘In order to study the unsymmetrical load effect in geological bedding strata for the Muzhailing tunnel on the Lanzhou-Chongqing passenger dedicated line in China,we investigated the deformation,mechanical response and pressure of the surrounding rock and the mechanical characteristics of bolts of the tunnel.The results suggest that open zones appear at arch and invert where joints open up,when layered stratum is horizontal,or when the dip angle of inclined bedding is small.Open zones occur perpendicular to a joint.The failure mode is bending disjunction at the arch.What's more,with the dip angle increasing,tunnel excavating would induce shear zones where joints experience a certain shear displacement,and lead to obvious geological bedding unsymmetrical load.The failure mode is shear damage.For the joint dip angle in the range of 75-90°,the failure mode is flexural crushing at the wall and vertical shear rupture above the arch.The restraining effect of two sides weakens for vertical dip.On the whole,shear failure instability trend would occur and the tunnel collapses evenly.When the angle between the bolt and structure plane is greater than 23°,bolts can enhance the shearing stiffness of joint plane.Unfortunately,in the general purpose graph of tunnel for 250 km/h of passenger dedicated lines,the bolts have equal length and spacing.The rationale behind this is worthy of further study.For inclined bedding,the surrounding rock pressure at the left wall is more than that at the right wall.In addition,lining is likely to be damaged at left shoulder and side wall.With the dip angle increasing,the unsymmetrical load gradually achieves symmetry.Asymmetry design for support is recommended to reduce the unsymmetrical load on lining disturbed by excavation. | Benguo HE Zhiqiang ZHANG Yu CHEN | 2012 | Journal of Modern Transportation2012，20，1： | 6 |
| 18 | Genetic analysis and preimplantation genetic diagnosis of Chinese Marfan syndrome patients显示文摘Marfan syndrome (MFS)(OMIM 154700) is a relatively common autosomal dominant genetic disease that causes skeletal, ocular, and cardiovascular defects and was first described by a French pediatrician in 1896 (Bitterman and Sponseller, 2017). Its prevalence rate is 1/3000—1/5000, and more than 25% of cases are sporadic (Chiu et al., 2014). Studies have shown that about 90% of MFS is caused by variants in the fibrillin-1 gene (FBN1, OMIM 134797). FBN1, located on chromosome 15q21.1, encodes a macromolecular glycoprotein-fibrin 1, which aggregates to form microfibers in the extracellular matrix and distributes in various human connective tissues, such as periosteum, vessel wall, and crystal suspensor ligament. Variants in FNB1 have been reported in 65 exons, but the relationship between genotype and phenotype remains rather unclear (Sakai et al., 2016). Studies have also shown that patients with MFS and similar diseases may have variants in other related genes such as members of the transforming growth factor beta receptor (TGFBR) family (Mizuguchi et al., 2004;Sakai et al., 2006;Bolar et al., 2012;De Cario et al., 2018). For better prevention and treatment of MFS as well as for suspected MFS patients, there is a strong need for efficient genetic testing for early diagnosis and differential diagnoses of patients with related phenotypes (Aubart et al., 2018). | Meng Qin Xiaohui Zhu Zhe Zhang Xuemin Li Zhiqiang Yan Yuqian Wang Shuo Guan Yihua He Wenxin Zhang Liying Yan Jie Qiao Xu Zhi | 2019 | Journal of Genetics and Genomics2019，46，6： | 6 |
| 19 | Rapid Assessment on Potential Risks of Schistosomiasis Transmission—7 PLADs,China,2019 and 2021显示文摘Summary What is already known about this topic?Oncomelania hupensis(O.hupensis)and livestock are main infection sources of schistosomiasis.The schistosome infected O.hupensis and livestock’s feces are important risk factors in the transmission of schistosomiasis.What is added by this report?The potential risks of schistosomiasis transmission remain prevalent,giving an early warning to local government with information on existing transmission risks.It is expected that the effectiveness and efficiency of schistosomiasis surveillance could be improved by conducting rapid risk assessment at the beginning of transmission season. | Junyi He Hongqing Zhu Ziping Bao Lijuan Zhang Yinlong Li Ting Feng Suying Guo Wangping Deng Can Wang Hui Dang Tiewu Jia Chao Lyu Zhiqiang Qin Chunli Cao Jing Xu Shizhu Li Xiaonong Zhou | 2021 | China CDC weekly2021，3，51： | 5 |
| 20 | Improving Expectation Propagation with Lattice Reduction for Massive MIMO Detection显示文摘Efficient massive MIMO detection for practical deployment, which is with spatially correlated channel and high-order modulation, is a challenging topic for the fifth generation mobile communication(5 G). In this paper, we propose a lattice reduction aided expectation propagation(LRA-EP) algorithm for massive MIMO detection. LRA-EP applies expectation propagation in lattice reduced MIMO system to approach the distribution of lattice reduced constellation point by iterative refinement on its parameters(mean and covariance). The parameter refinement is based on the lattice reduced, well-conditioned MIMO channel. Numerical result shows that LRA-EP outperforms classic EP based MIMO detection(EPD) with 5~7 dB in terms of required signalto-noise ratio(SNR) for 1% packet error rate in spatially correlated channel for 256-QAM. We also show that LRA-EP has lower computation complexity than EPD. | Senjie Zhang Shi Jin Chao-Kai Wen Zhiqiang He | 2018 | China Communications2018，15，12： | 5 |
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