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| 1 | Spatial and Temporal Evolution of Surface Subsidence in Tianjin from 2015 to 2020 Based on SBAS-InSAR Technology显示文摘Tianjin is one of the inland cities with the most severe cases of subsidence hazard in China.The majority of the existing studies have mainly focused on Beijing-Tianjin-Hebei,and little attention has been given to Tianjin.In addition,these existing studies are short-term investigations,lacking long-term monitoring of surface subsidence.In the present study,we use the Small Baseline Subset Interferometric Synthetic Aperture Radar(SBAS-InSAR)technique to monitor the subsidence process in Tianjin between 2015 and 2020 and reveal its spatial and temporal variation.We divided the 44-view Sentinel-1A image data into three periods to avoid the effect of temporal and spatial decoherence by extracting the surface deformation field in Tianjin.We finally verified the accuracy and reliability of the inversion results using second-order leveling data.Results showed that the correlation coefficient r between the two reached 0.89,and the root mean square error was 4.84 mm/y.Obvious subsidence funnels exist in Tianjin,mainly in the towns of Wangqingtuo and Shengfang.These subsidence funnels have a subsidence deformation rate of-136.2 mm/y and a maximum cumulative settlement of-346.3 mm within the study period.The subsidence area tends to extend to the southwest.The analysis of annual rainfall,groundwater resource extraction,spatial location distribution of industrial areas combined with SBAS-InSAR inversion results indicates that overextraction of groundwater resources is the main cause of land subsidence in the area.Therefore,strict control of groundwater extraction is the main approach to mitigate land subsidence effectively. | Lyu ZHOU Yizhan ZHAO Zilin ZHU Chao REN Fei YANG Ling HUANG Xin LI | 2022 | Journal of Geodesy and Geoinformation Science2022，5，1： | 8 |
| 2 | Rapid Assessment on Potential Risks of Schistosomiasis Transmission—7 PLADs,China,2019 and 2021显示文摘Summary What is already known about this topic?Oncomelania hupensis(O.hupensis)and livestock are main infection sources of schistosomiasis.The schistosome infected O.hupensis and livestock’s feces are important risk factors in the transmission of schistosomiasis.What is added by this report?The potential risks of schistosomiasis transmission remain prevalent,giving an early warning to local government with information on existing transmission risks.It is expected that the effectiveness and efficiency of schistosomiasis surveillance could be improved by conducting rapid risk assessment at the beginning of transmission season. | Junyi He Hongqing Zhu Ziping Bao Lijuan Zhang Yinlong Li Ting Feng Suying Guo Wangping Deng Can Wang Hui Dang Tiewu Jia Chao Lyu Zhiqiang Qin Chunli Cao Jing Xu Shizhu Li Xiaonong Zhou | 2021 | China CDC weekly2021，3，51： | 5 |
| 3 | Diagnosis and treatment of Helicobacter pylori infections in children and elderly populations显示文摘Helicobacter pylori(H.pylori)infection is associated with various gastric and extra-gastric diseases.Importantly,this infection is the strongest known risk factor for gastric cancer(GC).H.pylori eradication can effectively prevent H.pylori infectionassociated diseases in H.pylori-positive patients,including children and elderly subjects.However,a limited selection of antibiotics,a higher reinfection rate,and certain spontaneous clearance rates,to some extent,restrict the choice of H.pylori treatments in pediatrics.In addition,it is imperative to perform an accurate diagnosis of H.pylori infection in children by determining the presence of the H.pylori infection and the underlying cause of symptoms.In elderly patients,poor tolerance to drugs and higher sensitivity to adverse effects are major concerns during H.pylori therapy.Recent studies have demonstrated that H.pylori eradication could significantly lower the GC risk in the elderly population.The benefit and risk of H.pylori eradication in elderly patients should be comprehensively considered and balanced.If available,susceptibility-based tailored therapies may be preferable in eradicating H.pylori.In addition,to increase the eradication rate and reduce adverse effects,new therapeutic strategies(e.g.,probiotic supplementation,berberine supplementation,dual therapy)for H.pylori infection are being extensively investigated.The impact of H.pylori eradication with antibiotics on the microbiota in children has been explored,but further high-quality studies are crucial to delineate the extent of H.pylori eradication affecting the microbial community in children.In this review,we summarize the current understanding of H.pylori diagnosis and treatment in children and the elderly population and aim to provide insights into the efficient management and treatment implementation in these populations. | Chao Peng Yi Hu Zhong-Ming Ge Quan-Ming Zou Nong-Hua Lyu | 2019 | Chronic Diseases and Translational Medicine2019，5，4： | 5 |
| 4 | Precise orbit determination for BDS satellites显示文摘Since the frst pair of BeiDou satellites was deployed in 2000,China has made continuous eforts to establish its own independent BeiDou Navigation Satellite System(BDS)to provide the regional radio determination satellite service as well as regional and global radio navigation satellite services,which rely on the high quality of orbit and clock products.This article summarizes the achievements in the precise orbit determination(POD)of BDS satellites in the past decade with the focus on observation and orbit dynamic models.First,the disclosed metadata of BDS satellites is presented and the contribution to BDS POD is addressed.The complete optical properties of the satellite bus as well as solar panels are derived based on the absorbed parameters as well the material properties.Secondly,the status and tracking capabilities of the L-band data from accessible ground networks are presented,while some low earth orbiter satellites with onboard BDS tracking capability are listed.The topological structure and measurement scheme of BDS Inter-Satellite-Link(ISL)data are described.After highlighting the progress on observation models as well as orbit perturbations for BDS,e.g.,phase center corrections,satellite attitude,and solar radiation pressure,diferent POD strategies used for BDS are summarized.In addition,the urgent requirement for error modeling of the ISL data is emphasized based on the analysis of the observation noises,and the incompatible characteristics of orbit and clock derived with L-band and ISL data are illuminated and discussed.The further researches on the improvement of phase center calibration and orbit dynamic models,the refnement of ISL observation models,and the potential contribution of BDS to the estimation of geodetic parameters based on L-band or ISL data are identifed.With this,it is promising that BDS can achieve better performance and provides vital contributions to the geodesy and navigation. | Qile Zhao Jing Guo Chen Wang Yifei Lyu Xiaolong Xu Chao Yang Junqiang Li | 2022 | Satellite Navigation2022，3，1： | 4 |
| 5 | GmCRY1s modulate gibberellin metabolism to regulate soybean shade avoidance in response to reduced blue light显示文摘Soybean is an important legume crop that displays the classic shade avoidance syndrome(SAS),including exaggerated stem elongation,which leads to lodging and yield reduction under density farming conditions.Here,we compared the effects of two shade signals,low red light to far-red light ratio(R:FR)and low blue light(LBL),on soybean status and revealed that LBL predominantly induces excessive stem elongation.We used CRISPR-Cas9-engineered Gmcry mutants to investigate the functions of seven cryptochromes(GmCRYs)in soybean and found that the four GmCRY1s overlap in mediating LBL-induced SAS.Lightactivated GmCRY1s increase the abundance of the bZlP transcription factors STF1 and STF2,which directly upregulate the expression of genes encoding GA2 oxidases to deactivate GA1 and repress stem elongation.Notably,GmCRY1b overexpression lines displayed multiple agronomic advantages over the wild-type control under both dense planting and intercropping conditions.Our study demonstrates the integration of GmCRY1-mediated signals with the GA metabolic pathway in the regulation of LBL-induced SAS in soybean.It also provides a promising option for breeding lodging-resistant,high-yield soybean cultivars in the future. | Xiangguang Lyu Qican Cheng Chao Qin Yinghui Li Xinying Xu Ronghuan Ji Ruolan Mu Hongyu Li Tao Zhao Jun Liu Yonggang Zhou Haiyan Li Guodong Yang Qingshan Chen Bin Liu | 2021 | Molecular Plant2021，14，2： | 4 |
| 6 | Evaluation of Xpert MTB/RIF for the Diagnosis of Extrapulmonary Tuberculosis in China显示文摘We evaluate the performance of Xpert MTB/RIF for the diagnosis of extrapulmonary tuberculosis(EPTB)in China.The performance of Xpert was evaluated compared to the composite reference standard(CRS),drug susceptibility testing(DST),and imaging examination.The overall sensitivity and specificity of Xpert were 64.1%(195/304)and 100%(24/24),respectively,using CRS as the gold standard.The sensitivity | YUAN Mei LYU Yan CHEN Su Ting CAi Chao LI Yuan ZHANG Zhi Guo LI Yun Xu DONG Ling Ling FU Yu Hong HUANG Hai Rong GAO Ji Min LI Wei Min | 2016 | Biomedical and Environmental Sciences2016，29，8： | 3 |
| 7 | 大麦ASYMMETRIC LEAVES2/LATERAL OR-GAN BOUNDARIES(AS2/LOB)基因家族的全基因组分析(英文)显示文摘目的:从大麦全基因组中鉴定AS2/LOB基因家族,并进行基因进化、基因结构、染色体定位以及组织、表达分析,为大麦ASL/LBD基因进一步功能研究与鉴定奠定基础。创新点:首次在大麦全基因组水平上分析AS2/LOB基因家族,并对部分基因的功能进行预测和分析。方法:利用大麦基因组数据库,通过生物信息学手段,鉴定大麦AS2/LOB基因家族成员;采用MEGA6软件进行系统进化树分析;利用GSDS及Map Draw工具进行基因结构及染色体定位分析;利用已有的大麦RNAseq数据进行组织表达谱分析。结论:通过全基因组分析,大麦AS2/LOB家族基因包括24个成员,在进化上分为两大类,7个亚家族,分布于大麦7条染色体上,组织表达模式具有多样性,与已经报道的ASL/LBD基因具有良好的同源性。这些信息为大麦AS2/LOB基因家族的功能分析奠定了基础。 | Bao-jian GUO Jun WANG Shen LIN Zheng TIAN Kai ZHOU Hai-ye LUAN Chao LYU Xin-zhong ZHANG Ru-gen XU | 2016 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2016，17，10： | 3 |
| 8 | Adjuvant chemotherapy may improve outcome of patients with non-small-cell lung cancer with metastasis of intrapulmonary lymph nodes after systematic dissection of N1 nodes显示文摘Objective: Survival benefit of adjuvant chemotherapy(AC) of patients with intrapulmonary lymph node(IPLN)metastasis(level 12-14) needs investigation.We evaluated the impact of AC on patients whose metastatic nodes were limited to intrapulmonary levels after systematic dissection of N1 nodes.Methods: First,155 consective cases of lung cancer confirmed as pathologic N1 were collected and evaluated.Patients received systematic dissection of N2 and N1 nodes.For patients with IPLN metastasis,survival outcomes were compared between those receiving AC and those not receiving AC.Results: In this group,112 cases(72.3%) had IPLN metastasis and 55 cases(35.5%) had N1 involvement limited to level 13-14 without further disease spread to higher levels.Patients with IPLN involvement had a better prognosis than that of patients with hilar-interlobar involvement.For the intrapulmonary N1 group(level 12-14-positive,level 10-11-negative or unknown,n=112),no survival benefit was found between the AC group and nonAC group [5-year overall survival(OS): 54.6±1.6 vs.50.4±2.4 months,P=0.177].However,76 of 112 cases for whom harvesting of level-10 and level-11 nodes was done did not show cancer involvement in pathology reports(level 12-14-positive,level 10-11 both negative),oncologic outcome was better for patients receiving AC than those not receiving AC in this subgroup(5-year OS: 57.3±1.5 vs.47.1±3.2 months,P=0.002).Conclusions: Oncologic outcome may be improved by AC for patients with involvement of N1 nodes limited to intrapulmonary levels after complete examination of N1 nodes. | Xing Wang Shi Yan Yaqi Wang Xiang Li Chao Lyu Yuzhao Wang Jia Wang Shaolei Li Lijian Zhang Yue Yang Nan Wu | 2018 | Chinese Journal of Cancer Research2018，30，6： | 2 |
| 9 | Surface sulfur vacancies enhanced electron transfer over Co-ZnS quantum dots for efficient degradation of plasticizer micropollutants by peroxymonosulfate activation显示文摘Peroxymonosulfate(PMS)activation in heterogeneous processes is a promising water treatment technology.Nevertheless,the high energy consumption and low efficiency during the reaction are ineluctable,due to electron cycling rate limitation.Herein,a new strategy is proposed based on a quantum dots(QDs)/PMS system.Co-ZnS QDs are synthesized by a water phase coprecipitation method.The inequivalent lattice-doping of Co for Zn leads to the generation of surface sulfur vacancies(SVs),which modulates the surface of the catalyst to form an electronic nonequilibrium surface.Astonishingly,the plasticizer micropollutants can be completely degraded within only tens of seconds in the Co-Zn S QDs/PMS system due to this type of surface modulation.The interfacial reaction mechanism is revealed that pollutants tend to be adsorbed on the cobalt metal sites as the electron donors,where the internal electrons of pollutants are captured by the metal species and transferred to the surface SVs.Meanwhile,PMS adsorbed on the SVs is reduced to radicals by capturing electrons,achieving effective electron recovery.Dissolved oxygen(DO)molecules are also easily attracted to catalyst defects and are reduced to O_(2)^(·-),further promoting the degradation of pollutants. | Yuting Gu Tingting Gao Fagen Zhang Chao Lu Wenrui Cao Ziwei Fu Chun Hu Lai Lyu | 2022 | Chinese Chemical Letters2022，33，8： | 2 |
| 10 | Management guidelines for primary lung cancer 2018: Chinese standards in clinical practice显示文摘Chinese guidelines for diagnosis and treatment of primary lung cancer 2018 are a set of clinical standards for screening, diagnosis and treatment of lung cancer in China (1). It covers the specialties of epidemiology, radiology, pathology, surgery, medical oncology, radiotherapy, endoscopy, nuclear medicine, and so on. The guidelines are referred to by physicians, medical students and patients, through providing comprehensive and detailed knowledge and recommendations in clinical practice on lung cancer diagnosis and treatment. | Chao Lyu Nan Wu | 2019 | Chinese Journal of Cancer Research2019，31，3： | 2 |
| 11 | Four COVID-19 Cases of New Variant B.1.351 First Emerging in South Africa in Chinese Passengers on Same Flight-Shenzhen,China,January 2021显示文摘At 04∶50 on January 1,2021,a 36-year-old Chinese project manager(Case A),a 29-year-old Chinese worker(Case B),and a 53-year-old Chinese businessman(Case C)returned from Africa(Case A and B from South Africa and Case C from Lesotho)on the same flight and tested coronavirus disease 2019(COVID-19)RNA positive by real-time polymerase chain reaction(PCR)by Baoan District People’s Hospital.Shenzhen CDC received their oral nasopharyngeal swabs packages from the hospital and retested COVID-19 RNA positive at 09∶50.Meanwhile,Case D. | Cong Cheng Lei Wang Ziquan Lyu Bo Peng Yinghui Li Dongfeng Kong Le Zuo Xiaomin Zhang Chao Yang Weiwen Liu Jia Wan Yijun Tang Junjia He Ying Wen Shule Xu Weihua Wu Ying Chen Guangnan Liu Junjie Xia Xuan Zou Renli Zhang Qinghua Hu Shujiang Mei Tiejian Feng | 2021 | China CDC weekly2021，3，8： | 2 |
| 12 | Pd/TiO2 Nanospheres with Three-dimensional Hyperstructure for Enhanced Photodegradation of Organic Dye显示文摘Pd/TiO2 nanospheres assembled from nanorods with three-dimensional hyperstructure for enlianced photodegradation of organic dye was prepared by a sample solvothemial method. Further, it was used for degradation of methyl orange(MO) under the illumination of visible-light(simulated).The results show that Pd/TiO2 with 2%(mass fraction) Pd exhibits the noticeable activity in photodegrading of MO.The detailed analysis shows that this enhancement is attributed to the reduction of the rate of electron-hole recombination and surface plasmon resonance of Pd. The high activity and good stability of the obtained Pd/TiO2 nano spheres make it a promising photocatalyst for solving the environmental pollution problems. | WANG Huan XIAO Liguang WANG Chao LIN Bin LYU Sa CHU Xuefeng CHI Yaodan YANG Xiaotian WANG Xinyan | 2019 | Chemical Research in Chinese Universities2019，35，4： | 1 |
| 13 | Integrated slipper retainer mechanism to eliminate slipper wear in high-speed axial piston pumps显示文摘he power density of axial piston pumps can greatly benefit from increasing the speed level.However,traditional slippers in axial piston pumps are exposed to continuous sliding on the swash plate,suffering from serious wear at high rotational speeds.Therefore,this paper presents a new integrated slipper retainer mechanism for high-speed axial piston pumps,which can avoid direct contact between the slippers and the swash plate and thereby eliminate slipper wear under severe operating conditions.A lubrication model was developed for this specific slipper retainer mechanism,and experiments were carried out on a pump prototype operating at high rotational speed up to 10000 r/min.Experimental results qualitatively validated the theoretical model and confirmed the effectiveness of the new slipper design. | Qun CHAO Junhui ZHANG Bing XU Qiannan WANG Fei LYU Kun LI | 2022 | Frontiers of Mechanical Engineering2022，17，1： | 1 |
| 14 | An approximate solution for electrolyte concentration distribution in physics- based Lithium-ion cell models 显示文摘 | Luo Weilin Lyu Chao Wang Lixin | 2013 | Microelectronics Reli- ability2013，53，6： | 1 |
| 15 | Thermal- electrochemical modeling and parameter sensitivity anal- ysis of Lithium-ion battery 显示文摘 | Zhang Liqiang Lyu Chao Wang Lixin | 2013 | Chemical Engineering Trans- actions2013，33，： | 1 |
| 16 | A new extension of physics-based single particle model for higher charge- discharge rates 显示文摘 | Luo Weilin Lyu Chao Wang Lixin | 2013 | Journal of Power Sources2013，241，： | 1 |
| 17 | An approxi- mate solution for electrolyte concentration distribution in physics-based lithium-ion cell models 显示文摘 | Luo Weilin Lyu Chao Wang Lixin | 2013 | Microelectron- ics Reliability2013，53，6： | 1 |
| 18 | Data-driven soft sensor development based on deep learning technique显示文摘 | Chao Shang Fan Yang Dexian Huang Wenxiang Lyu | 2014 | Journal of Process Control2014，24，3： | 1 |
| 19 | Investigation of the structural, electronic and mechanical properties of CaO–SiO_(2) compound particles in steel based on density functional theory显示文摘CaO–SiO_(2)compounds compromise one of the most common series of oxide particles in liquid steels, which could significantly affect the service performance of the steels as crack initiation sites. However, the structural, electronic, and mechanical properties of the compounds in CaO–SiO_(2)system are still not fully clarified due to the difficulties in the experiments. In this study, a thorough investigation of these properties of CaO–SiO_(2)compound particles in steels was conducted based on first-principles density functional theory. Corresponding phases were determined by thermodynamic calculation, including gamma dicalcium silicate(γ-C2S), alpha-prime(L) dicalcium silicate(αL′-C2S), alpha-prime(H) dicalcium silicate(αH′-C2S), alpha dicalcium silicate(α-C2S), rankinite(C3S2), hatrurite(C3S), wollastonite(CS), and pseudowollastonite(Ps-CS). The results showed that the calculated crystal structures of the eight phases agree well with the experimental results. All the eight phases are stable according to the calculated formation energies, and γ-C2S is the most stable. O atom contributes the most to the reactivity of these phases. The Young’s modulus of the eight phases is in the range of 100.63–132.04 GPa. Poisson’s ratio is in the range of0.249–0.281. This study provided further understanding concerning the CaO–SiO_(2)compound particles in steels and fulfilled the corresponding property database, paving the way for inclusion engineering and design in terms of fracture-resistant steels. | Chao Gu Ziyu Lyu Qin Hu Yanping Bao | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，4： | 1 |
| 20 | Identification of Hypertension Subgroups through Topological Analysis of Symptom-Based Patient Similarity显示文摘Objective:To obtain the subtypes of the clinical hypertension population based on symptoms and to explore the relationship between hypertension and comorbidities.Methods:The data set was collected from the Chinese medicine(CM)electronic medical records of 33,458 hypertension inpatients in the Affiliated Hospital of Shandong University of Traditional Chinese Medicine between July 2014 and May 2017.Then,a hypertension disease comorbidity network(HDCN)was built to investigate the complicated associations between hypertension and their comorbidities.Moreover,a hypertension patient similarity network(HPSN)was constructed with patients'shared symptoms,and 7 main hypertension patient subgroups were identified from HPSN with a community detection method to exhibit the characteristics of clinical phenotypes and molecular mechanisms.In addition,the significant symptoms,diseases,CM syndromes and pathways of each main patient subgroup were obtained by enrichment analysis.Results:The significant symptoms and diseases of these patient subgroups were associated with different damaged target organs of hypertension.Additionally,the specific phenotypic features(symptoms,diseases,and CM syndromes)were consistent with specific molecular features(pathways)in the same patient subgroup.Conclusion:The utility and comprehensiveness of disease classification based on community detection of patient networks using shared CM symptom phenotypes showed the importance of hypertension patient subgroups. | WANG Yi-fei WANG Jing-jing PENG Wei REN Yong-hao GAO Chao LI Yun-lun WANG Rui WANG Xiao-feng HAN Song-jun LYU Jia-yu HUAN Jia-ming CHEN Cui WANG Hai-yan SHU Zi-xin ZHOU Xue-zhong LI Wei | 2021 | Chinese Journal of Integrative Medicine2021，27，9： | 1 |
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