|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 皮质下小血管病诊断的共识声明显示文摘血管性认知损害是用于描述一组涉及大血管和小血管的散发性和遗传性异质性疾病的诊断术语。皮质下小血管病可导致腔隙性梗死和进行性白质损害。被称为宾斯旺格病(Binswanger's disease, BD)的进行性白质损害患者构成了从单纯血管性疾病到合并神经变性病变的疾病谱。BD患者是一个相对同质性的亚组,存在缺氧缺血、腔隙性梗死和炎症,它们协同作用破坏血脑屏障和髓鞘。通过临床、脑脊液、神经心理学和影像学检查获得的多模式疾病标记物能促进该亚组患者的鉴别。本共识声明确定了一系列基于基础病理学改变的潜在生物学标记物,这将有助于诊断以及将来协作性治疗试验的患者选择。 | Gary A Rosenberg Anders Wallin Joanna M Wardlaw Hugh S Markus Joan Montaner Leslie Wolfson Costantino Iadecola Berislav V Zlokovic Anne Joutel Martin Dichgans Marco Duering Reinhold Schmidt Amos D Korczyn Lea T Grinberg Helena C Chui Vladimir Hachinski 王训师 张劼 陈涵丰 俞娅美 徐子奇 罗本燕 | 2016 | 国际脑血管病杂志2016，24，6： | 18 |
| 2 | What exists beyond cag A and vacA? Helicobacter pylori genes in gastric diseases显示文摘Helicobacter pylori(H. pylori) infection is present in more than half the world's population and has been associated with several gastric disorders, such as gastritis, peptic ulceration, and gastric adenocarcinoma.The clinical outcome of this infection depends on host and bacterial factors where H. pylori virulence genes seem to play a relevant role. Studies of cag A and vac A genes established that they were determining factors in gastric pathogenesis. However, there are gastric cancer cases that are cag A-negative. Several other virulence genes have been searched for, but these genes remain less well known that cag A and vac A. Thus, this review aimed to establish which genes have been suggested as potentially relevant virulence factors for H. pylori-associated gastrointestinal diseases. We focused on the cag-pathogenicity island, genes with adherence and motility functions, and ice A based on the relevance shown in several studies in the literature. | Débora Menezes da Costa Eliane dos Santos Pereira Silvia Helena Barem Rabenhorst | 2015 | World Journal of Gastroenterology2015，21，37： | 6 |
| 3 | Preoperative immunonutrition in patients undergoing liver resection:A prospective randomized trial显示文摘BACKGROUND Preoperative supplementation with immunonutrients, including arginine and n-3 fatty acids, has been shown in a number of systematic reviews to reduce infectious complications in patients who have undergone gastrointestinal surgery. Limited information, however, is available on the benefits of nutritional supplementation enriched with arginine and n-3 fatty acids in patients undergoing liver resection.AIM To evaluate the effects of preoperative nutritional supplementation enriched with arginine and n-3 fatty acids on inflammatory and immunologic markers and clinical outcome in patients undergoing liver resection.METHODS Thirty-four patients undergoing liver resection were randomized to either five days of preoperative Impact? [1020 kcal/d, immunonutrition(IMN) group], or standard care [no supplementation, standard care(STD) group]. Nutritional status was measured at study entry by subjective global assessment(SGA).Functional assessments(grip strength, fatigue and performance status) were carried out at study entry, on the day prior to surgery, and on postoperative day(POD) 7 and 30. Inflammatory and immune markers were measured at study entry, on the day prior to surgery, and POD 1, 3, 5, 7, 10 and 30. Postoperative complications were recorded prospectively until POD30.RESULTS A total of 32 patients(17 IMN and 15 STD) were analysed. All except four patients were SGA class A. The plasma ratio of(eicosapentaenoic acid plus docosahexaenoic acid) to arachidonic acid was higher in IMN patients on the day prior to surgery and POD 1, 3, 5 and 7(P < 0.05). Plasma interleukin(IL)-6 concentrations were elevated in the IMN group(P = 0.017 for POD7). No treatment effect was detected for functional measures, immune response(white cell count and total lymphocytes) or markers of inflammation(C-reactive protein,tumour necrosis factor-α, IL-8, IL-10). There were 10 patients with infectious complications in the IMN group and 4 in the STD group(P = 0.087). Median hospital stay was 9(range 4–49) d in the IMN group and 8(3-34) d in the STD group(P = 0.476).CONCLUSION In well-nourished patients undergoing elective liver resection, this study failed to show any benefit of preoperative immunonutrition. | Kylie Russell Han-Guang Zhang Lyn K GillANDers Adam SJR Bartlett Helena L Fisk Philip C Calder Peter J Swan Lindsay D Plank | 2019 | World Journal of Hepatology2019，11，3： | 3 |
| 4 | Tumor necrosis factain- hibits insulin'8 stimulating effect on shcooouptake and endotheli- umdependent vasodilation in humans 显示文摘 | Christian RM Helena D Nikolaj I | 2003 | Circulation2003，108，2： | 1 |
| 5 | Improvement of tech- nological quality of eucalypt wood by heat treatment in air at 170-200℃显示文摘 | BRUNO E IDALINA D HELENA P | 2007 | Forest Products Journal2007，57，： | 1 |
| 6 | Correction of colour values of woven fabrics using changes to constructional parameters 显示文摘 | Krste D Helena G | 2004 | Autex Research Journal2004，4，4： | 1 |
| 7 | Search for genes involved in the temperature - induced gonadal sex differentiation in the tilapia, Oreochromis niloticus显示文摘 | Helena D Jean - Francois B | 2001 | Journal of Experimental Zoology2001，290，： | 1 |
| 8 | Use of regression methods for determining the re- lation between theoretical linear and spectrophotometrical colour val- ues of bicolour woven structures 显示文摘 | Helena G Krste D | 2009 | Coloration Technology2009，125，2： | 1 |
| 9 | Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice显示文摘 | María Díaz-Moreno Rafael Hortigüela Ania Gon?alves Irmina García-Carpio Gemma Manich Edurne García-Bermúdez Mireia Moreno-Estellés César Eguiluz Jordi Vilaplana Carme Pelegrí Mar?al Vilar Helena Mira | 2013 | Neurobiology of Aging2013，，： | 1 |
| 10 | Commensal bacteria (normal microflora), mucosal immunity and chronic inflammatory and autoimmune diseases显示文摘 | Helena Tlaskalov a -Hogenov d Renata Stepankova | 2004 | Immunology Letters2004，，93： | 1 |
| 11 | Late season nitrogen fertilization of soybeans: effects on leaf senescence, yield and environment显示文摘 | Flavio H GutieR Javier D S Helena R | 2004 | Nutrient Cycling in Agroecosystems2004，68，： | 1 |
| 12 | The sensitive period for male‐to‐female sex reversal begins at the embryonic stage in the Nile tilapia and is associated with the sexual genotype显示文摘 | Vincent Gennotte Charles Mélard Helena D’Cotta Jean‐Fran?ois Baroiller Carole Rougeot | 2014 | Mol. Reprod. Dev2014，，： | 1 |
| 13 | An indirect ELISA for detection of antibodies against porcine reproductive and respiratory syndrome virus using recombinant nucleocapsid protein as antigen显示文摘 | Helena D Christian M Jon D | 1997 | J Virol Methods1997，65，： | 1 |
| 14 | Structural characterization of photosystem 1] complex from red alga porphyridium cruentum retaining extrinsic subunits of the oxygen-evolving complex 显示文摘 | Ladislav B Helena H D Michal H | 2005 | European Journal of Bio- chemist2005，271，14： | 1 |
| 15 | DMRT1 expression during gonadal differentiation and spermatogenesis in the rainbow trout, Oncorhynchus mykiss显示文摘 | Oriane Marchand Marina Govoroun Helena D’Cotta Oonagh McMeel Jean-Jacques Lareyre Alain Bernot Vincent Laudet Yann Guiguen | 2000 | BBA - Gene Structure and Expression2000，，1： | 1 |
| 16 | An indirect ELISA for detection of antibodies against Porcine reproductive and respiratory syndrome virus using recombinant nucleocapsid protein as antigen显示文摘 | Helena D Christian M Jon D | 1997 | Journal of Virological Methols1997，65，： | 1 |
| 17 | Structural characterization of photosystem II complex from red alga porphyridium cruentum retaining extrinsic subunits of the oxygen-evolving complex显示文摘 | Ladislav B Helena H D Michal H | 2005 | European Journal of Biochemist2005，271，： | 1 |
| 18 | Deposition ofparticulate matter of different size fractions on leaf surfacesand in waxes of urban forest species显示文摘 | Kajetan D Robert P Helena G | 2011 | International Journalof Phytoremediation2011，13，10： | 1 |
| 19 | Exploring impact of time management services on HLA-based Petri Nets Simulation Engine显示文摘 | Kpstcha M B Kouakou D K Helena S | 2002 | Simulation Practice and Theory(S0928-4869)2002，，9： | 1 |
| 20 | Validation of a 3 - D Enhancement of the Universal Soil Loss Equation for Predication of Soil Erosion and Sediment Deposition 显示文摘 | Steven D Warren Helena Mitasova | 2005 | CATENA2005，64，23： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员