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| 1 | An experimental study of salt expansion in sodium saline soils under transient conditions显示文摘Salt expansion in sulfate saline soils that are widely distributed in northwestern China causes serious infrastructural damages under low-temperature conditions. However, the mechanism of salt expansion under low temperatures is not clear. In this study, we conducted a series of cooling experiments combined with salt crystallization to study this mechanism, and employed an ionic model to calculate the supersaturation ratio of the solution. During the experiments, the strength and the process of salt expansion were examined under different cooling rates and various crystal morphologies. The relationship between temperature and supersaturation ratio under transient conditions was also considered. Results indicate that the initial supersaturation ratio of a sodium sulfate solution is closely related to environmental conditions, and that this ratio decreases with slowing the cooling rates and stabilizing the crystal forms. Higher initial supersaturation ratios lead to an increased non-steady-state zone, resulting in less salt expansion. On the other hand, chloride ion content has a distinct influence on the crystallization supersaturation ratio of the sodium sulfate solution, and higher chloride ion content can inhibit salt expansion in sodium saline soils. These findings help explain salt expansion mechanisms in complex conditions such as seasonally frozen soils, and thus help search for improved methods of preventing salt expansion in sulfate saline soils. | WAN Xusheng YOU Zhemin WEN Haiyan William CROSSLEY | 2017 | Journal of Arid Land2017，9，6： | 9 |
| 2 | Expert consensus on the glycemic management of critically ill patients显示文摘Introduction The incidence of hyperglycemia is 40-60%in critically ill patients and is up to 60-80%in those who have undergone car-diac surgery.[1]The results of an epidemiological study in the United States showed that 28.6%of diabetic patients and 9.3%of non-diabetic patients had elevated mean daily glucose on the day of ICU admission.[2]In critically ill patients,elevated blood glucose is primarily the result of stress,and stress-induced hy-perglycemia is an independent risk factor associated with prog-nosis,regardless of a previous diagnosis of diabetes.Nutritional therapy has become an integral treatment option for patients in the ICU,[3,4]though nearly 30%of patients with enteral nu-trition and 44-50%with parenteral nutrition(PN)experience elevated glucose.[5,6]Intensive insulin therapy(IIT)is an impor-tant treatment for controlling hyperglycemia in critically ill pa-tients,but it also carries a corresponding risk of hypoglycemia. | Zhixiong Wu Jiao Liu Dong Zhang Kai Kang Xiangrong Zuo Qianghong Xu Aijun Pan Wei Fang Fen Liu You Shang Haiyan Yin Juntao Hu Jinglun Liu Jiangquan Fu Wei Zhang Yuan Zong Min Shao Feng Zhao Mei Meng Yanfei Mao Yingchuan Li Dechang Chen | 2022 | Journal of Intensive Medicine2022，2，3： | 9 |
| 3 | Defects as a factor limiting carrier mobility in WSe2: A spectroscopic investigation显示文摘二维的转变金属 dichalcogenides (TMD ) 的电的表演被结构的缺点的数字强烈影响。在这个工作,我们提供一条光分光镜的描述途径相关结构的缺点的数字和 WSe 2 设备的电的表演。electron-beam-lithographyprocessed WSe 2 的低温度的光致发光(PL ) 系列由于缺点一定的激子展出清楚的导致缺点的 PL 排出物,它将强烈降级电的表演。由采用一种 electron-beam-free 转移电极技术,我们成功地准备了包含缺点的有限数量的一台 backgated WSe 2 设备。约 200 厘米 2 | Zhangting Wu Zhongzhong Luo Yuting Shen Weiwei Zhao Wenhui Wang Haiyan Nan Xitao Guo Litao Sun Xinran Wang Yumeng You Zhenhua Ni | 2016 | Nano Research2016，9，12： | 8 |
| 4 | Approach to WTA in air combat using IAFSA-IHS algorithm显示文摘In this paper, a static weapon target assignment(WTA)problem is studied. As a critical problem in cooperative air combat,outcome of WTA directly influences the battle. Along with the cost of weapons rising rapidly, it is indispensable to design a target assignment model that can ensure minimizing targets survivability and weapons consumption simultaneously. Afterwards an algorithm named as improved artificial fish swarm algorithm-improved harmony search algorithm(IAFSA-IHS) is proposed to solve the problem. The effect of the proposed algorithm is demonstrated in numerical simulations, and results show that it performs positively in searching the optimal solution and solving the WTA problem. | LI Zhanwu CHANG Yizhe KOU Yingxin YANG Haiyan XU An LI You | 2018 | Journal of Systems Engineering and Electronics2018，29，3： | 7 |
| 5 | Epigenetic silencing of WIF - 1 in hepatocellular carcinomas显示文摘 | Yun Deng Bin Yu Qin Cheng Jie Jin Haiyan You Ronghu Ke Ning Tang Qiujin Shen Huiqun Shu Genfu Yao Zhigang Zhang Wenxin Qin | 2010 | Journal of Cancer Research and Clinical Oncology2010，，8： | 1 |
| 6 | The critical role of myeloid-derived suppressor cells and FXR activation in immune-mediated liver injury显示文摘 | Haiyan Zhang Yuan Liu Zhaolian Bian Shanshan Huang Xiaofeng Han Zhengrui You Qixia Wang Dekai Qiu Qi Miao Yanshen Peng Xiaoying Li Pietro Invernizzi Xiong Ma | 2014 | Journal of Autoimmunity2014，，： | 1 |
| 7 | On-line continu- ous flow ultrasonic extraction coupled with high performance liq- uid chromatographic separation for determination of the fla- vonoids from root of Scutellaria baicalensis Georgi 显示文摘 | You Jingyan Gao Shiqian Jin Haiyan | 2010 | J Chrom- atogr A2010，1217，12： | 1 |
| 8 | Hepatitis B virus X protein co-activates pregnane X receptor to induce the cytochrome P450 3A4 enzyme, a potential implication in hepatocarcinogenesis显示文摘 | Yongdong Niu Zheng Wu Qiujin Shen Jin Song Qin Luo Haiyan You Ganggang Shi Wenxin Qin | 2013 | Digestive and Liver Disease2013，，： | 1 |
| 9 | Probing the intrinsic optical quality of CVD grown MoS2显示文摘二维的分层的转变金属 dichalcogenides (TMD ) 的光排放效率是影响他们的 optoelectronic 性能的最重要的参数之一。由化学蒸汽免职(CVD ) 的生长参数的优化因此,完成 optoelectronic 等级质量 TMD 是高度合乎需要的。这里,我们在场系统的光致发光(PL ) 估计 CVD 成年瞬间 2 的内在的光、水晶的质量的分光镜的途径(CVD 瞬间 2) 。我们建议在作为监视 CVD 瞬间 2 的内在的光质量的一个有效方法在空和真空中测量的 PL 之间的紧张比率的使用。低温度的 PL 大小也被用来经由联系缺点的界限激子排放在瞬间 2, 评估结构的缺点,它很好与在不同温度种的瞬间 2 的地效果搬运人活动性相关。这个工作因此提供一敏感,描绘 TMD 的光性质的 noninvasive 方法,允许为 optoelectronic 设备的发展调节生长参数。 | Amina Zafar Haiyan Nan Zainab Zafar Zhangting Wu Jie Jiang Yumeng You Zhenhua Ni | 2017 | Nano Research2017，10，5： | 1 |
| 10 | Flexible free-standing polyaniline/poly(vinyl alcohol) composite electrode with good capacitance performance and shape memory behavior显示文摘The increasing demand for portable and flexible energy storage devices drives the development of flexible electrodes and electrolytes.The aim of this work is to fabricate the flexible free-standing polyaniline/poly(vinyl alcohol)(PANI/PVA)composite electrode with good capacitance performance and shape memory behavior.The electrodes were fabricated by chemical oxidation polymerization of aniline in porous PVA(P-PVA)films.The morphology,electrochemical and mechanical properties of PANI/P-PVA electrodes were studied by scanning electron microscope,cyclic voltammetry,galvanostatic charge-discharge,and tensile test etc.The results revealed that the flexible PANI/P-PVA-1 electrode had good specific capacitance of 173.86 m F cm(-2)at 1 m A cm(-2),with the capacitance retention of 70.16%after 4000 charge-discharge cycles.Besides,it had excellent heat-induced shape memory effect.The fixed shape could completely recover to its original shape within 10 s at 80℃,which is above the glass transition temperature(75.89℃)of PANI/P-PVA-1.The comparatively tensile strength(2.86 MPa)and high elongation at break(315.72%)indicated its outstanding flexibility.Up to 200 times folding had no effect on the electrochemical properties.The free-standing polymer electrodes with excellent comprehensive performance provide potential applications in flexible energy-storage devices,electronic encapsulation and high stretchable electric devices etc. | Haiyan Du Shaoze Liu Feng You Jinfeng Wang Zhe Ren Zemin Wu | 2021 | Progress in Natural Science:Materials International2021，31，4： | 1 |
| 11 | Small interfering RNA targeting the subunit ATP6L of proton pump V-ATPase overcomes chemoresistance of breast cancer cells显示文摘 | Haiyan You Jie Jin Huiqun Shu Bin Yu Angelo De Milito Francesco Lozupone Yun Deng Ning Tang Genfu Yao Stefano Fais Jianren Gu Wenxin Qin | 2009 | Cancer Letters2009，，1： | 1 |
| 12 | Hepatic stellate cells activated by acidic tumor microenvironment promote the metastasis of hepatocellular carcinoma via osteopontin显示文摘 | Jin Song Zhouhong Ge Xinrong Yang Qin Luo Cun Wang Haiyan You Tianxiang Ge Yun Deng Hechun Lin Yongqi Cui Wei Chu Ming Yao Zhigang Zhang Jianren Gu Jia Fan Wenxin Qin | 2014 | Cancer Letters2014，，： | 1 |
| 13 | The Study of Anti-UV and Anti-Solarization of Strength Synthetic Fiber Hoisting Belt 显示文摘 | Ni Haiyan Gan Yingjin You Jinti | 2012 | AdvancedMaterials Research2012，，10： | 1 |
| 14 | Small interfering RNA targeting the subunit ATP6L of proton pump V-ATPase overcomes chemoresistance of breast cancer cells显示文摘 | Haiyan You Jie Jin Huiqun Shu Bin Yu Angelo De Milito Francesco Lozupone Yun Deng Ning Tang Genfu Yao Stefano Fais Jianren Gu Wenxin Qin | 2009 | Cancer Letters2009，，1： | 1 |
| 15 | Efficacy of acupuncture therapy for post-stroke fatigue:a systematic review and Meta-analysis显示文摘OBJECTIVE:To assess the effectiveness and safety of acupuncture for post-stroke fatigue(PSF).METHODS:Eight online databases were searched to collect relevant trials of acupuncture for PSF published before April 2021.Meta-analysis was performed by using RevMan 5.4 software.The Grading of Recommendations,Assessment,Development and Evaluation system was used to assess the certainty of evidence.RESULTS:Four randomized controlled trials involving 289 PSF patients were identified and included in the systematic review.The results of the Meta-analysis revealed that acupuncture group was significantly better than routine treatment group in improving the effective rate[risk ratio(RR)=1.15,95%CI(1.01,1.33),P=0.04],reducing the FSS score[mean difference(MD)=-4.71,95%CI(-6.22,-3.20),P<0.00001]and FMA score[MD=15.60,95%CI(11.96,19.23),P<0.00001].Side effects of acupuncture were mild and rarely reported.The certainty of evidence of the outcomes based on the four trials was assessed as low.CONCLUSIONS:The existing evidence suggests acupuncture as an adjunct to routine treatment may benefit in managing fatigue in stroke patients.However,high-quality RCTs are needed to further confirm these findings. | YOU Jianyu LI Haiyan XIE Dingyi CHEN Mingren CHEN Rixin | 2023 | Journal of Traditional Chinese Medicine2023，43，1： | 1 |
| 16 | Acupuncture improves cognitive deficits and regulates the brain cell proliferation of SAMP8 mice显示文摘 | Haiyan Cheng Jianchun Yu Zhiguo Jiang Xuezhu Zhang Cunzhi Liu Yingmei Peng Fuyan Chen You Qu Yujie Jia Qingfei Tian Chuan Xiao Qin Chu Kun Nie Bohong Kan Xiaolin Hu Jingxian Han | 2007 | Neuroscience Letters2007，，2： | 1 |
| 17 | On-line con-tinuous flow ultrasonic extraction coupled with high per-formance liquid chromatographic separation for determina-tion of the flavonoids from root of Scutellaria baicalensis Georgi显示文摘 | Jingyan You Shiqian Gao Haiyan Jin | | 0，，12： | 1 |
| 18 | Research and Development on Control System of Novel Winding Machine for High-pressure FRP Pipeline显示文摘The novel winding machine adopted steam inside solidification technics,can wind,solidify and extract high- pressure fiber reinforced plastic (FRP) pipelines in one single machine.Its control system consisted of the winding and extraction subsystem and the steam inside solidification subsystem.In order to improve the control precision and stability,a real-time control method was adopted in the winding and extraction subsystem.In this method,high-precision TRIO motion controller combined with industrial personal computer (IPC) forms an open-type CNC system which supports multitask.The Modbus protocol was adopted for the communication between the IPC and TRIO motion controller.The human-machine interface (HMI) was developed with VC++6.0 and the control software of the motion controller was developed with TRIO BASIC language.In the steam in- side solidification subsystem,embedded IPC and PLC were used to realize the closed-loop control of the steam temperature and the HMI was developed with MCGS 5.1 under WinCE.Practices show that this system has the good performances of high precision, good stability and high efficiency. | YOU Bo XU Jiazhong HU Haiyan CHENG Ningbo ZHANG Qingli College of Automation,Harbin University of Science and Technology,Harbin 150080,China | 2006 | 武汉理工大学学报2006，28，S2： | 0 |
| 19 | USP1-regulated reciprocal differentiation of Th17 cells and Treg cells by deubiquitinating and stabilizing TAZ显示文摘The balance between inflammatory T helper type 17(Th17)and immunosuppressive regulatory T(Treg)cells is critical for maintaining immune homeostasis in the human body and is tightly regulated under healthy conditions.An increasing number of studies have reported that deubiquitinases(DUBs)play a vital role in regulating Th17-and Treg-cell differentiation.However,the biological functions of only a small fraction of DUBs in Th17-and Treg-cell differentiation are well defined.In this study,we identified ubiquitin-specific peptidase 1(USP1)as a vital regulator of CD4+T-cell differentiation.USP1 promoted Th17-cell differentiation but attenuated Treg-cell differentiation,thereby promoting the development of inflammatory diseases.Mechanistically,USP1 in CD4+T cells enhanced the activity of RORγt but promoted the proteasomal degradation of Foxp3 through deubiquitination and stabilization of TAZ in vitro and in vivo.Notably,ML323,a specific inhibitor of the USP1/UAF1 deubiquitinase complex,inhibited Th17-cell differentiation and promoted Treg-cell differentiation in vitro and in vivo,indicating that ML323 might be a promising candidate for the treatment of diseases associated with an imbalance between Th17 and Treg cells.Our study highlights the critical role of USP1 in regulating adaptive immune responses and suggests that USP1 might be a drug target for the treatment of diseases associated with an imbalance between Th17 and Treg cells. | Xiaotong Zhu Peng Wang Xiaoxia Zhan Yuping Zhang Junli Sheng Shitong He Yitian Chen Dingnai Nie Xiaolong You Haiyan Mai Qinghong Yu Laisheng Li Ligang Jie Shengfeng Hu | 2023 | Cellular & Molecular Immunology2023，20，3： | 0 |
| 20 | Tough adhesion and antifouling poly(vinyl alcohol)hydrogel coating on the arch wire for antibacterial adhesion显示文摘The arch wire(AW)plays an important role in providing continuous force,aligning the teeth,and excellent dental arch stability for orthodontic treatment.However,the high friction performance of the AW surface can increase bacterial adhesion and colonization,leading to oral hygiene problems.Herein,a simple method is developed to modify the surface of the orthodontic wire with a poly(vinyl alcohol)(PVA)hydrogel coating,which can improve the lubricity and antibacterial adhesion of the AW and prevent the oral hygiene problems caused by itself.The PVA hydrogel coating can toughly adhere to the surface of the AW and remarkably reduce the friction performance of the AW,and then its friction coefficient in water can reach 0.005.Under the action of brushing and bending,the PVA hydrogel coating possesses superior ultralubrication and hardly affects the mechanical properties of the stainless-steel substrate.Moreover,the PVA hydrogel coating can significantly inhibit bacterial adhesion on the surface of the AW,thereby reducing bacterial colonization and maintaining oral hygiene while correcting the shape of the mouth and jaw.Therefore,the PVA hydrogel coating exhibits tough adhesion and good antibacterial adhesion while maintaining the mechanical properties of the AW,and it is a promising antifouling coating for improving the performance of the AW. | LI MingWen TANG Chen YU XiXi SHI XinLei YU Hui YIN HaiYan YOU Min CHEN Qiang DING Xi | 2023 | Science China(Technological Sciences)2023，66，10： | 0 |
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