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| 1 | Prevalence and Factors Associated with Female Sexual Dysfunction in Beijing, China显示文摘 | Wen-Jia Lou Bo Chen Lan Zhu Shao-Mei Han Tao Xu Jing-He Lang Lei Zhang | 2017 | Chinese Medical Journal2017，，12： | 25 |
| 2 | Epidemiological characteristics of thyroid nodules and risk factors for malignant nodules: a retrospective study from 6 304 surgical cases显示文摘 | Huan Qin Wang Kun Lou Fuchen Zhang Li Huang Qingxian Han Yunfeng Sun Hancheng Zhu Lei Lin Peng Song Jun Liu Fuqiang Wang Qian Hou Weikai | 2014 | Chinese Medical Journal2014，，12： | 20 |
| 3 | Clinical characteristics and prognostic factors of patients with gastric neuroendocrine carcinoma treated with radical surgery显示文摘 | Xu Xuefeng Li Jian'ang Han Xu Shi Chenye Jin Dayong Lou Wenhui | 2014 | Chinese Medical Journal2014，，13： | 17 |
| 4 | Chemical and optical properties of aerosols and their interrelationship in winter in the megacity Shanghai of China显示文摘A field campaign on air quality was carried out in Shanghai in winter of 2012. The concentrations of NO, NO2, NOx, SO2, CO, and PM2.5increased during haze formation. The average masses of SO42-, NO3-and NH4+were 10.3, 11.7 and 6.7 μg/m3 during the haze episodes, which exceeded the average(9.2, 7.9, and 3.4 μg/m3) of these components in the non-haze days. The mean values for the aerosol scattering coefficient(b sp), aerosol absorption coefficient(b ap) and single scattering albedo(SSA) were 288.7, 27.7 and0.91 Mm-1, respectively. A bi-peak distribution was observed for the mass concentrations of CO, NO, NO2, and NOx. More sulfate was produced during daytime than that in the evening due to photochemical reactions. The mass concentration of NH4+achieved a small peak at noontime. NO3-showed lower concentrations in the afternoon and higher concentrations in the early morning. There were obvious bi-peak diurnal patterns for b sp and b ap as well as SSA. b sp and b ap showed a positive correlation with PM2.5mass concentration.(NH4)2SO4, NH4NO3, organic mass, elemental carbon and coarse mass accounted for 21.7%, 19.3%, 31.0%, 9.3% and 12.3% of the total extinction coefficient during non-haze days, and 25.6%, 24.3%, 30.1%, 8.1% and 8.2% during hazy days. Organic matter was the largest contributor to light extinction. The contribution proportions of ammonium sulfate and ammonium nitrate to light extinction were significantly higher during the hazy time than during the non-haze days. | Tingting Han Liping Qiao Min Zhou Yu Qu Jianfei Du Xingang Liu Shengrong Lou Changhong Chen Hongli Wang Fang Zhang Qing Yu Qiong Wu | 2015 | Journal of Environmental Sciences2015，27，1： | 14 |
| 5 | Benzene alkylation with methanol over phosphate modified hierarchical porous ZSM-5 with tailored acidity显示文摘The acidity and acid distribution of hierarchical porous ZSM-5 were tailored via phosphate modification. The catalytic results showed that both benzene conversion and selectivity of toluene and xylene increased with the presence of appropriate amount of phosphorus. Meanwhile, side reactions such as methanol to olefins related with the formation of by-product ethylbenzene formation and isomerization of xylene to meta-xylene were suppressed efficiently. The acid strength and sites amount of Br?nsted acid of the catalyst were crucial for improving benzene conversion and yield of xylene, whereas passivation of external surface acid sites played an important role in breaking thermodynamic equilibrium distribution of xylene isomers. | Jinghui Lyu Hualei Hu Carolyn Tait Jiayao Rui Caiyi Lou Qingtao Wang Wenwen Han Qunfeng Zhang Zhiyan Pan Xiaonian Li | 2017 | Chinese Journal of Chemical Engineering2017，25，9： | 11 |
| 6 | Jasmonic acid carboxyl methyltransferase regulates development and herbivory-induced defense response in rice显示文摘Jasmonic acid(JA) and related metabolites play a key role in plant defense and growth. JA carboxyl methyltransferase(JMT) may be involved in plant defense and development by methylating JA to methyl jasmonate(Me JA) and thus influencing the concentrations of JA and related metabolites. However, no JMT gene has been well characterized in monocotyledon defense and development at the molecular level. After we cloned a rice JMT gene,Os JMT1, whose encoding protein was localized in the cytosol, we found that the recombinant Os JMT1 protein catalyzed JA to Me JA. Os JMT1 is up-regulated in response to infestation with the brown planthopper(BPH; Nilaparvata lugens). Plants in which Os JMT1 had been overexpressed(oeJMT plants) showed reduced height and yield. These oe-JMT plants also exhibited increased Me JA levels but reduced levels of herbivore-induced JA and jasmonoyl-isoleucine(JAIle). The oe-JMT plants were more attractive to BPH female adults but showed increased resistance to BPH nymphs,probably owing to the different responses of BPH female adults and nymphs to the changes in levels of H_2O_2 and Me JA in oe-JMT plants. These results indicate that Os JMT1,by altering levels of JA and related metabolites, plays a role in regulating plant development and herbivore-induced defense responses in rice. | Jinfeng Qi Jiancai Li Xiu Han Ran Li Jianqiang Wu Haixin Yu Lingfei Hu Yutao Xiao Jing Lu Yonggen Lou | 2016 | Journal of Integrative Plant Biology2016，58，6： | 10 |
| 7 | Exogenous Hematin Alleviates Mercury-induced Oxidative Damage in the Roots of Medicago sativa显示文摘在现在的学习,我们评估了保护的效果外长他我 oxygenase-1 (HO-1 EC 1.14.99.3 ) 对在苜蓿(Medicago sativa L.) 的根的导致水银的氧化损坏的 inducer 血色素。暴露于水银(HgCl ) 的植物每根延伸的氧化,以及抑制展出了类脂化合物的重要增加。然而,到对待的 HgCl (100 omol/L ) 的补充有效地种的血色素(50 oM ) 每氧化减少了类脂化合物并且部分增加了根延伸。这些回答被一氧化碳(公司) 的水溶液的申请与 50% 浸透模仿。另外,有血色素的处理能在根纸巾导致 HO-1 抄本的有势力正式就职,作为检测 12 h 列在后面处理。而且,抗氧化剂酶,包括的谷胱甘肽 reductase , monodehydroascorbate reductase 和超级氧化物 dismutase 活动的激活,和 lipoxygenase 活动的减少,被血色素在 12 h 或 24 h 导致,它被每膜正直的氧化和损失的为类脂化合物的察觉的组织化学的染色进一步证实。而, ascorbate 过氧化物酶和 guaiacol 过氧化物酶 isozyme 活动或他们的抄本被减少分别地,显示那过氧化氢可能充当一个信号调停在处理的开始的 Hg 忍耐。血色素的改善效果是特定的,自从 CO scavenger 血红素差别颠倒了上述行动。总起来说,我们的结果建议血色素在保护植物免于导致 Hg 的氧化损坏展出一个重要角色。 | Yi Han Wei Xuan Tian Yu Wen-Bing Fang Tian-Ling Lou Yin Gao Xiao-Yue Chen XiaoXiao Wen-Biao Shen | 2007 | Journal of Integrative Plant Biology2007，49，12： | 7 |
| 8 | Medical services for sports injuries and illnesses in the Beijing 2022 Olympic Winter Games显示文摘BACKGROUND:Beijing 2022 Olympic Winter Games was the second Games held amid the COVID-19 pandemic.To a certain extent,it has altered the way sporting activities operate.There is a lack of knowledge on injury risk and illness occurrence in elite winter sport athletes amid the COVID-19 pandemic.This study aimed to describe the incidence of injuries and illnesses sustained during the XXIV Olympic Winter Games in Beijing from February 4 to 20,2022.METHODS:We recorded the daily number of injuries and illnesses among athletes reported by Beijing 2022 medical staff in the polyclinic,medical venues,and ambulance.We calculated injury and illness incidence as the number of injuries or illnesses occurring during competition or training,respectively,with incidence presented as injuries/illnesses per 100 athlete-days.RESULTS:In total,2,897 athletes from 91 nations experienced injury or illness.Beijing 2022 medical staff reported 326 injuries and 80 illnesses,equaling 11.3 injuries and 2.8 illnesses per 100 athletes over the 17-day period.Altogether,11%of the athletes incurred at least one injury and nearly 3%incurred at least one illness.The number of injured athletes was highest in the skating sports(n=104),followed by alpine skiing(n=53),ice track(n=37),freestyle skiing(n=36),and ice hockey(n=35),and was the lowest in the Nordic skiing disciplines(n=20).Of the 326 injuries,14(4.3%)led to an estimated absence from training or competition of more than 1 week.A total of 52 injured athletes were transferred to hospitals for further care.The number of athletes with illness(n=80)was the highest for skating(n=33)and Nordic skiing(n=22).A total of 50 illnesses(62.5%)were admitted to the department of dentistry/ophthalmology/otolaryngology,and the most common cause of illness was other causes,including preexisting illness and medicine(n=52,65%).CONCLUSION:Overall,11%of athletes incurred at least one injury during the Games,which is similar to the findings during the Olympic Winter Games in 2014 and 2018.Regarding illness,2%of athletes were affected,which is approximately one-third of the number affected in the 2018 Olympic Winter Games. | Peng-da Han Ding Gao Jie Liu Jing Lou Si-jia Tian Hui-xin Lian Sheng-mei Niu Lu-xi Zhang Yong Wang Jin-jun Zhang | 2022 | World Journal of Emergency Medicine2022，13，6： | 7 |
| 9 | Preparation, characterization, pharmacokinetics and anticancer effects of PEGylated β-elemene liposomes显示文摘Objective:This study aimed to develop a new polyethylene glycol(PEG)ylatedβ-elemene liposome(PEG-Lipo-β-E)and evaluate its characterization,pharmacokinetics,antitumor effects and safety in vitro and in vivo.Methods:The liposomes were prepared by ethanol injection and high-pressure micro-jet homogenization.Characterization of the liposomes was conducted,and drug content,entrapment efficiency(EE),in vitro release and stability were studied by ultra-fast liquid chromatography(UFLC)and a liquid surface method.Blood was drawn from rats to establish the pharmacokinetic parameters.The anticancer effect was evaluated in a KU-19-19 bladder cancer xenograft model.Histological analyses were performed to evaluate safety.Results:The PEG-Lipo-β-E showed good stability and was characterized as 83.31±0.181 nm in size,0.279±0.004 in polydispersity index(PDI),-21.4±1.06 mV in zeta potential,6.65±0.02 in pH,5.024±0.107 mg/mL inβ-elemene(β-E)content,and 95.53±1.712%in average EE.The Fourier transform infrared spectroscopy(FTIR)and differential scanning calorimetry(DSC)indicated the formation of PEG-Lipo-β-E.Compared to elemene injection,PEG-Lipo-β-E demonstrated a 1.75-fold decrease in clearance,a 1.62-fold increase in half-life,and a 1.76-fold increase in area under the concentration-time curves(AUCs)from 0 hour to 1.5 hours(P<0.05).PEG-Lipo-β-E also showed an enhanced anticancer effect in vivo.Histological analyses showed that there was no evidence of toxicity to the heart,kidney,liver,lung or spleen.Conclusions:The present study demonstrates PEG-Lipo-β-E as a new formulation with ease of preparation,high EE,good stability,improved bioavailability and antitumor effects. | Bingtao Zhai Qibiao Wu Wengang Wang Mingming Zhang Xuemeng Han Qiujie Li Peng Chen Xiaying Chen Xingxing Huang Guohua Li Qin Zhang Ruonan Zhang Yu Xiang Shuiping Liu Ting Duan Jianshu Lou Tian Xie Xinbing Sui | 2020 | Cancer Biology & Medicine2020，17，1： | 6 |
| 10 | Machine Learning−based Weather Support for the 2022 Winter Olympics显示文摘1.A key support for the 2022 Winter Olympics The XXIV Olympic Winter Games are scheduled to take place from 4 to 22 February 2022,followed by the Paralympic Games from 4 to 13 March,in Beijing and towns in the neighboring Hebei Province,China.Weather plays an extremely important role in the outcome of the games(Chen et al.,2018).It can not only cause a difference between a medal or not,but affect the safety of athletes.Success of the Winter Olympics will greatly depend on weather conditions at the outdoor competition venues,dealing with many weather elements including the snow surface temperature,apparent temperature,gust wind speed,snow,visibility,etc.To ensure that the scheduled games go smoothly,it is imperative to have hourly or even every 10-minutely forecasts as well as updated weather-related risk assessments at the venues for the next 240 hours.So far,the Beijing/Hebei Meteorological Observatory has already started intelligent weather forecasting at 3-km resolution based on the results of numerical weather prediction(NWP)models.However,these experiments have suggested that the current forecasting techniques are incapable of capturing the complex mountain weather variations around some venues.The forecasting capability of NWP is constrained partly by limited knowledge of the local weather mechanisms. | Jiangjiang XIA Haochen LI Yanyan KANG Chen YU Lei JI Lve WU Xiao LOU Guangxiang ZHU Zaiwen Wang Zhongwei YAN Lizhi WANG Jiang ZHU Pingwen ZHANG Min CHEN Yingxin ZHANG Lihao GAO Jiarui HAN | 2020 | Advances in Atmospheric Sciences2020，37，9： | 6 |
| 11 | Anisotropic surface roughness and shear behaviors of rough-walled plaster joints under constant normal load and constant normal stiffness conditions显示文摘In this context,we experimentally studied the anisotropic mechanical behaviors of rough-walled plaster joints using a servo-controlled direct shear apparatus under both constant normal load(CNL)and constant normal stiffness(CNS)conditions.The shear-induced variations in the normal displacement,shear stress,normal stress and sheared-off asperity mass are analyzed and correlated with the inclination angle of the critical waviness of joint surfaces.The results show that CNS condition gives rise to a smaller normal displacement due to the larger normal stress during shearing,compared with CNL condition.Under CNL conditions,there is one peak shear stress during shearing,whereas there are no peak shear stress for some cases and two peaks for other cases under CNS conditions depending on the geometry of joint surfaces.The inclination angle of the critical waviness has been verified to be capable of describing the joint surface roughness and anisotropy.The joint surface is more significantly damaged under CNS conditions than that under CNL conditions.With increment of the inclination angle of the critical waviness,both the normal displaceme nt and shea red-off asperity mass increase,following power law functions;yet the coefficient of deternination under CNL conditions is larger than that under CNS conditions.This is because the CNS condition significantly decreases the inclination angle of the critical waviness during shearing due to the larger degree of asperity degradation. | Richeng Liu Sha Lou Xiaojing Li Guansheng Han Yujing Jiang | 2020 | Journal of Rock Mechanics and Geotechnical Engineering2020，12，2： | 5 |
| 12 | PCDH17 increases the sensitivity of colorectal cancer to 5-fluorouracil treatment by inducing apoptosis and autophagic cell death显示文摘5-Fluorouracil(5-FU)is known as a first-line chemotherapeutic agent against colorectal cancer(CRC),but drug resistance occurs frequently and significantly limits its clinical success.Our previous study showed that the protocadherin 17(PCDH17)gene was frequently methylated and functioned as a tumor suppressor in CRC.However,the relationship between PCDH17 and 5-FU resistance in CRC remains unclear.Here,we revealed that PCDH17 was more highly expressed in 5-FU-sensitive CRC tissues than in 5-FU-resistant CRC tissues,and high expression of PCDH17 was correlated with high BECN1 expression.Moreover,this expression profile contributed to superior prognosis and increased survival in CRC patients.Restoring PCDH17 expression augmented the 5-FU sensitivity of CRC in vitro and in vivo by promoting apoptosis and autophagic cell death.Furthermore,autophagy played a dominant role in PCDH17-induced cell death,as an autophagy inhibitor blocked cell death to a greater extent than the pancaspase inhibitor Z-VAD-FMK.PCDH17 inhibition by siRNA decreased the autophagy response and 5-FU sensitivity.Mechanistically,we showed that c-Jun NH2-terminal kinase(JNK)activation was a key determinant in PCDH17-induced autophagy.The compound SP600125,an inhibitor of JNK,suppressed autophagy and 5-FU-induced cell death in PCDH17-reexpressing CRC cells.Taken together,our findings suggest for the first time that PCDH17 increases the sensitivity of CRC to 5-FU treatment by inducing apoptosis and JNK-dependent autophagic cell death.PCDH17 may be a potential prognostic marker for predicting 5-FU sensitivity in CRC patients. | Shuiping Liu Haoming Lin Da Wang Qiang Li Hong Luo Guoxiong Li Xiaohui Chen Yongqiang Li Peng Chen Bingtao Zhai Wengang Wang Ruonan Zhang Bi Chen Mingming Zhang Xuemeng Han Qiujie Li Liuxi Chen Ying Liu Xiaying Chen Guohua Li Yu Xiang Ting Duan Jiao Feng Jianshu Lou Xingxing Huang Qin Zhang Ting Pan Lili Yan Ting Jin Wenzheng Zhang Lvjia Zhuo Yitian Sun Tian Xie Xinbing Sui | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 4 |
| 13 | Silicon-coated fibrous network of carbon nanotube/iron towards stable and wideband electromagnetic wave absorption显示文摘Materials that can absorb electromagnetic(EM)wave have garnered increased attention in recent years due to their potential to mitigate the ever increasing environmental pollution by EM waves.Thanks to recent advances in micro/nanofabrication,a variety of magnetic metal-based EM absorbers have been reported.The design and synthesis of EM absorbers that exhibit efficient and wide-band absorption at small thicknesses,however,remains elusive.Here we report the design of fibrous nanostructures consisting of magnetic iron(Fe)nanoparticles and carbon nanotubes(CNTs),which exhibits a wide-band EM absorption(3.8 GHz)while maintain the thickness at 1.2 mm.In our work,we created a novel core-shell structure by immersing the highly fibrous CNT-Fe structure into solid-state silicon(SiO)matrix.Finally,the SiO-coated CNT-Fe structures exhibit good stability against air-induced oxidation and acid corrosion while maintaining high EM absorption.Overall,the results reported in this study present new avenues to absorb EM from ambient air.We believe that our work elevates the utility of EM absorbers to real-world applications such as anti-acid and oxidation ability. | Xiaodi Zhou He Han Yuchao Wang Cheng Zhang Hualiang Lv Zhichao Lou | 2022 | Journal of Materials Science & Technology2022，，26： | 4 |
| 14 | Correlations of PCBs, DIOXIN, and PBDE with TSH in Children's Blood in Areas of Computer E-waste Recycling显示文摘Objective To study correlations of polychlorinated biphenyls (PCBs), DIOXIN, and polybrominated diphenyl ethers (PBDE) with thyroid stimulating hormone(TSH) in children, and assess the impact on children's health. Methods Three hundred and sixty nine children aged from 6 to 8, including 195 from Luqiao, the computer E‐waste recycling area, and 174 from Longyou, the control area, were selected for this investigation to elucidate the correlation of PCBs, DIOXIN, and PBDE with TSH in children's blood samples. The children had a physical examination and their blood levels of PCBs, DIOXIN, PBDE, and TSH were detected after sample collection. Results In the E‐waste recycling area, the contents of PCBs, PBDE, DIOXIN, and TSH in the blood samples of children were 484.00±84.86 ng·g ‐1 lipid weight, 664.28±262.38 ng·g ‐1 lipid weight, 26.00±19.58 ng·g ‐1 lipid weight and 1.88±0.42 μIU/mL (serum) respectively, while in the control area, the PCBs, PBDE, DIOXIN, and TSH contents were 255.38±95 ng·g ‐1 lipid weight, 375.81±262.43 ng·g ‐1 lipid weight, 39.64±31.86 ng·g ‐1 lipid weight, and 3.31±1.04 μIU/mL respectively. Conclusion The health status of children in the control area are better than that in the contaminated area. Among children who are exposed to persistent organic pollutants, the pollutant content increases significantly in their serum, and the distribution of TSH levels in their bodies are also affected. | HAN GuanGen DING GangQiang LOU XiaoMing WANG XiaoFeng HAN JianLong SHEN HaiTao ZHOU Yu DU LeYan | 2011 | Biomedical and Environmental Sciences2011，24，2： | 4 |
| 15 | Liquid-liquid phase separation by SARS-CoV-2 nucleocapsid protein and RNA显示文摘Dear Editor,The COVID-19 pandemic worldwide is caused by a novel coronavirus SARS-CoV-2(the severe acute respiratory syndrome coronavirus 2).1 After viral invasion into the host cells,the〜30 kb viral genome RNA injected is translated into structural and nonstructural proteins to replicate viral genome and assemble more viral particles.Many copies of nucleocapsid(N)protein can bind to viral genome RNA and pack it into^100 nm particles,assisting membrane(M)and envelope(E)proteins to efficiently assemble the viral envelope.2 The exact molecular mechanism by which N protein packs up the viral genome still remains elusive. | Hui Chen Yang Cui Xuling Han Wei Hu Min Sun Yong Zhang Pei-Hui Wang Guangtao Song Wei Chen Jizhong Lou | 2020 | Cell Research2020，30，12： | 3 |
| 16 | Rapid Detection of Sildenafil Drugs in Liquid Nutraceuticals Based on Surface-Enhanced Raman Spectroscopy Technology显示文摘在这研究,提高表面的拉曼光谱学(重量的单位) 技术被用来很快检测非法增加的 sildenafil 药。由密度的详细归属分析功能的理论(DFT ) 被用来指导特定的实验。拉曼信号从银胶体(Ag 关口) 被获得底层,和他们面对矿物质盐增加了,钾碘化物(KI ) 。这些方法在象 1 獳? 敷椠汬獵牴瑡 ? 桴 ? 潰整瑮慩?景琠敨渠睥栠略楲瑳捩猠档浥 e 一样低的水的答案检测了 | Hang Zhao Wuliji Hasi Lin Bao Siqingaowa Han Xuanyu Sha Jia Sun Xiutao Lou Dianyang Lin Zhiwei Lv | 2017 | Chinese Journal of Chemistry2017，35，10： | 3 |
| 17 | Two haplotype-resolved,gap-free genome assemblies for Actinidia latifolia and Actinidia chinensis shed light on the regulatory mechanisms of vitamin C and sucrose metabolism in kiwifruit显示文摘Kiwifruit is a recently domesticated horticultural fruit crop with substantial economic and nutritional value,especially because of the high content of vitamin C in its fruit.In this study,we de novo assembled two telomere-to-telomere kiwifruit genomes from Actinidia chinensis var.‘Donghong’(DH)and Actinidia latifolia‘Kuoye’(KY),with total lengths of 608327852 and 640561626 bp for 29 chromosomes,respectively.With a burst of structural variants involving inversion,translocations,and duplications within 8.39 million years,the metabolite content of DH and KY exhibited differences in saccharides,lignans,and vitamins.A regulatory ERF098 transcription factor family has expanded in KY and Actinidia eriantha,both of which have ultra-high vitamin C content.With each assembly phased into two complete haplotypes,we identified allelic variations between two sets of haplotypes,leading to protein sequence variations in 26494 and 27773 gene loci and allele-specific expression of 4687 and 12238 homozygous gene pairs.Synchronized metabolome and transcriptome changes during DH fruit development revealed the same dynamic patterns in expression levels and metabolite contents;free fatty acids and flavonols accumulated in the early stages,but sugar substances and amino acids accumulated in the late stages.The AcSWEET9b gene that exhibits allelic dominance was further identified to positively correlate with high sucrose content in fruit.Compared with wild varieties and other Actinidia species,AcSWEET9b promoters were selected in red-flesh kiwifruits that have increased fruit sucrose content,providing a possible explanation on why red-flesh kiwifruits are sweeter.Collectively,these two gap-free kiwifruit genomes provide a valuable genetic resource for investigating domestication mechanisms and genome-based breeding of kiwifruit. | Xue Han Yilin Zhang Qiong Zhang Ni Ma Xiaoying Liu Wenjing Tao Zhiying Lou Caihong Zhong Xing Wang Deng Dawei Li Hang He | 2023 | Molecular Plant2023，16，2： | 3 |
| 18 | THE THEORETICAL STUDIES OF PRODUCT ALIGNMENT OF THE REACTIONS OF Na,F WITH CH_3I显示文摘The NaI and IF product rotational alignment of the reactionsof Na,F+CH3I has been theoretically studied in a LEPS PES.Theproduct alignment versus the relative translational energy of the reactantshas been obtained. | Ke Li HAN Guo Zhong HE Nan Quan LOU State Key Laboratory of Molecular Reaction Dynamics,Dalian Institute of Chemical Physics,CAS,Dalian 116012,China | 1993 | Chinese Chemical Letters1993，4，6： | 3 |
| 19 | The chromosome-scale genome of Phoebe bournei reveals contrasting fates of terpene synthase (TPS)-a and TPS-b subfamilies显示文摘Terpenoids,including aromatic volatile monoterpenoids and sesquiterpenoids,function in defense against pathogens and herbivores.Phoebe trees are remarkable for their scented wood and decay resistance.Unlike other Lauraceae species investigated to date,Phoebe species predominantly accumulate sesquiterpenoids instead of monoterpenoids.Limited genomic data restrict the elucidation of terpenoid variation and functions.Here,we present a chromosome-scale genome assembly of a Lauraceae tree,Phoebe bournei,and identify 72 full-length terpene synthase(TPS)genes.Genome-level comparison shows pervasive lineage-specific duplication and contraction of TPS subfamilies,which have contributed to the extreme terpenoid variation within Lauraceae species.Although the TPS-a and TPS-b subfamilies were both expanded via tandem duplication in P.bournei,more TPS-a copies were retained and constitutively expressed,whereas more TPS-b copies were lost.The TPS-a genes on chromosome 8 functionally diverged to synthesize eight highly accumulated sesquiterpenes in P.bournei.The essential oil of P.bournei and its main component,b-caryophyllene,exhibited antifungal activities against the three most widespread canker pathogens of trees.The TPS-a and TPS-b subfamilies have experienced contrasting fates over the evolution of P.bournei.The abundant sesquiterpenoids produced by TPS-a proteins contribute to the excellent pathogen resistance of P.bournei trees.Overall,this study sheds light on the evolution and adaptation of terpenoids in Lauraceae and provides valuable resources for boosting plant immunity against pathogens in various trees and crops. | Xiao Han Junhong Zhang Shuang Han Sun Li Chong Guanliang Meng Minyan Song Yang Wang Shengcai Zhou Chengcheng Liu Luhuan Lou Xiongzhen Lou Longjun Cheng Erpei Lin Huahong Huang Qi Yang Zaikang Tong | 2022 | Plant Communications2022，3，6： | 3 |
| 20 | Fiber gas sensor-integrated smart face mask for roomtemperature distinguishing of target gases显示文摘小、便携式、便宜的便携煤气的传感器在人的健康并且环境监视的即时察觉有大潜在的申请。在这个工作,我们与围单人赛的碳制作了灵活纤维气体传感器 nanotube (SWCNT ) ,多围的碳 nanotube (MWCNT ) ,和 ZnO 量察觉到元素的装饰点的 SWCNT (SWCNTs@ZnO ) 。这些灵活纤维气体传感器能在房间温度被操作与好敏感和恢复时间检测目标气体。他们也展出了优异长期的稳定性,以及好设备机械弯曲能力和坚韧性。把这些灵活煤气的传感器集成到脸面具,制作的便携的聪明的脸面具能被用来有选择地检测 C 2 H 5 哦,由与不同颜色读相应 LEDs 的 HCHO,和 NH 3 。如此的脸面具在新窗户中在事情和便携 electronics.Open | Zhiyi Gao Zhoe n g Lou Shuai Chen La Li Kai Jiang Zuoling Fu Wei Han Guozhen Shen | 2018 | Nano Research2018，11，1： | 3 |
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