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| 1 | Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis显示文摘在哺乳动物的精子发生被 piRNA 表示的二个波浪描绘:一个人对应于负责的经典 piRNAs 因为 silencing retrotransponsons 和第二个波浪主要在 pachytene spermatocytes 从 nontransposon intergenic 区域被导出,但是这些 pachytene piRNAs 的功能大部分是未知的。这里,我们在在老鼠伸长指示巨大的 mRNA 消除报导 pachytene piRNAs 的参与 spermatids (ES ) 。我们证明包含鼠科的 PIWI (MIWI ) 和 deadenylase CAF1 的导致 piRNA 的 silencing 建筑群(pi-RISC ) 有选择地在 ES 被装配,它负责经由在体的房间类似于 miRNAs 的行动的机制导致 mRNA deadenylation 和腐烂。如此的一个高度安排的节目看起来充分利用 pachytene piRNAs 的能力从 nontransposon intergenic 区域导出的多样化的指向的庞大的全部剧目。这些调查结果建议 pachytene piRNAs 负责为精子生产作准备,从 ES 使广阔细胞的节目失去活性。 | Lan-Tao Gou Peng Dai Jian-Hua Yang Yuanchao Xue Yun-Ping Hu Yu Zhou Jun-Yan Kang Xin Wang Hairi Li Min-Min Hua Shuang Zhao Si-Da Hu Li-Gang Wu Hui-Juan Shi Yong Li Xiang-Dong Fu Liang-Hu Qu En-Duo Wang Mo-Fang Liu | 2014 | Cell Research2014，24，6： | 39 |
| 2 | Scientific design and preliminary results of three-dimensional variational data assimilation system of GRAPES显示文摘The scientific design and preliminary results of the data assimilation component of the Global-Regional Prediction and Assimilation System (GRAPES) recently developed in China Meteorological Administration (CMA) are presented in this paper. This is a three-dimensional variational (3DVar) assimilation system set up on global and regional grid meshes favorable for direct assimilation of the space-based remote sensing data and matching the frame work of the prediction model GRAPES. The state variables are assumed to decompose balanced and unbalanced components. By introducing a simple transformation from the state variables to the control variables with a recursive or spectral filter, the convergence rate of iteration for minimization of the cost function in 3DVar is greatly accelerated. The definition of dynamical balance depends on the characteristic scale of the circulation considered. The ratio of the balanced to the unbalanced parts is controlled by the prescribed statistics of background errors. Idealized trials produce the same results as the analytic solution. The results of real data case studies show the capability of the system to improve analysis compared to the traditional schemes. Finally, further development of the system is discussed. | XUE JiShan ZHUANG ShiYu ZHU GuoFu ZHANG Hua LIU ZhiQuan LIU Yan ZHUANG ZhaoRong | 2008 | Chinese Science Bulletin2008，53，22： | 33 |
| 3 | Outbreak of Dengue Fever in Central China,2013显示文摘In 2013,the first dengue fever(DF) outbreak in central China was reported in the central of Henan province,northern temperate regions,although they have been sequentially recorded in Southern China.106 suspected DF cases were reported and 73 patients were confirmed dengue virus type 3(DEN-3) infections.62/392(15.8%) local health persons showed DEN antibodies positive.To this day Henan is the northernmost province in China which has been reported about outbreak of DF and what is important is that it warns us the endemic range of DF has been expanded geographically in China. | HUANG Xue Yong MA Hong Xia WANG Hai Feng DU Yan Hua SU Jia LI Xing Le TANG Xiao Yan MA Hong Peng ZU Bing Can ZHANG Qiao Hong CHEN Hao Min XU Bian Li | 2014 | Biomedical and Environmental Sciences2014，27，11： | 30 |
| 4 | The Association of Maternal Body Composition and Dietary Intake with the Risk of Gestational Diabetes Mellitus during the Second Trimester in a Cohort of Chinese Pregnant Women显示文摘Objective To investigate the association of maternal body composition and dietary intake with the risk of gestational diabetes mellitus(GDM). Methods A total 154 GDM subjects and 981 controls were enrolled in a prospective cohort study in 11 hospitals from May 20, 2012 to December 31, 2013. Bioelectrical impedance analysis and dietary surveys were used to determine body composition and to evaluate the intake of nutrients in subjects at 21-24 weeks' gestation(WG). Logistic regression analysis was applied to explore the relationships of maternal body composition and dietary intake with the risk of GDM morbidity. Results Age, pre-pregnant body weight(BW), and body mass index(BMI) were associated with increased risk of GDM. Fat mass(FM), fat mass percentage(FMP), extracellular water(ECW), BMI, BW, energy, protein, fat, and carbohydrates at 21-24 WG were associated with an increased risk of GDM. In contrast, fat free mass(FFM), muscular mass(MM), and intracellular water(ICW) were associated with a decreased risk of GDM. Conclusion Maternal body composition and dietary intake during the second trimester of pregnancy were associated with the risk of GDM morbidity. | Xu Qing Gao Zhi Ying Li Li Ming Wang Lu Zhang Qian Teng Yue Zhao Xia Ge Sheng Jing Hong Jiang Yang Yong Tao Liu Xiao Jun Lyu Chun Jian Mao Lun Yu Xiao Ming Liu Ying Hua Kong Ai Jing Yang Xue Yan Liu Zhao Zhang Yong Wang Jin Zhang Xin Sheng Xue Chang Yong Lu Yan Ping | 2016 | Biomedical and Environmental Sciences2016，29，1： | 29 |
| 5 | The linkage maps of Dendrobium species based on RAPD and SRAP markers显示文摘Dendrobium plants are used commonly as tonic herbs and health food in many Asian countries,especially in China.Here we report the genetic map construction of two Dendrobium species with a double pseudo-testcross strategy using random amplified polymorphic DNA(RAPD) and sequence-related amplified polymorphism(SRAP) markers.A F1 mapping population of 90 individuals was developed from a cross between D.officinale and D.hercoglossum.A total of 307 markers,including 209 RAPD and 98 SRAP,were identified and used for genetic linkage group(LG) analysis.The D.officinale linkage map consisted of 11 major linkage groups and 3 doublets,which covered 629.4 cM by a total of 62 markers with an average locus distance of 11.2 cM between two adjacent markers.The D.hercoglossum linkage map contained 112 markers mapped on 15 major and 4 minor linkage groups,spanning a total length of 1,304.6 cM with an average distance of 11.6 cM between two adjacent markers.The maps constructed in this study covered 92.7% and 82.7% of the D.hercoglossum and D.officinale genomes respectively,providing an important basis for the mapping of horticultural and medicinal traits and for the application of marker-assisted selection in Dendrobium breeding program. | Dawei Xue Shangguo Feng Hongyan Zhao Hua Jiang Bo Shen Nongnong Shi Jiangjie Lu Junjun Liu Huizhong Wang | 2010 | Journal of Genetics and Genomics2010，37，3： | 26 |
| 6 | Chronic ankle instability is associated with proprioception deficits:A systematic review and meta-analysis显示文摘Background:Acute ankle injury causes damage to joint mechanoreceptors and deafferentation and contributes to proprioception deficits in patients with chronic ankle instability(CAI).We aimed to explore whether deficits of proprioception,including kinesthesia and joint position sense(JPS),exist in patients with CAI when compared with the uninjured contralateral side and healthy people.We hypothesized that proprioception deficits did exist in patients with CAI and that the deficits varied by test methodologies.Methods:The study was a systematic review and meta-analysis.We identified studies that compared kinesthesia or JPS in patients with CAI with the uninjured contralateral side or with healthy controls.Meta-analyses were conducted for the studies with similar test procedures,and narrative syntheses were undertaken for the rest.Results:A total of 7731 studies were identified,of which 30 were included for review.A total of 21 studies were eligible for meta-analysis.Compared with the contralateral side,patients with CAI had ankle kinesthesia deficits in inversion and plantarflexion,with a standardized mean difference(SMD)of 0.41 and 0.92,respectively,and active and passive JPS deficits in inversion(SMD=0.92 and 0.72,respectively).Compared with healthy people,patients with CAI had ankle kinesthesia deficits in inversion and eversion(SMD=0.64 and 0.76,respectively),and active JPS deficits in inversion and eversion(SMD=1.00 and 4.82,respectively).Proprioception deficits in the knee and shoulder of patients with CAI were not statistically significant.Conclusion:Proprioception,including both kinesthesia and JPS,of the injured ankle of patients with CAI was impaired,compared with the uninjured contralateral limbs and healthy people.Proprioception varied depending on different movement directions and test methodologies.The use of more detailed measurements of proprioception and interventions for restoring the deficits are recommended in the clinical management of CAI. | Xiao’ao Xue Tengjia Ma Qianru Li Yujie Song Yinghui Hua | 2021 | Journal of Sport and Health Science2021，10，2： | 21 |
| 7 | Celastrus orbiculatus extract induces mitochondrial-mediated apoptosis in human hepatocellular carcinoma cells显示文摘OBJECTIVE:To investigate the apoptotic effects and underlying molecular mechanisms of Celastrus orbiculatus(C.orbiculatus) extract in human hepatocellular carcinoma cells.METHODS:Human hepatocellular carcinoma cells(HCCLM6) were treated with C.orbiculatus extract(COE) at different nontoxic concentrations(10,20,40,80,and 160 μg/mL).The effect of COE on HC-CLM6 viability was examined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT) assays.Cellular apoptosis following COE treatment was assessed by flow cytometry and western blot analysis.RESULTS:COE significantly inhibited cell viability and induced apoptosis of HCCLM6 cells in a dose-dependent manner.Apoptosis was accompanied by increased Bax expression and decreased Bcl-2 expression.In addition,COE treatment led to the release of cytochrome c,activation of caspase-3,and cleavage of poly(ADP-ribose) polymerase(PARP).Furthermore,activation of extracellular signal-regulated kinase(ERK),p38 kinase,and c-Jun N-terminal kinase(JNK) phosphorylation,and down-regulation of Akt phosphorylation was observed.CONCLUSION:COE induces mitochondrial-mediated,caspase-dependent apoptosis in HCCLM6 cells,which might be attributed to the activation of mitogen-activated protein kinase(MAPK) and inhibition of Akt signaling pathways.These data suggest that COE may be a potential treatment for human hepatocellular carcinoma. | Hua Zhang Yayun Qian Yanqing Liu Guoqing Li Pingfang Cui Yaodong Zhu Hui Ma Xue Ji Shiyu Guo Hisamits Tadashi | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 18 |
| 8 | WHOLE BODY DIFFUSION WEIGHTED IMAGING:A NEW ERA OF ONCOLOGICAL RADIOLOGY显示文摘Cancer has become the leading cause of mortality in the urban area of China. Whole body diffusion weighted imaging (WB-DWI), also known as virtual positron emission tomography, has gradually become accepted as an image tool in tumor localization, characterization, staging and monitoring response to therapy or tumor recurrence. Our article aimed to summarize the limited initial clinical use of WB-DWI in the referred area, and to analyze the most potential advantage of WB-DWI in therapeutic monitoring and tumor staging. WB-DWI as a highly sensitive, completely non-invasive, well-tolerated and low price technique has a promising furture in tumor assessment. Profound clinical study is necessary for its further application improvement. | Zheng-yu Jin Hua-dan Xue Hua Tao | 2008 | Chinese Medical Sciences Journal2008，23，3： | 16 |
| 9 | A VERTICAL 2D MATHEMATICAL MODEL FOR HYDRODYNAMIC FLOWS WITH FREE SURFACE IN σ COORDINATE显示文摘Numerical models with hydrostatic pressure have been widely utilized in studying flows in rivers, estuaries and coastal areas. The hydrostatic assumption is valid for the large-scale surface flows where the vertical acceleration can be ignored, but for some particular cases the hydrodynamic pressure is important. In this paper, a vertical 2D mathematical model with non-hydrostatic pressure was implemented in the σ coordinate. A fractional step method was used to enable the pressure to be decomposed into hydrostatic and hydrodynamic components and the predictor-corrector approach was applied to integration in time domain. Finally, several computational cases were studied to validate the importance of contributions of the hydrodynamic pressure. | ZHANG Jing-xin LIU Hua XUE Lei-ping | 2006 | Journal of Hydrodynamics2006，18，1： | 15 |
| 10 | Distribution of gas hydrate reservoir in the first production test region of the Shenhu area,South China Sea显示文摘In May and July of 2017,China Geological Survey (CGS),and Guangzhou Marine Geological Survey (GMGS)carried out a production test of gas hydrate in the Shenhu area of the South China Sea and acquired a breakthrough of two months continuous gas production and nearly 3.1×10^5 m^3 of production. The gas hydrate reservoir in the Shenhu area of China,is mainly composed of fine-grained clay silt with low permeability,and very difficult for exploitation,which is very different from those discovered in the USA,and Canada (both are conglomerate),Japan (generally, coarse sand)and India (fracture-filled gas hydrate).Based on 3D seismic data preserved-amplitude processing and fine imaging,combined with logging-while-drilling (LWD)and core analysis data,this paper discusses the identification and reservoir characterization of gas hydrate orebodies in the Shenhu production test area.We also describe the distribution characteristics of the gas hydrate deposits and provided reliable data support for the optimization of the production well location.Through BSR feature recognition,seismic attribute analysis, model based seismic inversion and gas hydrate reservoir characterization,this paper describes two relatively independent gas hydrate orebodies in the Shenhu area,which are distributed in the north-south strip and tend to be thicker in the middle and thinner at the edge.The effective thickness of one orebody is bigger but the distribution area is relatively small.The model calculation results show that the distribution area of the gas hydrate orebody controlled by W 18/W 19 is about 11.24 km^2,with an average thickness of 19 m and a maximum thickness of 39 m,and the distribution area of the gas hydrate orebody controlled by W11/W17 is about 6.42 km^2,with an average thickness of 26 m and a maximum thickness of 90 m. | Ru-wei Zhang Jing-an Lu Pen-fei Wen Zeng-gui Kuang Bao-jin Zhang Hua Xue Yun-xia Xu Xi Chen | 2018 | China Geology2018，1，4： | 15 |
| 11 | Super absorbent polymer seed coatings promote seed germinationand seedling growth of Caragana korshinskii in drought显示文摘Coating seeds with water absorbent materials can improve their survival, especially for those planted indrought or barren areas. In this study, effects of five kinds of super absorbent polymers (SAPs) on seed germinationand seedling growth of Caragana korshinskii under drought conditions were investigated. Our results showed that SAPcoatings could significantly improve the percentage and energy of seed germination, as well as reduce the relativeelectrical conductivity (REC), proline, malondialdehyde (MDA), H202 content, and peroxidase (POD) activity duringgermination. These results implied that seeds could uptake moisture from SAP coatings to alleviate drought-inducedoxidative stress and membrane damage, thus exhibiting a better vigor and germination performance. After coating C.korshinskii seeds with SAPs, more seedlings emerged and grew better. Under the combined influence of the waterabsorption capacity of SAP and other factors, the efficiencies of five SAP coatings are in the sequence D〉E〉B〉A〉C.The function of the SAP coating on promoting seedling survival was confirmed in Mu Us Sandy Land in Ordos, InnerMongolia Autonomous Region, China. The average seedling number of SAP D-coated seeds increased twofold on thatof naked seeds. Our results are expected to be helpful in understanding and utilizing SAP seed coatings in improvingplant survival under drought conditions. | Li-qiang SU Jia-guo LI Hua XUE Xiao-feng WANG | 2017 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2017，18，8： | 15 |
| 12 | Application of a support vector machine for prediction of slope stability显示文摘Slope stability estimation is an engineering problem that involves several parameters. To address these problems, a hybrid model based on the combination of support vector machine(SVM) and particle swarm optimization(PSO) is proposed in this study to improve the forecasting performance. PSO was employed in selecting the appropriate SVM parameters to enhance the forecasting accuracy. Several important parameters, including the magnitude of unit weight, cohesion, angle of internal friction, slope angle, height, pore water pressure coefficient, were used as the input parameters, while the status of slope was the output parameter. The results show that the PSO-SVM is a powerful computational tool that can be used to predict the slope stability. | XUE Xin Hua YANG Xing Guo CHEN Xin | 2014 | Science China(Technological Sciences)2014，57，12： | 13 |
| 13 | Seroepidemiological Investigation of Lyme Disease and Human Granulocytic Anaplasmosis among People Living in Forest Areas of Eight Provinces in China显示文摘Objective Lyme disease and Human granulocytic anaplasmosis are tick‐borne diseases caused by Borrelia burgdorferi and Anaplasma phagocytophilum respectively. We have investigated infection and co-infection of the two diseases in the population of forest areas of eight provinces in China by measuring seroprevalence of antibodies against B. burgdorferi and A. phagocytophilum. Methods Forest areas in 8 provinces were chosen for investigation using whole sampling and questionnaire survey methods. 3 669 serum samples from people in the forest areas were tested for the presence of antibodies by indirect immunofluorescent assay (IFA). Results Seroprevalence against B. burgdorferi was 3% to 15% and against A. phagocytophilum was 2% to 18% in the study sites in the 8 provinces in China. We also found co-infection of B. burgdorferi and A. phagocytophilum in 7 of the 8 provinces (the exception being the Miyun area in Beijing). The seroprevalence for both B. burgdorferi and A. phagocytophilum was significantly higher among people exposed to ticks than among people who were not exposed to ticks. Conclusion We conclude that both pathogens are endemic in the forest areas in the eight provinces, but the prevalence of B. burgdorferi and A. phagocytophilum differs between the provinces. | HAO Qin GENG Zhen HOU Xue Xia TIAN Zhen YANG Xiu Jun JIANG Wei Jia SHI Yan ZHAN Zhi Fei LI Guo Hua YU De Shan WANG Hua Yong XU Jian Guo WAN Kang Lin | 2013 | Biomedical and Environmental Sciences2013，26，3： | 13 |
| 14 | Dapper1 promotes autophagy by enhancing the Beclinl -Vps34-Atg14L complex formation显示文摘 | Benvu Ma Weipeng Cao Wenxia Li Chan Gao Zhen Qi Yan Zhao Jun Du Hua Xue Junya Peng Jun Wen Hua Chen Yuanheng Ning Lei Huang Hong Zhang Xiang Gao Li Yu Ye-Guang Chen | 2014 | Cell Research2014，24，8： | 12 |
| 15 | Information flow and controlling in regularization inversion of quantitative remote sensing显示文摘In order to minimize uncertainty of the inversed parameters to the largest extent by making full use of the limited information in remote sensing data, it is necessary to understand what the information flow in quantitative remote sensing model inversion is, thus control the information flow. Aiming at this, the paper takes the linear kernel-driven model inversion as an example. At first, the information flow in different inversion methods is calculated and analyzed, then the effect of information flow controlled by multi-stage inversion strategy is studied, finally, an information matrix based on USM is defined to control information flow in inversion. It shows that using Shannon entropy decrease of the inversed parameters can express information flow more properly. Changing the weight of a priori knowledge in inversion or fixing parameters and partitioning datasets in multi-stage inversion strategy can control information flow. In regularization inversion of remote sensing, information matrix based on USM may be a better tool for quantitatively controlling information flow. | YANG Hua, XU Wangli, ZHAO Hongrui, CHEN Xue & WANG Jindi Research Center for Remote Sensing and GIS, School of Geography, Beijing Normal University, State Key Laboratory of Remote Sensing Science, Beijing Key Laboratory for Remote Sensing of Environment and Digital Cities, Beijing 100875, China Department of Mathematics, Beijing Normal University, Beijing 100875, China | 2005 | Science China Earth Sciences2005，48，1： | 12 |
| 16 | Hyperbaric Oxygen Treatment Improves Hearing Level via Attenuating TLR4/NF-κB Mediated Inflammation in Sudden Sensorineural Hearing Loss Patients显示文摘Objective Hyperbaric oxygen treatment(HBOT)has demonstrated efficacy in improving hearing levels of patients with idiopathic sudden sensorineural hearing loss(ISSHL);however,the underlying mechanisms are not well understood.HBOT alleviates the inflammatory response,which is mediated by Toll-like receptor(TLR)4 and nuclear factor(NF)-κB.In this study we investigated whether HBOT attenuates inflammation in ISHHL patients via alteration of TLR4 and NF-κB expression.Methods ISHHL patients(n=120)and healthy control subjects(n=20)were enrolled in this study.Patients were randomly divided into medicine group treated with medicine only(n=60)and HBO group receiving both HBOT and medicine(n=60).Audiometric testing was performed pre-and posttreatment.TLR4,NF-кB,and TNF-αexpression in peripheral blood of ISSHL patients and healthy control subjects was assessed by ELISA before and after treatment.Results TLR4,NF-κB,and TNF-αlevels were upregulated in ISSHL patients relative to healthy control subjects;the levels were decreased following treatment and were lower in the HBO group than that in the medicine group post-treatment(P<0.05 and P<0.01).Conclusion HBOT alleviates hearing loss in ISSHL patients by suppressing the inflammatory response induced by TLR4 and NF-κB signaling. | LIU Xue Hua LIANG Fang JIA Xing Yuan ZHAO Lin ZHOU Yan YANG Jing | 2020 | Biomedical and Environmental Sciences2020，33，5： | 12 |
| 17 | Occurrence and Diversity of Marine Yeasts in Antarctica Environments显示文摘A total of 28 yeast strains were obtained from the sea sediment of Antarctica.According to the results of routine identi-fication and molecular characterization,the strains belonged to species of Yarrowia lipolytica,Debaryomyces hansenii,Rhodotorula slooffiae,Rhodotorula mucilaginosa,Sporidiobolus salmonicolor,Aureobasidium pullulans,Mrakia frigida and Guehomyces pullu-lans,respectively.The Antarctica yeasts have wide potential applications in biotechnology,for some of them can produce b-galactosidase and killer toxins. | ZHANG Xue HUA Mingxia SONG Chunli CHI Zhenming | 2012 | Journal of Ocean University of China2012，11，1： | 11 |
| 18 | Rapid and Accurate Sequencing of Enterovirus Genomes Using MinION Nanopore Sequencer显示文摘Objective Knowledge of an enterovirus genome sequence is very important in epidemiological investigation to identify transmission patterns and ascertain the extent of an outbreak.The MinION sequencer is increasingly used to sequence various viral pathogens in many clinical situations because of its long reads,portability,real-time accessibility of sequenced data,and very low initial costs.However,information is lacking on MinION sequencing of enterovirus genomes.Methods In this proof-of-concept study using Enterovirus 71(EV71) and Coxsackievirus A16(CA16) strains as examples,we established an amplicon-based whole genome sequencing method using MinION.We explored the accuracy,minimum sequencing time,discrimination and high-throughput sequencing ability of MinION,and compared its performance with Sanger sequencing.Results Within the first minute(min) of sequencing,the accuracy of MinION was 98.5% for the single EV71 strain and 94.12%-97.33% for 10 genetically-related CA16 strains.In as little as 14 min,99% identity was reached for the single EV71 strain,and in 17 min(on average),99% identity was achieved for 10 CA16 strains in a single run.Conclusion MinION is suitable for whole genome sequencing of enteroviruses with sufficient accuracy and fine discrimination and has the potential as a fast,reliable and convenient method for routine use. | WANG Ji KE Yue Hua ZHANG Yong HUANG Ke Qiang WANG Lei SHEN Xin Xin DONG Xiao Ping XU Wen Bo MA Xue Jun | 2017 | Biomedical and Environmental Sciences2017，30，10： | 11 |
| 19 | Passive-source ocean bottom seismograph(OBS) array experiment in South China Sea and data quality analyses显示文摘Long-term passive source ocean bottom seismograph(OBS) observatory is challenging due to various technical difficulties. In order to gain experience in this field, and to reveal the lithospheric structure beneath the extinct ridge in the central South China Sea(SCS), we carried out a passive source OBS array experiment, which includes 18 OBSs, in the deep portion of SCS. Here we present the instrumentation, the OBS deployment and recovery of this experiment, and more importantly, the data quality evaluated by a number of approaches. Through processing and inspecting waveforms from global, regional and local earthquakes, we find that most of recovered OBSs have good data quality with discernible main phases. The ambient noise analyses of OBS recordings show that their noise is higher than the global average, and the horizontal component is noisier than the vertical, indicating current impacts on horizontal components are more severe. In the period range of 5–10 s, there is a noise notch for the SCS OBSs, and noise levels of horizontal components are comparable to the vertical. This feature, which is not seen at OBS stations in open ocean, suggests the distant sources for double frequency microseism in this marginal sea are not significant. In addition, we successfully determined the orientations for 7 OBSs by investigating their Rayleigh wave polarizations; and we demonstrated the dispersion feature of Rayleigh waves through the frequency-time analysis. Finally, we summarized lessons learned from this experiment regarding the passive source OBS investigations in SCS. | Chenguang Liu Qingfeng Hua Yanliang Pei Ting Yang Shaohong Xia Mei Xue Ba Manh Le Da Huo Fang Liu Haibo Huang | 2014 | Chinese Science Bulletin2014，59，33： | 11 |
| 20 | Direct assimilation of satellite radiance data in GRAPES variational assimilation system显示文摘Variational method is capable of dealing with observations that have a complicated nonlinear relation with model variables representative of the atmospheric state, and so make it possible to directly assimilate such measured variables as satellite radiance, which have a nonlinear relation with the model variables. Assimilation of any type of observations requires a corresponding observation operator, which establishes a specific mapping from the space of the model state to the space of observation. This paper presents in detail how the direct assimilation of real satellite radiance data is implemented in the GRAPES-3DVar analysis system. It focuses on all the components of the observation operator for direct assimilation of real satellite radiance data, including a spatial interpolation operator that transforms variables from model grid points to observation locations, a physical transformation from model variables to observed elements with different choices of model variables, and a data quality control. Assimilation experiments, using satellite radiances such as NOAA17 AMSU-A and AMSU-B (Advanced Microwave Sounding Unit), are carried out with two different schemes. The results from these experiments can be physically understood and clearly reflect a rational effect of direct assimilation of satellite radiance data in GRAPES-3DVar analysis system. | ZHU GuoFu XUE JiShan ZHANG Hua LIU ZhiQuan ZHUANG ShiYu HUANG LiPing DONG PeiMing | 2008 | Chinese Science Bulletin2008，53，22： | 11 |
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