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| 1 | The linkage maps of Dendrobium species based on RAPD and SRAP markers显示文摘Dendrobium plants are used commonly as tonic herbs and health food in many Asian countries,especially in China.Here we report the genetic map construction of two Dendrobium species with a double pseudo-testcross strategy using random amplified polymorphic DNA(RAPD) and sequence-related amplified polymorphism(SRAP) markers.A F1 mapping population of 90 individuals was developed from a cross between D.officinale and D.hercoglossum.A total of 307 markers,including 209 RAPD and 98 SRAP,were identified and used for genetic linkage group(LG) analysis.The D.officinale linkage map consisted of 11 major linkage groups and 3 doublets,which covered 629.4 cM by a total of 62 markers with an average locus distance of 11.2 cM between two adjacent markers.The D.hercoglossum linkage map contained 112 markers mapped on 15 major and 4 minor linkage groups,spanning a total length of 1,304.6 cM with an average distance of 11.6 cM between two adjacent markers.The maps constructed in this study covered 92.7% and 82.7% of the D.hercoglossum and D.officinale genomes respectively,providing an important basis for the mapping of horticultural and medicinal traits and for the application of marker-assisted selection in Dendrobium breeding program. | Dawei Xue Shangguo Feng Hongyan Zhao Hua Jiang Bo Shen Nongnong Shi Jiangjie Lu Junjun Liu Huizhong Wang | 2010 | Journal of Genetics and Genomics2010，37，3： | 26 |
| 2 | Exosomes containing miR-21 transfer the characteristic of cisplatin resistance by targeting PTEN and PDCD4 in oral squamous cell carcinoma显示文摘 | Tao Liu Gang Chen Dawei Sun Minghui Lei Yongqiang Li Changming Zhou Xiaodong Li Wei Xue Hong Wang Chunjun Liu Jiang Xu | 2017 | Acta Biochimica et Biophysica Sinica2017，49，9： | 22 |
| 3 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 4 | Characteristics of the lunar samples returned by the Chang'E-5 mission显示文摘Forty-five years after the Apollo and Luna missions returned lunar samples,China's Chang’E-5(CE-5)mission collected new samples from the mid-latitude region in the northeastern Oceanus Procellarum of the Moon.Our study shows that 95%of CE-5 lunar soil sizes are found to be within the range of 1.40-9.35μm,while 95%of the soils by mass are within the size range of 4.84-432.27μm.The bulk density,true density and specific surface area of CE-5 soils are 1.2387 g/cm^(3),3.1952 g/cm^(3) and 0.56 m^(2)/g,respectively.Fragments from the CE-5 regolith are classified into igneous clasts(mostly basalt),agglutinate and glass.A few breccias were also found.The minerals and compositions of CE-5 soils are consistent with mare basalts and can be classified as low-Ti/low-Al/low-K type with lower rare-earth-element contents than materials rich in potassium,rare earth element and phosphorus.CE-5 soils have high FeO and low Mg index,which could represent a new class of basalt. | Chunlai Li Hao Hu Meng-Fei Yang Zhao-Yu Pei Qin Zhou Xin Ren Bin Liu Dawei Liu Xingguo Zeng Guangliang Zhang Hongbo Zhang Jianjun Liu Qiong Wang Xiangjin Deng Caijin Xiao Yonggang Yao Dingshuai Xue Wei Zuo Yan Su Weibin Wen Ziyuan Ouyang | 2022 | National Science Review2022，9，2： | 12 |
| 5 | The Low Energy X-ray telescope (LE) onboard the Insight-HXMT astronomy satellite显示文摘The Low Energy X-ray telescope(LE) is one of the three main instruments of the Insight-Hard X-ray Modulation Telescope(Insight-HXMT). It is equipped with Swept Charge Device(SCD) sensor arrays with a total geometrical area of 384 cm^2 and an energy band from 0.7 to 13 ke V. In order to evaluate the particle induced X-ray background and the cosmic X-ray background simultaneously, LE adopts collimators to define four types of Field Of Views(FOVs), i.e., 1.6°×6°, 4°×6°, 50°-60°×2°-6 oand the blocked ones which block the X-ray by an aluminum cover. LE is constituted of three detector boxes(LEDs) and an electric control box(LEB) and achieves a good energy resolution of 140 e V@5.9 ke V, an excellent time resolution of 0.98 ms, as well as an extremely low pileup(<1%@18000 cts/s). Detailed performance tests and calibration on the ground have been performed,including energy-channel relation, energy response, detection efficiency and time response. | Yong Chen WeiWei Cui Wei Li Juan Wang YuPeng Xu FangJun Lul YuSa Wang TianXiang Chen DaWei Han Wei Hu Yi Zhang Jia Huo YanJi Yang MaoShun Li Bo Lu ZiLiang Zhang TiPei Li ShuangNan Zhang ShaoLin Xiong Shu Zhang RongFeng Xue XiaoFan Zhao Yue Zhu YuXuan Zhu HongWei Liu YiJung Yang Fan Zhang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 8 |
| 6 | Recent advances in photodynamic therapy based on emerging two-dimensional layered nanomaterials显示文摘Photodynamic therapy(PDT)is a promising non-invasive therapy approach for various diseases including malignant tumor.The process of PDT involves three interrelated aspects,namely photosensitizer(PS),light source,and oxygen,among which PS is the decisive factor that determines its anticancer efficiency.There exist some defects in currently applied PDT,such as inadequate production of reactive oxygen species(ROS),poor penetration of exciting light,insufficient oxygen supply,and nonselective distribution of PS.With unique physicochemical and optical properties,two-dimensional nanomaterials(2DNMs)have aroused great interest in biomedical fields.2DNMs-based PDT is promising to significantly improve antitumor efficacy compared to conventional PDT.In this review,we will firstly introduce the underlying mechanism of PDT and how 2DNMs are absorbed and distribute inside tumor cells.After that,we will not only illustrate how 2DNMs-based PDT can enhance tumor-killing efficacy and minimize side-effects through conquering the above-mentioned defects of conventional PDT and the preparation process of 2DNMs,but also elaborate recent advances about 2DNMs-based PDT.Lastly,we will summarize the challenges and future prospects of 2DNMs-based PDT. | Xinqiang Wu Xiaofeng Jiang Taojian Fan Zhiwei Zheng Zhaoyuan Liu Yubin Chen Liangqi Cao Zhongjian Xie Dawei Zhang Jiaqi Zhao Qiwen Wang Zhenhui Huang Zhijian Chen Ping Xue Han Zhang | 2020 | Nano Research2020，13，6： | 6 |
| 7 | Research on the Construction Process and Evaluation System of Low Carbon Audit of Petroleum Enterprises显示文摘 | Zhihong Zhu Dawei Xue Baodi Liu | 2015 | Journal of US-China Public Administration2015，12，5： | 5 |
| 8 | Comparative profiling of the transcriptional response to soybean cyst nematode infection of soybean roots by deep sequencing显示文摘To gain insight into the changes in the transcriptome of soybean roots during soybean cyst nematode (SCN) infection, we conducted genome-wide gene expression profiling using serial analysis of gene expression (SAGE) combined with Solexa sequencing. More than 3 million tags were generated from the SCN-infected and uninfected roots, and 366941 and 314591 clean UniTags were obtained from SCN-infected and uninfected samples, respectively. In the SCN-infected sample, 48249 UniTags represented 18114 reference genes. In the uninfected control, 46290 UniTags represented 19323 reference genes. Comparison of tag frequencies identified 1405 genes that were expressed at greater levels in SCN-infected roots than in uninfected roots, and 1191 genes that were expressed at lower levels. Quantitative real-time PCR analyses confirmed the changes in mRNA levels observed in our sequencing analyses. A comparable number of genes were upand down-regulated in response to nematode infection, indicating that down-regulation of some genes might be essential in the plant response to nematodes. Our SAGE results showed significant changes in expression of many unreported genes involved in nematode infection. Approximately 7% of tags mapped to the antisense strand of genes, indicating widespread antisense transcription. | LI XiaoYan WANG Xue ZHANG ShaoPeng LIU DaWei DUAN YuXi DONG Wei | 2011 | Chinese Science Bulletin2011，56，18： | 5 |
| 9 | Halide Homogenization for High-Performance Blue Perovskite Electroluminescence显示文摘Metal halide perovskite light-emitting diodes(LEDs)have achieved great progress in recent years.However,bright and spectrally stable blue perovskite LED remains a significant challenge.Three-dimensional mixed-halide perovskites have potential to achieve high brightness electroluminescence,but their emission spectra are unstable as a result of halide phase separation.Here,we reveal that there is already heterogeneous distribution of halides in the as-deposited perovskite films,which can trace back to the nonuniform mixture of halides in the precursors.By simply introducing cationic surfactants to improve the homogeneity of the halides in the precursor solution,we can overcome the phase segregation issue and obtain spectrally stable single-phase blueemitting perovskites.We demonstrate efficient blue perovskite LEDs with high brightness,e.g.,luminous efficacy of 4.7,2.9,and 0.4 lmW^(-1) and luminance of over 37,000,9,300,and 1,300 cdm^(-2) for sky blue,blue,and deep blue with Commission Internationale de l’Eclairage(CIE)coordinates of(0.068,0.268),(0.091,0.165),and(0.129,0.061),respectively,suggesting real promise of perovskites for LED applications. | Lu Cheng Chang Yi Yunfang Tong Lin Zhu Gunnar Kusch Xiaoyu Wang Xinjiang Wang Tao Jiang Hao Zhang Ju Zhang Chen Xue Hong Chen Wenjie Xu Dawei Liu Rachel AOliver Richard HFriend Lijun Zhang Nana Wang Wei Huang Jianpu Wang | 2020 | Research2020，，1： | 4 |
| 10 | An infrastructure with user-centered presentation data model for integrated management of materials data and services显示文摘With scientific research in materials science becoming more data intensive and collaborative after the announcement of the Materials Genome Initiative,the need for modern data infrastructures that facilitate the sharing of materials data and analysis tools is compelling in the materials community.In this paper,we describe the challenges of developing such infrastructure and introduce an emerging architecture with high usability.We call this architecture the Materials Genome Engineering Databases(MGED).MGED provides cloud-hosted services with features to simplify the process of collecting datasets from diverse data providers,unify data representation forms with user-centered presentation data model,and accelerate data discovery with advanced search capabilities.MGED also provides a standard service management framework to enable finding and sharing of tools for analyzing and processing data.We describe MGED’s design,current status,and how MGED supports integrated management of shared data and services. | Shilong Liu Yanjing Su Haiqing Yin Dawei Zhang Jie He Haiyou Huang Xue Jiang Xuan Wang Haiyan Gong Zhuang Li Hao Xiu Jiawang Wan Xiaotong Zhang | 2021 | npj Computational Materials2021，，1： | 4 |
| 11 | Magnetically levitated/piezoelectric/triboelectric hybrid generator as a power supply for the temperature sensor显示文摘The combination of new intelligent materials and structure technology is becoming an effective way in energy havesting and self-powered sensing. In this work, we demonstrate a magnetically levitated/piezoelectric/triboelectric hybrid generator, which does not use complex structure and has high steady output performance. It includes three parts: magnetically levitated generator(MLG), piezoelectric generator(PNG), triboelectric nanogenerator(TENG). The peak power of each is 135 μW, 22 mW and3.6 mW, which are obtained at 1 MΩ, 10 kΩ and 1 kΩ, respectively. The hybrid generator can completely light up light-emitting diodes(LEDs) under the vibration frequency of 20 Hz and the vibration amplitude of 10 mm. It also can charge a 470 μF capacitor.On this basis, we have integrated the hybrid generaor as a power supply into a self-powered tempreature sensing system. The combination of three generators can not only broaden the operating range, but also increase the operating length and sensitivity.This work will extend the application of self-powered sensor in automatic production line and promote the development of industrial control technology. | ZHANG ZengXing HE Jian HAN JianQiang XU HongYan MU JiLiang WEN Tao WANG DaWei TIAN ZhuMei CHEN ZeTian XUE ChenYang | 2017 | Science China(Technological Sciences)2017，60，7： | 3 |
| 12 | Two haplotype-resolved,gap-free genome assemblies for Actinidia latifolia and Actinidia chinensis shed light on the regulatory mechanisms of vitamin C and sucrose metabolism in kiwifruit显示文摘Kiwifruit is a recently domesticated horticultural fruit crop with substantial economic and nutritional value,especially because of the high content of vitamin C in its fruit.In this study,we de novo assembled two telomere-to-telomere kiwifruit genomes from Actinidia chinensis var.‘Donghong’(DH)and Actinidia latifolia‘Kuoye’(KY),with total lengths of 608327852 and 640561626 bp for 29 chromosomes,respectively.With a burst of structural variants involving inversion,translocations,and duplications within 8.39 million years,the metabolite content of DH and KY exhibited differences in saccharides,lignans,and vitamins.A regulatory ERF098 transcription factor family has expanded in KY and Actinidia eriantha,both of which have ultra-high vitamin C content.With each assembly phased into two complete haplotypes,we identified allelic variations between two sets of haplotypes,leading to protein sequence variations in 26494 and 27773 gene loci and allele-specific expression of 4687 and 12238 homozygous gene pairs.Synchronized metabolome and transcriptome changes during DH fruit development revealed the same dynamic patterns in expression levels and metabolite contents;free fatty acids and flavonols accumulated in the early stages,but sugar substances and amino acids accumulated in the late stages.The AcSWEET9b gene that exhibits allelic dominance was further identified to positively correlate with high sucrose content in fruit.Compared with wild varieties and other Actinidia species,AcSWEET9b promoters were selected in red-flesh kiwifruits that have increased fruit sucrose content,providing a possible explanation on why red-flesh kiwifruits are sweeter.Collectively,these two gap-free kiwifruit genomes provide a valuable genetic resource for investigating domestication mechanisms and genome-based breeding of kiwifruit. | Xue Han Yilin Zhang Qiong Zhang Ni Ma Xiaoying Liu Wenjing Tao Zhiying Lou Caihong Zhong Xing Wang Deng Dawei Li Hang He | 2023 | Molecular Plant2023，16，2： | 3 |
| 13 | Physiological,Biochemical and Molecular Responses of Barley Seedlings to Aluminum Stress显示文摘Barley(Hordeum vulgare L.)is one of the most Aluminum(Al)sensitive cereal species.In this study,the physiological,biochemical,and molecular response of barley seedlings to Al treatment was examined to gain insight into Al response and tolerance mechanisms.The results showed that superoxide dismutase(SOD),peroxidase(POD)and catalase(CAT)activity were inhibited to different degrees following Al exposure.The MDA content also significantly increased with increasing Al concentrations.SRAP results indicated significant differences between Al treatments and controls in terms of SRAP profile,and the genomic template stability(GTS)decreased with increasing Al concentration and duration.These integrative results help to elucidate the underlying mechanisms that the barley response to Al toxicity. | Xiaoqin Zhang Tao Tong Bin Tian Yunxia Fang Jiangjie Pan Junjun Zheng Dawei Xue | 2019 | Phyton-International Journal of Experimental Botany2019，88，3： | 2 |
| 14 | Effects of leukemia inhibitory factor and basic fibroblast growth factor on free radicals and endogenous stem cell proliferation in a mouse model of cerebral infarction显示文摘The present study established a mouse model of cerebral infarction by middle cerebral artery occlusion,and monitored the effect of 25 μg/kg leukemia inhibitory factor and(or) basic fibroblast growth factor administration 2 hours after model establishment.Results showed that following administration,the number of endogenous neural stem cells in the infarct area significantly increased,malondialdehyde content in brain tissue homogenates significantly decreased,nitric oxide content,glutathione peroxidase and superoxide dismutase activity significantly elevated,and mouse motor function significantly improved as confirmed by the rotarod and bar grab tests.In particular,the effect of leukemia inhibitory factor in combination with basic fibroblast growth factor was the most significant.Results indicate that leukemia inhibitory factor and basic fibroblast growth factor can improve the microenvironment after cerebral infarction by altering free radical levels,improving the quantity of endogenous neural stem cells,and promoting neurological function of mice with cerebral infarction. | Weihui Huang Yadan Li Yufeng Lin Xue Ye Dawei Zang | 2012 | Neural Regeneration Research2012，7，19： | 2 |
| 15 | Synthesis of mesoporous silica materials (MCM-41) from iron ore tailings显示文摘 | Honghao Yu Xiangxin Xue Dawei Huang | 2009 | Materials Research Bulletin2009，，11： | 1 |
| 16 | Screening for in vitro metabolites of Abelmoschus manihot extract in intestinal bacteria by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry显示文摘 | Caifu Xue Shu Jiang Jianming Guo Dawei Qian Jin-ao Duan Erxin Shang | 2011 | Journal of Chromatography B2011，，32： | 1 |
| 17 | UPLC–QTOF/MS-based screening and identification of the constituents and their metabolites in rat plasma and urine after oral administration of Glechoma longituba extract显示文摘 | Shumao Ni Dawei Qian Jin-ao Duan Jianming Guo Er-xin Shang Yan Shu Caifu Xue | 2010 | Journal of Chromatography B2010，，28： | 1 |
| 18 | Degradation and Self-recovery of Polycrystalline Silicon TFT CMOS Inverters Under NBTI Stress显示文摘Degradation and self-recovery of polycrystalline Silicon(poly-Si)Thin film transistor(TFT)by using complementary metal oxide semiconductor(CMOS)inverter were investigated.Under DC stress,degradation mechanisms were clarified by comparing the Voltage transfer characteristics(VTC)of fresh and stressed inverters.It is determined that Negative bias temperature instability(NBTI)of p-TFT dominates the degradation of the inverter under zero bias DC stress.After removing the stress,the VTC continues to be degraded,because the interface trap-states and the grain boundary trapstates increase due to hydrogen species diffusion.It is found out that the VTC is shifted to its right side severely with negative bias stress of VIN.The NBTI of p-TFT is enhanced and the NBTI of n-TFT also plays a role on the degradation.When removing the negative bias stress,the self-recovery of NBTI of nTFT and the continuing degradation of NBTI of p-TFT become competing mechanisms,together controlling the VTC after-stress behavior.Consequently,the continuing degradation of NBTI of p-TFT is restrained by selfrecovery of NBTI of n-TFT. | GUO Jian YU Zhinong YAN Wei SHI Dawei XUE Jianshe XUE Wei | 2019 | Chinese Journal of Electronics2019，28，4： | 1 |
| 19 | Efficient and economical access to substituted benzothiazoles:coppercatalyzed coupling of 2-haloanilides with metal sulfides and subsequent condensation显示文摘 | MA Dawei XIE Siwei PENG Xue | 2009 | Angew Chem Int Ed2009，48，23： | 1 |
| 20 | Screening for in vitro metabolites of Abelmoschus manihot extract in intestinal bacteria by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry显示文摘 | Caifu Xue Shu Jiang Jianming Guo Dawei Qian Jin-ao Duan Erxin Shang | 2011 | Journal of Chromatography B2011，，32： | 1 |
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