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| 1 | Synthetic hexaploid wheat and its utilization for wheat genetic improvement in China显示文摘Synthetic hexaploid wheat (Triticum turgidum × Aegilops tauschii) was created to explore for novel genes from T. turgidum and Ae. tauschii that can be used for common wheat improvement. In the present paper, research advances on the utilization of synthetic hexaploid wheat for wheat genetic improvement in China are reviewed. Over 200 synthetic hexaploid wheat (SHW) accessions from the International Maize and Wheat Improvement Centre (CIMMYT) were introduced into China since 1995. Four cultivars derived from these, Chuanmai 38, Chuanmai 42, Chuanmai 43 and Chuanmai 47, have been released in China. Of these, Chuanmai 42, with large kernels and resistance to stripe rust, had the highest average yield (> 6 t/ha) among all cultivars over two years in Sichuan provincial yield trials, outyielding the commercial check cultivar Chuanmai 107 by 22.7%. Meanwhile, by either artificial chromosome doubling via colchicine treatment or spontaneous chromosome doubling via a union of unreduced gametes (2n) from T. turgidum-Ae. tauschii hybrids, new SHW lines were produced in China. Mitotic-like meiosis might be the cytological mechanism of spontaneous chromosome doubling. SHW lines with genes for spontaneous chromosome doubling may be useful for producing new SHW-alien amphidiploids and double haploid in wheat genetic improvement. | Wuyun Yang Dengcai Liu Jun Li Lianquan Zhang Huiting Wei Xiaorong Hu Youliang Zheng Zhouhu He Yuchun Zou | 2009 | Journal of Genetics and Genomics2009，36，9： | 18 |
| 2 | Spatial distribution of polychlorinated biphenyls in soil around a municipal solid waste incinerator显示文摘The impact of a typical municipal solid waste incinerator (MSWI) on polychlorinated biphenyl (PCB) concentrations in the surrounding soil was studied. Six stack gas samples were taken from the MSWI and 21 soil samples were collected from sampling sites between 300 and 1700 m from the MSWI stack. The total (∑PCB) concentrations of dioxin-like (dl) PCBs and indicator PCBs in the stack gas samples were between 3.41 and 34.3 ng/m3, and the corresponding toxic equivalents (TEQs) ranged from 4.45 to 66.9 pg WHO-TEQ/m3, with a mean of 28.6 pg WHO-TEQ/m3. A total of 2.43 g WHO-TEQ of PCBs per year was calculated to be released into the environment from MSWIs in China. The ∑PCB concentrations in the soil samples ranged from 28.0 to 264.4 pg/g, with mean and median values of 127.6 and 127.7 pg/g, respectively, while the TEQ values were between 0.020 and 0.18 pg WHO-TEQ/g, with mean and median values of 0.074 and 0.062 pg WHO-TEQ/g, respectively. Comparing this study with other studies performed around the world suggest that PCB emission from incinerators has a critical influence on PCB concentrations in the surrounding soil. An exponential function equation is proposed, which indicates a clear decline in ∑PCB concentrations with increasing distance from the stack. A contour map created using an ordinary kriging interpolation technique showed that a limited area (1250 m radius) from the stack was clearly influenced by PCB emission from the MSWI. | Wenbin Liu Haifeng Li Zhenyu Tian Huiting Xie Jicheng Hu | 2013 | Journal of Environmental Sciences2013，25，8： | 5 |
| 3 | Lacustrine Shale Oil Resource Potential of Es3L Sub-Member of Bonan Sag, Bohai Bay Basin, Eastern China显示文摘Following shale gas, shale oil has become another highlight in unconventional hydrocarbon exploration and development. A large amount of shale oil has been produced from a host of marine shale in North America in recent years. In China, lacustrine shale, as the main source rock of conventional oil and gas, should also have abundant oil retained in place. In this study, geochemical and geologic characteristics of lacustrine shale from Es_3~L sub-member in Bonan sag were characterized by using total organic carbon(TOC), Rock-Eval pyrolysis, X-ray diffraction, and ?log R method. The results show that the Es_3~L sub-member shale have TOC contents ranging from 0.5 wt.% to 9.3 wt.%, with an average of 2.9 wt.%. The organic matter is predominantly Type I kerogen, with minor amounts of Type II1 kerogen. The temperature of maximum yield of pyrolysate(Tmax) values ranges from 424 to 447 °C, with an average of 440 °C, and vitrinite reflectance(Ro%) ranges from 0.7% to 0.9%, indicating most of shales are thermally mature. The dominant minerals of Es_3~L shale in Bonan sag are carbonates(including calcite and dolomite), averaging 51.82 wt.%, and the second minerals are clay(mostly are montmorillonite-illite-mixed layer and illite) and quartz, averaging about 18 wt.%. Finally, its shale oil resources were evaluated by using the volumetric method, and the evaluation result shows that the shale oil resource is up to 5.94 billion tons, and mostly Class I resource. Therefore, the exploration of the lacustrine shale oil of Es_3~L in Bonan sag should be strengthened. | Shuangfang Lu Wei Liu Min Wang Linye Zhang Zhentao Wang Guohui Chen Dianshi Xiao Zhandong Li Huiting Hu | 2017 | Journal of Earth Science2017，28，6： | 4 |
| 4 | Effects of Jiazhu decoction in combination with cyclophosphamide on breast cancer in mice显示文摘OBJECTIVE: To investigate the therapeutic effects of Jiazhu decoction (JZD) in combination with cyclophosphamide (CTX) on the growth of breast cancer in mice and to explore the possible molecular mechanisms of action. METHODS: BALB/c mice were randomly divided into four groups of 10 (untreated model group, JZD group, CTX group, and JZD + CTX group) and subcutaneously injected with 4T1 mouse breast cancer cells. Tumors were allowed to establish for ~7 d before initiation of treatment with CTX (100 mg/kg every week by intraperitoneal injection) and/or JZD (0.015 mL of 1.65 g/mL crude drug, administered daily by gavage). The model group received equivalent volumes of vehicle on the same schedules. Tumor volumes were measured every 3 d. Mice were sacrificed after 3 weeks of treatment, and tumors were excised and subjected to RT-qPCR and western blot analysis to evaluate expression of the Wnt/β-catenin signaling pathway components β-catenin, c-Myc, and cyclin D1 at the mRNA and protein levels. RESULTS: The mean tumor volume was smaller and the growth rate was slower in the CTX and JZD + CTX groups compared with the model group (P < 0.05), and in the JZD + CTX group compared with the CTX and JZD groups (P < 0.05). Tumor growth was inhibited by 35.4% and 48.1% by CTX and JZD + CTX treatment, respectively (P < 0.001). The expression of β-catenin, c-Myc, and cyclin D1 mRNA and protein in tumors was significantly lower in mice treated with JZD or JZD + CTX compared with the untreated mice (P < 0.05), and was significantly lower in mice treated with JZD + CTX compared with either JZD or CTX alone (P < 0.05). CONCLUSION: JZD inhibited the growth of mouse breast cancer cells in vivo, possibly by reducing the expression of β-catenin, c-Myc, and cyclin D1. Combination therapy with JZD plus CTX had a more potent inhibitory effect on breast cancer growth compared with either agent alone. | Guan Huiting Xie Su Liu Shangyi Xie Qing Hou Shengkai Liu Huarong Zhang Yunjie Hu Yaqing Zhang Chenyu | 2019 | Journal of Traditional Chinese Medicine2019，39，5： | 4 |
| 5 | Exploring facile strategies for high-oxidation-state metal nitride synthesis: carbonate-assisted one-step synthesis of Ta_3N_5 films for solar water splitting显示文摘Metal nitrides are widely studied due to their outstanding physical properties, including high hardness,high thermal and chemical stability, low electrical resistivity etc. Generally, metal nitrides can be obtained from the direct reaction of metal and ammonia/nitrogen. However, some of the metal nitrides,such as Ta_3N_5, cannot be synthesized by direct nitridation of metals. To achieve Ta_3N_5, high-oxidationstate Ta precursors like Ta_2O_5, NaTaO_3, TaS_3, K_6Ta_(10.8)O_(30), Ta(N(CH_3)_2)_5 and TaCl_5 have to be employed,which is a time-consuming and laborious process with the possibility of introducing undesirable impurities. Here taking Ta_3N_5 as an example, a facile carbonate-assisted one-step nitridation method is proposed, which enables the direct synthesis of high-oxidation-state metal nitride films from metal precursors under ammonia flow. The mechanism of the nitridation process has been studied, which carbon dioxide released from carbonates decomposition reacts with metallic Ta and assists the one-step conversion of metallic Ta to Ta_3N_5. The as-prepared Ta_3N_5 film, after modified with NiFe layered double hydroxide, exhibits promising water splitting performance and stability. This method avoids the preoxidation process of metal precursors in high-oxidation-state metal nitride synthesis, and may facilitate the direct fabrication of other important metal nitrides besides Ta_3N_5. | Tao Fang Huiting Huang Jianyong Feng Yingfei Hu Yongsheng Guo Shiying Zhang Zhaosheng Li Zhigang Zou | 2018 | Science Bulletin2018，63，21： | 3 |
| 6 | Reactive Inorganic Vapor Deposition of Perovskite Oxynitride Films for Solar Energy Conversion显示文摘The synthesis of perovskite oxynitrides,which are promising photoanode candidates for solar energy conversion,is normally accomplished by high-temperature ammonolysis of oxides and carbonate precursors,thus making the deposition of their planar films onto conductive substrates challenging.Here,we proposed a facile strategy to prepare a series of perovskite oxynitride films.Taking SrTaO_(2)N as a prototype,we prepared SrTaO_(2)N films on Ta foils under NH_(3) flow by utilizing the vaporized SrCl_(2)/SrCO_(3) eutectic salt.The SrTaO_(2)N films exhibit solar water-splitting photocurrents of 3.0 mA cm^(-2) at 1.23 V vs.RHE(reversible hydrogen electrode),which increases by 270%compared to the highest photocurrent(1.1 mA cm^(-2) at 1.23 V vs.RHE)of SrTaO_(2)N reported in the literature.This strategy may also be applied to directly prepare a series of perovskite oxynitride films on conductive substrates such as ATaO_(2)N(A=Ca,Ba)and ANbO_(2)N(A=Sr,Ba). | Tao Fang Huiting Huang Jianyong Feng Yingfei Hu Qinfeng Qian Shicheng Yan Zhentao Yu Zhaosheng Li Zhigang Zou | 2019 | Research2019，，1： | 2 |
| 7 | Self-cleaning films with high transparency based on TiO2 nanoparticles synthesized via flame combustion 显示文摘 | Wang Huiting Hu Yanjie Zhang Ling | 2010 | American ChemicalSociety2010，49，： | 1 |
| 8 | The Method and Application of Using Generalized-△LgR Technology to Predict the Organic Carbon Content of Continental Deep Source Rocks显示文摘1 Introduction△Lg R technology was widely used in source rocks(TOC)well logging evaluation as well as the most reliable way in the industry.This technology applies electrical resistivity and interval transit time curve to cauculat TOC.According to the continuous TOC content calculated form logging curvies,thickness of source rocks | HU Huiting LIU Chao LU Shuangfang | 2015 | Acta Geologica Sinica(English Edition)2015，89，A01： | 1 |
| 9 | Risk factors and clinical outcomes of incomplete endoscopic resection of small rectal neuroendocrine tumors in southern China:a 9-year data analysis显示文摘Background:The histologically complete resection(CR)rate of small rectal neuroendocrine tumors(RNETs)is unsatisfactory at the first endoscopy.Risk factors and clinical outcomes associated with incomplete resection(IR)have not been explicitly elucidated.This study aims to explore the relevant factors of IR.Methods:This retrospective study reviewed patients with small RNETs(10mm)in eight centers from January 2013 to December 2021.Clinicopathological characteristics and clinical outcomes were compared between the CR and IR groups,and the polypectomy and advanced treatment groups.Results:Of the 326 patients included,83(25.5%)were diagnosed with IR.Polypectomy(odds ratio[OR]=16.86),a central depression(OR=7.50),and treatment in the early period(OR=2.60)were closely associated with IR.Further analysis revealed that an atypical hyperemic appearance(OR=7.49)and treatment in the early period(OR=2.54)were significantly associated with the inappropriate use of polypectomy(both P<0.05).In addition,a total of 265(81.3%)were followed up with a median follow-up period of 30.9 months.No death,metastasis,or recurrence was found during the follow-up period.Conclusions:Polypectomy,a central depression,and treatment in the early period were risk factors for IR.Further,an atypical hyperemic appearance and treatment in the early period were significant predisposing factors for inappropriate choice of polypectomy.For histologically incompletely resected small RNETs,follow-up may be a safe and feasible alternative to rigorous salvage therapy. | Xiaoduan Zhuang Shaoheng Zhang Guiquan Chen Zongqi Luo Huiqin Hu Wenfeng Huang Yu Guo Yongwen Ouyang Liang Peng Qing Qing Huiting Chen Bingsheng Li Jie Chen Xinying Wang | 2023 | Gastroenterology Report2023，11，1： | 0 |
| 10 | Clinical Effects of the COVID-19 Pandemic Among the Uninfected Pregnant Women—6 PLADs,China,2019−2020显示文摘Summary What is already known about this topic?The coronavirus disease 2019(COVID-19)pandemic potentially affected prenatal care quality and maternal and fetal outcomes globally.What is added by this report?During COVID-19 pandemic period,the rates of caesarean sections(CS)and preterm birth for uninfected pregnant women increased slightly in areas that were relatively severely impacted by the pandemic in China. | Bin Wang Hang An Huanqing Hu Wei Zhao Bahabaike Jiangtulu Shuo Wang Jiamei Wang Junxi Chen Manman Long Zewu Li Yu Jin Yuhuan Li Huiting Chen Tao Xue Xiqing Li Kexin Li Wei Du Suhong Gao Jiangli Di Xiaohong Liu Rongwei Ye Zhiwen Li | 2021 | China CDC weekly2021，3，10： | 0 |
| 11 | Petroleum exploration breakthrough and geological significance in Cretaceous Yingcheng and Denglouku formations of Shuangcheng area, northern Songliao Basin, NE China显示文摘Based on drilling geological,geochemical,geophysical and production test data,the characteristics of source rocks,reservoir rocks and caprocks,as well as the process of hydrocarbon generation,trap evolution and oil accumulation of the oil-bearing assemblage composed of the Cretaceous Yingcheng Formation(K1yc)and Denglouku Formation(K1d)in the Shuangcheng area,northern Songliao Basin,NE China,were analyzed by using the research methods for petroleum systems.The source rocks mainly exist in K1yc,with the organic matters mainly originated from lower aquatic organisms and algae,and reaching the grade of high-quality source rock in terms of organic abundance.The crude oil,which is characterized by low density,high freezing point and high wax content,is believed to have generated by the K1yc source rocks.The reservoir rocks include K1d sandstones and K1yc glutenites.The mudstone in the fourth member of K1d serves as the direct caprock of the oil reservoir.The oil was generated during the period between Yaojia Formation and Nenjiang Formation,and then accumulated during the periods of Nenjiang Formation and Paleogene–Neogene.The traps evolved in three stages:the late Yingcheng Formation,the late Quantou Formation and the late Nenjiang Formation,forming structural and structural-lithologic reservoirs.It is concluded that good source-reservoir-caprock assemblage,late hydrocarbon charging,short migration distance and stable tectonic setting are favorable factors for the formation of oil reservoirs. | LIU Chao FU Xiaofei LI Yangcheng WANG Haixue SUN Lidong LU Jiamin LI Junhui SUN Youhai SHI Lidong HU Huiting YUAN Hongqi YANG Zicheng | 2023 | Petroleum Exploration and Development2023，50，1： | 0 |
| 12 | TREM-2 Drives Development of Multiple Sclerosis by Promoting Pathogenic Th17 Polarization显示文摘Multiple sclerosis(MS)is a neuroinflammatory demyelinating disease,mediated by pathogenic T helper 17(Th17)cells.However,the therapeutic effect is accompa-nied by the fluctuation of the proportion and function of Th17 cells,which prompted us to find the key regulator of Th17 differentiation in MS.Here,we demonstrated that the triggering receptor expressed on myeloid cells 2(TREM-2),a modulator of pattern recognition receptors on innate immune cells,was highly expressed on pathogenic CD4-positive T lymphocyte(CD4^(+)T)cells in both patients with MS and experimental autoimmune encephalomyelitis(EAE)mouse models.Conditional knockout of Trem-2 in CD4^(+)T cells significantly alleviated the disease activity and reduced Th17 cell infiltration,activation,differentiation,and inflammatory cytokine production and secretion in EAE mice.Furthermore,with Trem-2 knockout in vivo experiments and in vitro inhibitor assays,the TREM-2/zeta-chain associated protein kinase 70(ZAP70)/signal transducer and activator of transcription 3(STAT3)signal axis was essential for Th17 activation and differentiation in EAE progression.In conclusion,TREM-2 is a key regulator of pathogenic Th17 in EAE mice,and this sheds new light on the potential of this therapeutic target for MS. | Siying Qu Shengfeng Hu Huiting Xu Yongjian Wu Siqi Ming Xiaoxia Zhan Cheng Wang Xi Huang | 2024 | Neuroscience Bulletin2024，40，1： | 0 |
| 13 | Lead toxicity thresholds in 17 Chinese soils based on substrate-induced nitrification assay显示文摘The influence of soil properties on toxicity threshold values for Pb toward soil microbial processes is poorly recognized. The impact of leaching on the Pb threshold has not been assessed systematically. Lead toxicity was screened in 17 Chinese soils using a substrate-induced nitrification(SIN) assay under both leached and unleached conditions.The effective concentration of added Pb causing 50% inhibition(EC50) ranged from 185 to> 2515 mg/kg soil for leached soil and 130 to > 2490 mg/kg soil for unleached soil. These results represented > 13- and > 19-fold variations among leached and unleached soils,respectively. Leaching significantly reduced Pb toxicity for 70% of both alkaline and acidic soils tested, with an average leaching factor of 3.0. Soil p H and CEC were the two most useful predictors of Pb toxicity in soils, explaining over 90% of variance in the unleached EC50 value. The relationships established in the present study predicted Pb toxicity within a factor of two of measured values. These relationships between Pb toxicity and soil properties could be used to establish site-specific guidance on Pb toxicity thresholds. | Ji Li Yizong Huang Ying Hu Shulan Jin Qiongli Bao Fei Wang Meng Xiang Huiting Xie | 2016 | Journal of Environmental Sciences2016，28，6： | 0 |
| 14 | Anti-NMDAR encephalitis with seizure-like activity and hemiplegia-a case report and literature review显示文摘Background Anti-N-methyl-D-aspartate receptor(NMDAR)encephalitis accounts for the vast majority of cases of autoimmune encephalitis.Its common clinical symptoms are psychiatric symptoms,behavioral dysfunction,seizures,speech impairment,cognitive impairment,movement disorders,decreased consciousness,and autonomic instability.This report was aimed to provide evidence for anti-NMDAR encephalitis with seizure-like activity,based on the clinical presentations,brain magnetic resonance imaging(MRI),and electroencephalogram(EEG)recordings.Case presentation We report a 11-year-old girl who suffered epigastric pain after vigorous physical activity.She felt weakness of the muscles.She had syncope only once and urinary incontinence on the way to the hospital and vomited at the arrival.The entire procedure lasted approximately 15 min.The next night she had recurrent headache attacks along with irritability,like someone“tapping”to the right occipital region.She experienced numbness in the left upper limbs and shallowing of the frontal lines on the left side.Holter monitoring showed normal findings,but brain MRI,EEG recording,and cerebrospinal fluid(CSF)antibody testing showed abnormal results.The patient was finally diagnosed with anti-NMDAR encephalitis.After treatment with glucocorticoids and acyclovir,she fully recovered and was discharged from the hospital.Conclusions Although the patient presented with pain and impaired limb movements,she did not have respiratory or(and)circulatory failure,and the symptoms entirely resolved.Early accurate diagnosis and timely treatment are essential for patients with anti-NMDAR encephalitis. | Junjie Hu Cailei Zhao Xia Zhao Yu Fang Huiting Zhang Dezhi Cao Jianxiang Liao | 2022 | Acta Epileptologica2022，5，4： | 0 |
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