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| 1 | The relevance of serum albumin among elderly patients with acute decompensated heart failure显示文摘Objective To assess the prognostic utility of serum albumin among elderly patients admitted for acute decompensated heart failure(ADHF)in terms of all-cause mortality and also to identify the predictors of hypoalbuminemia.Methods Retrospective cohort study of 119 elderly patients admitted for ADHF.Elderly patients were defined as patients over the age of 65 years.The patients were followed up for approximately 11 years.Patients with advanced renal failure,liver disease not due to HF,cancer and other causes of low life expectancy were excluded.Hypoalbuminemia was defined as serum albumin≤2.9 g/dL.Results The study was made up of 65 females and 54 males with age ranging from 65 to 96 years.Of the 119 elderly patients with ADHF,there were 26 deaths.A significantly higher proportion of patients in the mortality group had an admission serum albumin level of≤2.9 g/dL than those surviving(P=0.011).After Cox’s logistic regression,low albumin(P=0.016),elevated direct bilirubin(P=0.03),age greater than 85(P=0.008),lack of use of beta blockers(P=0.0001)and left ventricular ejection fraction less than 35%(P=0.005)increased the risk of death.Elevated serum creatinine(P=0.0357)was the only predictor of hypoalbuminemia following multiple linear regression.Conclusions Hypoalbuminemia may be an unrecognized marker of death in elderly patients with ADHF. | Tuoyo O Mene-Afejuku Ela-Anamaria Moisa Adedoyin Akinlonu Carissa Dumancas Shushan Veranyan Jose A Perez Peggy Salazar Shobhana Chaudhari Gerald Pekler Savi Mushiyev Ferdinand Visco | 2019 | Journal of Geriatric Cardiology2019，16，7： | 10 |
| 2 | Reduced Exposure to Calcineurin Inhibitors Early After Liver Transplantation Prevents Recurrence of Hepatocellular Carcinoma显示文摘 | Manuel Rodríguez-Perálvarez Emmanuel Tsochatzis María Carmen Naveas Giulia Pieri Carmen García-Caparrós James O’Beirne Antonio Poyato-González Gustavo Ferrín-Sánchez Jose Luis Montero-álvarez David Patch Douglas Thorburn Javier Brice?o Manuel De la Mata A | 2013 | Journal of Hepatology2013，，： | 5 |
| 3 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 4 | Kvalualion of facial m'rve fol-lowing open redutrlion and internal fixation of subcondylar fracturethrough retromandibular transparotid approach显示文摘 | Hhutia O Kumar L Jose A | 2014 | Br J Oral Max-illofac Surg2014，52，3： | 1 |
| 5 | WebTurning:Teleoperation of a CNC turning center through the Internet显示文摘 | Alberto Jose ' A' lvares Joa~o Carlos Esp' ndola Ferreira | 2006 | Journal of Materials Procesing Technology2006，，179： | 1 |
| 6 | Determination of selenium in nutritionally relevant foods by graphite atiomic absorption spectrometry using arsenic as internal standard显示文摘 | Adriana P O Jose A G N Joaquim A N | 2005 | Food Chemistry2005，93，2： | 1 |
| 7 | Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans显示文摘 | Rhee Eugene P Cheng Susan Larson Martin G Walford Geoffrey A Lewis Gregory D McCabe Elizabeth Yang Elaine Farrell Laurie Fox Caroline S O’Donnell Christopher J Carr Steven A Vasan Ramachandran S Florez Jose C Clish Clary B Wang Thomas J Ger | 2011 | Journal of Clinical Investigation2011，，4： | 1 |
| 8 | Reducing the error in phasor estimates from phasortets in fault voltage and current signals显示文摘 | Jose A Serna O | 2007 | IEEE Transactions on lnstrumentationandMeasurenment2007，56，3： | 1 |
| 9 | Evaluating the Polyphenol Profile in Three Segregating Grape ( Vitis vinifera L.) Populations显示文摘 | Alberto Hernández-Jiménez Rocío Gil-Mu?oz Yolanda Ruiz-García Jose María López-Roca Adrián Martinez-Cutillas Encarna Gómez-Plaza Shixin Deng | 2013 | <journal-title>Journal of Analytical Methods in Chemistry2013，，： | 1 |
| 10 | Solid cross-flow into the spout and parti- cle trajectories in conical spouted beds 显示文摘 | SAN JOSE M J MARTIN O ALVAREZ S IZQUIERDO M A BILBAO J | 1998 | Chemical Engineering Science1998，53，20： | 1 |
| 11 | Positron-emission tomography with fluorine-18-fluoro-2-deoxy-D-glucose for gallbladder cancer diagnosis显示文摘 | Antonio Rodríguez-Fernández Manuel Gómez-Río José Manuel Llamas-Elvira Simeón Ortega-Lozano Jose Antonio Ferrón-Orihuela Jose Manuel Ramia-Angel Alfonso Mansilla-Roselló María Dolores Martínez-del-Valle Carlos Ramos-Font | 2004 | The American Journal of Surgery2004，，2： | 1 |
| 12 | Oil absorption of talc minerals and dispersant demand of talc mineral non-aqueous dispersions as a function of talc content: A surface chemistry approach 显示文摘 | HERLEY C JOSEE A O ZAPATA J L | 2007 | Colloids and Surfaces A : Physicochem Eng Aspects2007，299，123： | 1 |
| 13 | Effect of superoxide dismutase from bovine eryth - rocytes on different activity parameters in adjuvant - induced arthritis 显示文摘 | Adolfo G G Jorge H A Jose L O | 1999 | Archives of Medical Research1999，30，2： | 1 |
| 14 | Molecular characterization of pestiviruses isolated from bovines in Chile显示文摘 | Jose P L Mara O C M A | 2006 | Vet Microbiol2006，115，： | 1 |
| 15 | Enhancement of Nasal Absorption of Insulin Using Chitosan Nanoparticles显示文摘 | Rocío Fernández-Urrusuno Pilar Calvo Carmen Remu?án-López Jose Luis Vila-Jato María José Alonso | 1999 | Pharmaceutical Research1999，，10： | 1 |
| 16 | Taylor-Kalman- Fourier filters for instantaneous oscillating phasor and harmonic estimates 显示文摘 | JOSE A D L O S JOHNNY R M | 2012 | IEEE Transactions on Instrumentation and Measurement2012，61，4： | 1 |
| 17 | Circulating levels and hepatic expression of molecular mediators of atherosclerosis in nonalcoholic fatty liver disease显示文摘 | Silvia Sookoian Gustavo O. Casta?o Adriana L. Burgue?o María Soledad Rosselli Tomas Fernández Gianotti Pablo Mallardi Julio San Martino Carlos Jose Pirola | 2009 | Atherosclerosis2009，，2： | 1 |
| 18 | An adapter ligation-mediated PCR method for high-throughput mapping of T-DNA inserts in the Arabidopsis genome显示文摘 | Ronan C O Jose M A Christopher J K | 2007 | Nature Protocols2007，2，11： | 1 |
| 19 | Complete destruction of pnitrophenol in aqueous medium by electro-Fenton method显示文摘 | Mehmet A O Jose P Pascal C | 2000 | Environ Sci Technol2000，34，： | 1 |
| 20 | The use of RAPD markers in the genetic analysis of the plant pathogenic fungus Cladosporium fulvum 显示文摘 | Jose A Andrew P H Richard P O | 1994 | Current Genetics1994，25，： | 1 |
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