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| 1 | Indicators of prognosis after liver transplantation in Chinese hepatocellular carcinoma patients显示文摘AIM: To identify prognostic factors of patients with hepatocellular carcinoma (HCC), who were treated by orthotopic liver transplantation (OLT). METHODS: From January 2000 to October 2006, 165 patients with HCC underwent OLT. Various clinicopathological risk factors for actuarial and recurrence-free survival were identified using the Kaplan-Meier method with the log-rank test. The Cox proportional hazards model was used to identify independently predictive factors for actuarial and recurrence-free survival, which were used to propose new selection criteria. We compared the outcome of the subgroup patients meeting different criteria. Survival analysis was performed using the Kaplan-Meier method with the log-rank test. RESULTS: The median follow-up was 13.0 mo (2.8-69.5 mo). Overall, 1-, 2-, 3-and 5-year actuarial survival was 73.3%, 45.6%, 35.4% and 32.1%, respectively. One-, 2-, 3-and 5-year overall recurrencefree survival was 67.0%, 44.3%, 34.5% and 34.5%, respectively. In univariate analysis, number of tumors, total tumor size, lobar distribution, differentiation, macrovascular invasion, microvascular invasion, capsulationof the tumor, and lymph node metastasis were found to be associated significantly with actuarial and tumor-free survival. By means of using the multivariate Cox proportional hazards model, total tumor size and macrovas-cular invasion were found to be independent predictors of actuarial and tumor-free survival. When the selection criteria were expanded into the proposed criteria, there was no significant difference in 1-, 2-, 3-and 5-year actuarial and tumor-free survival of the 49 patients who met the proposed criteria (97.6%, 82.8%, 82.8% and 82.8%, and 90.7%, 82.8%, 68.8% and 68.8%, respectively) compared with that of patients who met the Milan or University of California, San Francisco (UCSF) criteria. CONCLUSION: Macrovascular invasion and total tumor diameter are the strongest prognostic factors. The proposed criteria do not adversely affect the outcome of liver transplantation for HCC, compared with the Milan or UCSF criteria. | Jin Li Lu-Nan Yan Jan Yang Zhe-Yu Chen Bo Li Yong Zeng Tian-Fu Wen Ji-Chun Zhao Wen-Tao Wang Jia-Yin Yang Ming-Qing Xu Yu-Kui Ma | 2009 | World Journal of Gastroenterology2009，15，33： | 37 |
| 2 | Synthesis of Porous NiO Nanocrystals with Controllable Surface Area and Their Application as Supercapacitor Electrodes显示文摘We report a facile way to grow various porous NiO nanostructures including nanoslices,nanoplates,and nanocolumns,which show a structure-dependence in their specific charge capacitances.The formation of controllable porosity is due to the dehydration and re-crystallization of β-Ni(OH)_(2) nanoplates synthesized by a hydrothermal process.Thermogravimetric analysis shows that the decomposition temperature of the β-Ni(OH)_(2) nanostructures is related to their morphology.In electrochemical tests,the porous NiO nanostructures show stable cycling performance with retention of specific capacitance over 1000 cycles.Interestingly,the formation of nanocolumns by the stacking of β-Ni(OH)_(2) nanoslices/plates favors the creation of small pores in the NiO nanocrystals obtained after annealing,and the surface area is over five times larger than that of NiO nanoslices and nanoplates.Consequently,the specific capacitance of the porous NiO nanocolumns(390 F/g)is significantly higher than that of the nanoslices(176 F/g)or nanoplates(285 F/g)at a discharge current of 5 A/g.This approach provides a clear illustration of the process-structure-property relationship in nanocrystal synthesis and potentially offers strategies to enhance the performance of supercapacitor electrodes. | Xiaojun Zhang Wenhui Shi Jixin Zhu Weiyun Zhao Jan Ma Subodh Mhaisalkar Tuti Lim Maria Yanhui Yang Hua Zhang Huey Hoon Hng Qingyu Yan | 2010 | Nano Research2010，3，9： | 24 |
| 3 | Indian Ocean Capacitor Effect on Indo-Western Pacific Climate during the Summer following El Ni?o显示文摘 | Xie Shang-Ping Hu Kaiming Hafner Jan Tokinaga Hiroki Du Yan Huang Gang Sampe Takeaki | 2009 | Journal of Climate2009，，3： | 4 |
| 4 | One stop shop:backbones trees for important phytopathogenic genera:Ⅰ(2014)显示文摘Many fungi are pathogenic on plants and cause significant damage in agriculture and forestry.They are also part of the natural ecosystem and may play a role in regulating plant numbers/density.Morphological identification and analysis of plant pathogenic fungi,while important,is often hampered by the scarcity of discriminatory taxonomic characters and the endophytic or inconspicuous nature of these fungi.Molecular(DNA sequence)data for plant pathogenic fungi have emerged as key information for diagnostic and classification studies,although hampered in part by non-standard laboratory practices and analytical methods.To facilitate current and future research,this study provides phylogenetic synopses for 25 groups of plant pathogenic fungi in the Ascomycota,Basidiomycota,Mucormycotina(Fungi),and Oomycota,using recent molecular data,up-to-date names,and the latest taxonomic insights.Lineagespecific laboratory protocols together with advice on their application,as well as general observations,are also provided.We hope to maintain updated backbone trees of these fungal lineages over time and to publish them jointly as new data emerge.Researchers of plant pathogenic fungi not covered by the present study are invited to join this future effort.Bipolaris,Botryosphaeriaceae,Botryosphaeria,Botrytis,Choanephora,Colletotrichum,Curvularia,Diaporthe,Diplodia,Dothiorella,Fusarium,Gilbertella,Lasiodiplodia,Mucor,Neofusicoccum,Pestalotiopsis,Phyllosticta,Phytophthora,Puccinia,Pyrenophora,Pythium,Rhizopus,Stagonosporopsis,Ustilago and Verticillium are dealt with in this paper. | Kevin D.Hyde R.Henrik Nilsson S.Aisyah Alias Hiran A.Ariyawansa Jaime E.Blair Lei Cai Arthur W.A.M.de Cock Asha J.Dissanayake Sally L.Glockling Ishani D.Goonasekara Michal Gorczak Matthias Hahn Ruvishika S.Jayawardena Jan A.L.van Kan Matthew H.Laurence C.AndréLévesque Xinghong Li Jian-Kui Liu Sajeewa S.N.Maharachchikumbura Dimuthu S.Manamgoda Frank N.Martin Eric H.C.McKenzie Alistair R.McTaggart Peter E.Mortimer Prakash V.R.Nair Julia Pawlowska Tara L.Rintoul Roger G.Shivas Christoffel F.J.Spies Brett A.Summerell Paul W.J.Taylor Razak B.Terhem Dhanushka Udayanga Niloofar Vaghefi Grit Walther Mateusz Wilk Marta Wrzosek Jian-Chu Xu JiYe Yan Nan Zhou | 2014 | Fungal Diversity2014，，4： | 3 |
| 5 | Calcium phosphate nanoparticles show an effective activation of the innate immune response in vitro and in vivo after functionalization with flagellin显示文摘For subunit vaccines,adjuvants play a key role in shaping the magnitude,persistence and form of targeted antigen-specific immune response.Flagellin is a potent immune activator by bridging innate inflammatory responses and adaptive immunity and an adjuvant candidate for clinical application.Calcium phosphate nanoparticles are efficient carriers for different biomolecules like DNA,RNA,peptides and proteins.Flagellin-functionalized calcium phosphate nanoparticles were prepared and their immunostimuiatory effect on the innate immune system,i.e.the cytokine production,was studied.They induced the production of the proinflammatory cytokines IL-8(Caco-2 cells) and IL-1β(bone marrow-derived macrophages;BMDM) in vitro and IL-6 in vivo after intraperitoneal injection in mice.The immunostimulation was more pronounced than with free flagellin. | Diana Kozlova Viktoriya Sokolova Maohua Zhong Ejuan Zhang Jingyi Yang Wei Li Yi Yang Jan Buer Astrid Maria Westendorf Matthias Epple Huimin Yan | 2014 | Virologica Sinica2014，29，1： | 3 |
| 6 | Ambulatory Arterial Stiffness Index as a Predictor of Cardiovascular Mortality in the Dublin Outcome Study显示文摘 | Eamon Dolan Lutgarde Thijs Yan Li Neil Atkins Patricia McCormack Sean McClory Eoin O’Brien Jan A. Staessen Alice V. Stanton | 2006 | Hypertension2006，，3： | 3 |
| 7 | The metagenome of the marine anammox bacterium ‘ Candidatus Scalindua profunda’ illustrates the versatility of this globally important nitrogen cycle bacterium显示文摘 | Jack van de Vossenberg Dagmar Woebken Wouter J. Maalcke Hans J. C. T. Wessels Bas E. Dutilh Boran Kartal Eva M. Janssen‐Megens Guus Roeselers Jia Yan Daan Speth Jolein Gloerich Wim Geerts Erwin van der Biezen Wendy Pluk Kees‐Jan Francoijs Lina Russ Phylli | 2012 | Environmental Microbiology2012，，5： | 1 |
| 8 | Measuring Urban Form: Is Portland Winning the War on Sprawl? 显示文摘 | YAN SONG ERRIT - JAN KNAAP | 2004 | Journal of the American Planning Association2004，70，2： | 1 |
| 9 | Error-detec-tion redundancy model and modular reduction basederror-detect algorithm 显示文摘 | YE Yu-sheng YAN Jan ZHANG Lin | 2010 | Video Engineering China2010，，34： | 1 |
| 10 | Structural Variation of Chromosomes in Autism Spectrum Disorder显示文摘 | Christian R. Marshall Abdul Noor John B. Vincent Anath C. Lionel Lars Feuk Jennifer Skaug Mary Shago Rainald Moessner Dalila Pinto Yan Ren Bhooma Thiruvahindrapduram Andreas Fiebig Stefan Schreiber Jan Friedman Cees E.J. Ketelaars Yvonne J. Vos Can Ficici | 2008 | The American Journal of Human Genetics2008，，2： | 1 |
| 11 | Template synthe- sis of hollow carbon spheres anchored on carbon nan- otubes for high rate performance supercapacitors显示文摘 | Wang Qian Yan Jan Wang Yanbo | 2013 | Car- bon2013，52，： | 1 |
| 12 | Rheology of hydrophobically modified polyacrylamide-co-poly (acrylic acid) on addition of surfactant and variation of solution pH显示文摘 | Yan Li Jan C T Kwak | 2004 | Langmuir2004，20，： | 1 |
| 13 | Light-induced structural and functional plasticity in Drosophila larval visual system显示文摘 | Yuan Q Xiang Y Yan Z Han C Jan L Y Jan Y N | | 0，，6048： | 1 |
| 14 | Has the ClOpidogrel and Metoprolol in Myocardial Infarction Trial (COMMIT) of early β-blocker use in acute coronary syndromes impacted on clinical practice in Canada? Insights from the Global Registry of Acute Coronary Events (GRACE)显示文摘 | Jeremy Edwards Shaun G. Goodman Raymond T. Yan Robert C. Welsh Jan M. Kornder J. Paul DeYoung Denis Chauret Jean-Pierre Picard Kim A. Eagle Andrew T. Yan | 2011 | American Heart Journal2011，，： | 1 |
| 15 | Land use externalities,open space preservation,and urban sprawl显示文摘 | Gerrit Jan Knaap | 2004 | Regional Science and Urban Economics2004，34，2004： | 1 |
| 16 | Fine-mapping and molecular marker development for Pi56(t), a NBS-LRR gene conferring broad-spectrum resistance to Magnaporthe oryzae in rice显示文摘 | Yan Liu Bin Liu Xiaoyuan Zhu Jianyuan Yang Alicia Bordeos Guoliang Wang Jan E. Leach Hei Leung | 2013 | Theoretical and Applied Genetics2013，，4： | 1 |
| 17 | Ambulatory Arterial Stiffness Index Derived From 24-Hour Ambulatory Blood Pressure Monitoring显示文摘 | Yan Li Ji-Guang Wang Eamon Dolan Ping-Jin Gao Hui-Feng Guo Tim Nawrot Alice V. Stanton Ding-Liang Zhu Eoin O’Brien Jan A. Staessen | 2006 | Hypertension2006，，3： | 1 |
| 18 | Ambulatory Arterial Stiffness Index as a Predictor of Cardiovascular Mortality in the Dublin Outcome Study显示文摘 | Eamon Dolan Lutgarde Thijs Yan Li Neil Atkins Patricia McCormack Sean McClory Eoin O’Brien Jan A. Staessen Alice V. Stanton | 2006 | Hypertension2006，，3： | 1 |
| 19 | Blood pressure reduction and cardiovascular prevention:An update including the 2003-2004 Secondary prevention trials显示文摘 | Staess EN Yan LI | 2005 | Hypertens Res2005，28，： | 1 |
| 20 | Examining Health of Wetlands with Multiple Ecosystem Services as Targets in China’s Coastal Regions显示文摘Coastal zones are key interconnectors of terrestrial and marine ecosystems.Due to the degradation and fragmentation of coastal wetlands,there is an urgent need to develop assessment methodology to compare the health of wetland ecosystems at different spatial scales.This will help efficiently develop and implement protections using easy-to-access ecosystem health data.This study aims to understand the spatial distribution of coastal and inland wetland health for China’s coastal regions.A Wetland Health Index(WHI)was developed to provide a basis for policy and decision making.Four utilization models—Long Term Model,Open Model,Nature Reserve Model,and Protected and Economic Model—were defined in the context of China’s coastal regions to specifically examine wetland health.Results show that the average WHI score was 63.6 with the range of 44.8–84.3 for 35 National Nature Reserves(NNRs),and the southern NNRs generally performed better than the northern NNRs.The wetlands in the southern provinces/municipalities are relatively healthier than their northern counterparts.The competent authority has slight influence on WHI scores but duration of conservation establishment does not show a clear correlation.With increasing economic activity,the differences in health conditions(WHI scores)of China’s coastal regions also increase.Gross Domestic Product(GDP)or economic intensification does not relate to WHI scores.Appropriate trade-offs between wetland management and economic development could contribute to improve health conditions,conservation and utilization of coastal and inland wetlands. | ZHOU Yangming DOU Yuehan YU Xiubo ZHANG Li HUANG Chong WANG Yuyu LI Xiaowei LI He JIA Yifei BAKKER Martha CARSJENS Gerrit Jan ZHOU Yan DUAN Houlang | 2020 | Chinese Geographical Science2020，30，4： | 1 |
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