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| 1 | Therapeutic strategies of three-dimensional stem cell spheroids and organoids for tissue repair and regeneration显示文摘Three-dimensional(3D)stem cell culture systems have attracted considerable attention as a way to better mimic the complex interactions between individual cells and the extracellular matrix(ECM)that occur in vivo.Moreover,3D cell culture systems have unique properties that help guide specific functions,growth,and processes of stem cells(e.g.,embryogenesis,morphogenesis,and organogenesis).Thus,3D stem cell culture systems that mimic in vivo environments enable basic research about various tissues and organs.In this review,we focus on the advanced therapeutic applications of stem cell-based 3D culture systems generated using different engineering techniques.Specifically,we summarize the historical advancements of 3D cell culture systems and discuss the therapeutic applications of stem cell-based spheroids and organoids,including engineering techniques for tissue repair and regeneration. | Woochan Kim Yonghyun Gwon Sunho Park Hyoseong Kim Jangho Kim | 2023 | Bioactive Materials2023，，1： | 3 |
| 2 | Photodeposited metal-semiconductor nanocomposites and their applications显示文摘While two-dimensional layered nanomaterials including transition metal oxides and transition metal dichalcogenides have been widely researched because of their unique electronic and optical properties,they still have some limitations.To overcome these limitations,transition metal oxides and transition metal dichalcogenides based nanocomposites have been developed using various methods and have exhibited superior properties.In this paper,we introduce the photodeposition method and review the photodeposition of metal nanoparticles on the surface of transition metal oxide and transition metal dichalcogenides.Their current applications are also explained,such as photocatalysis,hydrogen evolution reaction,surface enhanced Ramanscattering,etc.This approach for nanocomposites has potential for future research areas such as photocatalysis,hydrogen evolution reaction,surface enhanced Raman scattering,and other applications.This approach for nanocomposite has the potential for future research areas. | Yoonkyung Lee Eunpa Kim Yunjeong Park Jangho Kim WonHyoung Ryu Junsuk Rho Kyunghoon Kim | 2018 | Journal of Materiomics2018，4，2： | 2 |
| 3 | Biocidal polystyrene hydantoin beads 2:control of chlorine loading显示文摘 | CHEN Yongjun WORLEY S D KIM Jangho | | 0，，： | 1 |
| 4 | Classification of breeding bird communities along an urbanization gradient using an unsupervised artificial neural network显示文摘 | Jangho Lee Inn-Sil Kwak Eungkyoung Lee | 2007 | Ecological Modelling2007，203，2： | 1 |
| 5 | Synergistic effects of nanotopography and co-culture with endothelial cells on osteogenesis of mesenchymal stem cells显示文摘 | Jangho Kim Hong Nam Kim Ki-Taek Lim Yeonju Kim Shambhavi Pandey Pankaj Garg Yun-Hoon Choung Pill-Hoon Choung Kahp-Yang Suh Jong Hoon Chung | 2013 | Biomaterials2013，，30： | 1 |
| 6 | 3,4-dihydroxytoluene,a metabolite of rutin,suppresses the progression of nonalcoholic fatty liver disease in mice by inhibiting p300 histone acetyltransferase activity显示文摘3,3′,4′,5,7-Pentahydroxyflavone-3-rhamnoglucoside(rutin)is a flavonoid with a wide range of pharmacological activities.Dietary rutin is hardly absorbed because the microflora in the large intestine metabolize rutin into a variety of compounds including quercetin and phenol derivatives such as 3,4-dihydroxyphenolacetic acid(DHPAA),3,4-dihydroxytoluene(DHT),3,4-hydroxyphenylacetic acid(HPAA)and homovanillic acid(HVA).We examined the potential of rutin and its metabolites as novel histone acetyltransferase(HAT)inhibitors.DHPAA,HPAA and DHT at the concentration of 25μM significantly inhibited in vitro HAT activity with DHT having the strongest inhibitory activity.Furthermore,DHT was shown to be a highly efficient inhibitor of p300 HAT activity,which corresponded with its high degree of inhibition on intracellular lipid accumulation in HepG2 cells.Docking simulation revealed that DHT was bound to the p300 catalytic pocket,bromodomain.Drug affinity responsive target stability(DARTS)analysis further supported the possibility of direct binding between DHT and p300.In HepG2 cells,DHT concentration-dependently abrogated p300-histone binding and induced hypoacetylation of histone subunits H3K9,H3K36,H4K8 and H4K16,eventually leading to the downregulation of lipogenesis-related genes and attenuating lipid accumulation.In ob/ob mice,administration of DHT(10,20 mg/kg,iv,every other day for 6 weeks)dose-dependently improved the NAFLD pathogenic features including body weight,liver mass,fat mass,lipid accumulation in the liver,and biochemical blood parameters,accompanied by the decreased mRNA expression of lipogenic genes in the liver.Our results demonstrate that DHT,a novel p300 histone acetyltransferase inhibitor,may be a potential preventive or therapeutic agent for NAFLD. | Jangho Lee Ji-Hye Song Min-Yu Chung Jin-Hyuk Lee Tae-Gyu Nam Jae Ho Park Jin-Taek Hwang Hyo-Kyoung Choi | 2021 | Acta Pharmacologica Sinica2021，42，9： | 1 |
| 7 | 综合平衡ADAS应用中的电源要求——汽车电源管理IC必须具有高精度、高灵活性和小尺寸,满足EMI规范显示文摘得益于高级驾驶辅助系统(ADAS),汽车驾驶正在变得越来越安全。这些系统中的摄像机与传感器、成熟算法和微处理器相结合,可以在发现道路上的障碍物时提醒驾驶员、必要时帮助制动、指示盲区等。为确保正确工作,ADAS应用要求供电电源符合特定精度以及负载瞬态响应的要求。本文探讨确保汽车电池电压正确调节所需的条件,以便为恶劣环境下的ADAS摄像机、传感器和处理器有效供电。 | Warren Tsai Jangho Jeon Chintan Parikh George Chen | 2019 | 电子产品世界2019，26，3： | 1 |
| 8 | Spinal cord edema:unusual magnetic resonance imaging findings in cervical spondylosis显示文摘 | JANGHO L IZUMI K KAZUTOSHI H | 2003 | Journal of Neurosurg(Spine)2003，99，1： | 1 |
| 9 | Experimental Study on the Heat and Mass Trans- fer of Teflon-coated Tubes for the Latent Heat Recovery 显示文摘 | LEE Jangho | 2005 | Heat Transfer Engineering2005，26，2： | 1 |
| 10 | Harmonic i- ron loss analysis of electrical machines for high-speed operation considering driving condition 显示文摘 | SEO Jangho Chung Taekyung Lee Cheolgyun | 2009 | IEEE Transactions on Magnet- ics2009，45，10： | 1 |
| 11 | Experimental Study on the Heat and Mass of for the Latent Heat Recovery显示文摘 | Jangho Lee | 2005 | Heat Transfer En- gineering2005，26，2： | 1 |
| 12 | 'An Explorative Study of Korean Consumer Participation inVirtual Brand Communities in Social Network Sites' 显示文摘 | Yongjun Sung Yoojung Kim Ohyoon Kwon Jangho Moon | | Journal of Global Marketing0，2010，： | 1 |
| 13 | Experimental study on the heat and mass transfer of teflon-coated tubes for the latent heat recovery显示文摘 | Lee Jangho | 2005 | Heat Transfer Engineering2005，26，2： | 1 |
| 14 | Combinations of nerve blocks in surgery for post COVID-19 pulmonary sequelae patient:A case report and review of literature显示文摘BACKGROUND Regional anesthesia is a promising method in patients with post coronavirus disease 2019(COVID-19)pulmonary sequelae for preserving pulmonary function and preventing postoperative pulmonary complications,compared with general anesthesia.CASE SUMMARY We provided surgical anesthesia and analgesia suitable for breast surgery by performing pectoral nerve block type II(PECS-II),parasternal,and intercostobrachial nerve blocks with intravenous dexmedetomidine administration in a 61-year-old female patient with severe pulmonary sequelae after COVID-19infection.CONCLUSION Sufficient analgesia for 7 h was provided via PECS-II,parasternal,and intercostobrachial blocks perioperatively. | Yehun Jin Suzie Lee Daehyun Kim Jangho Hur Woosik Eom | 2023 | World Journal of Clinical Cases2023，11，5： | 0 |
| 15 | Giant hepatic neuroendocrine tumor显示文摘A 47-year-old female was presented with progressive abdominal distension and dyspnea for 2 years.Her height was 152.3 cm and body weight was 53.9 kg.She was completely confined to bed and could not perform any selfcare tasks.The serum total bilirubin level was 6.4 mg/dL.Radiologic imaging showed multiple hepatic tumors involving a whole liver and compressing inferior vena cava and other organs(Panel A). | Seong Hoon Kim Jangho Park | 2021 | Hepatobiliary Surgery and Nutrition2021，10，5： | 0 |
| 16 | Bioinspired magnetic cilia:from materials to applications显示文摘Microscale and nanoscale cilia are ubiquitous in natural systems where they serve diverse biological functions.Bioinspired artificial magnetic cilia have emerged as a highly promising technology with vast potential applications,ranging from soft robotics to highly precise sensors.In this review,we comprehensively discuss the roles of cilia in nature and the various types of magnetic particles utilized in magnetic cilia;additionally,we explore the top-down and bottom-up fabrication techniques employed for their production.Furthermore,we examine the various applications of magnetic cilia,including their use in soft robotics,droplet and particle control systems,fluidics,optical devices,and sensors.Finally,we present our conclusions and the future outlook for magnetic cilia research and development,including the challenges that need to be overcome and the potential for further integration with emerging technologies. | Seongjin Park Geonjun Choi Minsu Kang Woochan Kim Jangho Kim Hoon Eui Jeong | 2023 | Microsystems & Nanoengineering2023，9，6： | 0 |
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