|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Eleven COVID-19 Outbreaks with Local Transmissions Caused by the Imported SARS-CoV-2 Delta VOC-China,July-August,2021显示文摘Starting from December 2019,Wuhan,China,encountered the first outbreak of coronavirus disease 2019(COVID-19)(1-2).The epidemic was successfully suppressed by strict containment so that the number of infected people was reduced to 0 on April 8,2020(3–4).After that,China experienced roughly 3 dozen outbreaks with local transmission caused by imported severe acute respiratory syndrome coronavirus 2(SARS-CoV-2). | Lei Zhou Kai Nie Hongting Zhao Xiang Zhao Bixiong Ye Ji Wang Cao Chen Hong Wang Jiangli Di Jinsong Li Chao Li Zhixiao Chen Ruiqi Ren Peihua Niu Hui Chen Tao Chen Yali Wang Lili Li Bingxue Han Ruhan A Si Chen Dan Li Dan Li Chunxia Jin Xin Zhang Jiangmei Liu Chunyu Xu Yecheng Yao Yenan Feng Zhili Li Bike Zhang Yang Song Peter Hao Yanping Zhang Hao Li Qun Li George F.Gao Guoqing Shi Wenbo Xu | 2021 | China CDC weekly2021，3，41： | 13 |
| 2 | Epidermal growth factor improves intestinal morphology by stimulating proliferation and differentiation of enterocytes and mTOR signaling pathway in weaning piglets显示文摘Epidermal growth factor(EGF) has been shown to improve piglet intestinal morphology and epithelial recovery. In an attempt to further understand the mechanisms behind these improvements, this study tested the hypothesis that dietary EGF may affect intestinal morphology by stimulating the proliferation and differentiation of enterocytes in weaning piglets. In piglets receiving200 μg kg^-1 EGF, crypt depth and villus height increased(P<0.05). Adding 400 μg kg^-1 EGF increased villus height-to-crypt depth ratio(P<0.05), but reduced crypt depth(P<0.05). Dietary supplementation with 200 μg kg^-1 EGF significantly increased the number of Ki67-positive cells(P<0.01) and tended to increase the mRNA level of proliferating cell nuclear antigen(P<0.10).However, this supplementation decreased the expression level of intestinal fatty acid-binding protein(P<0.05). Piglets fed with400 μg kg^-1 EGF had an increased mRNA level of intestinal alkaline phosphatase(P<0.05). The phosphorylation of m TOR(mammalian target of rapamycin) was observed in the 200 μg kg^-1 EGF group. These results suggest that dietary supplementation with a low level of EGF improved piglet intestinal morphology through stimulating the proliferation and differentiation of enterocytes, and the mTOR signaling pathway may partly be involved in this process. | Lixia Wang Fan Zhu Huansheng Yang Jianzhong Li Yali Li Xueqin Ding Xia Xiong Fengjie Ji Hanlin Zhou Yulong Yin | 2020 | Science China(Life Sciences)2020，63，2： | 7 |
| 3 | Viral and Antibody Kinetics of COVID-19 Patients with Different Disease Severities in Acute and Convalescent Phases:A 6-Month Follow-Up Study显示文摘Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has spread rapidly around the world,posing a major threat to human health and the economy.Currently,long-term data on viral shedding and the serum antibody responses in COVID-19 patients are still limited.Herein,we report the clinical features,viral RNA loads,and serum antibody levels in a cohort of 112 COVID-19 patients admitted to the Honghu People’s Hospital,Hubei Province,China.Overall,5.36%(6/112)of patients showed persistent viral RNA shedding(>45 days).The peak viral load was higher in the severe disease group than in the mild group(median cycle threshold value,36.4 versus 31.5;P=0.002).For most patients the disappearance of IgM antibodies occurred approximately 4–6 weeks after symptoms onset,while IgG persisted for over 194 days after the onset of symptoms,although patients showed a 46%reduction in antibodies titres against SARS-CoV-2 nucleocapsid protein compared with the acute phase.We also studied18 asymptomatic individuals with RT-qPCR confirmed SARS-CoV-2 infection together with 17 symptomatic patients,and the asymptomatic individuals were the close contacts of these symptomatic cases.Delayed IgG seroconversion and lower IgM seropositive rates were observed in asymptomatic individuals.These data indicate that higher viral loads and stronger antibody responses are related to more severe disease status in patients with SARS-CoV-2 infection,and the antibodies persisted in the recovered patient for more than 6 months so that the vaccine may provide protection against SARS-CoV-2 infection. | Xiaoyong Zhang Suwen Lu Hui Li Yi Wang Zhen Lu Zhihong Liu Qingtao Lai Yali Ji Xuan Huang Yongyin Li Jian Sun Yingsong Wu Xiaoning Xu Jinlin Hou | 2020 | Virologica Sinica2020，35，6： | 4 |
| 4 | Diagnostic value of negative enrichment and immune fluorescence in situ hybridization for intraperitoneal free cancer cells of gastric cancer显示文摘Objective:To explore the intraperitoneal free cancer cell(IFCC)detection value of negative enrichment and immune fluorescence in situ hybridization(NEimFISH)on chromosomes(CEN)8/17.Methods:To verify the reliability of NEimFISH,29 gastric cancer tumors,their adjacent tissues and greater omental tissues were tested.Our study then included 105 gastric cancer patients for IFCC.We defined patients as IFCC-positive if a signal was detected,regardless of the detailed cancer cell numbers.A comparison of clinicopathological features was conducted among IFCC groups.We also compared the diagnosis value and peritoneal recurrence predictive value among different detection methods.The comparison of IFCC number was also conducted among different groups.Results:A cutoff of 2.5 positive cells could distinguish all benign tissue samples and 97%of malignant tissue samples in our study.Compared to intestinal gastric cancer,patients with diffuse gastric cancer tended to have more IFCCs(6 vs.4,P=0.002).The IFCC counts were often higher in the lymphovascular invasion positive group than negative group(3 vs.1,P=0.022).All IFCC samples that were considered positive using conventional cytology were also found to be positive using NEimFISH.When compared to conventional cytology and paraffin pathology,NEimFISH had a higher IFCC positive rate(68.9%)and higher one-year peritoneal recurrence predictive value with area under the curve(AUC)of 0.922.Conclusions:Gastric cancer could be effectively diagnosed by NEimFISH.The IFCC number found using NEimFISH on CEN8/17 is closely associated with Lauren type and vascular invasion of cancer.NEimFISH is a reliable detection modality with a higher positive detection rate,higher one-year peritoneal recurrence predictive value and quantitative features for IFCC of gastric cancer. | Anqiang Wang Zhongwu Li Qian Wang Yali Bai Xin Ji Tao Fu Ke Ji Yanwen Xue Tingxu Han Xiaojiang Wu Ji Zhang Yingjie Yang Guobin Xu Zhaode Bu Jiafu Ji | 2019 | Chinese Journal of Cancer Research2019，31，6： | 3 |
| 5 | Comparative study of mutation spectrums ofMT-RNR1m.1555A〉G, GJB2, and SLC26A4 between familial and sporadic patients with nonsyndromic sensorineural hearing loss in Chinese Han显示文摘 | Li Qian Ji Yubin Han Bing Zong Liang Lan Lan Zhao Yali Wang Hongyang Wang Dayong Wang Qiuju | 2014 | Chinese Medical Journal2014，，18： | 3 |
| 6 | Facile Li-Al layered double hydroxide films on Al alloy for enhanced hydrophobicity, anti-biofouling and anti-corrosion performance显示文摘In this work,lithium(Li)-aluminum(Al)layered double hydroxide(LDH)films modified by 4-amino-2-((hydrazine methylene)amino)-4-oxobutanoic acid(denoted as AOA acid)and/or 1H,1H,2H,2H-perfluorooctyltriethoxysilane were prepared on 6N01 Al alloy by a facile,in-situ growth method with enhanced hydrophobicity,anti-biofouling and anti-corrosion performance.The preparation is low energy consumptive and environment friendly,relying on self-assembly at ambient temperature.The structure,molecular weight and functional groups of the synthesized AOA acid were characterized by NMR spectrometer,ESI-MS spectrometer and Fourier transform infrared(FT-IR)spectroscopy.And the compositions,structure and morphology of the films were characterized by Fourier transform infrared(FT-IR)spectroscopy,glancing-angle X-ray diffraction(GA-XRD),X-ray photoelectron spectroscopy(XPS),field emission scanning electron microscopy(FE-SEM)and energy-dispersive x-ray spectrum(EDS).Water contact angle measurements(CA)and atomic force microscopy(AFM)characterization show that the films possess a micro/nanostructure with an improved hydrophobicity.Immersion test,neutral salt tests(NSS)and electrochemical impedance spectroscopy(EIS)conducted in 3.5 wt.%NaCl solutions demonstrate the improved corrosion resistance of the films over bare Al alloy.Meanwhile,the films also possess an excellent anti-bacterial property toEscherichia coli,Bacillus subtilis and sulfate-reducing bacteria. | Ji Li Tianci Yuan Chengliang Zhou Bo Chen Yi Shuai Dawang Wu Dongchu Chen Xiaohu Luo Y.Frank Cheng Yali Liu | 2021 | Journal of Materials Science & Technology2021，，20： | 2 |
| 7 | Unimodal productivity-biodiversity relationship along the gradient of multidimensional resources across Chinese grasslands显示文摘Resources can affect plant productivity and biodiversity simultaneously and thus are key drivers of their relationships in addition to plant-plant interactions.However,most previous studies only focused on a single resource while negle cting the nature of resource multidimensionality.Here we integrated four essential resources for plant growth into a single metric of resource diversity(RD)to investigate its effects on the productivity-biodiversity relationship(PBR)across Chinese grasslands.Results showed that habitats differing in RD have different PBRs—positive in low-resource habitats,but neutral in medium-and high-resource ones—while collectively,a weak positive PBR was observe d.However,when excluding direct effects of RD on productivity and biodiversity,the PBR in high-resource habitats became negative,which leads to a unimodal instead of a positive PBR along the RD gradient.By integrating resource effects and changing plant-plant interactions into a unified framework with the RD gradient,our work contributes to uncovering underlying me chanisms for inconsistent PBRs at large scales. | Yanfen Wang Jianqing Du Zhe Pang Yali Liu Kai Xue Yann Hautier Biao Zhang Li Tang Lili Jiang Baoming Ji Xingliang Xu Jing Zhang Ronghai Hu Shutong Zhou Fang Wang Rongxiao Che Di Wang Chaoting Zhou Xiaoyong Cui Nico Eisenhauer Yanbin Hao | 2022 | National Science Review2022，9，12： | 2 |
| 8 | Submicron ion-exchange fibers of polystyrene and styrene-butadiene-styrene copolymer blends显示文摘 | FENG Shuqin SHEN Xinyuan JI Yali | 2011 | Journal of Macromolecular Science Part B:Physics2011，50，： | 1 |
| 9 | The application of a differential evolution algorithm on products structure opti- mization in coal preparation plants显示文摘 | Li Ji Yali Kuang Zhangguo Wang | 2012 | International Journal of Coal Preparation and Utilization2012，32，1： | 1 |
| 10 | Universality of Competitive Networks in Complex Networks显示文摘The paper proposes a model which helps to investigate the competitive aspect of real networks in quantitative terms. Through theoretical analysis and numerical simulations, it shows that the competitive model has the universality for a weighted network. The relation between parameters in the weighted network and the competitiveness in the competitive network is obtained by theoretical analysis. Based on the expression of the degree distribution of the competitive network, the strength and degree distributions of the weighted network can be calculated. The analytical solution reveals that the degree distribution of the weighted network is correlated with the increment and initial value of edge weights, which is verified by numerical simulations. Moreover, the evolving pattern of a clustering coefficient along with network parameters such as the size of a network, an updating coefficient, an initial weight and the competitiveness are obtained by further simulations. | GUO Jinli FAN Chao JI Yali | 2015 | Journal of Systems Science & Complexity2015，28，3： | 1 |
| 11 | A novel approach to the preparation of nano-blends of PPO/PS/PA6 显示文摘 | Ji Yali Ma Jinghong Liang Borun | 2005 | Polymer Bulletin2005，54，： | 1 |
| 12 | A novel approach to the Preparation of nanoblends of poly (2,6-dimethyl-1,4-phenylene oxlde)/polyamide 6显示文摘 | Ji Yali Li Wengang Ma Jinghong | 2005 | Macromol Rapid Commun2005，26，： | 1 |
| 13 | A comparative study of the maximum power point tracking methods for PV systems显示文摘 | LIU Yali LI Ming JI Xu | 2014 | Energy Conversion and Management2014，85，： | 1 |
| 14 | Ecological risk assessment and ecological security pattern optimization in the middle reaches of the Yellow River based on ERI+MCR model显示文摘The middle reaches of the Yellow River represent an important area for the protection and development of the Yellow River Basin.Most of the area of the river basin is within the Loess Plateau,which establishes it as a fragile ecological environment.Firstly,using high-resolution data of land use in the watershed from the past 30 years,landscape ecological risk(LER)sample units are defined and an ecological risk index(ERI)model is constructed.Kriging interpolation is used to display the LER spatial patterns,and the temporal and spatial evolution of risk is examined.Secondly,the spatial evolution of land use landscape change(LULC)is analyzed,and the correlation between land use landscape and ecological risk is discussed.Finally,Based on the LER model,a risk-based minimum cumulative resistance(MCR)model is established,and a comprehensive protection and management network system for the ecological source-corridor-node system designed.The results suggest that in the past 30 years,LER has a high spatial correlation and areas with extremely high ecological risks are concentrated in northwest and southeast areas of the region,of which the northwest area accounts for the highest proportion.Risk intensity is closely related to the spatial pattern of land use landscape.ERI values of forestland,grasslands,and unused land and farmland are low,medium,and high,respectively.The trend of risk evolution is“overall improvement and partial deterioration”.Man-made construction and exploitation is the most direct reason for the increase of local ecological risks.The high ecological-risk areas in the northwest are dominated by deserts which reduce excessive interference by human activities on the natural landscape.Recommendations are:high-quality farmland should be protected;forestland should be restored and rebuilt;repair and adjust the existing ecosystem to assist in landscape regeneration and reconstruction;utilize the overall planning vision of“mountain,water,forest,field,lake,grass,sand”to design a management project at the basin scale;adhere to problem-oriented and precise policy implementation. | YANG Lian'an LI Yali JIA Lujing JI Yongfan HU Guigui | 2023 | Journal of Geographical Sciences2023，33，4： | 0 |
| 15 | Tuning Structures and Microenvironments of Cu-Based Catalysts for Sustainable CO_(2) and CO Electroreduction显示文摘CONSPECTUS:The carbon balance has been disrupted by the widespread use of fossil fuels and subsequent excessive emissions of carbon dioxide(CO_(2)),which has become an increasingly critical environmental challenge for human society.The production and use of renewable energy sources and/or chemicals have been proposed as important strategies to reduce emissions,of which the electrochemical CO_(2)(or CO)reduction reaction(CO_(2)RR/CORR)in the aqueous systems represents a promising approach.Benefitted by the capacity of manufacturing high-value-added products(e.g.,ethylene,ethanol,formic acid,etc.)with a net-zero carbon emission,copper-based CO_(2)RR/CORR powered by sustainable electricity is regarded as a potential candidate for carbon neutrality.However,the diversity of selectivities in copper-based systems poses a great challenge to the research in this field and sets a great obstacle for future industrialization.To date,scientists have revealed that the electrocatalyst design and preparation play a significant role in achieving efficient and selective CO_(2)-to-chemical(or CO-to-chemical)conversion.Although substantial efforts have been dedicated to the catalyst preparation and corresponding electrosynthesis of sustainable chemicals from CO_(2)/CO so far,most of them are still derived from empirical or random searches,which are relatively inefficient and cost-intensive.Most of the mechanism studies have suggested that both intrinsic properties(such as electron states)and extrinsic environmental factors(such as surface energy)of a catalyst can significantly alter catalytic performance.Thus,these two topics are mainly discussed for copper-based catalyst developments in this Account.Here,we provided a concise and comprehensive introduction to the well-established strategies employed for the design of copperbased electrocatalysts for CO_(2)RR/CORR.We used several examples from our research group,as well as representative studies of other research groups in this field during the recent five years,with the perspectives of tuning local electron states,regulating alloy phases,modifying interfacial coverages,and adjusting other interfacial microenvironments(e.g.,molecule modification or surface energy).Finally,we employed the techno-economic assessment with a viewpoint on the future application of CO_(2)/CO electroreduction in manufacturing sustainable chemicals.Our study indicates that when carbon price is taken into account,the electrocatalytic CO_(2)-to-chemical conversion can be more market-competitive,and several potential value-added products including formate,methanol,ethylene,and ethanol can all make profits under optimal operating conditions.Moreover,a downstream module employing traditional chemical industrial processes(e.g.,thermal polymerization,catalytic hydrolysis,or condensation process)will also make the whole electrolysis system profitable in the future.These design principles,combined with the recent advances in the development of efficient copper-based electrocatalysts,may provide a low-cost and long-lasting catalytic system for a profitable industrial-scale CO_(2)RR in the future. | Ximeng Lv Zhengzheng Liu Chao Yang Yali Ji Gengfeng Zheng | 2023 | Accounts of Materials Research2023，4，3： | 0 |
| 16 | Multifunctional N,S-doped and methionine functionalized carbon dots for on−off−on Fe^(3+)and ascorbic acid sensing,cell imaging,and fluorescent ink applying显示文摘Fluorescent carbon dots(CDs)have been identified as potential nanosensors and attracted tremendous research interests in wide areas including anti-counterfeiting,environmental and biological sensing and imaging in considering of the attractive optical properties.In this work,we present a CDs based fluorescent sensor from polyvinylpyrrolidone,citric acid,and methionine as precursors by hydrothermal approach.The selective quantifying of Fe^(3+)and ascorbic acid(AA)are based on the fluorescent on-off-on process,in which the fluorescent quenching is induced by the coordination of the Fe^(3+)on the surface of the CDs,while the fluorescence recovery is mainly attributed to redox reaction between Fe^(3+)and AA,breaking the coordination and bringing the fluorescence back.Inspired by the good water solubility and biocompatibility,significant photostability,superior photobleaching resistance as well as high selectivity,sensitivity,and interference immunity,which are constructed mainly from the N,S-doping and methionine surface functionalization,the CDs have not only been employed as fluorescence ink in multiple anticounterfeiting printing and confidential document writing or transmitting,but also been developed as promising fluorescence sensors in solution and solid by CDs doped test strips and hydrogels for effectively monitoring and removing of Fe^(3+)and AA in environmental aqueous solution.The CDs have been also implemented as effective diagnostic candidates for imaging and tracking of Fe^(3+)and AA in living cells,accelerating the understanding of their function and importance in related biological processes for the prevention and treatment specific diseases. | Zheng Yang Tiantian Xu Shaobing Zhang Hui Li Yali Ji Xiaodan Jia Jianli Li | 2023 | Nano Research2023，16，4： | 0 |
| 17 | Atomically-dispersed catalyst by solid-liquid phase transition for CO_(2)electroreduction显示文摘The electrochemical reduction of carbon dioxide(CO_(2))to value-added fuels and chemicals provides a promising way to realize sustainable carbon recycling[1].Developing robust electrocatalysts with high activity and selectivity is critically important for efficient electrochemical CO_(2)reduction reaction(CO_(2)RR).Generally,it is challenging to achieve high efficiency and selectivity simultaneously in the CO_(2)RR due to the multi-proton/electron transfer processes and complex reaction intermediates. | Yali Ji Gengfeng Zheng | 2021 | Science China Chemistry2021，64，7： | 0 |
| 18 | Effect of Postharvest Heat Treatment on Pear Browning during Storage显示文摘The effect of postharvest heat treatment on browning of Huangguan pear was investigated. The results showed that heat treatment improved hardness and soluble solid content of stored pear fruit,postponed the improvement of MDA content and PPO activity in stored pear fruit and alleviated the reduction of SOD activity and the lowering of PG activity. To sum up,heat treatment reduces the occurrence of browning of stored pear fruit through the regulation of the changes in a series of physiological and biochemical indexes of fruit. | Tiezheng LIU Jingtao WANG Xiangmin SUO Yali FU Wenzhang JI | 2018 | Agricultural Biotechnology2018，7，1： | 0 |
| 19 | Effect of Ti content on the hydrogen storage properties of Zr_(1-x)Ti_xMn_2Ce_(0.015) alloys显示文摘The effect of Ti content on the hydrogen storage properties of Zr1-xTixMn2 Ce0.015(x = 0,0.2,0.3,0.5) alloys was studied by X-ray diffraction,scanning electron microscopy and pressure-composition(p-c) isotherm measurement.All of the alloys mainly consist of C14-type Laves and CeO2 phases.As the Ti content increases,the lattice parameters of the Laves phase decrease and the unit cell shrinks anisotropically,the total hydrogen absorption capacity decreases but the reversible hydrogen desorption capacity of the alloys increases,and the equilibrium pressure of the alloys increases but the plateau becomes sloping.The changes of hydrogen storage properties of Zr1-xTixMn2 Ce0.015 alloys are related to the differences in both atomic radius and hydrogen affinity between Ti and Zr elements. | JI Yali,LIU Xiaopeng,MI Jing,GUO Xiumei,Li Zhinian,JIANG Lijun,and WANG Shumao Energy Materials and Technology Research Department,General Research Institution for Nonferrous Metals,Beijing 100088,China | 2010 | Rare Metals2010，29，6： | 0 |
| 20 | Global trends in diabetic eye disease research from 2012 to 2021显示文摘Diabetic eye disease refers to a group of eye complications that occur in diabetic patients and include diabetic retinopathy, diabetic macular edema, diabetic cataracts, and diabetic glaucoma. However, the global epidemiology of these conditions has not been well characterized. In this study, we collected information on diabetic eye disease-related research grants from seven representative countries––the United States, China, Japan, the United Kingdom, Spain, Germany, and France––by searching for all global diabetic eye disease journal articles in the Web of Science and Pub Med databases, all global registered clinical trials in the Clinical Trials database, and new drugs approved by the United States, China, Japan, and EU agencies from 2012 to 2021. During this time period, diabetic retinopathy accounted for the vast majority(89.53%) of the 2288 government research grants that were funded to investigate diabetic eye disease, followed by diabetic macular edema(9.27%). The United States granted the most research funding for diabetic eye disease out of the seven countries assessed. The research objectives of grants focusing on diabetic retinopathy and diabetic macular edema differed by country. Additionally, the United States was dominant in terms of research output, publishing 17.53% of global papers about diabetic eye disease and receiving 22.58% of total citations. The United States and the United Kingdom led international collaborations in research into diabetic eye disease. Of the 415 clinical trials that we identified, diabetic macular edema was the major disease that was targeted for drug development(58.19%). Approximately half of the trials(49.13%) pertained to angiogenesis. However, few drugs were approved for ophthalmic(40 out of 1830;2.19%) and diabetic eye disease(3 out of 1830;0.02%) applications. Our findings show that basic and translational research related to diabetic eye disease in the past decade has not been highly active, and has yielded few new treatment methods and newly approved drugs. | Yuan Yuan Shangli Ji Yali Song Zhaodi Che Lu Xiao Shibo Tang Jia Xiao | 2024 | Neural Regeneration Research2024，19，10： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员