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| 1 | Treatment of malignant glioma using hyperthermia显示文摘Thirty pathologically diagnosed patients with grade III–IV primary or recurrent malignant glioma(tumor diameter 3–7 cm)were randomly divided into two groups.The control group underwent conventional radiotherapy and chemotherapy.In the hyperthermia group,primary cases received hyperthermia treatment,and patients with recurrent tumors were treated with hyperthermia in combination with radiotherapy and chemotherapy.Hyperthermia treatment was administered using a13.56-MHz radio frequency hyperthermia device.Electrodes were inserted into the tumor with the aid of a CT-guided stereotactic apparatus and heat was applied for 1 hour.During 3 months after hyperthermia,patients were evaluated with head CT or MRI every month.Gliomas in the hyperthermia group exhibited growth retardation or growth termination.Necrosis was evident in 80%of the heated tumor tissue and there was a decrease in tumor diameter.Our findings indicate that radio frequency hyperthermia has a beneficial effect in the treatment of malignant glioma. | Jiahang Sun Mian Guo Hengyuan Pang Jingtao Qi Jinwei Zhang Yunlong Ge | 2013 | Neural Regeneration Research2013，8，29： | 5 |
| 2 | Auto-compensation of velocity-height ratio for Chang’E-2 satellite CCD stereo camera显示文摘The TDI-CCD imaging method using auto-compensation of velocity-height ratio (VHR) was applied to Chang’E-2 satellite CCD stereo camera.Factors that influence the image quality of the camera were discussed,among which the mismatch error in VHR was found to be the main cause.An auto-compensation scheme for VHR was developed.The validity and effectiveness were proved by the on-orbit high quality images. | XUE Bin ZHAO BaoChang YANG JianFeng GAO Weit QIAO WeiDong MA XiaoLong ZHANG Bo LIU JiaHang ZHAO Wei JING Juan Juan | 2011 | Science China(Technological Sciences)2011，54，9： | 4 |
| 3 | Obtaining digital elevation data in different terrain and physiognomy regions with spaceborne InSAR and its application analysis显示文摘Synthetic Aperture Radar Interferometry (for short, InSAR) is a new kind of earth observation technology, which has obtained great development in recent ten years and has a great development potential and successful future. In this note, three typical regions with different physiognomies and terrains have been selected as study regions to extract their Digital Elevation Model (OEMs). Compared with the existing 1 : 250000 DEM and by analyzing their results, we have obtained its accuracy and applicable scopes. The results show that in the region (plains, mountains or highlands) with dry surface and sparse vegetation, because of the better correlatability of images, the DEM obtained by InSAR is evidently better than the existing 1 : 250000 DEM and the accuracy can reach 4-6m; in the thick-vegetation-covering region, correlatability between images descends and the accuracy of InSAR DEM can only reach about 30 m worse than its existing 1:250000 DEM; in the middle covering field, the accuracy of InSAR DEM | SHAN Xinjian SONG Xiaoyu LIU Jiahang WANG Changlin | 2002 | Chinese Science Bulletin2002，47，10： | 3 |
| 4 | Effective detection of sophisticated online banking fraud on extremely imbalanced data显示文摘 | Wei Wei Jinjiu Li Longbing Cao Yuming Ou Jiahang Chen | 2013 | World Wide Web2013，，4： | 1 |
| 5 | LncRNA CFAR promotes cardiac fibrosis via the miR-449a-5p/LOXL3/mTOR axis显示文摘Cardiac fibrosis is one of the crucial pathological factors in the heart,and various cardiac conditions associated with excessive fibrosis can eventually lead to heart failure.However,the exact molecular mechanism of cardiac fibrosis remains unclear.In the present study,we show that a novel lnc RNA that we named cardiac fibrosis-associated regulator(CFAR)is a profibrotic factor in the heart.CFAR was upregulated in cardiac fibrosis and its knockdown attenuated the expression of fibrotic marker genes and the proliferation of cardiac fibroblasts,thereby ameliorating cardiac fibrosis.Moreover,CFAR acted as a ce RNA sponge for mi R-449a-5p and derepressed the expression of LOXL3,which we experimentally established as a target gene of mi R-449a-5p.In contrast to CFAR,mi R-449a-5p was found to be significantly downregulated in cardiac fibrosis,and artificial knockdown of mi R-449a-5p exacerbated fibrogenesis,whereas overexpression of mi R-449a-5p impeded fibrogenesis.Furthermore,we found that LOXL3 mimicked the fibrotic factor TGF-β1 to promote cardiac fibrosis by activating m TOR.Collectively,our study established CFAR as a new profibrotic factor acting through a novel mi R-449a-5p/LOXL3/m TOR axis in the heart and therefore might be considered as a potential molecular target for the treatment of cardiac fibrosis and associated heart diseases. | Mingyu Zhang Bowen Zhang Xiaohan Wang Jiahang Song Ming Tong Zheng Dong Jiaonan Xu Meng Liu Yuan Jiang Ning Wang Ying Wang Zhimin Du Yanyan Liu Rong Zhang Chaoqian Xu | 2023 | Science China(Life Sciences)2023，66，4： | 1 |
| 6 | The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats 显示文摘 | JIAHANG SUN CHENCHENG XIE WEI LIU | 2012 | International Journal of Molecular Medicine2012，30，4： | 1 |
| 7 | Optical time-series signals classification based on data augmentation for small sample显示文摘Dear editor,The analysis of captured 1D time-series sequences has been a challenge in engineering research such as sensing for a long time.1D time series often exhibit more abstract and complex characteristics in engineering.For example,continuous or pulsed ultrasound is often used in ultrasonic detection[1]to transmit and receive energy in the medium to assess the location of damage or the degree of wear in the workpiece to be measured. | Xuezhi ZHANG Haonan SUN Junfeng JIANG Kun LIU Zeyu LI Jiahang JIN Wenxin BO Yin YU Tiegen LIU | 2022 | Science China(Information Sciences)2022，65，12： | 1 |
| 8 | Experimental study on the partial preheating combustion characteristic of Yankuang coal sludge显示文摘Coal sludge is a seriously polluted solid waste,and the rational utilization of its resources has long being an undoubtedly important research topic.This paper mainly studies the coal sludge partial preheating characteristic,combustion characteristic and the process of migration and conversion of nitrogen with preheating combustion technology.The experimental results indicate that most of the elements in the coal sludge are released during preheating,and the ratio of the fuel-N converted to the N_(2),NH_(3) and HCN are 75.5%,6.74%and 0.64%,respectively.Compared with the coal sludge,the BET surface area and cumulative pore area of preheated char are increased.The surface of preheated char is loose and porous with many fine particles,while raw coal is dense with larger particles.Meantime,the quantity of carbon defect structure,the active sites and the reactivity of preheated char are all increased.In the whole process,the NO_(x) emission is about 156 mg/m3(@6%O2),the ratio of fuel-N converted to NO_(x) was 2.98%,and the combustion efficiency is 96.5%.This experiment results will play a vital role in efficient and clean utilization of coal sludge. | Yi Zhang Jianguo Zhu Qinggang Lyu Jingzhang Liu Jiahang Zhang | 2021 | Waste Disposal and Sustainable Energy2021，3，3： | 1 |
| 9 | The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expressionfollowing kainate-induced seizures in rats显示文摘 | Jiahang Sun Chuncheng Xie Wei Liu Dunyue Lu Weidong Qiao Qi Huang Zhihui Huo Hong Shen Zhiguo Lin | 2012 | International Journal of Molecular Medicine2012，，4： | 1 |
| 10 | Optimization of Waste Gate Drive Circuit of Two-Stage Turbocharging System显示文摘A two stage turbocharging control system was proposed,in which the pressure regulator valve with a close-loop pressure adjusting function instead of a high speed on-off solenoid valve,is used as a driving mechanism of waste gate.A digital-analog(DA)conversion circuit based on pulse width modulation(PWM)generates one analog voltage signal required by the pressure regulating valve control.The principle of the DA conversion circuit was analyzed,meanwhile,the performance of the conversion circuit was improved by adopting a speed-up capacitor,which helps to increase the stability and responsiveness of the control voltage generated by the conversion circuit;the structure parameters of the circuit was optimized by simulation.After the optimization,the ripple wave of circuit output voltage was kept within16mV under the 12bit conversion accuracy,the conversion time of the circuit could be reduced to 4ms.The engine bench test show that the turbocharging boost pressure control system which adopted the circuit had a rather good stable control accuracy(the steady state within 0.8%)and dynamic response(the regulation time is less than 4s). | Fujun Zhang Jiahang Chang Tao Cui Meng Xia | 2017 | Journal of Beijing Institute of Technology2017，26，3： | 0 |
| 11 | Structure and reactions mechanism of sulfurized polyacrylonitrile as cathodes for rechargeable Li-S batteries显示文摘Sulfurized polyacrylonitrile(S@pPAN)composite provides a conductive pathway for sulfur active material at the molecular level and has already become one of the most promising cathode materials in lithium-sulfur batteries because of its outstanding electrochemical performances via novel solid-solid conversion mechanism.Although there are a great number of researches on the S@pPAN composite material,the accurate structure of S@pPAN and its redox reaction mechanism during the charge-discharge process still have not been determined.The previous research and inferences about the structure of S@pPAN and its electrochemical reaction mechanism were summarized in this review,providing a reference for the future study of lithiumsulfur batteries. | Xuan Zhang Huiyang Ma Jiqiong Liu Jiahang Chen Huichao Lu Yudai Huang Jiulin Wang | 2023 | Nano Research2023，16，6： | 0 |
| 12 | Intra-and inter-specific scaling laws of plants and animals显示文摘The allometric scaling laws of metabolism in 447 animal and 1200 plant species showed convex and concave curvatures between mass and metabolic rate,respectively.The objective of the study is to explain the difference of curvatures between animals and plants based on fractal models.Several intraspecific scaling laws were derived from an asymmetric vascular tree with the fractal dimension(i.e.,a in k^(a)_(1)+k^(a)_(2)+…-=1,where k_(i)refers to the ratio of daughter to mother diameters).Based on the intraspecific scaling laws,the allometric scaling exponent of metabolism(i.e.,an interspecific scaling law)was shown to be equal to one-third of fractal dimension.Moreover,a novel piecewise-defined function in conjunction with the intraspecific scaling laws was proposed to explain the diverse metabolic scaling in animals and plants.The intraspecific and interspecific scaling laws showed good agreement with morphometric measurements.The experimentally-validated scaling models predict the diversity of intraspecific and interspecific scaling seen in nature.To our knowledge,this is the first study to use fractal models to explain the convex and concave forms of metabolic scaling in animals and plants.The study resolves the long-term controversies to use the resource-transport network models for explanation of the allometric scaling law of metabolism. | Jiahang Li Hao Wu Ghassan S。Kassab Wenchang Tan Yunlong Huo | 2021 | Acta Mechanica Sinica2021，37，2： | 0 |
| 13 | Electrolyte design strategies towards long-term Zn metal anode for rechargeable batteries显示文摘Rechargeable Zinc(Zn)batteries exhibit great potentials as alternative energy storage devices due to their high safety,low cost,and environmental friendliness.However,the long-standing issues of low Coulombic efficiency(CE)and poor cycle stability of Zn anode,derived from dendrite,H_(2)evolution,and passivation are directly related to their thermodynamic instability in aqueous electrolyte,severely shorten the battery's cycle life.Recently reported electrolyte design strategies,which have made great progress to address Zn metal anode problems,are summarized into two categories,that is,aqueous electrolytes about cation-water interaction controlling and interface adjusting,and novel types of electrolytes towards less water,non-aqueous solvents,even no solvents.The final section shows the brief comparisons,including failure mechanisms of electrolyte exhaustion and short circuit for aqueous and nonaqueous electrolyte based full cells respectively,and possible perspectives for future research. | Ming Xu Jiahang Chen Yang Zhang Bareera Raza Chunyan Lai Jiulin Wang | 2022 | Journal of Energy Chemistry2022，31，10： | 0 |
| 14 | Excitation orthogonalized upconversion nanoprobe for instant visual detection of trinitrotoluene显示文摘Excitation-emission orthogonalized luminescent upconversion nanoparticles(OUCNPs),which can respond to changes in external stimuli accordingly,show great promise in many intelligent applications.However,the construction of such materials mostly relies on the selective absorption of Nd3+and Yb3+at different wavelengths and the long-range energy migration between the layers,resulting in complex structures and limited orthogonal luminescence intensity.Herein,we developed a relatively simple structure of OUCNPs(β-NaErF4@NaLuF4@NaYF4:20%Yb,2%Er@NaLuF4),where the fluorescence emission switches from red to green when the excitation wavelength is shifted from 808 to 980 nm.This structure exhibits high-quality,independent,and non-interfering orthogonal luminescence properties without Nd3+sensitization and long-range energy migration.As a proof of concept,we demonstrate the application of the designed OUCNPs in anti-counterfeiting.We also prepared OUCNPs@PEI(PEI=polyethylenimine)self-referencing fluorescent probes to enable quantitative analysis of trinitrotoluene(TNT)in solution with a detection limit of 3.04μM.The probes can be made into test strips for portable on-site visual detection of TNT,and can also be used to image latent fingerprints and detect explosive residues in fingerprints simultaneously.The concept proposed in this work can be extended to the visual detection of a larger range of organic and biological molecules,and is highly promising for practical applications. | Xu Li Xu Zhao Xiaoyu Xu Yang Lu Jiahang Wu Fangmeng Liu Xu Yan Peng Sun Chenguang Wang Xianggui Kong Xiaomin Liu Geyu Lu | 2023 | Nano Research2023，16，1： | 0 |
| 15 | Rock Climbing‑Inspired Electrohydrodynamic Cryoprinting of Micropatterned Porous Fiber Scaffolds with Improved MSC Therapy for Wound Healing显示文摘Impaired wound healing imposes great health risks to patients.Recently,mesenchymal stem cell(MSC)therapy has shown potential to improve the healing process,but approaches to employ MSCs in the treatment of wounds remain elusive.In this study,we reported a novel electrohydrodynamic(EHD)cyroprinting method to fabricate micropatterned fiber scaffolds with polycaprolactone(PCL)dissolved in glacial acetic acid(GAC).Cyroprinting ensured the formation of a porous struc-ture of PCL fibers by preventing the evaporation of GAC,thus increasing the surface roughness parameter Ra from 11 to 130 nm.Similar to how rough rocks facilitate easy climbing,the rough surface of fibers was able to increase the adhesion of adipose-derived MSCs(AMSCs)by providing more binding sites;therefore,the cell paracrine action of secreting growth factors and chemokines was enhanced,promoting fibroblast migration and vascular endothelial cell tube formation.In rat models with one-centimeter wound defects,enhanced MSC therapy based on porous PCL fiber scaffolds improved wound healing by augmenting scarless collagen deposition and angiogenesis and reducing proinflammatory reactions.Altogether,this study offers a new and feasible strategy to modulate the surface topography of polymeric scaffolds to strengthen MSC therapy for wound healing. | Jinjian Huang Jie Wu Jiahang Wang Mengjia Xu Jiao Jiao Yuhao Qiang Feng Zhang Zongan Li | 2023 | Advanced Fiber Materials2023，5，1： | 0 |
| 16 | Superlow Power Consumption Artificial Synapses Based on WSe2 Quantum Dots Memristor for Neuromorphic Computing显示文摘As the emerging member of zero-dimension transition metal dichalcogenide,WSe2 quantum dots(QDs)have been applied to memristors and exhibited better resistance switching characteristics and miniaturization size.However,low power consumption and high reliability are still challenges for WSe_(2) QDs-based memristors as synaptic devices. | Zhongrong Wang Wei Wang Pan Liu Gongjie Liu Jiahang Li Jianhui Zhao Zhenyu Zhou Jingjuan Wang Yifei Pei Zhen Zhao Jiaxin Li Lei Wang Zixuan Jian Yichao Wang Jianxin Guo Xiaobing Yan | 2023 | Research2023，，2： | 0 |
| 17 | Metal-free cascade boron-heteroatom addition and alkylation with diazo compounds显示文摘Transition metal-catalyzed carbene transfer reaction is one of the most notable advances for C-C bond formation reactionsduring the past decade,which has been widely employed in the preparation of C3-substituted indoles,Here,we described an efficient exa mple of catalyst-and metal-free aminobo ration of alkynes and C—C bond formation with diazo compounds to produce C3-substituted indoles,Diverse alkynyla nilines and diazo compounds ca n be utilized for this tandem transfo rmation under mild reaction conditions,re sulting in broad functional group co mpatibility.Additionally,this metal-free strategy can be extended to construct substituted benzofurans. | Jiahang Lv Binlin Zhao Ying Han Yu Yuan Zhuangzhi Shi | 2021 | Chinese Chemical Letters2021，32，2： | 0 |
| 18 | Experimental study on conversion path of sulfur in coal slime preheating combustion显示文摘In this study,coal slime was mainly utilized to conduct experiments on a 30 kW preheating combustion test rig to analyze the conversion pathway of sulfur during the experiment,aiming at reducing slime pollution,controlling sulfur emission reasonably,and providing theoretical support for the preheating combustion technology.The results showed that after the coal slime was preheated,a large number of elements were released.The maximum release rates for H and S were 94.0%and 73.3%,respectively.The released S was converted into the sulfur-containing gases like H_(2)S,COS,CS_(2),and the rest existed in the solid in the five forms of mercaptan,thiophene,sulfoxide,sulfone,and sulfate.Besides,during the combustion process,the gas was oxidized continuously and finally converted into SO2,leaving only the sulfate in the fly ash.In the preheating combustion process,26.7%of the S was released from the coal,73.3%of the S was retained in the semi-coke,and the final SO2 emission concentration of combustion was 959 ppm. | Jiahang Zhang Jianguo Zhu Qinggang Lv Yi Zhang | 2022 | Waste Disposal and Sustainable Energy2022，4，1： | 0 |
| 19 | The applications of catalytic asymmetric halocyclization in natural product synthesis显示文摘Halocyclization of olefinic substrate enables the establishment of cyclic skeletons via intramolecular halonium-induced nucleophilic addition,which has been well utilized as a practical strategy for constructing cyclic skeletons in natural product synthesis.Recently,the renaissance and rapid evolution of organocatalysis have accelerated the development of catalytic asymmetric halocyclization.In this context,natural product synthesis powered by catalytic asymmetric halocyclization has also achieved considerable progress in recent years.In some cases,these newly developed protocols enable more concise synthetic routes for accessing enantioenriched natural products.To this end,this review summarizes the applications of catalytic asymmetric halocyclization in natural product synthesis. | Jiahang Yan Zhiqiang Zhou Qiaoqiao He Guzhou Chen Hongbo Wei Weiqing Xie | 2022 | Organic Chemistry Frontiers2022，9，2： | 0 |
| 20 | Dynamic response and failure process of horizontal-layered fractured structure rock slope under strong earthquake显示文摘Rock slope with horizontal-layered fractured structure(HLFS)has high stability in its natural state.However,a strong earthquake can induce rock fissure expansion,ultimately leading to slope failure.In this study,the dynamic response,failure mode,and spectral characteristics of rock slope with HLFS under strong earthquake conditions were investigated based on the large-scale shaking table model test.On this basis,multiple sets of numerical calculation models were further established by UDEC discrete element program.Five influencing factors were considered in the parametric study of numerical simulations,including slope height,slope angle,bedding-plane spacing and secondary joint spacing as well as bedrock dip angle.The results showed that the failure process of rock slope with HLFS under earthquake action is mainly divided into four phases,i.e.,the tensile crack of the slope shoulder joints and shear dislocation at the top bedding plane,the extension of vertical joint cracks and increase of shear displacement,the formation of step-through sliding surfaces and the instability,and finally collapse of fractured rock mass.The acceleration response of slopes exhibits elevation amplification effect and surface effect.Numerical simulations indicate that the seismic stability of slopes with HLFS exhibits a negative correlation with slope height and angle,but a positive correlation with bedding-plane spacing,joint spacing,and bedrock dip angle.The results of this study can provide a reference for seismic stability evaluation of weathered rock slopes. | WANG Tong LIU Xianfeng HOU Zhaoxu XU Jiahang ZHANG Jun YUAN Shengyang JIANG Guanlu HU Jinshan | 2024 | Journal of Mountain Science2024，21，3： | 0 |
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