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| 1 | Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy显示文摘CD8^+T cell-mediated cancer clearance is often suppressed by the interaction between inhibitory molecules like PD-1 and PD-L1,an interaction acts like brakes to prevent T cell overreaction under normal conditions but is exploited by tumor cells to escape the immune surveillance.Immune checkpoint inhibitors have revolutionized cancer therapeutics by removing such brakes.Unfortunately,only a minority of cancer patients respond to immunotherapies presumably due to inadequate immunity.Antitumor immunity depends on the activation of the cGAS-STING pathway,as STING-deficient mice fail to stimulate tumor-infiltrating dendritic cells(DCs)to activate CD8^+T cells.STING agonists also enhance natural killer(NK)cells to mediate the clearance of CD8^+T cell-resistant tumors.Therefore STING agonists have been intensively sought after.We previously discovered that manganese(Mn)is indispensable for the host defense against cytosolic dsDNA by activating cGAS-STING.Here we report that Mn is also essential in innate immune sensing of tumors and enhances adaptive immune responses against tumors.Mn-insufficient mice had significantly enhanced tumor growth and metastasis,with greatly reduced tumor-infiltrating CD8^+T cells.Mechanically,Mn^2+promoted DC and macrophage maturation and tumor-specific antigen presentation,augmented CD8^+T cell differentiation,activation and NK cell activation,and increased memory CD8^+T cells.Combining Mn^2+with immune checkpoint inhibition synergistically boosted antitumor efficacies and reduced the anti-PD-1 antibody dosage required in mice.Importantly,a completed phase 1 clinical trial with the combined regimen of Mn^2+and anti-PD-1 antibody showed promising efficacy,exhibiting type I IFN induction,manageable safety and revived responses to immunotherapy in most patients with advanced metastatic solid tumors.We propose that this combination strategy warrants further clinical translation. | Mengze Lv Meixia Chen Rui Zhang Wen Zhang Chenguang Wang Yan Zhang Xiaoming Wei Yukun Guan Jiejie Liu Kaichao Feng Miao Jing Xurui Wang Yun-Cai Liu Qian Mei Weidong Han Zhengfan Jiang | 2020 | Cell Research2020，30，11： | 27 |
| 2 | Deformation behavior of non-rigid airships in wind tunnel tests显示文摘Deformation behavior of non-rigid airships in wind tunnel tests is studied by considering three factors, including internal pressure, flow velocity and angle of attack. Fiber Bragg grating strain sensors are used to measure the deformation of non-rigid airships. Wind tunnel tests in the case of different flow velocities and angles of attack are conducted. The measurement results reveal that the airship deformation is in proportion to internal pressure. For the tensile region,the airship deformation is in proportion to flow velocity. Effects of angle of attack on structural deformation are more complicated and there is no clear relationship existing between airship deformation and angle of attack. | Lingling LU Hongwei SONG Yiwei WANG Chenguang HUANG | 2019 | Chinese Journal of Aeronautics2019，32，3： | 9 |
| 3 | Review of the biological and engineering aspects of algae to fuels approach显示文摘Current biofuel production relies on limited arable lands on the earth,and is impossible to meet the biofuel demands.Oil producing algae are alternative biofuel feedstock with potential to meet the world’s ambitious goal to replace fossil fuels.This review provides an overview of the biological and engineering aspects in the production and processing technologies and recent advances in research and development in the algae to fuels approach.The article covers biology,selection and genetic modification of algae species and strains,production systems design,culture media and light management,harvest and dewatering,downstream processing,and environment and economic assessment.Despite the many advances made over several decades,commercialization of algal fuels remains challenging chiefly because of the techno-economic constraints.Technological breakthroughs in all major aspects must take place before commercial production of algal fuels becomes economically viable. | Paul Chen Min Min Yifeng Chen Liang Wang Yecong Li Qin Chen Chenguang Wang Yiqin Wan Xiaoquan Wang Yanling Cheng Shaobo Deng Kevin Hennessy Xiangyang Lin Yuhuan Liu Yingkuan Wang Blanca Martinez Roger Ruan | 2009 | International Journal of Agricultural and Biological Engineering2009，2，4： | 9 |
| 4 | Cordycepin protects renal ischemia/reperfusion injury through regulating inflammation,apoptosis,and oxidative stress显示文摘Cordycepin(3-deoxyadenosine)is a naturally occurring adenosine analog and one of the bioactive constituents isolated from Cordyceps sinensis,species of the fungal genus Cordyceps.It has traditionally been a prized Chinese folk medicine for the human well-being.However,the actions of cordycepin against renal ischemia/reperfusion injury(/R)are still unknown.In the present study,rats were subject to VR and cordycepin was intragastrically administered for seven consecutive days before surgery to investigate the effects and mechanisms of cordycepin against renal/R injury.The test results of kidney and peripheral blood samples of experimental animals showed that cordycepin significantly decreased serum blood urea nitrogen and creatinine levels and markedly attenuated cell injury.Mechanistic studies showed that cordycepin significantly regulated inflammation,apoptosis,and oxidative stress.These data provide new insights for investigating the natural product with the nephroprotective effect against I/R,which should be developed as a new therapeutic agent for the treatment of I/R in the future. | Feng Han Meng Dou Yuxiang Wang Cuixiang Xu Yang Li Xiaoming Ding Wujun Xue Jin Zheng Puxun Tian Chenguang Ding | 2020 | Acta Biochimica et Biophysica Sinica2020，52，2： | 9 |
| 5 | Compound Formula Rehmannia alleviates levodopainduced dyskinesia in Parkinson's disease显示文摘Compound Formula Rehmannia has been shown to be clinically effective in treating Parkinson's disease and levodopa-induced dyskinesia; however,the mechanisms remain unclear.In this study,we established a model of Parkinson's disease dyskinesia in rats,and treated these animals with Compound Formula Rehmannia.Compound Formula Rehmannia inhibited the increase in mRNA expression of N-methyl-D-aspartate receptor subunits 1 and 2 and excitatory amino acid neurotransmitter genes,and it inhibited the reduction in expression of γ-aminobutyric acid receptor B1,an inhibitory amino acid neurotransmitter gene,in the corpus striatum.In addition,Compound Formula Rehmannia alleviated dyskinesia symptoms in the Parkinson's disease rats.These experimental findings indicate that Compound Formula Rehmannia alleviates levodopa-induced dyskinesia in Parkinson's disease by modulating neurotransmitter signaling in the corpus striatum. | Long Teng Fang Hong Chenguang Zhang Jiancheng He Haiying Wang | 2014 | Neural Regeneration Research2014，9，4： | 8 |
| 6 | Initial corrosion behavior and mechanism of 7B04 aluminum alloy under acid immersion and salt spray environments显示文摘The initial corrosion behavior and mechanism of 7B04 aluminum alloy under acid immersion and salt spray environments(pH=3.5)are studied by Scanning Electron Microscope(SEM),optical microscope,Fourier Transform Infrared Spectroscopy(FT-IR),X-Ray Diffraction(XRD),potentiodynamic polarization,Electrochemical Impedance Spectroscopy(EIS),and Scanning Kelvin Probe(SKP).The results show that pitting corrosion occurs at the initial corrosion stage,and the potential difference between the second phase particles is the main cause of pitting.Pitting pits on different locations gradually expand and coalesce with the proceeding of corrosion.The main components of corrosion products are Al_(2)O_(3),Al(OH)_(3),and AlCl_(3),and the generation rate of the corrosion product layer under the salt spray environment is larger than that under acid immersion environment.Under both environments,the Volta potential distribution first disperses and then concentrates,while the charge transfer resistance first decreases and then increases with the corrosion time.The Volta potential gradually shifts in a positive direction,indicating that corrosion products have an inhibitory effect on corrosion.After the same corrosion time,the corrosion product layer resistance and the expectation of the Volta potential of the salt spray sample are higher than those of the immersion sample.Comparatively,the corrosion current density for the salt spray sample is significantly lower than the immersion sample,which indicates that the thicker the corrosion product layer,the stronger the inhibition of corrosion reaction. | Yangguang ZHANG Yueliang CHEN Yong ZHANG Guixue BIAN Chenguang WANG Andong WANG | 2022 | Chinese Journal of Aeronautics2022，35，1： | 8 |
| 7 | Manganese salts function as potent adjuvants显示文摘Aluminum-containing adjuvants have been used for nearly 100 years to enhance immune responses in billions of doses of vaccines.To date,only a few adjuvants have been approved for use in humans,among which aluminum-containing adjuvants are the only ones widely used.However,the medical need for potent and safe adjuvants is currently continuously increasing,especially those triggering cellular immune responses for cytotoxic T lymphocyte activation,which are urgently needed for the development of efficient virus and cancer vaccines.Manganese is an essential micronutrient required for diverse biological activities,but its functions in immunity remain undefined.We previously reported that Mn^(2+) is important in the host defense against cytosolic dsDNA by facilitating cGAS-STING activation and that Mn^(2+)alone directly activates cGAS independent of dsDNA,leading to an unconventional catalytic synthesis of 2′3′-cGAMP.Herein,we found that Mn^(2+) strongly promoted immune responses by facilitating antigen uptake,presentation,and germinal center formation via both cGAS-STING and NLRP3 activation.Accordingly,a colloidal manganese salt(Mn jelly,MnJ)was formulated to act not only as an immune potentiator but also as a delivery system to stimulate humoral and cellular immune responses,inducing antibody production and CD4^(+)/CD8^(+)T-cell proliferation and activation by either intramuscular or intranasal immunization.When administered intranasally,MnJ also worked as a mucosal adjuvant,inducing high levels of secretory IgA.MnJ showed good adjuvant effects for all tested antigens,including T cell-dependent and T cell-independent antigens,such as bacterial capsular polysaccharides,thus indicating that it is a promising adjuvant candidate. | Rui Zhang Chenguang Wang Yukun Guan Xiaoming Wei Mengyin Sha Mengran Yi Miao Jing Mengze Lv Wen Guo Jing Xu Yi Wan Xin-Ming Jia Zhengfan Jiang | 2021 | Cellular & Molecular Immunology2021，18，5： | 7 |
| 8 | Ultra-deep desulfurization by reactive adsorption desulfurization on copper-based catalysts显示文摘In this paper,a novel copper-based catalyst for FCC gasoline improving the ability of removal the sulfur and avoiding the loss of the octane number from olefin saturation by reactive adsorption desulfurization(RADS) was investigated.The series of Cu/Zn O-Al_2 O_3 catalysts were characterized by X-ray powder diffraction(XRD),N_2 adsorption analysis and temperature-programmed reduction(TPR) studies,X-ray photoelectron spectroscopy(XPS),scanning electron microscope(SEM) and transmission electron microscopy(TEM).The experiment results showed that the catalysts had an optimum desulfurization ability with copper loading 6 wt%,which the sulfur contents of product decreased less than 10 μg/g and olefin contents decreased from 16.19% to 14.14% for the long period operation.The appropriate Cu loading content could lead to the high active and low apparent activation energy(E_a).Therefore,the Cu-based catalyst may become a novel catalyst for second-generation for reactive adsorption desulfurization,which achieves the high desulfurization active and low olefins saturation to satisfy the upgrading the product. | Yaqing Liu Hongying Wang Jinchong Zhao Yunqi Liu Chenguang Liu | 2019 | Journal of Energy Chemistry2019，28，2： | 6 |
| 9 | Elevated plasma levels of selective cytokines in COVID-19 patients reflect viral load and lung injury显示文摘A recent outbreak of pneumonia in Wuhan,China was found to be caused by a 2019 novel coronavirus(2019-nCoV or SARS-CoV-2 or HCoV-19).We previously reported the clinical features of 12 patients with2019-n Co V infections in Shenzhen,China.To further understand the pathogenesis of COVID-19 and find better ways to monitor and treat the disease caused by 2019-n Co V,we measured the levels of 48 cytokines in the blood plasma of those 12 COVID-19 patients.Thirty-eight out of the 48 measured cytokines in the plasma of 2019-n Co V-infected patients were significantly elevated compared to healthy individuals.Seventeen cytokines were linked to 2019-nCoV loads.Fifteen cytokines,namely M-CSF,IL-10,IFN-α2,IL-17,IL-4,IP-10,IL-7,IL-1 ra,G-CSF,IL-12,IFN-γ,IL-1α,IL-2,HGF and PDGF-BB,were strongly associated with the lung-injury Murray score and could be used to predict the disease severity of2019-n Co V infections by calculating the area under the curve of the receiver-operating characteristics.Our results suggest that 2019-nCoV infections trigger extensive changes in a wide array of cytokines,some of which could be potential biomarkers of disease severity of 2019-n Co V infections.These findings will likely improve our understanding of the immunopathologic mechanisms of this emerging disease.Our results also suggest that modulators of cytokine responses may play a therapeutic role in combating the disease once the functions of these elevated cytokines have been characterized. | Yingxia Liu Cong Zhang Fengming Huang Yang Yang Fuxiang Wang Jing Yuan Zheng Zhang Yuhao Qin Xiaoyun Li Dandan Zhao Shunwang Li Shuguang Tan Zhaoqin Wang Jinxiu Li Chenguang Shen Jianming Li Ling Peng Weibo Wu Mengli Cao Li Xing Zhixiang Xu Li Chen Congzhao Zhou William J Liu Lei Liu Chengyu Jiang | 2020 | National Science Review2020，7，6： | 6 |
| 10 | Flavone Content and Bioactivity of Aqueous-Ethanolic Extracts of Phellinus Fruit Bodies显示文摘The flavone content of aqueous ethanolic extracts of Phellinus fruit bodies obtained from seven different locations was determined.Anti-tumor and antioxidant activities associated with the extracts were investigated in vitro using the Alamar Blue assay and a chemiluminecence-based method,respectively.Extracts of the seven Phellinus samples generated very similar HPLC profiles in qualitative terms although the areas of several peaks varied according to the sample type indicating quantitative differences in the case of some components.All the extracts,especially those of artificially cultivated Phellinus baumii fruit bodies,inhibited L1210 tumor cell proliferation and exhibited superoxide radical scavenging activity although there was no obvious correlation with flavone content. | HAO Ruixia ZHOU Shuai YANG Yan XI Junzhe LI Weiyao TANG Qingjiu WANG Chenguang | 2008 | 食用菌学报2008，15，2： | 6 |
| 11 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 12 | O,H,and Sr isotope evidence for origin and mixing processes of the Gudui geothermal system,Himalayas,China显示文摘Tho Gudui geothermal field records the highest temperature at equivalent borehole depths among the lainland hydrothermal systems in China's Mainland.Located about 150 km southeast of Lhasa City,the capital of Tibet,the Gudui geothermal field belongs to the Sangri-Cuona rift belt,also known as the Sangri-Cuona geothermal belt,and is representative of the non-volcanic geothermal systems in the Himalayas.In this study,oxygen-18 and deuterium isotope compositions as well as 87Sr/86Sr ratios of water samples collected from the Gudui geothermal field were characterized to understand the origin and mixing processes of the geothermal fluids at Gudui.Hydrogen and oxygen isotope plots show both,deep and shallow reservoirs in the Gudui geothermal field.Deep geothermal fluids are the mixing product of magmatic and infiltrating snow-melt water.Calculations show that the magma fluid component of the deep geothermal fluids account for about 21.10%-24.04%;magma fluids lay also be a contributing source of lithium.The linear relationship of the 87Sr/86Sr isotopic ratio versus the 1/Sr plot indicates that shallow geothermal fluids form from the mixing of deep geothermal fluids with cold groundwater.Using a binary mixing model with deep geothermal fluid and cold groundwater as two end-members,the nixing ratios of the latter in most surface hot springs samples were calculated to be between 5% and 10%.Combined with basic geological characteristics,hydrogen and oxygen isotope characteristics,strontium concentration,87Sr/(86)Sr ratios,and the binary mixing model,we infer the 6 th-Class Reservoirs Evolution Conceptual Model(6-CRECM) for the Gudui geothermal system.This model represents an idealized summary of the characteristics of the Gudui geothermal field based on our comprehensive understanding of the origin and mixing processes of the geothermal fluid in Gudui.This study may aid in identifying the geothermal and geochemical origin of the Gudui high-temperature hydrothermal systems in remote Tibet of China,whose potential for geothermal development and utilization is enormous and untapped. | Chenguang Wang Mianping Zheng Xuefei Zhang Enyuan Xing Jiangyi Zhang Jianhong Ren Yuan Ling | 2020 | Geoscience Frontiers2020，11，4： | 5 |
| 13 | miR-124/IRE-1α affects renal ischemia/reperfusion injury by regulating endoplasmic reticulum stress in renal tubular epithelial cells显示文摘Acute kidney injury(AKI)refers to a clinical syndrome that occurs as a result of a rapid decline in renal function caused by multiple factors.Renal ischemia/reperfusion(/R)injury is one of the main causes of AKI and has a high incidence and mortality,However,the specific pathogenesis of renal I/R injury is still unclear.In recent years,a major breakthrough has been made in the study of endoplasmic reticulum stress(ERS)-mediated apoptosis in I/R injury.It has been reported that miRNAs play protective roles in ischemic/reperfused organs,but the molecular mechanisms have not been investigated deeply.In this study,the renal VR mouse model was used to explore the roles of miR-124 in ERS and in renal I/R injury.The western blot results showed that the expression levels of ERS-related proteins IRE-1α,XBP-1,and glucose-regulated protein 78(GRP78)were significantly increased in the IVR model group when compared with those in the control group.Meanwhile,qPCR results showed that miR-124 expression was decreased in the I/R injury model,and overexpression of miR-124 using miR-124 mimics effectively reduced the expression of ERS-related proteins and alleviated renal LR injury.In addition,luciferase reporter assay was performed,and the results showed that IRE 1αand miR-124 may have direct interaction.In conclusion,our data indicated that miR-124 was a negative regulator of ERS via binding to IRE-1α,ultimately conferring its protective effect on the kidney,which demonstrates the regulatory mechanism of miR-124 in renal I/R injury and provides new ideas and methods for the prevention and treatment of renal I/R injury. | Chenguang Ding Meng Dou Yuxiang Wang Yang Li Ying Wang Jin Zheng Xiao Li Wujun Xue Xiaoming Ding Puxun Tian | 2020 | Acta Biochimica et Biophysica Sinica2020，52，2： | 4 |
| 14 | Passive control of cavitating flow around an axisymmetric projectile by using a trip bar显示文摘Quasi-periodical evolutions such as shedding and collapsing of unsteady cloud cavitating flow, induce strong pressure fluctuations, what may deteriorate maneuvering stability and corrode surfaces of underwater vehicles. This paper analyzed effects on cavitation stability of a trip bar arranged on high-speed underwater projectile. Small scale water tank experiment and large eddy simulation using the open source software Open FOAM were used, and the results agree well with each other. Results also indicate that trip bar can obstruct downstream re-entrant jet and pressure wave propagation caused by collapse, resulting in a relatively stable sheet cavity between trip bar and shoulder of projectiles. | Jian Huang Chao Yu Yiwei Wang Chang Xu Chenguang Huang | 2017 | Theoretical & Applied Mechanics Letters2017，7，4： | 4 |
| 15 | Geothermal-type Lithium Resources in Southern Xizang,China显示文摘High-temperature geothermal water has abundant lithium(Li)resources,and research on the development and utilization of geothermal-type lithium resources around the world are increasing.The Qinghai–Tibetan Plateau contains huge geothermal resources;especially,Li-rich geothermal resources in southern Xizang,southwestern China,are widely developed.The Li-rich geothermal spots in Xizang are mainly distributed on both sides and to the south of the Yarlung Zangbo suture zone.Such resources are often found in the intensely active high-temperature Li-rich geothermal fields and,compared with other Li-rich geothermal fields around the world,the Li-rich geothermal fluid in the Xizang Plateau,southern Xizang is characterized by good quality:the highest reported Li concentration is up to 239 mg/L;the Mg/Li ratio is extremely low and ranges from 0.03 to 1.48 for most of the Li-rich geothermal fluid;the Li/TDS value is relatively high and ranges from 0.25–1.14%compared to Zhabuye Li-rich salt lake(0.19%)and Salar de Uyuni(Bolivia)(0.08–0.31%).Continuous discharge has been stable for at least several decades,and some of them reach industrial grades of salt lake brine(32.74 mg/L).In addition,elements such as boron(B),caesium(Cs),and rubidium(Rb)are rich and can be comprehensively utilized.Based on still-incomplete statistics,there are at least 16 large-scale Li-rich hot springs with lithium concentration of 20 mg/L or more.The total discharge of lithium metal is about 4300 tons per year,equivalent to 25,686 tons of lithium carbonate.Drilling data has shown that the depth is promising and there is a lack of volcanism(non-volcanic geothermal system).With a background of the partial-melting lower crust caused by the collision of the Indo-Asia continent and based on a comprehensive analysis of the tectonic background of southern Xizang and previous geological,geophysical,and geothermal research,deep molten magma seems to provide a stable heat source for the high-temperature Li-rich geothermal field.The Li-rich parent geothermal fluid rushes to the surface to form hot springs along the extensively developed tectonic fault zones in southern Xizang;some of the Li-rich fluid flows in to form Li-rich salt lakes.However,most of the Li-rich geothermal fluid is remitted to seasonal rivers and has not been effectively exploited,resulting in great waste.With the continuous advance of lithium extraction technologies in Li-rich geothermal fluid,the lithium resource in geothermal water is promising as a new geothermal type of mineral deposit,which can be effectively exploited.This is the first study to undertake a longitudinal analysis on the characteristics,distribution and scale,origin and utilization prospects of Li-rich geothermal resources in southern Xizang,research that will contribute to a deeper understanding of Li-rich geothermal resources in the area and attract attention to these resources in China. | WANG Chenguang ZHENG Mianping ZHANG Xuefei WU Qian LIU Xifang REN Jianhong CHEN Shuangshuang | 2021 | Acta Geologica Sinica(English Edition)2021，95，3： | 4 |
| 16 | Selective hydrogenolysis of 5-hydroxymethylfurfural to 2,5-dimethylfuran over Co_3O_4 catalyst by controlled reduction显示文摘2,5-dimethyfuran(DMF), which is produced from 5-hydroxymethyfurfural(HMF) by hydrodeoxygenation(HDO), is a high quality fuel due to the high heating value, the high octane number and the suitable boiling point. Selective hydrogenation of HMF into liquid fuel DMF has been widely researched. In this paper, Co_3O_4 catalyst was prepared by co-precipitation and was reduced at different temperatures to form Co–CoO_x catalysts. The characterization of catalysts was tested by XRD, TEM, XPS, TPR, BET and NH3-TPD.Co–CoO_x possessed a high amount of Co metal and CoO_x acidic sites, wherein Co worked as the active hydrogenation sites and CoO_x acted as the acid promoter to facilitate the selective HDO of HMF to DMF.The synergistic effect of Co–CoO_x is the key for HDO of HMF, obtaining 83.3% of DMF yield at 170 °C, 12 h and the reduction temperature of 400 °C. This method not only saves the catalyst cost, but also promotes the utilization of biomass energy. | Dan Li Qiying Liu Changhui Zhu Haiyong Wang Chunhua Cui Chenguang Wang Longlong Ma | 2019 | Journal of Energy Chemistry2019，28，3： | 4 |
| 17 | Densification,microstructure and mechanical properties of multicomponent(TiZrHfNbTaMo)C ceramic prepared by pressureless sintering显示文摘A multicomponent(TiZrHfNbTaMo)C ceramic has been fabricated by pressureless sintering at temperatures from 2100℃to 2500℃,using an equimolar multicomponent carbide powder synthesized by carbothermal reduction as the starting material.Influence of sintering temperature on densification,microstructure and mechanical properties of the ceramics was investigated.The relative density increases with increasing sintering temperature,and a nearly fully dense sample is achieved by pressureless sintering at 2500℃.Average grain size increases from 3.7 to 15.2μm with increasing sintering temperature from 2300 to 2500℃.The(TiZrHfNbTaMo)C ceramic sintered at 2400℃exhibits a single phase fcc structure with homogeneous chemical composition,an average grain size of 7.0μm and a relative density of96.5%,while its measured hardness is 33.2 GPa at 100 mN and 23.2 GPa at 9.8 N. | Wen Zhang Lei Chen Chenguang Xu Wenyu Lu Yujin Wang Jiahu Ouyang Yu Zhou | 2021 | Journal of Materials Science & Technology2021，，13： | 4 |
| 18 | Efficient CO_2 capture on low-cost silica gel modified by polyethyleneimine显示文摘In this work,a series of polyethyleneimine(PEI) functionalized commercial silica gel were prepared by wet impregnation method and used as CO 2 sorbent.The as-prepared sorbents were characterized by N 2 adsorption,FT-IR and SEM techniques.CO 2 capture was tested in a fixed bed reactor using a simulated flue gas containing 15.1% CO 2 in a temperature range of 25-100 C.The effects of sorption temperature and amine content on CO 2 uptake of the adsorbents were investigated.The silica gel with a 30 wt% PEI loading manifested the largest CO 2 uptake of 93.4 mg CO 2 /g adsorbent(equal to 311.3 mg CO 2 /g PEI) among the tested sorbents under the conditions of 15.1%(v/v) CO 2 in N 2 at 75 C and atmospheric pressure.Moreover,it was rather low-cost.In addition,the PEI-impregnated silica gel exhibited stable adsorption-desorption behavior during 5 consecutive test cycles.These results suggest that the PEI-impregnated silica gel is a promising and cost-effective sorbent for CO 2 capture from flue gas and other stationary sources with low CO 2 concentration. | Ke Wang Hongyan Shang Lin Li Xinlong Yan Zifeng Yan Chenguang Liu Qingfang Zha | 2012 | Journal of Natural Gas Chemistry2012，21，3： | 4 |
| 19 | Light-triggered interfacial charge transfer and enhanced photodetection in CdSe/ZnS quantum dots/MoS_(2)mixed-dimensional phototransistors显示文摘Mix-dimensional van der Waals heterostructures(vdWHs)have inspired worldwide interests and efforts in the field of ad-vanced electronics and optoelectronics.The fundamental understanding of interfacial charge transfer is of vital import-ance for guiding the design of functional optoelectronic applications.In this work,type-Ⅱ0D-2D CdSe/ZnS quantum dots/MoS_(2)vdWHs are designed to study the light-triggered interfacial charge behaviors and enhanced optoelectronic performances.From spectral measurements in both steady and transient states,the phenomena of suppressed photolu-minescence(PL)emissions,shifted Raman signals and changed PL lifetimes provide strong evidences of efficient charge transfer at the 0D-2D interface.A series of spectral evolutions of heterostructures with various QDs overlapping concentrations at different laser powers are analyzed in details,which clarifies the dynamic competition between exciton and trion during an efficient doping of 3.9×10^(13)cm^(−2).The enhanced photoresponses(1.57×10^(4)A·W^(-1))and detectivities(2.86×10^(11)Jones)in 0D/2D phototransistors further demonstrate that the light-induced charge transfer is still a feasible way to optimize the performance of optoelectronic devices.These results are expected to inspire the basic understand-ing of interfacial physics at 0D/2D interfaces,and shed the light on promoting the development of mixed-dimensional op-toelectronic devices in the near future. | Ziwei Li Wen Yang Ming Huang Xin Yang Chenguang Zhu Chenglin He Lihui Li Yajuan Wang Yunfei Xie Zhuoran Luo Delang Liang Jianhua Huang Xiaoli Zhu Xiujuan Zhuang Dong Li Anlian Pan | 2021 | Opto-Electronic Advances2021，4，9： | 4 |
| 20 | Preparation and characterization of porous titanium using space-holder technique显示文摘基于钛的多孔的材料能在结构的应用被使用并且医药因为他们的优秀机械性质,在提高的温度,好腐蚀抵抗和奇妙的简历相容性植入。然而,大多数过去常生产多孔的金属罐头的方法仅仅给有限的孔和控制不了的毛孔形态学。在现在的学习,用空间持有者技术的粉末冶金学的一个最新发达的方法被用来与可控制的孔制作多孔的钛。词法特征和产品的机械性质充分被调查。结果证明孔在范围 55%75% ,并且与 ∼0.72 的平均球状,吝啬的毛孔尺寸是 600 μm。高原压力在 10 MPa 和 35 MPa 之间变化。是由 Gibson-Ashby 模型,预言了高原压力与增加减少孔。 | NIU Wenjuan BAI Chenguang QIU Guibao WANG Qiang WEN Liangying CHEN Dengfu DONG Lingyan | 2009 | Rare Metals2009，28，4： | 3 |
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