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| 1 | Factors predicting sensory and motor recovery after the repair of upper limb peripheral nerve injuries显示文摘OBJECTIVE: To investigate the factors associated with sensory and motor recovery after the repair of upper limb peripheral nerve injuries. DATA SOURCES: The online PubMed database was searched for English articles describing outcomes after the repair of median, ulnar, radial, and digital nerve injuries in humans with a publication date between 1 January 1990 and 16 February 2011. STUDY SELECTION: The following types of article were selected:(1) clinical trials describing the repair of median, ulnar, radial, and digital nerve injuries published in English; and(2) studies that reported sufficient patient information, including age, mechanism of injury, nerve injured, injury location, defect length, repair time, repair method, and repair materials. SPSS 13.0 software was used to perform univariate and multivariate logistic regression analyses and to investigate the patient and intervention factors associated with outcomes. MAIN OUTCOME MEASURES: Sensory function was assessed using the Mackinnon-Dellon scale and motor function was assessed using the manual muscle test. Satisfactory motor recovery was defined as grade M4 or M5, and satisfactory sensory recovery was defined as grade S3+ or S4.RESULTS: Seventy-one articles were included in this study. Univariate and multivariate logistic regression analyses showed that repair time, repair materials, and nerve injured were independent predictors of outcome after the repair of nerve injuries(P < 0.05), and that the nerve injured was the main factor affecting the rate of good to excellent recovery. CONCLUSION: Predictors of outcome after the repair of peripheral nerve injuries include age, gender, repair time, repair materials, nerve injured, defect length, and duration of follow-up. | Bo He Zhaowei Zhu Qingtang Zhu Xiang Zhou Canbin Zheng Pengliang Li Shuang Zhu Xiaolin Liu Jiakai Zhu | 2014 | Neural Regeneration Research2014，9，6： | 12 |
| 2 | Effectiveness of Catch-Up Vaccinations after COVID-19 Containment--China,2020显示文摘Introduction:In the early stages of the coronavirus disease 2019(COVID-19)epidemic in China,the highest level of public health emergency response(Level 1 Response)was launched in all province-level administrative divisions(PLADs)across the country.Provision of vaccination services was selectively suspended due to the physical distancing and gathering restrictions required of Level 1 Response.The purpose of this paper is to evaluate the impact of COVID-19 on vaccination services and the effectiveness of selective vaccination service suspension and catch-up vaccinations in China.Methods:Vaccine doses administered,routine vaccination coverage levels,catch-up vaccine doses administered,and coverage levels after the catch-up campaign were determined from individual vaccination records in sampled clinics,standard routine immunization administrative coverage reports,and catch-up vaccination activity reports submitted by PLADs between October 2019 and October 2020.Results:National Immunization Program(NIP)and non-NIP vaccine doses administered in sampled clinics decreased by 80% and 90%,respectively,compared with doses administered before the COVID-19 pandemic.Coverage with the birth dose of hepatitis B vaccine(HepB1)and the Bacillus Calmette-Guérin vaccine(BCG)—two vaccinations recommended to continue throughout the epidemic due to their timecritical nature—were maintained at over 85%,while coverage of other NIP vaccines decreased to below 60%by February 2020.Catch-up vaccination coverage of the 29 PLADs,excluding Xinjiang and Xizang(Tibet),began in April 2020 and exceeded 90%;Hubei catch-up coverage was 95% by October 2020.Conclusions and Implications for Public Health Practice:The COVID-19 pandemic had a great impact on China’s vaccination services.During the epidemic and time of local transmission of the coronavirus,HepB1,BCG,rabies vaccine for postexposure prophylaxis,and tetanus antitoxin(TAT)for wound prophylaxis were maintained at high levels.Of the 69 million vaccine doses postponed during the time of local transmission of the coronavirus,94% were administered in the catch-up campaign.China’s pandemic immunization practices may provide evidence for other countries’immunization programs. | Jing Wu Wenzhou Yu Lei Cao Lingsheng Cao Lance Rodewald Jiakai Ye Yifan Song Li Li Xiaoxue Liu Ning Wen Fuzhen Wang Lixin Hao Yixing Li Hui Zheng Keli Li Chao Ma Dan Wu Yanmin Liu Guomin Zhang Zhijie An Huaqing Wang Zundong Yin | 2020 | China CDC weekly2020，2，50： | 6 |
| 3 | Combination of Human Fas (CD95/Apo-1) Ligand with Adriamycin Significantly Enhances the Efficacy of Antitumor Response显示文摘hepatocellular 癌(HCC ) 的预后是差的,甚至与药品切除术和辅助 chemoradiotherapy 的联合治疗。解决这个问题,许多生物学的治疗被调查了。船边交货 ligand (FasL, CD95L ) 主要在激活的 T 淋巴细胞和生来的杀手(NK ) 房间被表示,并且在调停房间的免疫和有免疫力的 downregulation 起一个中央作用。几研究证明了 FasL 在 HCC 被表示。在现在的报告,我们准备了 recombinant 人 pET-22b (+)/FasL 蛋白质并且在一个鼠科的 HCC 肿瘤模型在 vitro 并且在肿瘤生长上在 HCC 房间上调查了 FasL 的效果。著名细胞毒素的化学疗法的试剂 adriamycin (ADM ) 用作控制。我们发现 FasL 有效地压制了 H22 肿瘤房间的生存能力并且显著地导致了 H22 房间的 apoptosis。与 FasL-ADM 对待的细胞的 apoptotic 层次比独自与 FasL 或 ADM 对待的那些显著地高,并且 FasL-ADM 联合导致了一非常在这个模型的肿瘤生长延期上的添加剂效果。结果建议 FasL 和另外的化学疗法的代理人的那个联合处理可以是一条新途径为 HCC 改进化疗的功效。 | Zhongchen Liu Ruizhen Liu Jinhua Qiu Ping Yin Fanghong Luo Jinhua Su Wenzhu Li Caixia Chen Xin Fan Jiakai Zhang Guohong Zhuang | 2009 | Cellular & Molecular Immunology2009，6，3： | 4 |
| 4 | Matrix metaHoproteinase-8 inhibitors mitigate sepsis-induced myocardial injury in rats显示文摘 | Zhou Xiaorui Lu Jiakai Chen Dong Wang Wei Cai Qing Li Tongxun Zhang Jinglan | 2014 | Chinese Medical Journal2014，，8： | 3 |
| 5 | Molecular cloning, characterization and expression analysis of a catalase gene in Paphia textile显示文摘Catalase is an important antioxidant protein that can protect organisms against various forms of oxidative damage by eliminating hydrogen peroxide. In this study, the catalase c DNA of Paphia textile(Pt CAT) was cloned using RTPCR and rapid amplification of c DNA ends(RACE). Pt CAT is 1 921 bp long and consists of a 5′-UTR of 50 bp, a 3′-UTR of 349 bp, and an ORF of 1 542 bp that encodes 513 amino acids with a molecular weight of 58.4 k D and an estimated isoelectric point of 8.2. Sequence alignment indicated that Pt CAT contained a highly conserved catalytic signature motif(^(61)FNRERIPERVVHAKGAG^(77)), a proximal heme-ligand signature sequence(^(352)RLFSYSDP^(359)), and three catalytic amino acid residues(H^(72), N^(145), and Y^(356)). Pt CAT also contains two putative N-glycosylation sites(^(34)NKT^(36) and ^(437)NFT^(439)) and a peroxisome-targeting signal(^(511)AQL^(513)). Furthermore, Pt CAT shares 53%–88% identity and 29%–89% similarity with other catalase amino acid sequences. Pt CAT m RNA was present in all tested organs, including the heart, digestive gland, adductor muscle, gonad, gill, and mantle, but its expression was highest in the digestive gland. High-temperature-induced stress produced two expression patterns of Pt CAT m RNA: first, an initial up-regulation followed by a down-regulation in the heart, digestive gland, and gonad and, second, consistent down-regulation in all other organs. These results demonstrate that Pt CAT is a typical member of the catalase family and might be involved in the responses to harmful environmental factors. | WU Xiangwei LI Jiakai TAN Jing LIU Xiande | 2016 | Acta Oceanologica Sinica2016，35，8： | 1 |
| 6 | RGD-FasL Induces Apoptosis in Hepatocellular Carcinoma显示文摘尽管有在动物模型获得的出色的结果,船边交货 ligand (FasL ) 的临床的使用被严重毒性作为 anticancer 药限制。死亡 ligands 的全身的毒性可以被使用编码膜界限死亡 ligands 的基因阻止,由指向的 transgene,通过也的表示指向了 transduction 或指向了抄写。肿瘤房间死亡的选择正式就职是有希望的 anticancer 策略。熔化蛋白质被熔化船边交货 ligand (FasL ) 的细胞外的领域到有选择地在肿瘤 endothelial 房间上指向 av3-integrins 的肽 arginine-glycine-aspartic 酸(RGD ) 创造。这研究的目的是在鼠科的 hepatocellular 癌(HCC ) 在肿瘤生长和幸存上评估 RGD-FasL 的效果肿瘤模型。有与 FasL 作为与那相比在 HCC 肿瘤模型上显示明显的镇压效果的 RGD-FasL 的处理(p < 0.05 ) 并且在这个模型在肿瘤生长延期上导致了更多的添加剂效果。RGD-FasL 处理显著地提高了老鼠幸存并且没引起有毒的效果,例如重量损失,机关失败,或另外的处理相关的毒性。Apoptosis 被流动 cytometric 分析和 TUNEL 试金检测;那些结果也证明 RGD-FasL 比 FasL 是为 H22 和 H9101 房间线的房间 apoptosis 的更多的有势力 inducer (p < 0.05 ) 。在结论, RGD-FasL 看起来是肿瘤房间死亡的低毒性的选择 inducer,它在现出症状之前的潜、临床的研究应得进一步的调查。而且,这条途径与治疗学的 recombinant 蛋白质为 complexing 目标 ligands 提供一种万用的技术。为了在 vivo,肿瘤和肝区分 FasL 的反肿瘤效果,纸巾被收获由染色的 Hematoxylin 和曙红(H&E ) 为坏死的房间,肿瘤房间,或 apoptotic 房间的证据检验。 | Zhongchen Liu Juan Wang Ping Yin Jinhua Qiu Ruizhen Liu Wenzhu Li Xin Fan Xiaofeng Cheng Caixia Chen Jiakai Zhang Guohong Zhuang | 2009 | Cellular & Molecular Immunology2009，6，4： | 1 |
| 7 | Coverage of 13-Valent Pneumococcal Conjugate Vaccine Among Children 0–15 Months of Age—9 Provinces,China,2019–2021显示文摘Summary What is already known on this topic?Limited data exist regarding the coverage of the 13-valent pneumococcal conjugate vaccine(PCV13)in China.A lack of official statistics,coupled with an insufficient body of published literature,hinders the accurate depiction of the current situation.What is added by this report?This study investigated the utilization of PCV13 and estimated its coverage in nine provinces across eastern,central,and western China between 2019 and 2021.Despite an annual increase in PCV13 usage during this period,the overall coverage remained suboptimal. | Lijun Liu Zhaonan Zhang Xixi Zhang Changsha Xu Yifan Song Li Li Jiakai Ye Zhiguo Wang Hui Liang Weiyan Zhang Ling Lin Ning Li Shujun Zhang Qianli Ma Wen Du Yongzhuo Jiao Lingsheng Cao Qi Qi Lei Cao Wenzhou Yu | 2023 | China CDC weekly2023，5，17： | 1 |
| 8 | Vaccination Guidelines During and After the COVID-19 Epidemic in China显示文摘In late December 2019,clinicians in Hubei Province noticed and reported to health authorities a cluster of cases of pneumonia of unknown etiology(PUE)that turned out to be the start of the coronavirus disease 2019(COVID-19)pandemic(1).By January 29,2020,all provincial-level administrative divisions(PLADs)across the country had launched their highest public health emergency responses(Level 1 responses)(2-3). | Wenzhou Yu Yuanqiu Li Jing Wu Fuzhen Wang Ning Wen Lance Rodewald Lixin Hao Yixing Li Hui Zheng Keli Li Chao Ma Dan Wu Lei Cao Lingsheng Cao Jiakai Ye Yanmin Liu Guomin Zhang Wen Du Zhijie An Huaqing Wang Zundong Yin | 2020 | China CDC weekly2020，2，34： | 1 |
| 9 | AI-WSN:Adaptive and Intelligent Wireless Sensor Network显示文摘 | Gursel Serpen Jiakai Li | 2013 | Procedia Computer Science2013，，20： | 1 |
| 10 | CT-Guided percutaneous chemical ablation of adrenal neoplasms 显示文摘 | Yueyong Xiao Jinlin Tian Jiakai Li | 2008 | A JR2008，190，： | 1 |
| 11 | Band-structure-engineered high-gain LWIR photodetector based on a type-Ⅱ superlattice显示文摘The LWIR and longer wavelength regions are of particular interest for new developments and new approaches to realizing long-wavelength infrared(LWIR)photodetectors with high detectivity and high responsivity.These photodetectors are highly desirable for applications such as infrared earth science and astronomy,remote sensing,optical communication,and thermal and medical imaging.Here,we report the design,growth,and characterization of a high-gain band-structure-engineered LWIR heterojunction phototransistor based on type-Ⅱ superlattices.The 1/e cut-off wavelength of the device is 8.0 pm.At 77 K,unity optical gain occurs at a 90 mV applied bias with a dark current density of 3.2×10^(-7)A/cm^(2).The optical gain of the device at 77 K saturates at a value of 276 at an applied bias of 220 mV.This saturation corresponds to a responsivity of 1284 A/W and a specific detectivity of 2.34×10^(13)cm Hz^(1/2)/W at a peak detection wavelength of~6.8 pm.The type-Ⅱ superlattice-based high-gain LWIR device shows the possibility of designing the high-performance gain-based LWIR photodetectors by implementing the band structure engineering approach. | Arash Dehzangi Jiakai Li Manijeh Razeghi | 2021 | Light(Science & Applications)2021，10，2： | 1 |
| 12 | TOSSIM simulation of wireless sensor net- work serving as hardware platform for Hopfield neural net con- figured for max independent set 显示文摘 | Li Jiakai Gursel S | 2011 | Procedia Computer Sci- ence2011，，6： | 1 |
| 13 | Policy Orientation of China Consumption Tax Reform in Ecological Civilization显示文摘The consumption tax reform is not only an important point of the construction of ecological civilization,but also a livelihood project related to the vital interests of consumers in China,which has aroused a heated discussion.Current popular ideas and plans of the consumption tax reform are directly moved by the developed countries.Therefore,it is bound to lack the support of the people.It is not adverse to the construction of ecological civilization and not conductive to the great rejuvenation of the Chinese dream.In the era of ecological civilization,the reform of the consumption tax needs to adopt the system thinking,taking into account multiple aspects of China’s tax system construction,tax fairness and environmental protection.Only by adjusting the taxation scope,refining the rate and perfecting tax link,etc.from overall thinking can the reform be successful. | Li Jiakai | 2015 | 学术界2015，，9： | 0 |
| 14 | Penile erectile dysfunction after brachial plexus root avulsion injury in rats显示文摘Our previous studies have demonstrated that some male patients suffering from brachial plexus injury,particularly brachial plexus root avulsion,show erectile dysfunction to varying degrees.However,the underlying mechanism remains poorly understood.In this study,we evaluated the erectile function after establishing brachial plexus root avulsion models with or without spinal cord injury in rats.After these models were established,we administered apomorphine(via a subcutaneous injection in the neck) to observe changes in erectile function.Rats subjected to simple brachial plexus root avulsion or those subjected to brachial plexus root avulsion combined with spinal cord injury had significantly fewer erections than those subjected to the sham operation.Expression of neuronal nitric oxide synthase did not change in brachial plexus root avulsion rats.However,neuronal nitric oxide synthase expression was significantly decreased in brachial plexus root avulsion + spinal cord injury rats.These findings suggest that a decrease in neuronal nitric oxide synthase expression in the penis may play a role in erectile dysfunction caused by the combination of brachial plexus root avulsion and spinal cord injury. | Guo Fu Bengang Qin Li Jiang Xijun Huang Qinsen Lu Dechun Zhang Xiaolin Liu Jiakai Zhu Jianwen Zheng Xuejia Li Liqiang Gu | 2014 | Neural Regeneration Research2014，9，20： | 0 |
| 15 | Vaccination Vehicles for COVID-19 Immunization—China,2021显示文摘Background:Recently,developed vaccination vehicles were repurposed and deployed for coronavirus disease 2019(COVID-19)vaccination in China.We described the vehicles and reported an evaluation of vaccination throughput of these vehicles for COVID-19 vaccination in China.Methods:We obtained daily reports of COVID-19 vaccine doses administered in vehicles in Hubei Province between March 16 and 29 of 2021.We determined the rate of COVID-19 vaccines given and evaluated the applicability of vaccination vehicles for COVID-19 vaccination.Results:Vehicles with 2 vaccination stations are suitable for several real-world scenarios.Vehicles administered an average of 72 COVID-19 vaccine doses per hour,with an upper limit of 145 doses per hour.Conclusion:Vaccination vehicles can save human and financial resources and provide high quality,effective,convenient,and rapid on-site vaccination services;they can increase the pace of COVID-19 vaccination. | Hong Lei Lingsheng Cao Yi Gong Wenzhou Yu Lei Cao Jiakai Ye Yifan Song Li Li | 2021 | China CDC weekly2021，3，34： | 0 |
| 16 | Relating the composition of continental margin surface sediments from the Ross Sea to the Amundsen Sea,West Antarctica,to modern environmental conditions显示文摘Investigating the multiple proxies involving productivity,organic geochemistry,and trace element(TE)enrichment in surface sediments could be used as paleoenvironment archives to gain insights into past and future environmental conditions changes.We present redox-sensitive TEs(Mn,Ni,Cu,U,P,Mo,Co,V,Zn,and Cd),productivity-related proxies(total organic carbon and opal),and total nitrogen and CaCO_(3) contents of bulk surface sediments of this area.The productivity proxies from the shelf and coastal regions of the Ross and the Amundsen seas showed that higher productivity was affiliated with an area of nutrient-rich deep water upwelling.The upwelling of weakly corrosive deep water may be beneficial for preserving CaCO_(3),while highly corrosive dense water,if it forms on the shelf near the coastal region(coastal polynya),could limit the preservation of CaCO_(3) in modern conditions.There were no oxic or anoxic conditions in the study area,as indicated by the enrichment factors of redox-sensitive TEs(Mn,Co,and U).The enrichment factor of Cd,which is redox-sensitive,indicated suboxic redox conditions in sediment environments because of high primary productivity and organic matter preservation/decomposition.The enrichment factors of other redox-sensitive TEs(P,Ni,Cu,V,and Zn)and the correlations between the element/Ti ratio with productivity and nutrient proxies indicated that the organic matter decomposed,and there was massive burial of phytoplankton biomass.There was variation in the enrichment,such that sediments were enriched in P,Mo,and Zn,but depleted in Ni,Cu,and V. | WANG Jiakai LI Tiegang TANG Zheng XIONG Zhifang LIU Yanguang CHEN Zhihua CHANG Fengming | 2022 | Advances in Polar Science2022，33，1： | 0 |
| 17 | Combining ability for main quality traits in peanut(Arachis hypogaea L.)显示文摘High-oleic peanuts has been recognized by processing sectors,seed sellers and consumers for their longer shelf life,longer seed life and mutiple healthe benefits.High oleate is becoming a requisite for varietal releases in many peanut breeding programs at present.To select desirable parents for high-oleic peanut breeding,the study was conducted to evaluate the combining ability of 5 high-oleic donors from our research team,based on quality of individual single seeds.General combining ability was significant for oleic,linoleic,stearic and palmitic acid,oil and protein,while specific combining ability was significant for the traits except oil.Among them,oil content was found to be conditioned solely by additive gene actions,and for other quality traits,additive gene effects were more important than non-additive gene effects.High-oleic CTW and normal-oleic Xiaojingsheng were selected as the best general combiners for peanut oleic acid improvement.Narrow-sense heritability was high for quality traits other than protein,suggesting that there was high potential for genetic improvement in these traits. | Chuantang Wang Zhiwei Wang Hongwei Han Jiakai Li Hongjv Li Xiushan Sun Guosheng Song | 2021 | Oil Crop Science2021，6，4： | 0 |
| 18 | In-Orbit Calibration Uncertainty of the Microwave Radiation Imager on board Fengyun-3C显示文摘This study evaluates the in-orbit calibration uncertainty(CU)for the microwave radiation imager(MWRI)on board the Chinese polar-orbiting meteorological satellite Fengyun-3 C(FY-3 C).Uncertainty analysis of the MWRI provides a direct link to the calibration system of the sensor and quantifies the calibration confidence based on the prelaunch and postlaunch measurements.The unique design of the sensor makes the uncertainty in the calibration of the sensor highly correlate to the uncertainty in the brightness temperature(TB)measured at the hot view,while the cold view has negligible impacts on the calibration confidence.Lack of knowledge on the emission of the hot-load reflector hampers the MWRI calibration accuracy significantly in the descending passes of the orbits when the hotload reflector is heated nonuniformly by the solar illumination.Radiance contamination originating from the satellite and in-orbit environments could enter the primary reflector via the hot view and further impinge on the CU,especially at the 10.65-GHz channels where the main-beam width is much broader than that of higher-frequency channels.The monthly-mean CU is lower than 2 K at all channels,depending on the observed earth scenes and in-orbit environments,and the month-to-month variation of CU is also noticed for all channels.Due to the uncertainty in the emissive hot-load reflector,CU in the descending passes is generally larger than that in the ascending orbits.Moreover,up to 1-K CU difference between the ocean and land scenes is found for the 10.65-GHz channels,while this difference is less than 0.1 K at the 89-GHz channels. | Xinxin XIE Wanting MENG Jiakai HE Weimin YU Xue LI | 2021 | Journal of Meteorological Research2021，35，6： | 0 |
| 19 | Transcutaneous auricular vagus nerve stimulation would be an alternative to implantable cervical vagus nerve stimulation in some situation显示文摘Implantable cervical vagus nerve stimulation(i VNS) is a representative and promising neuromodulation.However,the invasive nature restricts its application.Traditional auricular acupuncture treatment has a long history.The auricular branch of the vagus nerve(ABVN) is a branch on the surface of the ear.Some studies demonstrates that transcutaneous auricular vagus nerve stimulation(ta VNS) would achieve similar effects as i VNS.Ta VNS and i VNS share a common anatomical basis and acting mechanism.In this article,we made a comparison between i VNS and ta VNS in indications and efficacy.The recent studies have revealed similar clinical efficacy of ta VNS,ta VNS would expand the indication of i VNS.Highquality clinical evidences are needed before ta VNS become be an alternative of i VNS. | HE Jiakai ZHANG Jinling WANG Yu LI Shaoyuan FANG Jiliang ZHANG Shuai ZHAO Yanan ZHAI Weihang GAO Deqiang LI Ran JIANG Yuhang CHEN Zehao JIA Baohui RONG Peijing | 2023 | Journal of Traditional Chinese Medicine2023，43，3： | 0 |
| 20 | Modified Coffin-Manson equation to predict the fatigue life of structural materials subjected to mechanical-thermal coupling non-coaxial loading显示文摘With regard to the structures subjected to severe mechanical-thermal coupling fatigue conditions,the consistency between service conditions and loading conditions was the prerequisite for the fatigue prop-erties test and fatigue life prediction.A miniature piezoelectric-driven instrument integrating with a tripodal piezoelectric actuator and envelope-type heating function was developed to investigate the mechanical-thermal coupling fatigue properties and obtain the fatigue life of materials under approximate service conditions.A physical model was described to quantitatively calculate the alternating deformation under the mechanical-thermal coupling tensile-bending combined condition.Accordingly,a fatigue life prediction method based on the Coffin-Manson equation under tensile-bending combined loading was proposed to estimate the mechanical-thermal coupling fatigue life in terms of the total coupling defor-mation and plastic strain amplitude.The feasibility of the proposed instrument was verified through the analysis of displacement responses of high entropy alloy specimens under the thermal-mechanical cou-pling tensile-bending combined condition at temperatures ranging from RT to 600°C.The comparison between fatigue lives directly measured through thermal-mechanical coupling experiments and theoreti-cally predicted fatigue lives indicated the availability of the modified Coffin-Manson equation. | Zhichao Ma Chaofan Li Wei Zhang Shenghui Wang Jiakai Li Hongwei Zhao Luquan Ren | 2023 | Journal of Materials Science & Technology2023，，29： | 0 |
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