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| 1 | Efficacy and Safety of Yanggan Jian in Hepatitis B Virusrelated Decompensated Cirrhosis:A Randomized,Doubleblind,Controlled Trial显示文摘Background and Aims:The aim was to evaluate the efficacy and safety of Yanggan Jian(YGJ)in HBV-infected patients with decompensated cirrhosis.Methods:This randomized,double-blind controlled trial enrolled 160 patients with HBV-related decompensated cirrhosis who were already receiving or about to start antiviral therapy.Patients were randomly assigned to receive YGJ or placebo for 24 weeks,and were followed-up to 36 weeks.The primary outcome was the proportion of patients with a≥2 point reduction in Child-Turcotte-Pugh(CTP)score from baseline at week 24.Secondary outcomes were CTP class and score,serum liver function indices,mortality,incidence of hepatocellular carcinoma and variceal bleeding.Results:The proportion of patients with a CTP score reduction≥2 was significantly greater in the YGJ than in the placebo group(p=0.009);the percentage of patients with CTP class C was significantly less than that in the placebo group(p<0.05),and the YGJ group had a significantly greater mean change from baseline in CTP score at week 24(p=0.034).The improvement in measured values and change from baseline of prothrombin time,serum albumin,platelets,cholinesterase,international normalized ratio,and activated partial thromboplastin time were significantly better with YGJ than with placebo.Between-group differences in cumulative rates of variceal bleeding,hepatocellular carcinoma,death,or the frequency of any adverse event(AE),AEs related to treatment,or discontinuation because of AEs were not significant.Conclusions:YGJ significantly improved CTP scores and hepatic synthetic and reserve function in patients with HBV-related decompensated cirrhosis,and was safe and well tolerated. | Long Chen Chaoqun Zhao Weili Yao Wei Liu Hua Zhang Yongping Mu Hong Cai Dongying Xue Chengbao Wang Wan’e Wang Yuehong Lin Jiamei Chen Ping Liu | 2023 | Journal of Clinical and Translational Hepatology2023,11,1: | 3 |
| 2 | Versatile metal graphitic nanocapsules for SERS bioanalysis显示文摘The novel graphitic nanomaterial of metal graphitic nanocapsules(MGNs) with superior stability, unique optical properties and biocompatibility possess great potential in biomedical and bioanalytical applications. The graphitic shell can quench the background fluorescence interference from external environments via a fluorescence resonance energy transfer(FRET) process and even avoid unnecessary reactions catalyzed by inner metal core. The graphitic shell with several characteristic Raman bands itself can act as Raman signal probe or internal standard(IS), especially the 2D-band within the cellular Raman-silent region helps to reduce the interference signals from external conditions. The present context attempts to give a comprehensive overview about the preparation and unique properties of MGNs as well as their applications in SERS biodetection and bioimaging. | Shengkai Li Jiamei Xu Shen Wang Xin Xia Long Chen Zhuo Chen | 2019 | Chinese Chemical Letters2019,30,9: | 2 |
| 3 | Performance and Mechanism of Standard Nano-TiO2 (P-25) in PhotocatalyticDisinfection of Foodbome Microorganisms-Salmonella typhimurium and Listeria monocytogenes显示文摘 | Long Men Wang Jiamei Zhuang Hong | 2013 | Food Control2013,39,1: | 1 |
| 4 | Comparison of transcatheter arterial chemoembolization and microsphere embolization for treatment of unresectable hepatocellular carcinoma: a meta-analysis显示文摘 | Feng Xie Jiajie Zang Xiaojing Guo Feng Xu Rongxi Shen Long Yan Jiamei Yang Jia He | 2012 | Journal of Cancer Research and Clinical Oncology2012,,: | 1 |
| 5 | Clinical Effects of the COVID-19 Pandemic Among the Uninfected Pregnant Women—6 PLADs,China,2019−2020显示文摘Summary What is already known about this topic?The coronavirus disease 2019(COVID-19)pandemic potentially affected prenatal care quality and maternal and fetal outcomes globally.What is added by this report?During COVID-19 pandemic period,the rates of caesarean sections(CS)and preterm birth for uninfected pregnant women increased slightly in areas that were relatively severely impacted by the pandemic in China. | Bin Wang Hang An Huanqing Hu Wei Zhao Bahabaike Jiangtulu Shuo Wang Jiamei Wang Junxi Chen Manman Long Zewu Li Yu Jin Yuhuan Li Huiting Chen Tao Xue Xiqing Li Kexin Li Wei Du Suhong Gao Jiangli Di Xiaohong Liu Rongwei Ye Zhiwen Li | 2021 | China CDC weekly2021,3,10: | 0 |
| 6 | Mean square stability of discrete-time linear systems with random impulsive disturbances显示文摘Dear editor,In the real world,many dynamic processes may experience abrupt state [1] or parameter changes. Mathematically,these abrupt changes of state can be modeled as ideal impulsive effects. And also,the moments at which impulses occur might be uncertain because they are triggered by unpredictable factors. | Jiamei LONG Yuqian GUO Weihua GUI | 2023 | Science China(Information Sciences)2023,66,6: | 0 |