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| 1 | Influence of different mining layouts on the mechanical properties of coal显示文摘Non-pillar mining,top-coal caving and protected coal seam mining are the most popular mining methods in coal exploitation,and the different mining layouts will change the stress state and failure mechanism of coal in front of the working face.In this paper,mining-induced mechanical behaviors under three mining layouts have been simulated in the laboratory to investigate the effects of mining layouts on the deformation and strength of coal.Furthermore,the coal failure mechanism under different mining layouts is analyzed microscopically.The experimental results indicate that the stage characteristics of the coal deformation are obvious.Under the serial action of non-pillar mining,top-coal caving and protected coal seam mining layouts,the values of radial deformation,volume strain and Poisson's ratio increase,while the peak strength and deformation modulus decrease at the same buried depth,and the peak strength under non-pillar mining,top-coal caving and protected coal seam mining is about 3.0,2.5 and 2.0 times of the initial confining pressure,respectively.The results also indicate that the trend of the coal deformation decreases with the increase of the buried depth under the same mining layout,while the strength and deformation modulus increase,and the failure mechanism under three mining layouts is dominated with shear/tensile failure. | Xie Heping Zhao Xiaoping Liu Jianfeng Zhang Ru Xue Dongjie | 2012 | International Journal of Mining Science and Technology2012，22，6： | 14 |
| 2 | EFFECTS OF POLISHING PARAMETERS ON MATERIAL REMOVAL FOR CURVED OPTICAL GLASSES IN BONNET POLISHING显示文摘The paper firstly analyzes the influence factor on material removal rate of curved optical work-pieces in the bonnet polishing.Then the experiments are conducted to reveal the effects of several polishing parameters on the material removal rate when the spherical optical glasses are polished with different curvature radius,such as the decrement of the bonnet,the rotational speed of the bonnet and the curvature radius of the work-piece's surface using a bonnet trial-manufacturing machine developed by our assignment groups.In the end,the curvilinear relationships between these parameters and the material removal rate are acquired and the laws of the effects on material removal rate in bonnet polishing by several parameters are given.When the spherical-pieces are polished with smaller curvature radius,it is not proportional to either bonnet decrement or bonnet rotational speed as described by the Preston equation although the removal rate increases as the relative velocity or the applied pressure increases.Therefore,for the purpose of calculating more accurately the material removal of the spherical work-pieces,the Preston equation should be modified and studied further. | SONG Jianfeng YAO Yingxue XIE Dagang GAO Bo YUAN Zhejun | 2008 | Chinese Journal of Mechanical Engineering2008，21，5： | 10 |
| 3 | Epidemiological and etiological investigation of dengue fever in the Fujian province of China during 2004–2014显示文摘Dengue fever(DF) is a vector-borne disease and a tremendous socioeconomic burden on tropical and subtropical countries worldwide. To explore the characteristics of DF epidemic in the Fujian province, information of DF cases in Fujian during 2004–2014 was collected and analyzed. The complete E genes of 48 viral isolates were amplified and sequenced for phylogenetic analysis. A total of 733 cases was reported, of which 612(83.5%) occurred during the peak period from August to October. Additionally, 76%(190/250) of imported cases originated from Southeast Asia countries, by the epidemiological investigation. Phylogenetic analysis of the 48 viral isolates revealed that three genotypes(I, IV, V) of DENV1, and one genotype each of DENV2(cosmopolitan) and DENV3(I) circulated in Fujian during 2004–2014. Similar to the results of the epidemiological investigations, the source of most of the viral isolates, including imported and indigenous cases, may be Southeast Asia countries; however, importation from adjacent provinces was also observed in recent years. Overall, DF is considered an imported epidemic disease in Fujian. Increasing diversity of the viral source and geographic expansion of the area affected by DF in recent years highlights the necessity for strengthening surveillance of the DF epidemic and developing strategies for DF prevention and control in Fujian. | Jinzhang Wang Hongbing Chen Meng Huang Yongjun Zhang Jianfeng Xie Yansheng Yan Kuicheng Zheng Yuwei Weng | 2017 | Science China(Life Sciences)2017，60，1： | 9 |
| 4 | Zea mays(L.) P1 locus for cob glume color identified as a post-domestication selection target with an effect on temperate maize genomes显示文摘Artificial selection during domestication and post-domestication improvement results in loss of genetic diversity near target loci. However, the genetic locus associated with cob glume color and the nature of the genomic pattern surrounding it was elusive and the selection effect in that region was not clear. An association mapping panel consisting of 283 diverse modern temperate maize elite lines was genotyped by a chip containing over 55,000 evenly distributed SNPs. Ten-fold resequencing at the target region on 40 of the panel lines and 47 tropical lines was also undertaken. A genome-wide association study(GWAS) for cob glume color confirmed the P1 locus, which is located on the short arm of chromosome 1, with a-log10 P value for surrounding SNPs higher than the Bonferroni threshold(α/n, α < 0.001) when a mixed linear model(MLM) was implemented. A total of 26 markers were identified in a 0.78 Mb region surrounding the P1 locus, including 0.73 Mb and 0.05 Mb upstream and downstream of the P1 gene, respectively. A clear linkage disequilibrium(LD) block was found and LD decayed very rapidly with increasing physical distance surrounding the P1 locus. The estimates of π and Tajima's D were significantly(P < 0.001) lower at both ends compared to the locus. Upon comparison of temperate and tropical lines at much finer resolution by resequencing(180-fold finer than chip SNPs), a more structured LD block pattern was found among the 40 resequenced temperate lines. All evidence indicates that the P1 locus in temperate maize has not undergone neutral evolution but has been subjected to artificial selection during post-domestication selection or improvement. The information and analytical results generated in this study provide insights as to how breeding efforts have affected genome evolution in crop plants. | Chuanxiao Xie Jianfeng Weng Wenguo Liu Cheng Zou Zhuanfang Hao Wenxue Li Minshun Li Xiaosen Guo Gengyun Zhang Yunbi Xu Xinhai Li Shihuang Zhang | 2013 | The Crop Journal2013，1，1： | 6 |
| 5 | Creation of targeted inversion mutations in plants using an RNA-guided endonuclease显示文摘Inversions are DNA rearrangements that are essential for plant gene evolution and adaptation to environmental changes. We demonstrate the creation of targeted inversions and previously reported targeted deletion mutations via delivery of a pair of RNA-guided endonucleases(RGENs) of CRISPR/Cas9. The efficiencies of the targeted inversions were2.6% and 2.2% in the Arabidopsis FLOWERING TIME(At FT) and TERMINAL FLOWER 1(At TFL1)loci, respectively. Thus, we successfully established an approach that can potentially be used to introduce targeted DNA inversions of interest for functional studies and crop improvement. | Congsheng Zhang Changlin Liu Jianfeng Weng Beijiu Cheng Fang Liu Xinhai Li Chuanxiao Xie | 2017 | The Crop Journal2017，5，1： | 6 |
| 6 | 溃疡性结肠炎内镜下严重度指数(UCEIS评分)与Mayo内镜评分(MES)用于预测急性重症结肠炎患者行肠切除术的比较研究显示文摘背景溃疡性结肠炎内镜下严重度指数(UCEIS)和Mayo内镜评分(MES)都是溃疡性结肠炎(UC)内镜下严重程度的客观评估方法,然而,对于这两种评分方法能否用于筛选出需要行结肠切除术的急性重症结肠炎患者,目前仍不明了。方法:对2012年1月至2016年5月间连续收治的ASC患者进行回顾性分析。提取并分析入组患者的人口统计资料、既往治疗史、疾病特征资料、实验室指标、药物治疗及内镜评估等资料。主要结局指标是住院和随访期间需行结肠切除术的患者比例。结果:92例患者纳入研究,其中37例(40.2%)需行结肠切除术。多因素分析显示,UCEIS评分是需行结肠切除术的独立预测因素(OR=3.25,95%CI:1.77~5.97;P<0.001)。UCEIS评分的ROC曲线下面积为0.85;以7分作为最佳阈值,其预测需行结肠切除术的敏感度为60.3%,特异度为85.5%。UCEIS评分对于需要行结肠切除术的预测价值优于MES评分,后者曲线下面积仅为0.65。当UCEIS评分≥7分时,有80%的ASC患者最终需行结肠切除术。结论:预测ASC患者的肠切除风险,UCEIS评分优于MES评分。对于USEIS≥7分的患者,由于其药物治疗失败风险较高,因此,可考虑早期行结肠切除术。 | Tingbin Xie Tenghui Zhang Chao Ding Xujie Dai Yi Li Zhen Guo Yao Wei Jianfeng Gong Weiming Zhu Jieshou Li | 2018 | Gastroenterology Report2018，6，1： | 6 |
| 7 | Effects of high-frequency oscillatory ventilation and conventional mechanical ventilation on oxygen metabolism and tissue perfusion in sheep models of acute respiratory distress syndrome显示文摘 | Liu Songqiao Huang Yingzi Wang Maohua Chen Qiuhua Liu Ling Xie Jianfeng Tan Li Guo Fengmei Yang Congshan Pan Chun Yang Yi Qiu Haibo | 2014 | Chinese Medical Journal2014，，18： | 6 |
| 8 | Enabling Technologies in the Problem Solving Environment HEDP显示文摘Enabling technologies are those technologies preparing input data,analyzing output data and facilitating the whole processes for numerical simulations.This paper outlines current enabling technologies for large-scale multidisciplinary simulations used in the High End Digital Prototyping(HEDP)system,a problem solving environment equipped with capability of mesh generation and large-scale visualization.A problem solving environment is a computer system that provides all the computational facilities necessary to solve a target class of problems.Mesh generation continues to be the pacing technology for a practical numerical analysis,which is essential to yielding an accurate and efficient solution.Large-scale visualization maps the massive data to some kinds of scenes interactively,which can be realized through a tiled display wall system with distributed visualization capability.HEDP is designed for large-scale andmultidisciplinary simulations,and there are four categories of modules involved,namely pre-processing module,computing module,post-processing module,and platform control module.All these modules are coupled through a software bus,which makes the modules integrated seamlessly.Detailed design principles and applications of the HEDP environment are addressed in this paper. | Lijun Xie Yao Zheng Jianjun Chen Jianfeng Zou | 2008 | Communications in Computational Physics2008，4，10： | 6 |
| 9 | Dark matter direct search sensitivity of the PandaX-4T experiment显示文摘The Panda X-4T experiment, a 4-ton scale dark matter direct detection experiment, is being planned at the China Jinping Underground Laboratory. In this paper we present a simulation study of the expected background in this experiment. In a 2.8-ton fiducial mass and the signal region between 1-10 keV electron equivalent energy, the total electron recoil background is found to be 4.9 × 10^(-5) kg^(-1) d^(-1) keV^(-1). The nuclear recoil background in the same region is 2.8 × 10^(-7) kg^(-1) d^(-1) keV^(-1). With an exposure of 5.6 ton-years, the sensitivity of Panda X-4 T could reach a minimum spin-independent dark matter-nucleon cross section of 6 × 10^(-48) cm^2 at a dark matter mass of 40 Ge V/c^2. | HongGuang Zhang Abdusalam Abdukerim Wei Chen Xun Chen YunHua Chen XiangYi Cui BinBin Dong DeQing Fang ChangBo Fu Karl Giboni Franco Giuliani LinHui Gu XuYuan Guo ZhiFan Guo Ke Han ChangDa He ShengMing He Di Huang XingTao Huang Zhou Huang Peng Ji XiangDong Ji YongLin Ju ShaoLi Li Yao Li Heng Lin HuaXuan Liu JiangLai Liu YuGang Ma YaJun Mao KaiXiang Ni JinHua Ning XiangXiang Ren Fang Shi AnDi Tan AnQing Wang Cheng Wang HongWei Wang Meng Wang QiuHong Wang SiGuang Wang XiuLi Wang XuMing Wang Zhou Wang MengMeng Wu ShiYong Wu JingKai Xia MengJiao Xiao PengWei Xie BinBin Yan JiJun Yang Yong Yang ChunXu Yu JuMin Yuan JianFeng Yue Dan Zhang Tao Zhang Li Zhao QiBin Zheng JiFang Zhou Ning Zhou XiaoPeng Zhou | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，3： | 6 |
| 10 | Identification of Functional Genetic Variations Underlying Drought Tolerance in Maize Using SNP Markers显示文摘Single nucleotide polymorphism (SNP) is a common form of genetic variation and popularly exists in maize genome. An Illumina GoldenGate assay with 1 536 SNP markers was used to genotype maize inbred lines and identified the functional genetic variations underlying drought tolerance by association analysis. Across 80 lines, 1 006 polymorphic SNPs (65.5% of the total) in the assay with good call quality were used to estimate the pattern of genetic diversity, population structure, and familial relatedness. The analysis showed the best number of fixed subgroups was six, which was consistent with their original sources and results using only simple sequence repeat markers. Pairwise linkage disequilibrium (LD) and association mapping with phenotypic traits investigated under water-stressed and well-watered regimes showed rapid LD decline within 100-500 kb along the physical distance of each chromosome, and that 29 SNPs were associated with at least two phenotypic traits in one or more environments, which were related to drought-tolerant or drought-responsive genes. These drought-tolerant SNPs could be converted into functional markers and then used for maize improvement by marker-assisted selection. | Zhuanfang Hao Xinhai Li Chuanxiao Xie Jianfeng Weng Mingshun Li Degui Zhang Xiaoling Liang Lingling Liu Sisi Liu Shihuang Zhang | 2011 | Journal of Integrative Plant Biology2011，53，8： | 5 |
| 11 | Synthesis and characterization of amphiphilic graphene显示文摘A simple and effective method for the preparation of amphiphilic graphene(AG)is presented under an organic solvent-free synthetic condition.The synthetic route first involves a cyclization reaction between carboxylic groups on graphene oxide and the amino groups on 5,6-diaminopyrazine-2,3-dicarbonitrile,and subsequent reduction by hydrazine.Results of UV-vis spectroscopy,Fourier transformed infrared spectroscopy(FT-IR),X-ray photoelectron spectroscopy(XPS),thermogravimetric analysis(TGA)and Raman spectroscopy have confirmed that the covalent functionalization of graphene can be achieved through the formation of imidazo[4,5-b]pyrazine on the graphene sheets.As a result,AG can be successfully dispersed in water and common organic solvents.This work successfully provides a facile and efficient way to fabricate AG and may extend the potential applications of graphene-based materials in nanoelectronic devices,polymer fillers and biological field. | DU ZhuZhu AI Wei ZHAO JianFeng XIE LingHai HUANG Wei | 2014 | Science China(Technological Sciences)2014，57，2： | 5 |
| 12 | Research on the Programming Language for Symmetric Cryptographic Algorithms显示文摘 | LI Fenghua YAN Junzhi XIE Rongna MA Jianfeng | 2010 | Chinese Journal of Electronics2010，19，2： | 4 |
| 13 | ZnO-based micromotors fueled by CO_(2):the first example of self-reorientation-induced biomimetic chemotaxis显示文摘Synthetic chemotactic micro/nanomotors are envisioned to actively‘seek out’targets by following specific chemicals,but they are mainly powered by bioincompatible fuels and only show pseudochemotaxis(or advanced chemokinesis)due to their weak self-reorientation capabilities.Here we demonstrate that synthetic ZnO-based Janus micromotors can be powered by the alternative biocompatible fuel of C0_(2);and further provide the first example of self-reorientation-induced biomimetic chemotaxis using them.The ZnO-based micromotors are highly sensitive to dissolved C0_(2) in water,which enables the corrosion of ZnO to continuously occur by providing H+through hydration.Thus,they can autonomously move even in water exposed to air based on self-diffusiophoresis.Furthermore,they can sense the local C0_(2) gradient and perform positive chemotaxis by self-reorientations under the phoretic torque.Our discovery opens a gate to developing intelligent micro/nanomotors powered by,and sensitive to,biocompatible atmospheric or endogenous gaseous chemicals for biomedical and environmental applications. | Fangzhi Mou Qi Xie Jianfeng Liu Shengping Che Lamya Bahmane Ming You Jianguo Guan | 2021 | National Science Review2021，8，11： | 3 |
| 14 | Single-cell transcriptomes of peripheral blood cells indicate and elucidate severity of COVID-19显示文摘The blood and immune system of coronavirus disease 2019(COVID-19)infected patients are dysfunctional,and numerous studies have been conducted to resolve their characteristics and pathogenic mechanisms.Nevertheless,the variations of immune responses along with disease severity have not been comprehensively documented.Here,we profiled the single-cell transcriptomes of 96,313 peripheral blood mononuclear cells(PBMCs)derived from 12 COVID-19 patients(including four moderate,four severe and four critical cases)and three healthy donors.We showed that proliferative CD8 effector T cells with declined immune functions and cytotoxicity accumulated in the critical stage.By contrast,the quantity of natural killer(NK)cells was significantly reduced,while they exhibited enhanced immune activities.Notably,a gradually attenuated responseto COVID-19 along with disease severity was observed in monocytes,in terms of cellular composition,transcriptional discrepancy and transcription factor regulatory network.Furthermore,we identified immune cell-type dependent cytokine signatures distinguishing the severity of COVID-19 patients.In addition,cell interactions between CD8 effector T/NK cells and monocytes mediated by inflammatory cytokines were enhanced in moderate and severe stages,but weakened in critical cases.Collectively,our work uncovers the cellular and molecular players underlying the disordered and heterogeneous immune responses associated with COVID-19 severity,which could provide valuable insights for the treatment of critical COVID-19 patients. | Xiaowei Xie Xuelian Cheng Gaoxiang Wang Biao Zhang Mengyao Liu Liting Chen Hui Cheng Sha Hao Jianfeng Zhou Ping Zhu Tao Cheng | 2021 | Science China(Life Sciences)2021，64，10： | 3 |
| 15 | The Progress of CDIO Engineering Education Reform in Several China Universities: A Review显示文摘 | Bai Jianfeng Lei Hu Yanfen Li Zhen Tian Lili Xie Lijun Wang Mingyuan Zhou Jie Guan Huaqing Xie | 2013 | Procedia - Social and Behavioral Sciences2013，，： | 3 |
| 16 | Landing site topographic mapping and rover localization for Chang’e-4 mission显示文摘This paper presents the techniques and results of landing-site topographic mapping and rover localization using orbital,descent and rover images in the Chang’e-4 mission.High-resolution maps of the landing site are generated from orbital and descent images.Local digital elevation models and digital orthophoto maps with 0.02 m resolution are generated at each waypoint.The location of the lander is determined as(177.588?E,45.457?S)using festure-matching techniques.The cross-site visual localization method is routinely used to localize the rover at each waypoint to reduce error accumulation from wheel slippage and IMU drift in dead reckoning.After the first five lunar days,the rover travels 186.66 m from the lander,according to the cross-site visual localization.The developed methods and results have been directly utilized to support the mission’s operations.The maps and localization information are also valuable for supporting multiple scientific explorations of the landing site. | Zhaoqin LIU Kaichang DI Jian LI Jianfeng XIE Xiaofeng CUI Luhua XI Wenhui WAN Man PENG Bin LIU Yexin WANG Sheng GOU Zongyu YUE Tianyi YU Lichun LI Jia WANG Chuankai LIU Xin XIN Mengna JIA Zheng BO Jia LIU Runzhi WANG Shengli NIU Kuan ZHANG Yi YOU Bing LIU Jiangang LIU | 2020 | Science China(Information Sciences)2020，63，4： | 3 |
| 17 | Application of automatic surface inspection system in cold-rolled strip production显示文摘The detection and classification of real-time surface defects play an important role in automotive sheet inspection and production. In this paper,an automatic surface inspection system( ASIS) based on signal processing in Baosteel NO. 4 cold-rolled plant is briefly presented. We demonstrate that the strip surface defect properties such as image,type,pitch,and position can be accurately calculated and classified by the automatic surface inspection system.In the manufacturing of the high-quality cold-rolled strips,it is necessary that the real-time surface defects can be detected and transferred by the automatic surface inspection system combined with annealing lines and recoiling lines. | HE Jianfeng SU Yuan XIE Xianlong CAI Heng HE Chunlai | 2015 | Baosteel Technical Research2015，9，1： | 2 |
| 18 | Ore-Forming Fluids Characteristics and Metallogenesis of the Anjing Hitam Pb-Zn Deposit in Northern Sumatra, Indonesia显示文摘The Anjing Hitam Pb-Zn deposit in northern Sumatra(Indonesia) is one of the largest Pb-Zn deposits in the region. The stratiform orebodies are mainly hosted in the middle member of the Carboniferous–Permian Kluet Formation of the Tapanuli Group. Mineral paragenesis and crosscutting relationships suggest a two-stage Pb-Zn mineralization:(I) sedimentary and(Ⅱ) hydrothermal mineralization. Ore-related calcite from both stages Ⅰ and Ⅱ contains mainly liquid-and gas-liquid two-phase-type fluid inclusions(FI). For stage I ore-forming fluids, FI homogenization temperatures(T_h) are 105 to 199 oC, and the salinities are 9.6 wt.% to 16.6 wt.% NaCleqiv, reflecting low temperature and medium-low salinity; whereas in stage Ⅱ, the T_h(206 to 267 oC) and salinity(19.0 wt.% to 22.5 wt.% NaCleqiv) are considerably higher. Fluid inclusion and C-O isotope characteristics suggest that the stage I ore-forming fluids were mainly derived from a mixture of seawater and magmatic fluids(probably from deep-lying plutons), whereas the stage Ⅱ ore-forming fluids were likely magmatic-derived with wall rock input. We propose that the Anjing Hitam deposit was a Carboniferous exhalative sedimentary(SEDEX) deposit overprinted by the Pleistocene vein-style magmatic-hydrothermal mineralization. | Chaowen Huang Gaofeng Du Huajun Jiang Jianfeng Xie Daohan Zha Huan Li Chun-Kit Lai | 2019 | Journal of Earth Science2019，30，1： | 2 |
| 19 | Mechanical ventilation in acute respiratory distress syndrome: past, present and future显示文摘Acute respiratory distress syndrome (ARDS) is a life threatening respiratory failure due to lung injury from a variety of precipitants.Mechanical ventilation (MV) is the foundation in the supportive management of patients with ARDS.1 However,it is associated with several complications,such as increased risk of pneumonia and development of lung injury.The improved understanding of ARDS and complications from MV has been considered important in designing lung-protective ventilatory strategies aimed at attenuating or preventing organ dysfunction and improving outcomes. | Xie Jianfeng Qiu Haibo | 2014 | Chinese Medical Journal2014，，10： | 2 |
| 20 | Association between diacylglycerol kinase kappa variants and hypospadias susceptibility in a Han Chinese population显示文摘以前的染色体宽的协会研究在基因在欧洲降下的人口与 hypospadias 联系了的 diacylglycerol kinase kappa (DGKK ) 识别了变体。然而, DGKK 的变体都没被证实在一张最近的汉中国学习人口与 hypospadias 被联系,由于在分析包括的单个核苷酸的多型性(SNP ) 的有限数字可能。在这研究,我们试图探讨不一致的结果并且通过 DGKK 变体的更全面的分析在汉中国人口评估在 DGKK 和 hypospadias 之间的协会。我们在 322 个盒子之中与 hypospadias DGKK 为 17 SNP 进行了协会分析在或下游地(58 温和, 113 节制, 128 严重,并且 23 未知) 并且 1008 控制。在 DGKK 的五 SNP (rs2211122, rs4554617, rs7058226, rs7063116,和 rs5915254 ) 显著地与 hypospadias 被联系(P < 0.05 ) ,与 1.64-1.76 的机会比率(ORs ) 。当仅仅温和、中等的盒子与控制相比时,在 DGKK 的 10 SNP 是重要的(P < 0.05 ) ,与 1.56-2.13 的 ORs。当仅仅严重的盒子与控制相比时,没有重要 SNP 被观察。这研究成功地含有在 hypospadias 的 DGKK 变体在一张汉中国人口之中冒险,特别为温和 / 中等的盒子。hypospadias 的严重形式由于另外的基因因素是可能的。 | Hua Xie Xiao-Ling Lin Song Zhang Ling Yu Xiao-Xi Li Yi-Chen Huang Yi-Qing Lyu Hai-Tao Chen Jianfeng Xu Fang Chen | 2018 | Asian Journal of Andrology2018，20，1： | 2 |
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