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| 1 | Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination显示文摘 | Yiqiang Cui Yuyu Niu Jiankui Zhou Yongchang Chen Yiwei Cheng Shangang Li Zongyong Ai Chu Chu Hong Wang Bo Zheng Xuejin Chen Jiahao Sha Xuejiang Guo Xingxu Huang Weizhi Ji | 2018 | Cell Research2018，28，3： | 13 |
| 2 | The first observation of the atmospheric tides in the mesosphere and lower thermosphere over Hainan, China显示文摘Fuke (19.5°N, 109.1°E) meteor radar is the first radar of the low latitudes of China, which is used to detect the wind in the meso- sphere and lower thermosphere. In this paper, by using the wind data near three months (1 February-20 April, 2009), we first present the variation of the atmospheric diurnal tide, semidiurnal tide and mean wind in the height range 80-100 km over the low latitudes of China. The results from our analysis are summarized below. During spring months, there are quite strong tides in the mesopause region of Fuke. The diurnal tidal amplitude is significantly larger than the amplitude of semidiurnal tide, and the maximum amplitude (about 100 m/s) of diurnal tide appear in the meridional wind. The vertical phases of both diurnal tide and semidiurnal tide propagate downward. In addition, the observed tides are compared with the linear tide model (Global Scale Wave Model, GSWM02), and the results show that Fuke diurnal tide agrees well with the model, but there are many differences between Fuke semidiurnal tide and the results from model. | JIANG GuoYing XU JiYao SHI JianKui YANG GuoTao WANG Xiao YAN ChunXiao | 2010 | Chinese Science Bulletin2010，55，11： | 12 |
| 3 | A study of hydrate plug formation in a subsea natural gas pipeline using a novel high-pressure flow loop显示文摘The natural gas pipeline from Platform QK18-1 in the southwest of Bohai Bay to the onshore processing facility is a subsea wet gas pipeline exposed to high pressure and low temperature for a long distance. Blockages in the pipeline occur occasionally. To maintain the natural gas flow in the pipeline, we proposed a method for analyzing blockages and ascribed them to the hydrate formation and agglomeration. A new high-pressure flow loop was developed to investigate hydrate plug formation and hydrate particle size, using a mixture of diesel oil, water, and natural gas as experimental fluids. The influences of pressure and initial flow rate were also studied. Experimental results indicated that when the flow rate was below 850 kg/h, gas hydrates would form and then plug the pipeline, even at a low water content (10%) of a water/oil emulsion. Furthermore, some practical suggestions were made for daily management of the subsea pipeline. | Li Wenqing Gong Jing Lü Xiaofang Zhao Jiankui Feng Yaorong Yu Da | 2013 | Petroleum Science2013，10，1： | 11 |
| 4 | Natural gas hydrate shell model in gas-slurry pipeline flow显示文摘A hydrate shell model coupled with one-dimensional two-fluid pipe flow model was established to study the flow characteristics of gas-hydrate slurry flow system.The hydrate shell model was developed with kinetic limitations and mass transfer limitations,and it was solved by Euler method.The analysis of influence factors was performed.It was found that the diffusion coefficient was a key parameter in hydrate forming process.Considering the hydrate kinetics model and the contacting area between gas and water,the hydrate shell model was more close to its practical situations. | Jing Gong Bohui Shi Jiankui Zhao | 2010 | Journal of Natural Gas Chemistry2010，19，3： | 9 |
| 5 | The relations between density of FACs in the Plasma Sheet Boundary Layers and Kp index显示文摘We have studied 172 field-aligned currents(FACs) cases observed by the ClusterII satellites when they crossed the plasma sheet boundary layer(PSBL) in the magnetotail from July to October 2001.We mainly analyzed the relationship between the characteristic of FACs at the PSBL in magnetotail and the Kp index.The main results indicated the followings:1) In the different geomagnetic activity levels,the relative occurrence of FACs in PSBL increased monotonically with geomagnetic activity.2) The density of FACs in PSBL increased monotonically with Kp index.In the storm main phase,the density of FACs increased dramatically,the maximum FACs approximately equaled 19.05 nA m 2 while Kp equaled 5.3) The variation of FACs density in PSBL was consistent with the variation of the Kp index.However,when AE<800 nT,FACs density in PSBL increased with increasing AE,and when AE>800 nT,it decreased with increasing AE.Therefore,our results suggested that the FACs density in PSBL had a closer correlation with Kp index. | CHENG ZhengWei SHI JianKui ZHANG TieLong DUNLOP Malcolm LIU ZhenXing | 2011 | Science China(Technological Sciences)2011，54，11： | 8 |
| 6 | Observational study of daytime ionospheric irregularities associated with typhoon显示文摘Spread-F is a manifestation of ionospheric irregularities and generally takes place at nighttime. However, it can also be observed seldom at daytime. It is recognized that acoustic gravity waves (AGWs) play an important role in triggering plasma instability which results in spread-F in the ionosphere. The typhoon is a main source of the AGWs. In this paper, two cases of ionospheric daytime spread-F in the period of typhoon were analyzed. One case was on July 29, 1988 and the other was on August 01, 1989. The results showed the following: 1) There were some wave-like disturbances appearing in the HF Doppler records firstly, consequently the Doppler echo traces became scattered, which indicated that the ionospheric spread-F was triggered; 2) the blurred echo traces in the both two cases appeared in the morning (08:30-11:30 Beijing time) and lasted for more than two hours; 3) with the blurred echoes gradually weakening, the traveling ionospheric disturbances (TIDs) still existed and became clearer; 4) the frequency shifts in the two cases were both positive, implying the effective reflecting surface of the radio wave in the ionosphere moved downwards. These results provide good observational evidence for daytime spread-F during the typhoon period in Asian region. | XIAO SalGuan SHI JianKui ZHANG DongHe HAO YongQiang HUANG WeiQuan | 2012 | Science China(Technological Sciences)2012，55，5： | 6 |
| 7 | Non-smooth finite-time stabilization for a class of nonlinear systems显示文摘In this paper, global finite-time stabilization problem for a large class of nonlinear control systems is considered. An iterative design approach is given based on Lyapunov function. The finite time stabilizing control laws are constructed in the form of continuous but non-smooth time-invariant feedback. | HONG Yiguang WANG Jiankui | 2006 | Science in China(Series F)2006，49，1： | 5 |
| 8 | State and Output Feedback Finite-time Guaranteed Cost Control of Linear It Stochastic Systems显示文摘The problem of guaranteed cost control based on finite-time stability for stochastic system is first investigated in this paper.The motivation of solving this problem arises from an observation that finite/infinite-horizon guaranteed cost control does not consider the transient performance of the closed-loop system,but guaranteed cost control based on finite-time stability involves this practical requirement.In order to explain this problem explicitly,a concept of the stochastic finite-time guaranteed cost control is introduced,and then some new sufficient conditions for the existence of state and output feedback finite-time guaranteed cost controllers are derived,which guarantee finite-time stochastic stability of closed-loop systems and an upper bound of a quadratic cost function.Furthermore,this problem is reduced to a convex optimization problem with matrix inequality constraints and a new solving algorithm is given.Finally,an example is given to illustrate the effectiveness of the proposed method. | YAN Zhiguo ZHANG Guoshan WANG Jiankui ZHANG Weihai | 2015 | Journal of Systems Science & Complexity2015，28，4： | 4 |
| 9 | Variation of dependence of the cusp location at different altitude on the dipole tilt显示文摘Using the Cluster cusp crossings data,dependence of the cusp location at the mid-altitude on the geomagnetic dipole tilt during northward IMF is studied.The results show that the cusp center moves 0.051°Invariant Latitude(ILAT)upon the increase of 1°in the dipole tilt angle at the average altitude of 5.8 RE(Earth radius).According to the present results obtained at the altitude of the Cluster orbit and previous results obtained at other altitudes of other satellite orbits,it is found that the higher the altitude in the cusp region is,the bigger the dependence of cusp location on the dipole tilt angle will be.If the altitude increases by 1 RE in the cusp region,the dependence will increase by 0.012°ILAT upon the increase of 1°in the dipole tilt angle.Some possible physical mechanisms are discussed and it shows that the cusp location will be more sensitive to the solar wind dynamic pressure if the altitude is high. | GUO JianGuang SHI JianKui CHENG ZhengWei ZHANG ZiYing WANG Zheng ZHANG TieLong LIU ZhenXing DUNLOP Malcolm | 2013 | Chinese Science Bulletin2013，58，28： | 3 |
| 10 | Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos显示文摘 | Yuyu Niu Bin Shen Yiqiang Cui Yongchang Chen Jianying Wang Lei Wang Yu Kang Xiaoyang Zhao Wei Si Wei Li Andy Peng Xiang Jiankui Zhou Xuejiang Guo Ye Bi Chenyang Si Bian Hu Guoying Dong Hong Wang Zuomin Zhou Tianqing Li Tao Tan Xiuqiong Pu Fang Wang Shaohu | 2014 | Cell2014，，： | 3 |
| 11 | The correlations of ions density with geomagnetic activity and solar dynamic pressure in cusp region显示文摘A statistical study of the properties of ions (O+, He+ and H+) measured by the Cluster-II in cusp region as a function of the solar wind dynamic pressure and geomagnetic index Kp respectively was made dur-ing the summer and fall of 2001-2003. The main results are that: (1) O+ ion density responds in a sig-nificant way to geomagnetic index Kp, and He+ ion density is not correlated with geomagnetic index Kp, both of them have a significant positive correlation with solar wind dynamic pressure; (2) H+ ion density is also observed to increase with solar wind dynamic pressure, and not correlated with geomagnetic index Kp. | GUO JianGuang SHI JianKui ZHANG TieLong LIU ZhenXing A. FAZAKERLEY H. REME I. DANDOURAS E. LUOEK | 2007 | Chinese Science Bulletin2007，52，7： | 3 |
| 12 | Genome-wide profiling of RNA editing sites in sheep显示文摘Background: The widely observed RNA-DNA differences(RDDs) have been found to be due to nucleotide alteration by RNA editing. Canonical RNA editing(i.e., A-to-I and C-to-U editing) mediated by the adenosine deaminases acting on RNA(ADAR) family and apolipoprotein B mRNA editing catalytic polypeptide-like(APOBEC)family during the transcriptional process is considered common and essential for the development of an individual.To date, an increasing number of RNA editing sites have been reported in human, rodents, and some farm animals;however, genome-wide detection of RNA editing events in sheep has not been reported. The aim of this study was to identify RNA editing events in sheep by comparing the RNA-seq and DNA-seq data from three biological replicates of the kidney and spleen tissues.Results: A total of 607 and 994 common edited sites within the three biological replicates were identified in the ovine kidney and spleen, respectively. Many of the RDDs were specific to an individual. The RNA editing-related genes identified in the present study might be evolved for specific biological functions in sheep, such as structural constituent of the cytoskeleton and microtubule-based processes. Furthermore, the edited sites found in the ovine BLCAP and NEIL1 genes are in line with those in previous reports on the porcine and human homologs, suggesting the existence of evolutionarily conserved RNA editing sites and they may play an important role in the structure and function of genes.Conclusions: Our study is the first to investigate RNA editing events in sheep. We screened out 607 and 994 RNA editing sites in three biological replicates of the ovine kidney and spleen and annotated 164 and 247 genes in the kidney and spleen, respectively. The gene function and conservation analysis of these RNA editing-related genes suggest that RNA editing is associated with important gene function in sheep. The putative functionally important RNA editing sites reported in the present study will help future studies on the relationship between these edited sites and the genetic traits in sheep. | Yuanyuan Zhang Deping Han Xianggui Dong Jiankui Wang Jianfei Chen Yanzhu Yao Hesham Y.A.Darwish Wansheng Liu Xuemei Deng | 2019 | Journal of Animal Science and Biotechnology2019，10，2： | 2 |
| 13 | Application of positron emission tomography/computed tomography in radiation treatment planning for head and neck cancers显示文摘18-fluorodeoxygluocose positron emission tomography/computed tomography(18FDG-PET/CT) provides significant information in multiple settings in the management of head and neck cancers(HNC). This article seeks to define the additional benefit of PET/CT as related to radiation treatment planning for squamous cell carcinomas(SCCs) of the head and neck through a review of relevant literature. By helping further define both primary and nodal volumes, radiation treatment planning can be improved using PET/CT. Special attention is paid to the independent benefit of PET/CT in targeting mucosal primaries as well as in detecting nodal metastases. The utility of PET/CT is also explored for treatment planning in the setting of SCC of unknown primary as PET/CT may help define a mucosal target volume by guiding biopsies for examination under anesthesia thus changing the treatment paradigm and limiting the extent of therapy. Implications of the use of PET/CT for proper target delineation in patients with artifact from dental procedures are discussed and the impact of dental artifact on CT-based PET attenuation correction is assessed. Finally, comment is made upon the role of PET/CT in the high-risk post-operative setting, particularly in the context of radiation dose escalation. Real case examples are used in these settings to elucidate the practical benefits of PET/CT as related to radiation treatment planning in HNCs. | Musaddiq J Awan Farzan Siddiqui David Schwartz Jiankui Yuan Mitchell Machtay Min Yao | 2015 | World Journal of Radiology2015，7，11： | 2 |
| 14 | Detection of weak target for MIMO radar based on Hough transform显示文摘An effective method of multiple input multiple output (MIMO) radar weak target detection is proposed based on the Hough transform. The detection time duration is divided into multiple coherent processing intervals (CPIs). Within each CPI, conventional methods such as fast Fourier transform (FFT) is exploit to coherent integrating in same range cell. Furthermore, noncoherent integration through several range cells can be implemented by Hough transform among all CPIs. Thus, higher integration gain can be obtained. Simulation results are also given to demonstrate that the detection performance of weak moving target can be dramatically improved. | Zeng Jiankui He Zishu | 2009 | Journal of Systems Engineering and Electronics2009，20，1： | 2 |
| 15 | Isolation and rapid genetic characterization of a novel T4-like bacteriophage显示文摘无所不在在地球上,抗菌素是在每个生态系统,而是他们的人的知识的最丰富的实体仍然关于有机体的另外的形式与那相比被限制。充实人的知识并且支持抗菌素的利用,孤立并且描绘尽可能许多不同抗菌素是必要的。这里,我们为它的基因描述描述象 T4 一样抗菌素 IME08 和一个快速的方法的隔离。与这个方法,我们容易克隆抗菌素染色体的一些随机的碎片。这些随机的克隆的顺序分析证明抗菌素 IME08 与象 T4 一样 Enterobacteria 分享了最高的顺序类似噬菌体 T4 (94% 身份) , JS98 (95% 身份) , JS10 (95% 身份) 和 RB14 (94% 身份) 分别地,它建议 IME08 属于象 T4 一样抗菌素类。 | Wang Sheng Jiang Huanhuan Chen Jiankui Liu Dabin Li Cun Pan Bo An Xiaoping Zhang Xin Zhou Yusen Tong Yigang | 2010 | Journal of Medical Colleges of PLA(China)2010，25，6： | 2 |
| 16 | Finite Time Consensus Problem for Multiple Non-Holonomic Agents with Communication Delay显示文摘In this paper, finite time consensus problem is discussed for multiple non-holonomic mobile agents with constant communication delay. The objective is to design non-smooth distributed control laws such that multiple non-holonomic mobile agents can be all in agreement within any given finite time larger than communication delay. The authors propose a novel switching control strategy with the help of Lyapunov-based method and graph theory. | WANG Jiankui FU Jiankuan ZHANG Guoshan | 2015 | Journal of Systems Science & Complexity2015，28，3： | 2 |
| 17 | Synthesis and cladding of Al2O3 ceramic coatings on steel substrates by a laser controlled thermite reaction显示文摘 | Yanxiang Li Jiankui Yao Yuan Liu | 2003 | Surface and Coatings Technology2003，172，1： | 1 |
| 18 | Some properties of field-aligned electron events in high-altitude polar regions显示文摘Using data from the Cluster spacecraft from January 2003 to December 2004, we perform a statistical study on some properties of the field-aligned electron(FAE) events and interplanetary magnetic field(IMF) By dependence of FAE events with different durations in high-altitude polar regions. A total of 1335 FAE events were observed by the C3 spacecraft. More down-flowing events were observed in the Southern Hemisphere, and more up-flowing events were observed in the Northern Hemisphere. It proves that down-flowing events mainly originate from magnetosphere or solar wind and up-flowing events are mainly derived from ionosphere. Short-lifetime events showed a morning concentration in the magnetic local time distribution, and long-lifetime events were concentrated both before and after noon. For the IMF By dependence of the FAE events, short-lifetime events were much affected by IMF By and resulted in a morning concentration, while the long-lifetime events were almost unaffected by IMF By. With further analysis, we determined that the short-lifetime and long-lifetime events had different sources. | ZHANG ZiYing SHI JianKui ZHOU MingQuan CHENG ZhengWei ZHOU Hua | 2016 | Science China Earth Sciences2016，59，2： | 1 |
| 19 | A New Four-Wing Chaotic System and Its Unified Generalized Projective Synchronization显示文摘In this paper,some basic properties of a new four-dimensional(4 D)continuous autonomous chaotic system,in which each equation contains a cubic cross-product term,are further analyzed.The new system has 9 equilibria displaying graceful symmetry with respect to the origin and coordinate planes,and the stability of them are discussed.Then detailed bifurcation analysis is given to demonstrate the evolution processes of the system.Numerical simulations show that the system evolves chaotic motions through period-doubling bifurcation or intermittence chaos while the system parameters vary.We design a new scheme of generalized projective synchronization,so-called unified generalized projective synchronization,whose response signal synchronizes with the linear combination of drive signal.The design has the advantages of containing complete synchronization,anti-synchronization and disorder synchronization over the usual generalized projective synchronization,such that it can provide greater security in secure communication.Based on Lyapunov stability theorem,some sufficient conditions for the new synchronization are inferred.Numerical simulations demonstrate the effectiveness and feasibility of the method by employing the four-wing chaotic system. | ZHANG Li PENG Jiankui | 2020 | Wuhan University Journal of Natural Sciences2020，25，3： | 1 |
| 20 | On (m,w)-Derivations of Some Algebras 显示文摘 | SHEN Qihua LI Jiankui GUO Jianbin | 2014 | Demonstratio Math2014，47，3： | 1 |
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