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| 1 | Mapping of qGL7-2, a grain length QTL on chromosome 7 of rice显示文摘剩余在米饭染色体上带在二 SSR loci RM11 和 RM134 之间的一个异质接合的片断的异质接合的线(RHL ) 7 从一套 recombinant 被选择从生气 D50 (javanica )/HB277 (indica ) 的生来的线。以前的父母比后者生产长得多的谷物。这种选择的 Selfed 子孙 genotypically 被分析(SSR ) 并且 phenotypically (谷物长度) 。谷物长度在印射的人口是不连续地可变的,允许在 4.8 厘米间隔以内的这 QTL qGL7-2 的放置由 RM351 和 RM234 定义。在这个区域以内的一套新标记被开发,它把 QTL 缩小了到标记 Indel1 和 RM21945 定义的 278 kb 区域。这个区域包含 49 预言的基因。结果也建议为谷物长度的新奇等位基因将被用于标记的应用程序为谷物长度的改进的帮助选择。 | Gaoneng Shao Shaoqing Tang Ju Luo Guiai Jiao Xiangjin Wei Ao Tang Jianli Wu Jieyun Zhuang Peisong Hu | 2010 | Journal of Genetics and Genomics2010，37，8： | 28 |
| 2 | Effects of dietary yeast nucleotides on growth, non-specific immunity intestine growth and intestinal microbiota of juvenile hybrid tilapia Oreochromis niloticus ♀ × Oreochromis aureus ♂显示文摘This study investigated the effect of dietary supplementation of yeast nucleotides on the growth, nonspecific immunity, intestine growth and intestinal microbiota of juvenile hybrid tilapia. Tilapia(initial average weight of 8.02 g) was fed test diets supplemented with a yeast-originated nucleotide mixture(0,0.15, 0.30, 0.60, and 1.20 g/100 g diet) for 8 weeks. Fish fed the diet with 0.60% nucleotide had significantly higher weight gain than the control group(P < 0.05). Feed efficiency was improved in the fish fed 0.60 and 1.20% nucleotide compared with that in the control group. The optimal doses of nucleotides supplementation for growth and feed efficiency of fish were determined as 0.63 and 0.81%, respectively.Intestinal growth was improved in the 0.30 and 0.60% groups, as indicated by significant increase in intestine length. The fish fed 0.60 and 1.20% nucleotide showed higher super oxide dismutase(SOD)activity and lower malondialdehyde(MDA) level in the liver than the control fish, indicating enhancement of the anti-oxidant status. Serum lysozyme activity was significantly increased in the 0.15 and 0.3%nucleotide supplementation groups, suggesting an enhancement effect on the non-specific immune response. Lastly, dietary nucleotides supplementation exerted moderate influence on the intestinal microbiota of hybrid tilapia. A reduction in the cumulative abundance of putative butyrate-producing species was observed in the intestinal microbiota of fish fed diets with 0.60% nucleotide compared with the control, implying an interaction between dietary nucleotides and butyrate production. Briefly, dietary supplementation with 0.60% nucleotide improve the growth performance, immune activity and intestine growth in tilapia. | Li Xu Chao Ran Suxu He Jianli Zhang Jun Hu Yalin Yang Zhenyu Du Yanou Yang Zhigang Zhou | 2015 | Animal Nutrition2015，，3： | 12 |
| 3 | Salmeterol attenuates the inflammatory response in asthma and decreases the pro-inflammatory cytokine secretion of dendritic cells显示文摘Salmeterol 是长行动的 β激活 adenylate cyclase 的 2 收缩筋,引起长持续的 bronchodilation 并且被用于许多年到控制气喘。然而,很少信息都不关于 salmeterol 的 immunoregulatory 效果是可得到的。我们发现 salmeterol 减少在表示了肿瘤坏死 factor-alpha, interleukin-1 和 interleukin-6 的质问变应原的老鼠的一个模型的支持 inflammatory cytokines 的生产。树枝状的房间(DC ) 是介绍抗原的房间并且在航线充当哨兵。我们发现了那 salmeterol (10 −5 mol/l ) 减少了 lipopolysaccharide 引起的发炎(0.1 µ g/ml ) 在激活的鼠科的骨头导出髓的 DC。而且,西方的污点证明这保护的效果被禁止通过原子 factor-kappa B 发信号部分调停(NF-κ B ) ,激活 mitogen 的蛋白质 kinase (MAPK ) 小径和津贴的戏剧性地减少的层次。我们建议 salmeterol 由 modulating DC 调整导致变应原的气喘的发炎。在结论,我们提供 DC 是为对气喘的 salmeterol 的行动负责的目标免疫者房间的证据。 | Zhenli Hu Ruohua Chen Zhijian Cai Lei Yu Yang Fei Lixia Weng Jinghan Wang Xiahui Ge Tianyi Zhu Jianli Wang Chong Bai | 2012 | Cellular & Molecular Immunology2012，9，3： | 8 |
| 4 | RhoA as a target to promote neuronal survival and axon regeneration显示文摘Paralysis following spinal cord injury(SCI) is due to failure of axonal regeneration. It is believed that the capacities of neurons to regrow their axons are due partly to their intrinsic characteristics, which in turn are greatly influenced by several types of inhibitory molecules that are present, or even increased in the extracellular environment of the injured spinal cord. Many of these inhibitory molecules have been studied extensively in recent years. It has been suggested that the small GTPase Rho A is an intracellular convergence point for signaling by these extracellular inhibitory molecules, but due to the complexity of the central nervous system(CNS) in mammals, and the limitation of pharmacological tools, the specific roles of Rho A are unclear. By exploiting the anatomical and technical advantages of the lamprey CNS, we recently demonstrated that Rho A knockdown promotes true axon regeneration through the lesion site after SCI. In addition, we found that Rho A knockdown protects the large, identified reticulospinal neurons from apoptosis after their axons were axotomized in spinal cord. Therefore, manipulation of the Rho A signaling pathway may be an important approach in the development of treatments that are both neuroprotective and axon regeneration-promoting, to enhance functional recovery after SCI. | Jianli Hu Michael E. Seizer | 2017 | Neural Regeneration Research2017，12，4： | 4 |
| 5 | Improvement of X-Band Polarization Radar Melting Layer Recognition by the Bayesian Method and ITS Impact on Hydrometeor Classification显示文摘Using melting layer(ML)and non-melting layer(NML)data observed with the X-band dual linear polarization Doppler weather radar(X-POL)in Shunyi,Beijing,the reflectivity(ZH),differential reflectivity(ZDR),and correlation coefficient(CC)in the ML and NML are obtained in several stable precipitation processes.The prior probability density distributions(PDDs)of the ZH,ZDR and CC are calculated first,and then the probabilities of ZH,ZDR and CC at each radar gate are determined(PBB in the ML and PNB in the NML)by the Bayesian method.When PBB>PNB the gate belongs to the ML,and when PBBPNB the gate belongs to the ML,and when PBB | Jianli MA Zhiqun HU Meilin YANG Siteng LI | 2020 | Advances in Atmospheric Sciences2020，37，1： | 4 |
| 6 | Ordered mesoporous NiFe_2O_4 with ultrathin framework for low-ppb toluene sensing显示文摘Highly sensitive and selective detection against specific target gases,especially at low-ppb(part per billion)level,remain a great number of challenges in gas sensor applications.In this paper,we first present an ordered mesoporous NiFe_2O_4 for highly sensitive and selective detection against low-ppb toluene.A series of mesoporous NiFe_2O_4 materials were synthesized by templating from mesoporous silica KIT-6 and its framework thickness was reduced from 8.5 to 5 nm by varying the pore size of KIT-6 from 9.4 to 5.6 nm,accompanied with the increase of the specific surface area from 134 to 216 m^2g^(-1).The ordered mesoporous NiFe_2O_4 with both ultrathin framework of 5 nm and large specific surface area of up to 216 m^2g^(-1)exhibits a highest response(R_(gas)/R_(air)-1=77.3)toward 1,000 ppb toluene at 230℃ and is nearly 7.3 and 76.7 times higher than those for the NiFe_2O_4 replica with thick framework and its bulk counterpart respectively,which also possesses a quite low limit of detection(<2 ppb),and good selectivity. | Xiaoyong Lai Kun Cao Guoxin Shen Ping Xue Dan Wang Fang Hu Jianli Zhang Qingfeng Yang Xiaozhong Wang | 2018 | Science Bulletin2018，63，3： | 3 |
| 7 | Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia显示文摘Dear Editor,Schizophrenia is a chronic and debilitating brain disorder,which has a strong genetic component with heritability ranging from 66%to 85%[1,2].Currently,antipsychotic drugs remain the most effective treatment for the psychotic symptoms of schizophrenia[3].Because of the severe sideeffects of first-generation antipsychotics(FGAs),secondgeneration antipsychotics(SGAs)have become more widely used in the treatment of schizophrenia. | Liansheng Zhao Huijuan Wang Yamin Zhang Jinxue Wei Peiyan Ni Hongyan Ren Gang Li Qiang Wang Gavin P Reynolds Weihua Yue Wei Deng Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Yinfei Li Hua Yu Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Jeremy Coid Dai Zhang Chao Chen Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Neuroscience Bulletin2019，35，6： | 3 |
| 8 | Si-substrate LEDs with multiple superlattice interlayers for beyond 24 Gbps visible light communication显示文摘High-speed visible light communication(VLC)using light-emitting diodes(LEDs)is a potential complementary technology for beyond-5 G wireless communication networks.The speed of VLC systems significantly depends on the quality of LEDs,and thus various novel LEDs with enhanced VLC performance increasingly emerge.Among them,In Ga N/Ga N-based LEDs on a Si-substrate are a promising LED transmitter that has enabled VLC data rates beyond 10 Gbps.The optimization on the period number of superlattice interlayer(SL),which is a stressrelief epitaxial layer in a Si-substrate LED,has been demonstrated to be an effective method to improve Si-substrate LED’s luminescence properties.However,this method to improve LED’s VLC properties is barely investigated.Hence,we for the first time experimentally studied the impact of SL period number on VLC performance.Accordingly,we designed and fabricated an integrated 4×4 multichromatic Si-substrate wavelength-divisionmultiplexing LED array chip with optimal SL period number.This chip allows up to 24.25 Gbps/1.2 m VLC transmission using eight wavelengths,which is the highest VLC data rate for an In Ga N/Ga N LED-based VLC system to the best of our knowledge.Additionally,a record-breaking data rate of 2.02 Gbps over a 20-m VLC link is achieved using a blue Si-substrate LED with the optimal SL period number.These results validate the effectiveness of Si-substrate LEDs for both high-speed and long-distance VLC and pave the way for Si-substrate LED design specially for high-speed VLC applications. | FANGCHEN HU SHOUQING CHEN GUOQIANG LI PENG ZOU JUNWEN ZHANG JIAN HU JIANLI ZHANG ZHIXUE HE SHAOHUA YU FENGYI JIANG NAN CHI | 2021 | Photonics Research2021，9，8： | 3 |
| 9 | Testing the role of genetic variation of the MC4R gene in Chinese population in antipsychotic-induced metabolic disturbance显示文摘Antipsychotic-induced metabolic disturbance(AIMD) is a common adverse effect of antipsychotics with genetics partly underpinning variation in susceptibility among schizophrenia patients. Melanocortin4 receptor(MC4 R) gene, one of the candidate genes for AIMD, has been under-studied in the Chinese patients. We conducted a pharmacogenetic study in a large cohort of Chinese patients with schizophrenia. In this study, we investigated the genetic variation of MC4 R in Chinese population by genotyping two SNPs(rs489693 and rs17782313) in 1,991 Chinese patients and examined association of these variants with the metabolic effects that were often observed to be related to AIMD. Metabolic measures, including body mass index(BMI), waist circumference(WC), glucose, triglyceride, high-density lipoprotein(HDL), and low-density lipoprotein(LDL) levels were assessed at baseline and after 6-week antipsychotic treatment. We found that interaction of SNP×medication status(drug-na?ve/medicated) was significantly associated with BMI, WC, and HDL change %, respectively. Both SNPs were significantly associated with baseline BMI and WC in the medicated group. Moderate association of rs489693 with WC, Triglyceride, and HDL change % were observed in the whole sample. In the drug-na?ve group, we found recessive effects of rs489693 on BMI gain more than 7%, WC and Triglyceride change %, with AA incurring more metabolic adverse effects. In conclusion, the association between rs489693 and the metabolic measures is ubiquitous but moderate. Rs17782313 is less involved in AIMD. Two SNPs confer risk of AIMD to patients treated with different antipsychotics in a similar way. | Yamin Zhang Hongyan Ren Qiang Wang Wei Deng Weihua Yue Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Dai Zhang Liansheng Zhao Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Science China(Life Sciences)2019，62，4： | 3 |
| 10 | Induction of Siglec-G by RNA Viruses Inhibits the Innate Immune Response by Promoting RIG-I Degradation显示文摘 | Weilin Chen Chaofeng Han Bin Xie Xiang Hu Qian Yu Liyun Shi Qingqing Wang Dongling Li Jianli Wang Pan Zheng Yang Liu Xuetao Cao | 2013 | Cell2013，，3： | 2 |
| 11 | Instant Messaging Worms Propagation Simulation and Countermeasures显示文摘Instant messaging (IM) has become one of the most popular online communication tools among consumer and enter- prise IM users. It provides instant message delivery, as well as convenient file transfer services. The increasing popularity and functionalities of IM programs have made it increasingly attractive for attackers, especially for worm writers. IM contact list offers worm an easy way of finding potential victims so that the worm could achieve a surprising spreading speed. This paper first pre- sents our experimental results of simulating IM worm propagation in the logical network defined by IM contact lists, which is re- ported to be a scale-free network. Then, the existing proposals for detecting and containing IM worm epidemics are discussed. At last, a new algorithm for this purpose is presented, which is based on the observation of the bi-directional nature of IM worm traffic, and its advantages and possible improvements in implementation are analyzed. The simulation results show the proposed algorithm is of significant effect on restricting IM worm propagation. | HU Huaping WEI Jianli | 2007 | Wuhan University Journal of Natural Sciences2007，12，1： | 2 |
| 12 | Carbon dioxide conversion to valuable chemical products over composite catalytic systems显示文摘This paper reports an experimental study on catalytic conversion of carbon dioxide to methanol,ethanol and acetic acid.Catalysts having different catalytic functions were synthesized and combined in different ways to enhance the selectivity to desired products.The combined catalyst system possessed the following functions:methanol synthesis,Fischer-Tropsch synthesis,water-gas-shift and hydrogenation.Results showed that the methods of integrating these catalytic functions played an important role in achieving the desired product selectivity.We speculate that if methanol synthesis sites were located adjacent to the C-C chain growth sites,the formation rate of C_2 oxygenates would be enhanced.The advantage of using a high temperature methanol catalyst PdZnAl in the combined catalyst system was demonstrated.In the presence of PdZnAl catalyst,the combined catalyst system was stable at 380°C.It was observed that,at high temperature,kinetics favored oxygenate formation.The results implied that the process can be intensified by operating at high temperature using Pd-based methanol synthesis catalyst.Steam reforming of the byproduct organics was demonstrated as a means to provide supplemental hydrogen.Preliminary process design,simulation,and economic analysis of the proposed CO_2 conversion process were carried out.Economic analysis indicates how ethanol production cost was affected by the price of CO_2 and hydrogen. | Robert A.Dagle Jianli Hu Susanne B.Jones Wayne Wilcox John G.Frye James F.White Juyuan Jiang Yong Wang | 2013 | Journal of Energy Chemistry2013，22，3： | 2 |
| 13 | TTEM:an effective trust-based topology evolution mechanism for P2P networks显示文摘 | Hu Jianli Wu Quanyuan Zhou Bin | 2008 | Journal of Communications2008，3，7： | 1 |
| 14 | Hydroisomerization and hydrocracking of n-hexadecane over a platinum-promoted sulfated zirconia catalyst显示文摘 | Keogh R A Sparks D Hu Jianli | 1994 | Energy & Fuels1994，8，： | 1 |
| 15 | Effect of radial heat conduction on effective thermal conductivity of carbon nanotube bundles显示文摘The effect of the radial heat conduction on the effective thermal conductivity of carbon nanotube(CNT) bundles is studied by the nonequilibrium molecular dynamics(NEMD) method. The hexagonal CNT bundle consists of seven(10, 10) single-walled carbon nanotubes(SWCNTs). The radial heat conduction is induced by creating the vacancy defects in some segments of the constituent CNTs. Combined with the temperature differences and the inter-tube thermal resistances at the different segments,the radial heat flow in the CNT bundle is calculated. The maximum percentage of the radial heat flow is less than 7% with the presence of four defective CNTs, while the resultant decrement of the effective thermal conductivity of the bundle is about 18%.The present results indicate that the radial heat flow can significantly diminish the axial heat conduction in the CNT bundles,which probably explains the smaller effective thermal conductivity in the CNT assemblies compared to that of the individual CNTs. | WANG JianLi SONG YaMei ZHANG YuFeng HU YuHan YIN Hang GU YunFeng XIA Re CHEN YunFei | 2018 | Science China(Technological Sciences)2018，61，12： | 1 |
| 16 | MDR1 and MDR3 genes and drug resistance to cisplatin of ovarian cancer cells 显示文摘 | REN Lirong XIAO Lan HU JianLi | 2007 | Journal of Huazhong University of Science and Technology2007，27，6： | 1 |
| 17 | Methanation of carbon dioxide by hydrogen reduction using the Sabatier process in microchannel reactors显示文摘 | BROOKS K P HU Jianli ZHU Huayang | 2007 | Chemical Engineering Science2007，62，4： | 1 |
| 18 | Activation of Adventitial Fibroblasts in the Early Stage of the Aortic Transplant Vasculopathy in Rat显示文摘 | Jian Ji Fang Xu Li Li Rong Chen Jianli Wang Wei-cheng Hu | 2010 | Transplantation2010，，8： | 1 |
| 19 | Induction of Siglec-G by RNA Viruses Inhibits the Innate Immune Response by Promoting RIG-I Degradation显示文摘 | Weilin Chen Chaofeng Han Bin Xie Xiang Hu Qian Yu Liyun Shi Qingqing Wang Dongling Li Jianli Wang Pan Zheng Yang Liu Xuetao Cao | 2013 | Cell2013，，3： | 1 |
| 20 | Inhibition of central axon regeneration: perspective from chondroitin sulfate proteoglycans in lamprey spinal cord injury显示文摘Background:Failure of axon regeneration after spinal cord injury(SCI)underlies the paralysis that so profoundly affects patients’quality of life.Many factors are involved in the regeneration failure.Chondroitin sulfate proteoglycans(CSPGs),normal constituents of the perineuronal nets in central nervous system(CNS),are secreted at the injury site and initially were thought to act as a purely physical barrier.In the past decade,the receptor-like protein tyrosine phosphatases,protein tyrosine phosphatase sigma(PTPσ),and leukocyte common antigen-related phosphatase(LAR),have been identified as transmembrane receptors for CSPGs.The two receptors for myelin-associated growth inhibitors,Nogo receptors 1 and 3(NgR1 and NgR3)also have been found to bind with CSPGs(Sharma et al.,2012).These findings suggest that CSPGs inhibit regeneration by interacting with these receptors,initiating downstream inhibitory signaling(Figure 1). | Jianli Hu Li-Qing Jin Michael E.Selzer | 2022 | Neural Regeneration Research2022，17，9： | 1 |
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