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| 1 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 2 | The Medium Energy X-ray telescope (ME) onboard the Insight-HXMT astronomy satellite显示文摘The Medium Energy X-ray telescope(ME) is one of the three main telescopes on board the Insight hard X-ray modulation telescope(Insight-HXMT) astronomy satellite. ME contains 1728 pixels of Si-PIN detectors sensitive in 5-30 ke V with a total geometrical area of 952 cm^2. The application specific integrated circuit(ASIC) chip, VA32TA6, is used to achieve low power consumption and low readout noise. The collimators define three kinds of field of views(FOVs) for the telescope, 1°×4°, 4°×4°,and blocked ones. Combination of such FOVs can be used to estimate the in-orbit X-ray and particle background components.The energy resolution of ME is ~3 ke V at 17.8 ke V(FWHM) and the time resolution is 255 μs. In this paper, we introduce the design and performance of ME. | XueLei Cao WeiChun Jiang Bin Meng WanChang Zhang Tao Luo Sheng Yang ChunLei Zhang YuDong Gu Liang Sun XiaoJing Liu JiaWei Yang Xian Li Ying Tan ShaoZhen Liu YuanYuan Du FangJun Lu YuPeng Xu Ju Guan ShuangNan Zhang HuanYu Wang TiPei Li ChengMo Zhang XiangYang Wen JinLu Qu LiMing Song XiaoBo Li MingYu Ge YuPeng Zhou ShaoLin Xiong Shu Zhang YongJie Zhang ZeHao Cheng Fei Zhang MaoShun Li XiaoHua Liang Min Gao EnBo Yang XiaoHang Liu HongWei Liu YiJung Yang Fan Zhang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 5 |
| 3 | Integrated DNA-based/biochemical screening for early diagnosis of multiple endocrine neoplasia type 2A (MEN2A)显示文摘Multiple endocrine neoplasia type 2A (MEN2A), a subtype of MEN2, is characterized by medullary thyroid cancer, pheochromocytoma, and primary hyperparathyroidism. A Han Chinese pedigree with MEN2A was investigated following confirmation of the proband's diagnosis by pathological findings and DNA/biochemical screening. DNA samples from 4 other family members were collected and exon 5, 8, 10, 11, 13, 16 and 18 of the RET proto-oncogene were sequenced and then analyzed. A missense mutation of TGG (Trp) to TGC (Cys) at codon 634 (the classic MEN2A mutation) in exon 11 of the RET gene was detected in 3 family members, including the proband. Sequencing data were compared with the human gene mutation database. Elevated serum calcitonin level was detected initially; medullary thyroid carcinoma was revealed in the 3 cases and adrenal pheochromocy-toma was also found in the proband. Elective operations were successfully performed on the adrenal and thyroid glands because of pheochromocytoma and medullary thyroid carcinoma. Our case study confirms that integrated DNA-based/biochemical screening is crucial for early diagnosis of MEN2A and is helpful in the screening of their relatives. In addition, DNA-based screening may occasionally uncover a previously unknown RET sequence. | Qin Cui Wen Wang Zhenzhen Fu Xin Shao Zhihong Zhang Mei Zhang Xianxia Ju Kunlin Wang Jiawei Chen Hongwen Zhou | 2013 | The Journal of Biomedical Research2013，27，2： | 3 |
| 4 | Utilization of aluminum hydroxide waste generated in fluoride adsorption and coagulation processes for adsorptive removal of cadmium ion显示文摘尽管基于 Al 的凝结和吸附过程为氟化物(F) 移动被证明高度有效,二个过程两个都产生大量艾尔(哦)3 固体废物包含 F (艾尔(哦)3-F) 。这研究试图调查利用艾尔的可行性(哦) 在艾尔产生的 3-F (哦)3 吸附(艾尔(哦)3-F 广告 ) 和凝结(艾尔(哦)3-F 为镉离子(Cd (II )) 的吸附的 coag ) 。艾尔的吸附能力(哦)3-F 广告 和艾尔(哦)3-F 为 Cd (II ) 的 coag 作为太古的铝氢氧化物的类似(艾尔(哦) 具有 24.39 和 19.90 mg 映慬Р的 3), | Jiawei JU Ruiping LIU Zan HE Huijuan LIU Xiwang ZHANG Jiuhui QU | 2016 | Frontiers of Environmental Science & Engineering2016，10，3： | 2 |
| 5 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 6 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 7 | Effects of fluoride on the removal of cadmium and phosphate by aluminum coagulation显示文摘This study focuses on the effects of p H and fluoride at different molar ratios of fluoride to Al(R F:Al) on the removal of cadmium(Cd^(2+)) and phosphate by Al coagulation. Fluoride at R F:Al≥ 3:1 inhibits the removal of Cd over wide Al dose ranges from 5 to 10 mg/L as Al. The removal of phosphate decreases significantly at high R F:Al of 10:1 whereas at lowered R F:Al(i.e., ≤ 6:1), an adverse effect is observed only at insufficient Al doses below 2 mg/L. Fluoride shows inhibitive effects towards the removal of Cd at p H 7 and 8 and that of phosphate at p H 6. Fluoride decreases the ζ-potential in both systems, and the decreasing extent is positively correlated to the elevated R F:Al. The Al fluoride interactions include the formation of Al–F complexes and the adsorption of fluoride onto Al(OH)_3 precipitates, i.e., the formation of Al(OH)n F m. Al–F complex formation inhibits Al hydrolysis and increases residual Al levels, and a more significant increase was observed at lower p H. Al–F complexes at high R F:Al complicate the coagulation behavior of Al towards both negative and positive ionic species. Moreover, fluoride at low R F:Al shows little effect on Al coagulation behavior towards Cd^(2+)and phosphate, and the spent defluoridation adsorbent,i.e., aluminum(Al) hydro(oxide) with adsorbed fluoride at R F:Al of below 0.1:1, may be reclaimed as a coagulant after being dissolved. | Ruiping Liu Bao Liu Lijun Zhu Zan He Jiawei Ju Huachun Lan Huijuan Liu | 2015 | Journal of Environmental Sciences2015，27，6： | 1 |
| 8 | High-energy,alignment-insensitive,injection-seeded Q-switched Ho:yttrium aluminum garnet single-frequency laser显示文摘A high-energy,alignment-insensitive,injection-seeded Q-switched Ho:yttrium aluminum garnet(YAG)singlefrequency laser is developed.Both the slave Q-switched laser and the seed laser are Ho:YAG ring lasers based on a pair of corner cubic reflectors.The seed laser has an available power of 830 mW at 2096.667 nm.At 100 Hz,the Q-switched Ho:YAG laser provides a single-frequency pulsed output using injection-seeded technology.The 7.3 mJ single-frequency pulse energy from the slave laser has a pulse width of 161.2 ns and is scaled to 33.3 mJ after passing through the Ho:YAG single-pass amplifier.According to the measurement results of the heterodyne beating technique,the single-frequency pulse has a half-width of 4.12 MHz. | Dong Yan Yue Yuan Yunpeng Wang Jiawei Fan Jiaze Wu Xiaoming Duan Sining Li Tongyu Dai Youlun Ju | 2023 | High Power Laser Science and Engineering2023，11，5： | 0 |
| 9 | Highly robust spatiotemporal wavefront prediction with a mixed graph neural network in adaptive optics显示文摘The time-delay problem,which is introduced by the response time of hardware for correction,is a critical and nonignorable problem of adaptive optics(AO)systems.It will result in significant wavefront correction errors while turbulence changes severely or system responses slowly.Predictive AO is proposed to alleviate the time-delay problem for more accurate and stable corrections in the real time-varying atmosphere.However,the existing prediction approaches either lack the ability to extract non-linear temporal features,or overlook the authenticity of spatial features during prediction,leading to poor robustness in generalization.Here,we propose a mixed graph neural network(MGNN)for spatiotemporal wavefront prediction.The MGNN introduces the Zernike polynomial and takes its inherent covariance matrix as physical constraints.It takes advantage of conventional convolutional layers and graph convolutional layers for temporal feature catch and spatial feature analysis,respectively.In particular,the graph constraints from the covariance matrix and the weight learning of the transformation matrix promote the establishment of a realistic internal spatial pattern from limited data.Furthermore,its prediction accuracy and robustness to varying unknown turbulences,including the generalization from simulation to experiment,are all discussed and verified.In experimental verification,the MGNN trained with simulated data can achieve an approximate effect of that trained with real turbulence.By comparing it with two conventional methods,the demonstrated performance of the proposed method is superior to the conventional AO in terms of root mean square error(RMS).With the prediction of the MGNN,the mean and standard deviation of RMS in the conventional AO are reduced by 54.2%and 58.6%at most,respectively.The stable prediction performance makes it suitable for wavefront predictive correction in astronomical observation,laser communication,and microscopic imaging. | JU TANG JI WU JIAWEI ZHANG MENGMENG ZHANG ZHENBO REN JIANGLEI DI LIUSEN HU GUODONG LIU JIANLIN ZHAO | 2023 | Photonics Research2023，11，11： | 0 |
| 10 | Recognition of Drivers'Hard and Soft Braking Intentions Based on Hybrid Brain-Computer Interfaces显示文摘In this paper,we propose simultaneous and sequential hybrid brain-computer interfaces(hBCIs)that incorporate electroencephalography(EEG)and electromyography(EMG)signals to dasify drivers'hard braking,soft braking,and normal driving intentions to better assist driving for the first time.The simultaneous hBCIs adopt a feature-level fusion strategy(hBCI-FL)and clasifier-level fusion strategies(hBCIs-CL).The sequential hBCIs indude the hBCI SE1,where EEG signals are prioritized to detect hard braking,and h BCI-SE2,where EMG signals are prioritized to detect hard braking.Experimental results show that the proposed hBCI-SE1 with spectral features and the one vs-rest dassification strategy performs best with an average system accuracy of 96.37%among hBCIs.This work is valuable for developing human-centric itelligent assistant driving systems to improve driving safety and driving comfort and promote the application of BCIs. | Jiawei Ju Aberham Genetu Feleke Longxi Luo Xinan Fan | 2022 | Cyborg and Bionic Systems2022，，1： | 0 |
| 11 | A Push–Pull Mechanism Helps Design Highly Competent G-Quadruplex-DNA Catalysts显示文摘Massive efforts are currently being invested to improve the performance,versatility,and scope of applications of nucleic acid catalysts.G-quadruplex(G4)/hemin DNAzymes are of particular interest owing to their structural programmability and chemical robustness.However,optimized catalytic efficiency is still bottleneck and the activation mechanism is unclear.Herein,we have designed a series of parallel G4s with different proximal cytosine(dC)derivatives to fine-tune the hemin-binding pocket for G4-DNAzymes. | Jielin Chen Jiawei Wang Stephanie C.Cvan der Lubbe Mingpan Cheng Dehui Qiu David Monchaud Jean-Louis Mergny Célia Fonseca Guerra Huangxian Ju Jun Zhou | 2021 | CCS Chemistry2021，3，8： | 0 |
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