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| 1 | Effects of pH and soil texture on the adsorption and transport of Cd in soils显示文摘To better understand the adsorption and transport of Cd2+ in soils, column experiments were conducted with various soils and inflow solutions with different pH values. Breakthrough curves (BTCs) of the column tests were fitted using both the equilibrium and non-equilibrium models installed in the program of CXTFIT. Results showed that the equilibrium model fitted most of BTCs reasonably well. Values of the retardation factor (R) and the distribution coefficient (kd) for Cd2+ adsorption and transport increased with increasing pH values of the inflow solution and of the soil. However, the clay content was not a key factor to affect R and kd for Cd2+ adsorption and transport. The average dispersivity values and the variance values of dispersivity increased with increasing clay content of the soils. | HUANG Shuang ZHANG RenDuo ZHANG JiaYing PAN Rong | 2009 | Science China(Technological Sciences)2009，52，11： | 8 |
| 2 | The precise regulation of different COR genes by individual CBF transcription factors in Arabidopsis thaliana显示文摘The transcription factors CBF1/2/3 are reported to play a dominant role in the cold responsive network of Arabidopsis by directly regulating the expression levels of cold responsive(COR) genes.In this study,we obtained CRISPR/Cas9-mediated loss-of-function mutants of cbf1$3.Over 3,000 COR genes identified by RNA-seq analysis showed a slight but significant change in their expression levels in the mutants compared to the wildtype plants after being treated at 4 °C for 12 h.The C-repeat(CRT) motif(50-CCGAC-30) was enriched in promoters of genes that were up-regulated by CBF2 and CBF3 but not in promoters of genes up-regulated by CBF1.These data suggest that CBF2 and CBF3 play a more important role in directing the cold response by regulating different sets of downstream COR genes.More than 2/3 of COR genes were co-regulated by two or three CBFs and were involved mainly in cellular signal transduction and metabolic processes;less than 1/3 of the genes were regulated by one CBF,and those genes up-regulated were enriched in cold-related abiotic stress responses.Our results indicate that CBFs play an important role in the trade-off between cold tolerance and plant growth through the precise regulation of COR genes in the complicated transcriptional network. | Yihao Shi Jiaying Huang Tianshu Sun Xuefei Wang Chenqi Zhu Yuxi Ai Hongya Gu | 2017 | Journal of Integrative Plant Biology2017，59，2： | 7 |
| 3 | Factors that determine catastrophic expenditure for tuberculosis care: a patient survey in China显示文摘Background:Tuberculosis(TB)often causes catastrophic economic effects on both the individual suffering the disease and their households.A number of studies have analyzed patient and household expenditure on TB care,but there does not appear to be any that have assessed the incidence,intensity and determinants of catastrophic health expenditure(CHE)relating to TB care in China.That will be the objective of this paper.Methods:The data used for this study were derived from the baseline survey of the China Government–Gates Foundation TB Phase Ⅱ program.Our analysis included 747 TB cases.Catastrophic health expenditure for TB care was estimated using two approaches,with households defined as experiencing CHE if their annual expenditure on TB care:(a)exceeded 10%of total household income;and(b)exceeded 40%of their non-food expenditure(capacity to pay).Chi-square tests were used to identify associated factors and logistic regression analysis to identify the determinants of CHE.Results:The incidence of CHE was 66.8%using the household income measure and 54.7%using non-food expenditure(capacity to pay).An inverse association was observed between CHE rates and household income level.Significant determinants of CHE were:age,household size,employment status,health insurance status,patient income as a percentage of total household income,hospitalization and status as a minimum living security household.Factors including gender,marital status and type of TB case had no significant associations with CHE.Conclusions:Catastrophic health expenditure incidence from TB care is high in China.An integrated policy expanding the free treatment package and ensuring universal coverage,especially the height of UHC for TB patients,is needed.Financial and social protection interventions are essential for identified at-risk groups. | Chengchao Zhou Qian Long Jiaying Chen Li Xiang Qiang Li Shenglan Tang Fei Huang Qiang Sun Henry Lucas | 2016 | Infectious Diseases of Poverty2016，5，1： | 6 |
| 4 | Thymosin Alpha-1 Inhibits Complete Freund’s Adjuvant-Induced Pain and Production of Microglia-Mediated Pro-inflammatory Cytokines in Spinal Cord显示文摘Activation of inflammatory responses regulates the transmission of pain pathways through an integrated network in the peripheral and central nervous systems.The immunopotentiator thymosin alpha-1(Tal)has recently been reported to have anti-inflammatory and neuroprotective functions in rodents.However,how Tα1 affects inflammatory pain remains unclear.In the present study,intraperitoneal injection of Tal attenuated complete Freund's adjuvant(CFA)-induced pain hypersensitivity,and decreased the up-regulation of pro-inflammatory cytokines(TNF-α,IL-1β,and IL-6)in inflamed skin and the spinal cord.We found that CFA-induced peripheral inflammation evoked strong microglial activation,but the effect was reversed by Tα1.Notably,Tα1 reversed the CFA-induced up-regulation of vesicular glutamate transporter(VGLUT)and down-regulated the vesicular γ-aminobutyric acid transporter(VGAT)in the spinal cord.Taken together,these results suggest that Tα1 plays a therapeutic role in inflammatory pain and in the modulation of microgliainduced pro-inflammatory cytokine production in addition to mediation of VGLUT and VGAT expression in the spinal cord. | Yunlong Xu Yanjun Jiang Lin Wang Jiahua Huang Junmao Wen Hang Lv Xiaoli Wu Chaofan Wan Chuanxin Yu Wenjie Zhang Jiaying Zhao Yinqi Zhou Yongjun Chen | 2019 | Neuroscience Bulletin2019，35，4： | 4 |
| 5 | The protective effects of peptides from Chinese baijiu on AAPH-induced oxidative stress in HepG2 cells via Nrf2 signaling pathway显示文摘Antioxidant peptides have been widely reported.However,only a few reports have been published examining the antioxidant peptides derived from Chinese baijiu.In this study,6 novel peptides derived from Chinese baijiu were identified successfully using high-performance liquid chromatography-quadrupoletime-of-flight mass spectrometry(HPLC-QTOF-MS)with a concentration of 0.835–24.540μg/L.The underlying molecular mechanisms were investigated,and their cytoprotective effects were examined against 2,2’-azobis(2-methylpropanimidamidine)dihydrochloride(AAPH)-induced oxidative stress in Hep G2 cells.The results showed that these peptides exerted protective effects by suppressing reactive oxygen species(ROS)generation,preventing malondialdehyde(MDA)formation,and upregulating cellular antioxidant enzyme activities(SOD,CAT,and GSH-Px)in a dose-dependent manner.Further experiments proved that these peptides exerted antioxidant effects via Nrf2/ARE-mediated signaling pathway by promoting Nrf2 nuclear translocation,inhibiting ubiquitination,and enhancing transcription capacity of Nrf2 in Hep G2 cells.These findings provide the molecular basis for the effects of antioxidant peptides derived from Chinese baijiu,which is important for a deeper understanding of the relationship between human health and moderate drinking. | Jiaying Huo Yuezhang Ming Huifeng Li Anjun Li Jiwen Zhao Mingquan Huang Weizheng Sun Jihong Wu Jinglin Zhang | 2022 | Food Science and Human Wellness2022，11，6： | 3 |
| 6 | Copy number alteration profiling facilitates differential diagnosis between ossifying fibroma and fibrous dysplasia of the jaws显示文摘Ossifying fibroma(OF)and fibrous dysplasia(FD)are two fibro-osseous lesions with overlapping clinicopathological features,making diagnosis challenging.In this study,we applied a whole-genome shallow sequencing approach to facilitate differential diagnosis via precise profiling of copy number alterations(CNAs)using minute amounts of DNA extracted from morphologically correlated microdissected tissue samples.Freshly frozen tissue specimens from OF(n=29)and FD(n=28)patients were obtained for analysis.Lesion fibrous tissues and surrounding normal tissues were obtained by laser capture microdissection(LCM),with~30–50 cells(5000–10000µm2)per sample.We found that the rate of recurrent CNAs in OF cases was much higher(44.8%,13 of 29)than that in FD cases(3.6%,1 of 28).Sixty-nine percent(9 of 13)of the CNA-containing OF cases involved segmental amplifications and deletions on Chrs 7 and 12.We also identified eight CNA-associated genes(HILPDA,CALD1,C1GALT1,MICALL2,PHF14,AIMP2,MDM2,and CDK4)with amplified expression,which was consistent with the copy number changes.We further confirmed a jaw lesion with a previous uncertain diagnosis due to its ambiguous morphological features and the absence of GNAS mutation as OF based on the typical Chr 12 amplification pattern in its CNA profile.Moreover,analysis of a set of longitudinal samples collected from an individual with a cellular lesion in suspicion of OF at the first surgery,recurrence and the latest malignant transformation revealed identical CNA patterns at the three time points,suggesting that copy number profiling can be used as an important tool to identify borderline lesions or lesions with malignant potential.Overall,CNA profiling of fibro-osseous lesions can greatly improve differential diagnosis between OF and FD and help predict disease progression. | Ming Ma Lu Liu Ruirui Shi Jianyun Zhang Xiaotian Li Xuefen Li Jiaying Bai Jianbin Wang Yanyi Huang Tiejun Li | 2021 | International Journal of Oral Science2021，13，2： | 3 |
| 7 | Novel DYW-type pentatricopeptide repeat(PPR) protein BLX controls mitochondrial RNA editing and splicing essential for early seed development of Arabidopsis显示文摘In plants, RNA editing is a post-transcriptional process that changes specific cytidine to uridine in both mitochondria and plastids. Most pentatricopeptide repeat(PPR) proteins are involved in organelle RNA editing by recognizing specific RNA sequences. We here report the functional characterization of a PPR protein from the DYW subclass, Baili Xi(BLX), which contains five PPR motifs and a DYW domain. BLX is essential for early seed development, as plants lacking the BLX gene was embryo lethal and the endosperm failed to initiate cellularization. BLX was highly expressed in the embryo and endosperm, and the BLX protein was specifically localized in mitochondria, which is essential for BLX function. We found that BLX was required for the efficient editing of 36 editing sites in mitochondria. Moreover, BLX was involved in the splicing regulation of the fourth intron of nad1 and the first intron of nad2. The loss of BLX function impaired the mitochondrial function and increased the reactive oxygen species(ROS) level. Genetic complementation with truncated variants of BLX revealed that, in addition to the DYW domain, only the fifth PPR motif was essential for BLX function. The upstream sequences of the BLX-targeted editing sites are not conserved, suggesting that BLX serves as a novel and major mitochondrial editing factor(MEF) via a new non-RNA-interacting manner. This finding provides new insights into how a DYW-type PPR protein with fewer PPR motifs regulates RNA editing in plants. | Yan Sun Jiaying Huang Sheng Zhong Hongya Gu Shan He Li-Jia Qu | 2018 | Journal of Genetics and Genomics2018，45，3： | 2 |
| 8 | Moire-pattern-modulated electronic structures in Sb_(2)Te_(3)/graphene heterostructure显示文摘Moire superlattice has recently been found in topological insulators,which can lead to periodic modulation on the electronic structure.In this work,we report the low-temperature scanning tunneling microscopy study of Sb_(2)Te_(3) films grown on graphitized 4H-SiC.We find that substrate temperature can strongly influence the rotation angles between Sb_(2)Te_(3) film and graphene substrate.Three kinds of moire patterns are observed at the first quintuple layer Sb_(2)Te_(3) film under different substrate temperatures.One shows complicated patterns with a rotation angle of nearly 0°relative to the substrate,another just exhibits simple 1 ×1 structure with a rotation angle of 30°.Other rotation angle like 8.2°is observed at higher substrate temperature as well,which is relatively rare.Comparison of the d//dV curves from Sb_(2)Te_(3) films with different moire patterns indicates that the superstructure can offer degrees of freedom in tailoring electronic structure.This work may stimulate the further study on the moire modulation to the electronic properties of topological insulators. | Yin Yin Guanyong Wang Chen Liu Haili Huang Jiayi Chen Jiaying Liu Dandan Guan Shiyong Wang Yaoyii Li Canhua Liu Hao Zheng Jinfeng Jia | 2022 | Nano Research2022，15，2： | 1 |
| 9 | Green‑Solvent Processed Blade‑Coating Organic Solar Cells with an Efficiency Approaching 19%Enabled by Alkyl‑Tailored Acceptors显示文摘Power-conversion-efficiencies(PCEs)of organic solar cells(OSCs)in laboratory,normally processed by spin-coating technology with toxic halogenated solvents,have reached over 19%.However,there is usually a marked PCE drop when the bladecoating and/or green-solvents toward large-scale printing are used instead,which hampers the practical development of OSCs.Here,a new series of N-alkyl-tailored small molecule acceptors named YR-SeNF with a same molecular main backbone are developed by combining selenium-fused central-core and naphthalene-fused endgroup.Thanks to the N-alkyl engineering,NIR-absorbing YR-SeNF series show different crystallinity,packing patterns,and miscibility with polymeric donor.The studies exhibit that the molecular packing,crystallinity,and vertical distribution of active layer morphologies are well optimized by introducing newly designed guest acceptor associated with tailored N-alkyl chains,providing the improved charge transfer dynamics and stability for the PM6:L8-BO:YRSeNF-based OSCs.As a result,a record-high PCE approaching 19%is achieved in the blade-coating OSCs fabricated from a greensolvent o-xylene with high-boiling point.Notably,ternary OSCs offer robust operating stability under maximum-power-point tracking and well-keep>80%of the initial PCEs for even over 400 h.Our alkyl-tailored guest acceptor strategy provides a unique approach to develop green-solvent and blade-coating processed high-efficiency and operating stable OSCs,which paves a way for industrial development. | Hairui Bai Ruijie Ma Wenyan Su Top Archie Dela Pea Tengfei Li Lingxiao Tang Jie Yang Bin Hu Yilin Wang Zhaozhao Bi Yueling Su Qi Wei Qiang Wu Yuwei Duan Yuxiang Li Jiaying Wu Zicheng Ding Xunfan Liao Yinjuan Huang Chao Gao Guanghao Lu Mingjie Li Weiguo Zhu Gang Li Qunping Fan Wei Ma | 2023 | Nano-Micro Letters2023，15，12： | 1 |
| 10 | Self-propagating high-temperature synthesis of TiC–TiB 2 -based Co cermets from a Co–Ti–B 4 C system and fabrication of coatings using the cermet powders显示文摘 | Binglin Zou Jiaying Xu Ying Wang Sumei Zhao Xizhi Fan Yu Hui Xin Zhou Wenzhi Huang Xiaolong Cai Shunyan Tao Hongmei Ma Xueqiang Cao | 2013 | Chemical Engineering Journal2013，，： | 1 |
| 11 | Introduction to AVS2 Scene Video Coding Techniques显示文摘The second generation Audio Video Coding Standard(AVS2) is the most recent video coding standard. By introducing several new coding techniques, AVS2 can provide more efficient compression for scene videos such as surveillance videos, conference videos,etc. Due to the limited scenes, scene videos have great redundancy especially in background region. The new scene video coding techniques applied in AVS2 mainly focus on reducing redundancy in order to achieve higher compression. This paper introduces several important AVS2 scene video coding techniques. Experimental results show that with scene video coding tools, AVS2 can save nearly 40% BD-rate(Bj?ntegaard-Delta bit-rate) on scene videos. | Jiaying Yan Siwei Dong Yonghong Tian Tiejun Huang | 2016 | ZTE Communications2016，14，1： | 1 |
| 12 | Synthesis and characterization of in situ TiC–TiB 2 composite coatings by reactive plasma spraying on a magnesium alloy显示文摘 | Binglin Zou Shunyan Tao Wenzhi Huang Zuhair S. Khan Xizhi Fan Lijian Gu Ying Wang Jiaying Xu Xiaolong Cai Hongmei Ma Xueqiang Cao | 2013 | Applied Surface Science2013，，： | 1 |
| 13 | Preparation and Analysis of Fe 3 O 4 Magnetic Nanoparticles Used as Targeted-drug Carriers * * Supported by the Technology Project of Jiangxi Provincial Education Department and Jiangxi Provincial Science Department.显示文摘 | Yuanbi ZHAO Zumin QIU Jiaying HUANG | 2008 | Chinese Journal of Chemical Engineering2008，，3： | 1 |
| 14 | Resilience patterns of human mobility in response to extreme urban floods显示文摘Large-scale disasters can disproportionately impact different population groups,causing prominent disparity and inequality,especially for the vulnerable and marginalized.Here,we investigate the resilience of human mobility under the disturbance of the unprecedented‘720’Zhengzhou flood in China in 2021 using records of 1.32 billion mobile phone signaling generated by 4.35 million people.We find that although pluvial floods can trigger mobility reductions,the overall structural dynamics of mobility networks remain relatively stable.We also find that the low levels of mobility resilience in female,adolescent and older adult groups are mainly due to their insufficient capabilities to maintain business-as-usual travel frequency during the flood.Most importantly,we reveal three types of counter-intuitive,yet widely existing,resilience patterns of human mobility(namely,‘reverse bathtub’,‘ever-increasing’and‘ever-decreasing’patterns),and demonstrate a universal mechanism of disaster-avoidance response by further corroborating that those abnormal resilience patterns are not associated with people’s gender or age.In view of the common association between travel behaviors and travelers’socio-demographic characteristics,our findings provide a caveat for scholars when disclosing disparities in human travel behaviors during flood-induced emergencies. | Junqing Tang Pengjun Zhao Zhaoya Gong Hongbo Zhao Fengjue Huang Jiaying Li Zhihe Chen Ling Yu Jun Chen | 2023 | National Science Review2023，10，8： | 1 |
| 15 | Preparation and Analysis of Fe 3 O 4 Magnetic Nanoparticles Used as Targeted-drug Carriers * * Supported by the Technology Project of Jiangxi Provincial Education Department and Jiangxi Provincial Science Department.显示文摘 | Yuanbi ZHAO Zumin QIU Jiaying HUANG | 2008 | Chinese Journal of Chemical Engineering2008，，3： | 1 |
| 16 | TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO显示文摘Sensing of pathogenic nucleic acids by pattern recognition receptors(PRR)not only initiates anti-microbe defense but causes inflammatory and autoimmune diseases.E3 ubiquitin ligase(s)critical in innate response need to be further identified.Here we report that the tripartite motif-containing E3 ubiquitin ligase TRIM41 is required to innate antiviral response through facilitating pathogenic nucleic acids-triggered signaling pathway.TRIM41 deficiency impairs the production of inflammatory cytokines and type I interferons in macrophages after transfection with nucleic acid-mimics and infection with both DNA and RNA viruses.In vivo,TRIM41 deficiency leads to impaired innate response against viruses.Mechanistically,TRIM41 directly interacts with BCL10(B cell lymphoma 10),a core component of CARD proteins-BCL10—MALT1(CBM)complex,and modifies the Lys63-linked polyubiquitylation of BCL10,which,in turn,hubs NEMO for activation of NF-kB and TANK-binding kinase 1(TBK1)—interferon regulatory factor 3(IRF3)pathways.Our study suggests that TRIM41 is the potential universal E3 ubiquitin ligase responsible for Lys63 linkage of BCL10 during innate antiviral response,adding new insight into the molecular mechanism for the control of innate antiviral response. | Zhou Yu Xuelian Li Mingjin Yang Jiaying Huang Qian Fang Jianjun Jia Zheng Li Yan Gu Taoyong Chen Xuetao Cao | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 1 |
| 17 | Similarities of Molecular Genetic Changes in Synchronous and Metachronous Colorectal Cancers Are Limited and Related to the Cancers’ Proximities to Each Other显示文摘 | Peter Zauber Jiaying Huang Marlene Sabbath-Solitare Stephen Marotta | 2013 | The Journal of Molecular Diagnostics2013，，： | 1 |
| 18 | Tobacco Rattle Virus-induced Phytoene Desaturase (PDS) Silencing in Centaurea cyanus显示文摘Virus-induced gene silencing(VIGS)is a genetic tool used to assess gene function.Tobacco rattle virus(TRV)is a VIGS vector commonly used to induce endogenous gene silencing in plants.However,there is no VIGS system established for Centaurea spp.We evaluated the effectiveness of a TRV-based VIGS system using phytoene desaturase(PDS)as a reporter gene in Centaurea cyanus.Three methods including pressure-,vacuum-and apical meristem-infiltrationwere tested to infect C.cyanus seedlings.Photobleached leaveswere only obtained using apicalmeristem-infiltration after a 14 d treatment.The CcPDS transcripts in photobleached leaves were significantly reduced compared with that in green leaves treated with empty TRV.Four C.cyanus cultivars were tested to detect their VIGS responses,and‘Dwarf Tom Pouce Blue’was the most sensitive.The agro-infiltration condition was optimized by screening for the optimal seedling stage as well as the optimum Agrobacterium density for efficient silencing.Seedlings with four true leaves and infiltration with an Agrobacterium density of OD_(600)0.5 were optimal conditions to obtain more photobleached leaves and more intense photobleached phenotype.The results demonstrated the feasibility of TRV-based VIGS for functional analysis of genes in C.cyanus. | Chengyan Deng Fan Zhang Jiaying Wang Yanfei Li He Huang Silan Dai | 2021 | Horticultural Plant Journal2021，7，2： | 1 |
| 19 | Synergistic effect of cucurbitacin B in combination with curcumin via enhancing apoptosis induction and reversing multidrug resistance in human hepatoma cells显示文摘 | Yuqi Sun Jie Zhang Jiaying Zhou Ziyuan Huang Haiyang Hu Mingxi Qiao Xiuli Zhao Dawei Chen | 2015 | European Journal of Pharmacology2015，，： | 1 |
| 20 | A Comment on the US Committee on the Present Danger显示文摘Under the Trump administration,the American hawkish think tanks and civil groups have actively revived,with the Committee on the Present Danger emerging as a representative of these hawkish civil groups nationwide.This Committee has been initiated four times in US history,and it has exerted a considerable influence on American diplomacy at critical historical moments.For a better understanding of the role played by such hawkish civil groups,as well as the featured activities involved,an analysis is performed from the following perspectives:the conditions for the development of the Committee on the Present Danger in American politics,the way it performs its roles,and its future influence.The Committee on the Present Danger,re-initiated recently,is attempting to encourage a negative attitude on the part of American populace towards China at a critical point,and this will pose certain challenges to the US-China relationship. | Zhou Xinyu Huang Jiaying | 2019 | Contemporary International Relations2019，29，6： | 0 |
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