|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Microstructure and properties of Al_2O_3-13%TiO_2 coatings sprayed using nanostructured powders显示文摘The microstructure and wear performance of Al2O3-13% TiO2 coatings prepared by plasma spraying of agglom- erated nanoparticle powders were investigated. SEM analysis showed that the as-sprayed Al2O3-TiO2 coatings comprise of two kinds of typical region: fully melted region and unmelted/partially melted nanostructured region, which is different than the conventional coating with lamellar structure. It is shown that the microhardness of the nanostructured coatings was about 15%-30% higher than that of the conventional coating and the wear resistance is significantly improved, especially under a high wear load. The nanostructured coating sprayed at a lower power shows a lower wear resistance than the coat- ings produced at a higher power, because of the presence of pores and microstructural defects which are detrimental to the fracture toughness of the coatings. | ZHANG Jianxin HE Jining DONG Yanchun LI Xiangzhi YAN Dianran | 2007 | Rare Metals2007，26，4： | 18 |
| 2 | Estimation on the Total Quantity of Biomass Energy and Its Environmental Benefit Analysis in Shandong Province显示文摘[Objective] The aim was to estimate the total quantity of biomass energy and analyze its environmental benefit in Shandong Province.[Method] Based on the data from the statistics yearbook of Shandong Province in 2010,the total quantity of biomass resources and biomass energy in Shandong Province in 2009 was estimated,and its environmental benefit was analyzed.[Result] Biomass resources in Shandong Province mainly refer to crop residues,forest residues,grassland changed from degraded land.If degraded land became grassland,the total quantity of biomass resources and biomass energy in Shandong Province in 2009 was 182.808 8 million tons and 2.68×1015 kJ respectively.Meanwhile,the reduction of total emission of CO2,SO2 and nitrogen oxides was up to 241.265 million tons,and the reduced emission of SO2 accounted for 48.9% of annual SO2 emission in Shandong in 2009.Planting energy crops plays important roles in the development of new energy sources,reduction of greenhouse gas emission and environmental protection.[Conclusion] The study could provide theoretical foundations for the establishment of energy policy and study on development strategy of biomass energy in Shandong Province. | ZHENG Yan-lin1,2,LI Fu-li3,LIU Fang4 1.College of Science,Shandong University of Science and Technology,Qingdao 266510,China 2.College of Environmental Science and Engineering,Ocean University of China,Qingdao 266101,China 3.Qingdao Institute of Bioenergy and Bioprocess Technology,Chinese Academy of Sciences,Qingdao 266101,China 4.Animal Husbandry and Veterinary Bureau of Wenshang County,Jining 272500,China | 2011 | Meteorological and Environmental Research2011，2，7： | 6 |
| 3 | Molecular diversity of arbuscular mycorrhizal fungi at a large-scale antimony mining area in southern China显示文摘Arbuscular mycorrhizal fungi(AMF) have great potential for assisting heavy metal hyperaccumulators in the remediation of contaminated soils. However, little information is available about the community composition of AMF under natural conditions in soils contaminated by antimony(Sb). The objective of this study was to investigate the characteristics of AMF molecular diversity, and to explore the effects of Sb content and soil properties on the AMF community structure in an Sb mining area. Four Sb mine spoils and one adjacent reference area were selected from around the Xikuangshan mine in southern China. The association of AMF molecular diversity and community composition with the rhizosphere soils of the dominant plant species was studied by Polymerase Chain Reaction-Denaturing Gradient Gel Electrophoresis(PCR-DGGE). Results from all five studied sites showed that the diversity of AMF decreased with increasing Sb concentration. Principal component analysis(PCA) indicated that the AMF community structure was markedly different among these groups. Further redundancy analysis(RDA) showed that Sb contamination was the dominating factor influencing the AMF community structure in the Sb mine area. However, the multivariate analysis showed that, apart from the soil Sb content, extractable nitrogen content and organic matter content also attributed to AMF sequence distribution type. Some AMF sequences were only found in the highly contaminated area and these might be ideal candidates for improving phytoremediation efficiency in Sb mining regions. Gene sequencing analysis revealed that most species were affiliated with Glomus, suggesting that Glomus was the dominant AMF genus in the studied Sb mining area. | Yuan Wei Zhipeng Chen Fengchang Wu Hong Hou Jining Li Yuxian Shangguan Juan Zhang Fasheng Li Qingru Zeng | 2015 | Journal of Environmental Sciences2015，27，3： | 6 |
| 4 | Sustainability of urban drainage management: a perspective on infrastructure resilience and thresholds显示文摘 | Xiong NING Yi LIU Jining CHEN Xin DONG Wangfeng LI Bin LIANG | 2013 | Frontiers of Environmental Science & Engineering2013，7，5： | 4 |
| 5 | The effects of oleanolic acid on atherosclerosis in different animal models显示文摘 | Hanqiong Luo Jine Liu Qiong Ouyang Chunxiao Xuan Lanlan Wang Tingting Li Jun Liu | 2017 | Acta Biochimica et Biophysica Sinica2017，49，4： | 4 |
| 6 | Circular dichroism-like response of terahertz wave caused by phase manipulation via all-silicon metasurface显示文摘Chiral metasurfaces based on asymmetric meta-atoms have achieved artificial circular dichroism(CD),spin-dependent wavefront control,near-field imaging,and other spin-related electromagnetic control.In this paper,we propose and experimentally verify a scheme for achieving high-efficiency chiral response similar to CD of terahertz(THz)wave via phase manipulation.By introducing the geometric phase and dynamic phase in an all-silicon metasurface,the spin-decoupled terahertz transmission is obtained.The giant circular dichroism-like effect in the transmission spectrum is observed by using a random phase distribution for one of the circular polarization components.More importantly,the effect can be adjusted when we change the area of the metasurface illuminated by an incident terahertz beam.In addition,we also demonstrate the spin-dependent arbitrary wavefront control of the transmitted terahertz wave,in which one of the circularly polarized components is scattered,while the other forms a focused vortex beam.Simulated and experimental results show that this method provides a new idea for spin selective control of THz waves. | Jie Li Chenglong Zheng Guocui Wang Jitao Li Hongliang Zhao Yue Yang Zhang Zhang Maosheng Yang Liang Wu Jining Li Yating Zhang Yan Zhang Jianquan Yao | 2021 | Photonics Research2021，9，4： | 3 |
| 7 | EXISTENCE OF MULTIPLE POSITIVE SOLUTIONS TO SINGULAR SECOND ORDER NEUMANN BOUNDARY VALUE PROBLEMS显示文摘Using the fixed point index in cones, we study the existence of one and two positive solutions to singular second order Neumann boundary value problems under some conditions, which concerns the first eigenvalue of the relevant linear problem. Our results improve and extend some known ones in the previous literature. | Xiangping Chen, Rengui Li (Dept. of Math., Jining University, Qufu 273155, Shandong) | 2010 | Annals of Differential Equations2010，26，2： | 3 |
| 8 | Mining of a streptothricin gene cluster from Streptomyces sp.TP-A0356 genome via heterologous expression显示文摘Streptothricins (STs) are used commercially to treat bacterial and fungal diseases in agriculture. Mining of the sequenced microbial genomes uncovered two cryptic ST clusters from Streptomyces sp. C and Streptomyces sp. TP-A0356. The ST cluster from S. sp. TP-A0356 was verified by successful heterologous expression in Streptomyces coelicolor M145. Two new ST analogs were produced together with streptothricin F and streptothricin D in the heterologous host. The ST cluster was further confirmed by inactivation of gene stnO, which was proposed encoding an aminomutase supplying -lysines for the poly-β-Lys chain formation. A putative biosynthetic pathway for STs is proposed based on bioinformatics analyses of the ST genes and experimental evidence. | LI JinE GUO ZhengYan HUANG Wei MENG XiangXi AI GuoMin TANG GongLi CHEN YiHua | 2013 | Science China(Life Sciences)2013，56，7： | 3 |
| 9 | Predicting future dynamics from short-term time series using an Anticipated Learning Machine显示文摘Predicting time series has significant practical applications over different disciplines.Here,we propose an Anticipated Learning Machine(ALM)to achieve precise future-state predictions based on short-term but high-dimensional data.From non-linear dynamical systems theory,we show that ALM can transform recent correlation/spatial information of high-dimensional variables into future dynamical/temporal information of any target variable,thereby overcoming the small-sample problem and achieving multistep-ahead predictions.Since the training samples generated from high-dimensional data also include information of the unknown future values of the target variable,it is called anticipated learning.Extensive experiments on real-world data demonstrate significantly superior performances of ALM over all of the existing 12 methods.In contrast to traditional statistics-based machine learning,ALM is based on non-linear dynamics,thus opening a new way for dynamics-based machine learning. | Chuan Chen Rui Li Lin Shu Zhiyu He Jining Wang Chengming Zhang Huanfei Ma Kazuyuki Aihara Luonan Chen | 2020 | National Science Review2020，7，6： | 3 |
| 10 | The multi-soliton solutions of the CH-γ equation显示文摘This paper solves the integrable CH-γequation for analytical multiple soliton solutions with the Darboux transformation method.Some properties of the soliton solutions are different from the CH equation. | CHEN ChunLi~(1+) LI YiShen~2 ZHANG JinE~3 1 Department of Mathematics,Shanghai Jiaotong University,Shanghai 200240,China 2 Department of Mathematics,University of Science and Technology of China,Hefei 230026,China 3 SB and SEF,University of Hong Kong,Pokfulam Road,Hong Kong,China | 2008 | Science China Mathematics2008，51，2： | 3 |
| 11 | Identifying EGFR-Expressed Cells and Detecting EGFR Multi-Mutations at Single-Cell Level by Microfluidic Chip显示文摘EGFR mutations companion diagnostics have been proved to be crucial for the efficacy of tyrosine kinase inhibitor targeted cancer therapies. To uncover multiple mutations occurred in minority of EGFR-mutated cells,which may be covered by the noises from majority of unmutated cells, is currently becoming an urgent clinical requirement. Here we present the validation of a microfluidic-chip-based method for detecting EGFR multimutations at single-cell level. By trapping and immunofluorescently imaging single cells in specifically designed silicon microwells, the EGFR-expressed cellswere easily identified. By in situ lysing single cells, the cell lysates of EGFR-expressed cells were retrieved without cross-contamination. Benefited from excluding the noise from cells without EGFR expression, the simple and cost-effective Sanger's sequencing, but not the expensive deep sequencing of the whole cell population, was used to discover multi-mutations. We verified the new method with precisely discovering three most important EGFR drugrelated mutations from a sample in which EGFR-mutated cells only account for a small percentage of whole cell population. The microfluidic chip is capable of discovering not only the existence of specific EGFR multi-mutations,but also other valuable single-cell-level information: on which specific cells the mutations occurred, or whether different mutations coexist on the same cells. This microfluidic chip constitutes a promising method to promote simple and cost-effective Sanger's sequencing to be a routine test before performing targeted cancer therapy. | Ren Li Mingxing Zhou Jine Li Zihua Wang Weikai Zhang Chunyan Yue Yan Ma Hailin Peng Zewen Wei Zhiyuan Hu | 2018 | Nano-Micro Letters2018，10，1： | 2 |
| 12 | Development and analysis of a novel AF11-2 aptamer capable of enhancing the fluorescence of aflatoxin B1显示文摘Aflatoxin B1(AFB1)is one of the most common mycotoxins that threatens human health.As singlestranded oligonucleotides with high affinity and specificity,aptamers have incomparable effect on the targeted detection of AFB1.Herein,after 11 rounds of selection and analysis using a modified affinity chromatography-based SELEX strategy,the truncated 37 nt aptamer AF11-2 was successfully obtained.The aptamer shows good detection performance for AFB1,and can sensitively detect AFB1 in the range of 100-1000 nmol/L,with a detection limit of 42 nmol/L.In the detection of pretreated edible peanut oil samples,AF11-2 aptamer also showed a high recovery rate and good stability for AFB1,and achieved satisfactory results.In addition,AF11-2 aptamer can significantly enhance the fluorescence ability of AFB1,which is not available in traditional Afla17-2-3 aptamer.After molecular docking analysis,it was found that AF11-2 and Afla17-2-3 had different nucleotide binding sites for AFB1.Afla17-2-3 binds to the carbonyl O of AFB1,while AF11-2 binds to the pyrrolic O of AFB1,which may be the main reason that AF11-2 can enhance the fluorescence of AFB1. | Wenjing Li Yian Pei Jine Wang | 2022 | Chinese Chemical Letters2022，33，8： | 2 |
| 13 | Corrosion Resistance of Plasma Sprayed Ceramic Composite Coatings on Q235 Substrate显示文摘The corrosion resistance of SiO2/A12O3, TiO2/Al2O3 and (SiO2+TiO2)/Al2O3 ceramic composite coatings on Q235 substrate fabricated by means of plasma spraying was investigated. The results show that A12O3+13 wt pct TiO2 ceramic coating has the highest density, the lowest connected porosity and the best corrosion resistance. The corrosion mechanism of Q235 with ceramic coating has also been studied. | Dianran YAN Jining HE and XiangZhi LI School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300130, China Yangai LIU Yu ZHOU and Dechang JIA School of Materials Science and Engineering, Harbin institute of Technology, Harb | 2001 | Journal of Materials Science & Technology2001，17，1： | 1 |
| 14 | Analysis of sequence variations in 59 microRNAs in hepatocellular carcinomas显示文摘 | Jine Yang Fan Zhou Teng Xu Hua Deng Yi-Yuan Ge Changqing Zhang Jinqing Li Shi-Mei Zhuang | 2007 | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis2007，，： | 1 |
| 15 | Effect of hydrogen on microstructure and high tem- perature deformation of (TiB + TiC )/Ti-6A1-4V composite 显示文摘 | Lu Junqiang Qin Jining Lu Weijie Zhang Di Hou Hongliang Li Zhiqiang | 2009 | Materials Science and Engineering A2009，500，： | 1 |
| 16 | One-Pot Synthesis of Uniform Cu2O and CuS Hollow Spheres and Their Optical Limiting Properties显示文摘 | Gao Jining Li Quanshui Zhao Huabo | 2008 | Chemistry of Materials2008，20，19： | 1 |
| 17 | Gastroprotecrive activity of the unripe fruit extract of Juglans mandshurica in rats显示文摘 | Lee Eunbang Hyun Jinee Li Dawei | 2001 | Natural Product Sciences2001，7，3： | 1 |
| 18 | HvWRKY2 acts as an immunity suppressor and targets HvCEBiP to regulate powdery mildew resistance in barley显示文摘Plants use a sophisticated immune system to perceive pathogen infection and activate immune responses in a tightly controlled manner.In barley,Hv WRKY2 acts as a repressor in barley disease resistance to the powdery mildew fungus,Blumeria graminis f.sp.hordei(Bgh).However,the molecular features of Hv WRKY2 in its DNA-binding and repressor functions,as well as its target genes,are uncharacterized.We show that the W-box binding of Hv WRKY2 requires an intact WRKY domain and an upstream sequence of~75 amino acids,and the Hv WRKY2 W-box binding activity is linked to its repressor function in disease resistance.Chromatin immunoprecipitation(ChIP)-seq analysis identified HvCEBiP,a putative chitin receptor gene,as a target gene of Hv WRKY2 in overexpressing transgenic barley plants.ChIP-qPCR and Electrophoretic Mobility Shift Assay(EMSA)verified the direct binding of Hv WRKY2 to a W-boxcontaining sequence in the HvCEBiP promoter.Hv CEBiP positively regulates resistance against Bgh in barley.Our findings suggest that Hv WRKY2 represses barley basal immunity by directly targeting pathogen-associated molecular pattern(PAMP)recognition receptor genes,suggesting that Hv CEBiP and likely chitin signaling function in barley PAMP-triggered immune responses to Bgh infection. | Deshui Yu Renchun Fan Ling Zhang Pengya Xue Libing Liao Meizhen Hu Yanjun Cheng Jine Li Ting Qi Shaojuan Jing Qiuyun Wang Arvind Bhatt Qian-Hua Shen | 2023 | The Crop Journal2023，11，1： | 1 |
| 19 | Critical involvement of lysyl oxidase in seizure-induced neuronal damage through ERK-Alox5-dependent ferroptosis and its therapeutic implications显示文摘Recent insights collectively suggest the important roles of lysyl oxidase(LysOX)in the pathological processes of several acute and chronic neurological diseases,but the molecular regulatory mechanisms remain elusive.Herein,we explore the regulatory role of LysOX in the seizure-induced ferroptotic cell death of neurons.Mechanistically,LysOX promotes ferroptosis-associated lipid peroxidation in neurons via activating extracellular regulated protein kinase(ERK)-dependent 5-lipoxygenase(Alox5)signaling.In addition,overexpression of LysOX via adeno-associated viral vector(AAV)-based gene transfer enhances ferroptosis sensitivity and aggravates seizure-induced hippocampal damage.Our studies show that pharmacological inhibition of LysOX withβ-aminopropionitrile(BAPN)significantly blocks seizure-induced ferroptosis and thereby alleviates neuronal damage,while the BAPN-associated cardiotoxicity and neurotoxicity could further be reduced through encapsulation with bioresponsive amorphous calcium carbonate-based nanocarriers.These findings unveil a previously unrecognized LysOX-ERK-Alox5 pathway for ferroptosis regulation during seizure-induced neuronal damage.Suppressing this pathway may yield therapeutic implications for restoring seizure-induced neuronal injury. | Xiaoyuan Mao Xuan Wang Mingzhu Jin Qin Li Jining Jia Menghuan Li Honghao Zhou Zhaoqian Liu Weilin Jin Yanli Zhao Zhong Luo | 2022 | Acta Pharmaceutica Sinica B2022，12，9： | 1 |
| 20 | Molecular mechanism of mureidomycin biosynthesis activated by introduction of an exogenous regulatory gene ssa A into Streptomyces roseosporus显示文摘Mureidomycins(MRDs), a group of unique uridyl-peptide antibiotics, exhibit antibacterial activity against the highly refractory pathogen Pseudomonas aeruginosa. Our previous study showed that the cryptic MRD biosynthetic gene cluster(BGC) mrd in Streptomyces roseosporus NRRL 15998 could not be activated by its endogenous regulator 02995 but activated by an exogenous activator Ssa A from sansanmycin’s BGC ssa of Streptomyces sp. strain SS. Here we report the molecular mechanism for this inexplicable regulation. EMSAs and footprinting experiments revealed that Ssa A could directly bind to a 14-nt palindrome sequence of 5′-CTGRCNNNNGTCAG-3′ within six promoter regions of mrd. Disruption of three representative target genes(SSGG-02981, SSGG-02987 and SSGG-02994) showed that the target genes directly controlled by Ssa Awere essential for MRD production. The regulatory function was further investigated by replacing six regions of SSGG-02995 with those of ssa A.Surprisingly, only the replacement of 343–450 nt fragment encoding the 115–150 amino acids(AA) of Ssa A could activate MRD biosynthesis. Further bioinformatics analysis showed that the 115–150 AA situated between two conserved domains of Ssa A.Our findings significantly demonstrate that constitutive expression of a homologous exogenous regulatory gene is an effective strategy to awaken cryptic biosynthetic pathways in Streptomyces. | Ning Liu Hanye Guan Guoqing Niu Lingjuan Jiang Yue Li Jihui Zhang Jine Li Huarong Tan | 2021 | Science China(Life Sciences)2021，64，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员