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| 1 | Ligand-triggered de-repression of Arabidopsis heterotrimeric G proteins coupled to immune receptor kinases显示文摘 | Xiangxiu Liang Miaomiao Ma ,Zhaoyang Zhou Jinlong Wang Xinru Yang Shaofei Rao Guozhi Bi Lin Li Xiaojuan Zhang Jijie Chai She Chen Jian-Min Zhou | 2018 | Cell Research2018，28，5： | 13 |
| 2 | Effects of tourmaline on nitrogen removal performance and biofilm structures in the sequencing batch biofilm reactor显示文摘The effects of tourmaline on nitrogen removal performance and biofilm structures were comparatively investigated in two identical laboratory-scale sequencing batch biofilm reactors(SBBRs)(denoted SBBR1 and SBBR2) at different nitrogen loading rates(NLRs) varying from(0.24 ± 0.01) to(1.26 ± 0.02) g N/(L·day). SBBR1 was operated in parallel with SBBR2, but SBBR1 was filled with polyurethane foam loaded tourmaline(TPU) carriers and another(SBBR2) filled with polyurethane foam(PU) carriers. Results obtained from this study showed that the excellent and stable performance of SBBR1 was obtained. Ammonia nitrogen removal and total nitrogen removal were higher in SBBR1 than that in SBBR2 with increase of NLR. At an NLR of(0.24 ± 0.01) g N/(L·day), the majority of the spherical and elliptical bacteria were surrounded by the extracellular polymeric substance(EPS) and bacillus or filamentous bacteria in two SBBRs biofilms. When NLR increased to(1.26 ± 0.02) g N/(L·day), the clusters were more obvious in the SBBR1 biofilm than that in the SBBR2 biofilm. Bacteria in SBBR1 were inclined to synthesis more EPS, and the formed EPS could protect the bacteria from free ammonia(FA) under extreme condition NLR(1.26 ± 0.02) g N/(L·day). The results of polymerase chain reaction-denaturing gradient gel electrophoresis analysis showed that the microbial community similarity in SBBR2 decreased more obviously than that in SBBR1 with the increase of NLR, which the microbial community in SBBR1 was relatively stable. | Chong Tan Haoran Xu Di Cui Jinlong Zuo Junsheng Li Yubin Ji Shan Qiu Lin Yao Ying Chen Yingjie Liu | 2018 | Journal of Environmental Sciences2018，30，5： | 10 |
| 3 | Antihyperuricemic effect of mangiferin aglycon derivative J99745 by inhibiting xanthine oxidase activity and urate transporter 1 expression in mice显示文摘A mangiferin aglycon derivative J99745 has been identified as a potent xanthine oxidase(XOD) inhibitor by previous in vitro study. This study aimed to evaluate the hypouricemic effects of J99745 in experimental hyperuricemia mice, and explore the underlying mechanisms. Mice were orally administered 600 mg/kg xanthine once daily for 7 days and intraperitoneally injected 250 mg/kg oxonic acid on the 7 th day to induce hyperuricemia. Meanwhile, J99745(3, 10, and 30 mg/kg), allopurinol(20 mg/kg) or benzbromarone(20 mg/kg) were orally administered to mice for 7 days. On the 7 th day,uric acid and creatinine in serum and urine, blood urea nitrogen(BUN), malondialdehyde(MDA) content and XOD activities in serum and liver were determined. Morphological changes in kidney were observed using hematoxylin and eosin(H&E) staining. Hepatic XOD, renal urate transporter 1(URAT1), glucose transporter type 9(GLUT9), organic anion transporter 1(OAT1) and ATP-binding cassette transporter G2(ABCG2) were detected by Western blot and real time polymerase chain reaction(PCR). The results showed that J99745 at doses of 10 and 30 mg/kg significantly reduced serum urate, and enhanced fractional excretion of uric acid(FEUA). H&E staining confirmed that J99745 provided greater nephroprotective effects than allopurinol and benzbromarone. Moreover, serum and hepatic XOD activities and renal URAT1 expression declined in J99745-treated hyperuricemia mice. In consistence with the ability to inhibit XOD, J99745 lowered serum MDA content in hyperuricemia mice. Our resultssuggest that J99745 exerts urate-lowering effect by inhibiting XOD activity and URAT1 expression, thus representing a promising candidate as an anti-hyperuricemia agent. | Zhizhen Qin Shoubao Wang Yihuang Lin Ying Zhao Shengqian Yang Junke Song Tao Xie Jinlong Tian Song Wu Guanhua Du | 2018 | Acta Pharmaceutica Sinica B2018，8，2： | 9 |
| 4 | Bottom water temperature measurements in the South China Sea,eastern Indian Ocean and western Pacific Ocean显示文摘文章报道了一批新的海底底水温度(BWT)数据,其中南海(SCS)158个站位、东印度洋(EIO)30个站位及西太平洋(WPO)37个站位。基于这批新的BWT数据,获得南海和西太平洋海域底水温度与水深经验关系,可为地球物理和物理海洋提供准确、可靠的海底温度边界。这将有助于海底油气资源调查与评估。同时,这批实测数据表明:1)水深超过3500m的海域,其底水温度在南海约为2.47℃,比东印度洋(~1.34℃)和西太平洋(~1.60℃)稍微偏高。这与大洋传送带模式所预测的情况比较吻合。该模式认为:低温高盐的海水,从北大西洋格陵兰岛和冰岛附近海域下沉到深层,然后向南流动,再与南极洲周围海域的低温高盐海水一同向北进入印度洋和太平洋。而南海是一个相对比较封闭的热带边缘海,其内部海水与印度洋和菲律宾海交换有限,导致海水温度整体高于印度洋和太平洋。2)台西南盆地水深在2700~3000m的部分站位,其底水温高达约3.00℃,明显高于其周边同水深海域底水温度(平均值约为2.33℃)。这可能是台西南盆地海底水热活动导致的结果。3)在东印度洋和西太平洋水深超过4800m海域,底水温度随着水压增大稍有升高,其升高率分别为10.6mK·MPa^(-1)和12.0mK·MPa^(-1)。这与理论估算的深层底水绝热压力温度梯度范围较为吻合。这也意味着东印度洋和西太平洋深层底水,主要由绝热自压作用导致其温度随着深度的增大而升高。 | YANG Xiaoqiu SHI Xiaobin ZHAO Junfeng YU Chuanhai GAO Hongfang CHEN Aihua LU Yuanzheng CEN Xianrong LIN Weiren ZENG Xin XU Hehua REN Ziqiang ZHOU Shengqi XU Ziying SUN Jinlong KAMIYA Nana LIN Jian | 2018 | 热带海洋学报2018，37，5： | 8 |
| 5 | First light of the 1.8-m solar telescope–CLST显示文摘Large-aperture solar telescopes play an important role in solar observations and research,and require high temporal and spatial resolution[1].To solve some fundamental problems such as the solar dynamo,coronal heating,and the triggering of major solar eruptions,the spatial resolution for solar-atmosphere observation should reach at least 0.1 arcsec[2]. | ChangHui Rao NaiTing Gu XueJun Rao Cheng Li LanQiang Zhang JinLong Huang Lin Kong Ming Zhang YunTao Cheng Yi Pu Hua Bao YouMing Guo YangYi Liu JinSheng Yang LiBo Zhong ChangJun Wang Kai Fang XiaoJun Zhang DongHong Chen Cheng Wang XinLong Fan ZhiWu Yan KeLe Chen XiYa Wei Lei Zhu Hong Liu YongJian Wan Hao Xian WenLi Ma | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，10： | 6 |
| 6 | EAST-Educational Adaptive-optics Solar Telescope显示文摘For the public having a better understanding of solar activities,the Educational Adaptive-optics Solar Telescope(EAST)was built in July 2021 and is located at the Shanghai Astronomy Museum.The EAST consists of a 65 cm aperture solar telescope with a 177-element adaptive optics system and two-channel high resolution imaging system at the Hαand TiO bands,in addition to three full disk solar telescopes at CaK,Hαand TiO bands equipped on the tube of the main telescope.In this paper,the configuration of the EAST is described.Its performance and on-sky observational results are presented.The EAST,to our knowledge,is the most advanced solar telescope for the popularization of science in the world.Due to its excellent performance,the data acquired by the EAST can also be used for research on solar physics and space weather prediction. | Changhui Rao Xuejun Rao Zhimao Du Hua Bao Cheng Li Jinlong Huang Youming Guo Libo Zhong Qing Lin Xin Ge Jinsheng Yang Xinlong Fan Yangyi Liu Dan Jia Xin Li Mei Li Ming Zhang Yuntao Cheng Jiahui Zhou Jiawen Yao Lanqiang Zhang Naiting Gu | 2022 | Research in Astronomy and Astrophysics2022，22，6： | 3 |
| 7 | Application of a polycapillary x-ray optics in high pressure XAFS显示文摘 | Yude Li Xiaoyan Lin Shigang Liu Lirong Zheng Jinlong He Fei Guo Tianxi Sun | 2013 | Journal of Optics2013，，7： | 1 |
| 8 | Characteristics of the sea ice reflectance spectrum polluted by oil spills based on field experiments in the Bohai Sea显示文摘Oil spilled on the sea ice surface in the Bohai Sea of China is studied through the field measurements of the reflectance of a simulated sea ice-oil film mixed pixel. The reflection characteristics of sea ice and oil film are also analyzed. It is found that the mixed pixel of sea ice and oil film is a linear mixed pixel. The means of extracting sea ice pixels containing oil film is presented using a double-band ratio oil-film sea-ice index(DROSI) and a normalized difference oil-film sea-ice index(NDOSI) through the analysis of the reflectance curves of the sea iceoil film pixel for different ratios of oil film. The area proportion of the oil film in the sea ice-oil film pixel can be accurately estimated by the average reflectance of the band of 1 610–1 630 nm, and the volume of the spilled oil can be further estimated. The method of the sea ice-oil film pixel extraction and the models to estimate the proportion of oil film area in the sea ice-oil film pixel can be applied to the oil spill monitoring of the ice-covered area in the Bohai Sea using multispectral or hyperspectral remote sensing images in the shortwave infrared band(1 500–1 780 nm). | CHAO Jinlong LIU Chengyu LI Ying LIN Xia YAN Yu | 2017 | Acta Oceanologica Sinica2017，36，1： | 1 |
| 9 | Thrombopoietin induced proliferation and differentiation of fetal liver CD34^+ cells with phenotype change from hemopoiesis to neurogenesis显示文摘BACKGROUND: Previous studies have reported a neurotrophin-like motif in the N-terminal receptor binding region of the thrombopoietin (TPO) molecule, and have described localization of TPO and TPO receptor in the brain. Therefore, it is believed that TPO may be involved in regulation of neurogenesis. OBJECTIVE: To validate the effect of TPO on trans-differentiation, or differentiation from hematopoietic stem cells (HSCs) to neural stem cells (NSCs). DESIGN, TIME AND SETTING: Comparative studies were performed from March 2004 to April 2007 at the Department of Experimental Medicine, Northern Hospital, and the Department of Immunology, Fourth Military Medical University of Chinese PLA. MATERIALS: Human fetal liver (FL) was obtained from fetuses after water-balloon abortion. Gestational age ranged from 16 to 20 weeks. The study was approved by the Institutional Review Board and Ethics Committee of the Northern Hospital. TPO was kindly provided by Genentech Inc (USA). Iscove's Modified Dulbecco's Medium (IMDM) and neurobasalTM medium were purchased from Invitrogen (USA). MACS CD34 multisort kit was purchased from Miltenyi Biotec (Germany). METHODS: CD34+ cells were isolated from human FL mononuclear cells using MACS CD34 multisort kit and cultured at 1 × 105/mL in IMDM, containing TPO for 60 days with weekly changes of half of the medium. After culturing for 30 and 60 days, the TPO-induced cells were resuspended in neurobasalTM medium containing 10% fetal brain extracts and plated in an 8-well BIOCOAT poly-D-Lysine Culture Slide and cul- tured for another 7 days. MAIN OUTCOME MEASURES: Cell number, viability, phenotype and expression of hemopoiesis-related and neurogenesis-related proteins were examined by trypan blue exclusion with hemocytometer, immunoblot, immunocytochemistry and flow cytometry. RESULTS: After 60 days of induction with TPO, the cell number increased by 4.6-fold compared to the ini- tial culture. Although the proportion of the cells expressing the hemopoietic stem cell associated antigen (CD34) decreased steadily, both proportions of the cultured FL-derived CD34+ cells expressing CD41a and CD61 remained unchanged, which still accounted for 10%. Noticeably, the proportions of the cells express- ing nestin and epidermal growth factor receptor increased significantly (both > 50%), whereas the expression of more mature neural or glial proteins [microtubule-associated protein-2 (MAP2), glial fibrillary acidic pro- tein (GFAP), oligodendrocyte marker O4 (O4)] markers on the cultured fetal liver derived-CD34+ cells were at lower levels. After another 7 days incubation in neurobasal? medium, these TPO-induced cells formed neurospheres, which were labeled with nestin, and differentiated into cells with morphological characteristics of neurons, astrocytes and oligodendrocytes, which were labeled with MAP-2, GFAP, and O4, respectively. CONCLUSION: TPO can induce FL-derived HSCs to differentiate or trans-differentiate into NSCs and its progenitors. | Ning Ma Dongchu Ma Yi Tao Yinghui Sun Di Lin Huiying Yu Jinlong Jian Wei Jia Boquan Jin | 2008 | Neural Regeneration Research2008，3，4： | 1 |
| 10 | Ecological Carrying Capacity Prediction of Huainan City Based on GM–BP Neural Network显示文摘Evaluation of ecological carrying capacity is an important method of analyzing regional sustainable development, study on ecological carrying capacity is to settle the contradictions between resource and environment, and it is a significant basis for realizing regional sustainable development. This paper, on the basis of the academician Sun Tiehang's 'unification of three' for the eco-city construction, established ecological carrying capacity evaluation indexes for the traditional industrial and mining city—Huainan City; and applied GM–BP neural network coupling model for the dynamic evolution and prediction of ecological carrying capacity of Huainan City in the future decade. The results showed that ecological carrying capacity index of Huainan would be 2.13 by 2025, higher than the loadable state 1, so the ecological carrying capacity would keep in the over-loaded level, but the over-loaded degree would be lower than the current. Carrying capacity of arable land, energy and water resources contribute greatly to the improvement of ecological carrying capacity, thus it is imperative to adjust this unreasonable and unsustainable ecological consumption relationship, enhance environmental protection awareness and high-efficiency utilization of resources, and take an energy-saving and intensive development path. | LI Jiulin GU Kangkang CHU Jinlong JIANG Benchuan ANG Lin | 2016 | Journal of Landscape Research2016，8，1： | 1 |
| 11 | Lonicera caerulea polyphenols inhibit fat absorption by regulating Nrf2-ARE pathway mediated epithelial barrier dysfunction and special microbiota显示文摘Scope:High-fat diet(HFD)induces imbalance in the small intestine environment,where fat digestion and absorption mainly take place.This study aimed to elucidate the mechanisms by which Lonicera caerulea polyphenols(LCP)might inhibit fat absorption,from the perspective of small intestine microbiota and epithelial barrier integrity.Methods and results:Male Sprague-Dawley rats were given HFD with or without co-administration of LCP for 8 weeks.The results showed that LCP supplementation significantly decreased the levels of serum triglycerides(TG),total cholesterol(TC),and low-density lipoprotein cholesterol(LDL-C),and increased the contents of fecal sterols,in HFD rats.LCP also inhibited the dysfunction of the small intestine epithelial barrier,via alleviating the oxidative stress activated by Nrf2-ARE pathway,and by modulating the expressions of pro-inflammatory factors such as tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),cyclooxygenase-2(COX-2),nuclear factor kappa-B p65(NF-κB p65)and inducible nitric oxide synthase(iNOS)in the small intestine.Additionally,LCP administration restored the balance in small intestine microbiota and increased the abundance of the specific bacteria,such as Lactobacillus,involved in fat absorption.Conclusion:Our results demonstrated that LCP may be beneficial to inhibit fat absorption.The mechanism seems to be associated with the protection of the epithelial barrier integrity and the modulation of specific bacteria in the small intestine. | Yuehua Wang Ningxuan Gao Andrea Nieto-Veloza Lingxi Zhou Xiyun Sun Xu Si Jinlong Tian Yang Lin Xinyao Jiao Bin Li | 2023 | Food Science and Human Wellness2023，12，4： | 1 |
| 12 | The study of combustion synthesis of fine-particle γ-lithium aluminate显示文摘 | Wei Lin Xinde Bai Yunhan Ling Jinlong Yang Wenjun Ma | 2003 | Journal of Materials Science2003，，18： | 1 |
| 13 | Identification of let-7a-2-3p or/and miR-188-5p as prognostic biomarkers in cytogenetically normal acute myeloid leukemia显示文摘 | Jinlong S Lin F Yonghui L | 2015 | PLo S One2015，10，01： | 1 |
| 14 | Projected land use changes in the Qinghai-Tibet Plateau at the carbon peak and carbon neutrality targets显示文摘Based on historical land use for eight periods from 1980 to 2020 and the projected land use under seven Shared Socioeconomic Pathways(SSPs:SSP1-1.9,SSP1-2.6,SSP2-4.5,SSP3-7.0,SSP4-3.4,SSP4-6.0,and SSP5-8.5)from 2021 to 2100,we conducted a study on past and future land use changes in the Qinghai-Tibet Plateau(QTP).This work aims to reveal the land use changes during the carbon peak(2021-2040)and carbon neutrality(2051-2070)periods and at the end of the 21st century(2081-2100).The results show that:(1)in the historical period(1980-2020),the land use types in the QTP were grassland(1475×10^(3)km^(2),58.2%),barren land(685×10^(3)km^(2),27.0%),forest land(243×10^(3)km^(2),9.6%),water(114×10^(3)km^(2),4.5%),cropland(18.6×10^(3)km^(2),0.7%)and urban land(0.3×10^(3)km^(2),0.01%).(2)Relative to the baseline period(1995-2014),the area of grassland is projected to decrease by 0.7%(SSP4-6.0)-5.4%(SSP2-4.5)(0.5-3.9%of the total area of the QTP),2.8%(SSP4-6.0)-12.5%(SSP3-7.0)(2.1-9.4%of the total area of the QTP)and 6.1%(SSP4-6.0)-21.7%(SSP4-3.4)(4.6-16.4%of the total area of the QTP)in the future three periods.In contrast,the forest land area is projected to increase,by approximately 2.5%(SSP4-6.0)to 30.1%(SSP3-7.0)(0.3-4.3%of the total area of the QTP),9.2%(SSP4-6.0)to 56.5%(SSP2-4.5)(1.3-8.0%of the total area of the QTP),and 21.2%(SSP4-6.0)to 72.8%(SSP2-4.5)(3.0-10.2%of the total area of the QTP)in the future three periods,respectively.(3)Approximately 0.4(SSP4-6.0)to 6.9%(SSP5-8.5),0.9(SSP4-6.0)to 2.7%(SSP4-3.4),and 0.04(SSP5-8.5)to 3.5%(SSP1-1.9)of land is expected to convert from grassland to forest land in the future three periods,respectively.The shift from grassland to forest land area is likely to enhance the carbon sink potential of the QTP in the future period. | Runhong XU Peijun SHI Miaoni GAO Yanjun WANG Guojie WANG Buda SU Jinlong HUANG Qigen LIN Tong JIANG | 2023 | Science China Earth Sciences2023，66，6： | 0 |
| 15 | Elucidating the suppression of lithium dendrite growth with a void-reduced anti-perovskite solid-state electrolyte pellet for stable lithium metal anodes显示文摘Solid-state lithium-metal batteries,with their high theoretical energy density and safety,are highly promising as a next-generation battery contender.Among the alternatives proposed as solid-state electrolyte,lithium-rich anti-perovskite(Li RAP)materials have drawn the most interest because of high theoretical Li^(+)conductivity,low cost and easy processing.Although solid-state electrolytes are believed to have the potential to physically inhibit the lithium dendrite growth,lithium-metal batteries still suffer from the lithium dendrite growth and thereafter the short circuiting.The voids in practical Li RAP pellets are considered as the root cause.Herein,we show that reducing the voids can effectively suppress the lithium dendrite growth.The voids in the pellet resulted in an irregular Li^(+)flux distribution and a poor interfacial contact with lithium metal anode;and hence the ununiform lithium dendrites.Consequently,the lithium-metal symmetric cell with void-reduced Li_(2)OHCl-HT pellet was able to display excellent cycling performance(750 h at 0.4 m A cm^(-2))and stability at high current density(0.8 m A cm^(-2)for 120 h).This study provides not only experimental evidence for the impact of the voids in Li RAP pellets on the lithium dendrite growth,but also a rational pellet fabrication approach to suppress the lithium dendrite growth. | Yu YeXinyan Ye Haoxian Zhu Juncao Bian Haibin Lin Jinlong Zhu Yusheng Zhao | 2023 | Journal of Energy Chemistry2023，，2： | 0 |
| 16 | Changes in Sleep Duration and the Risk of Cognitive Impairment Among Older Adults Aged 65 Years and Over—China,2014–2019显示文摘Summary What is already known about this topic?Earlier studies indicated that shorter or excessive sleep duration at baseline was related to cognitive impairment.Yet few studies have been concerned with the association between sleep duration changes and cognitive performance,especially in low-and middleincome countries.What is added by this report?A prospective cohort study suggests that maintaining moderate sleep duration may lead to optimal cognitive performance.Either decreasing,increasing,or keeping a longer sleep duration is associated with the risk of cognitive impairment among Chinese elderly aged 65 years and over. | Yue Wei Heming Pei Jinlong Lin Xiaojin Yan Gong Chen | 2022 | China CDC weekly2022，4，42： | 0 |
| 17 | Wide-pH-range adaptable ammonia electrosynthesis from nitrate on Cu-Pd interfaces显示文摘Ammonia production via electrochemical nitrate reduction is essential for environmental protection and the emerging hydrogen economy. Complex nitrate wastewater with a wide pH range calls for flexible catalysts with high selectivity. A high Faradaic efficiency(FE) of NH3 cannot be obtained under strong acid or alkaline conditions due to the uncontrollable adsorption energy and coverage of hydrogen species(H*) on active sites. This article describes the design and fabrication of a copper-palladium(Cu-Pd) alloy nanocrystal catalyst that inhibits H2 and nitrite generation in electrolytes with different nitrate concentrations and varied pH. The interfacial sites of Cu-Pd alloys could enhance the adsorption energy and coverage of H* while increasing the reaction rate constant of NO_(2)*-to-NO*, which achieves a rapid conversion of NO_(2)* along with a decreased FE of NO_(2)-. Under ambient conditions, optimal FE(NH3) is close to 100% at a wide pH range, with the solar-to-chemical conversion efficiency approaching 4.29%. The combination of thermodynamics and kinetics investigations would offer new insights into the reduction mechanism of NO_(2)* for further development of nitrate reduction. | Yongtao Wang Peng Zhang Xiaoyun Lin Gong Zhang Hui Gao Qingzhen Wang Zhi-Jian Zhao Tuo Wang Jinlong Gong | 2023 | Science China Chemistry2023，66，3： | 0 |
| 18 | AKG/OXGR1 promotes skeletal muscle blood flow and metabolism by relaxing vascular smooth muscle显示文摘In response to contraction during exercise,skeletal muscle growth and metabolism are dynamically regulated by nerve action,blood flow,and metabolic feedback.α-Ketoglutarate(AKG),a bioactive intermediate in the tricarboxylic acid cycle released during exercise,has been shown to promote skeletal muscle hypertrophy.However,the underlying mechanism of AKG in regulating skeletal muscle development and metabolism is still less known.2-Oxoglutarate receptor 1(OXGR1),the endogenous AKG receptor,is found to be distributed in the vascular smooth muscle(VSM)of skeletal muscles.OXGR1 knockout results in skeletal muscle atrophy,accompanied by decreased expression of myosin heavy chain I(MyHC I),capillary density,and endurance exercise capacity.Furthermore,the study found that dietary AKG supplementation increased mice endurance exercise distance,MyHC I/MyHC IIb ratio,arteriole,and capillary densities in skeletal muscle.Meanwhile,acute AKG administration gradually increased the blood flow in the lower limbs.Further,by using OXGR1 global knockout and OXGR1 VSM-specific(MYH11-Cre×OXGR1-FloxP)knockdown models,we found that OXGR1 in VSM is essential for AKG-induced improvement of skeletal muscle performances.According to the in vitro study,AKG expanded the cell area in VSM with a decreased intracellular pH by OXGR1.Our results demonstrated a novel role of AKG/OXGR1 in VSM of skeletal muscle to regulate blood flow and then enhance slow muscle fiber conversion and capillarization.These findings provide a theoretical basis for the AKG/OXGR1 signaling pathway to maintain human muscle function and improve meat production and livestock and poultry meat quality. | Jinping Yang Guli Xu Yiming Xu Pei Luo Yexian Yuan Lin Yao Jingjing Zhou Yunlong Zhu Ishwari Gyawali Chang Xu Jinlong Feng Zewei Ma Yuxian Zeng Songbo Wang Ping Gao Canjun Zhu Qingyan Jiang Gang Shu | 2022 | Life Metabolism2022，1，3： | 0 |
| 19 | GIS-based Ecological Control Line Planning of Landscape City显示文摘Against the background of accelerated urbanization in China, the expansion of urban land uses, especially the construction of development zones have incorporated urban development land uses, and more ecological spaces have been invaded by construction activities. However, the maintenance of urban ecological security, scientificity, integrality and continuity of ecosystem, as well as scientificity of the defining methods and the effective supervision of the basic ecological control line have become bones of contention. This paper, from the perspective of 'anti-planning', synthesized the theories and methods such as urban-rural planning, ecology and GIS, coupled ecological sensitivity assessment and ecological security pattern to define the basic ecological control lines of the planning area in Anqing City. The basic ecological control line area includes ecological baseline area and ecological development area. Management and control strategies of basic ecological control line were elaborated from the following aspects: implementation of the basic ecological control line, protection and utilization of ecological resources within the lines, solutions to existing construction land within the lines, adjustment mechanism and implementation guarantee mechanism of basic ecological control line. | WANG Yongzheng ANG Lin TANG Houming CHU Jinlong GU Kangkang | 2016 | Journal of Landscape Research2016，8，1： | 0 |
| 20 | Fluorine Effects for Tunable C-C and C-S Bond Cleavage in Fluoro-Julia-Kocienski Intermediates显示文摘Classical Julia-Kocienski fluoroolefination represents an indispensable platform for the construction of monofluoroalkenes.Nevertheless,its complex multistep mechanistic manifold along with the unrevealed intrinsic“fluorine effect”in nucleophilic reactions might be responsible for the difficult control of the original stereoselectivity and is thus often ambiguous to predict.Herein,a novel strategy involving the defined fluorine effect and new reaction mechanism was developed for tunable C-C and C-S bond cleavage,providing a versatile avenue for highly stereoselective and easily scalable construction of diverse monofluoroalkenes.Density functional theory(DFT)investigations indicate the fluorine substituents can activate the C-C and C-S bond leading toα-elimination by antiphase orbital interaction.The rate-limiting step were calculated via fourmembered transition states with ring strain.Both the sterically eclipsed repulsion and secondary orbital interaction affect the stereoselectivity. | Lei Kang Yongjia Lin Zeng Gao Jinlong Zhang Huameng Yang Jinlong Qian Qian Peng Gaoxi Jiang | 2021 | CCS Chemistry2021，3，6： | 0 |
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