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| 1 | A journey to understand wheat Fusarium head blight resistance in the Chinese wheat landrace Wangshuibai显示文摘Fusarium head blight(FHB) or scab caused by Fusarium graminearum is a major threat to wheat production in China as well as in the world. To combat this disease, multiple efforts have been carried out internationally. In this article, we review our long-time effort in identifying the resistance genes and dissecting the resistance mechanisms by both forward and reverse genetics approaches in the last two decades. We present recent progress in resistance QTL identification, candidate functional gene discovery, marker-assisted improvement of FHB resistant varieties, and findings in investigating association of signal molecules, such as Ca^(++),SA, JA, and ET, with FHB response, with the assistance from rapidly growing genomics platforms. The information will be helpful for designing novel and efficient approaches to curb FHB. | Haiyan Jia Jiyang Zhou Shulin Xue Guoqiang Li Haisheng Yan Congfu Ran Yiduo Zhang Jinxing Shi Li Jia Xin Wang Jing Luo Zhengqiang Ma | 2018 | The Crop Journal2018，6，1： | 24 |
| 2 | Terrestrial heat flow in Junggar Basin, Northwest China显示文摘Based on temperature logs of 117 boreholes and thermal conductivity of 119 rock samples, the first group of 35 heat flow data in the Junggar Basin are presented. The thermal gradients vary between 11.6 and 26.5℃/km , and the thermal conductivity changes from 0.17 to 3.6 W/mK. Heat flow ranges from 23.4 to 53.7 mW/m2 with a mean of (42.3±7.7) mW/m2. The heat flow pattern shows that heat flow is higher in the uplifts and lower in the depressions. The factors affecting the heat flow and its distribution include basin type, basement structure, sediment thickness, radioactive heat generation, etc. The overall low present-day heat flow in the Junggar Basin reflected its tectonothermal evolution characterized by lithospheric thickening, thrust and fault at shallow crust as well as consequently quick subsidence during the Late Cenozoic. | WANG Shejiao HU Shengbiao LI Tiejun WANG Jiyang ZHAO Wenzhi | 2000 | Chinese Science Bulletin2000，45，19： | 10 |
| 3 | Geothermal measurements in the pilot-boreholes of the China Continental Scientific Drilling显示文摘The geothermal measurements in the pilot-boreholes of the China Continental Scientific Drilling (CCSD) indicate that the temperature gradients in the target area of the deep drilling range from 19 to 26℃/km, which is lower than that (25-30℃/km) for the global continental area and similar to that for the KTB (21-28℃/km). Thermal conductivity measurements for 44 core samples show that the ultra-high pressure (UHP) metamorphic rocks have 50% higher thermal conductivity (with a mean of 3.94±1.26 W/mK) than that for the average value of the upper crust. The measured heat flow values vary between 76 and 80 mW/m2, higher than that for the global continental area (65±1.6 mW/m2) and the continental China (61±15.5mW/m2) as well as the adjacent North Jiangsu Basin (68 mW/m2), butlower than that below 1000 m in the KTB (85 mW/m2). The elevated heat flow in the pilot-boreholes can be attributed to the lateral heat concentration due to higher rock thermal conductivity of the VHP belt than that of the adjacent | WANG Jiyang HU Shengbiao YANG Wencai CHEN Benhe CHEN Zhenyan LI Tiejun | 2001 | Chinese Science Bulletin2001，46，20： | 7 |
| 4 | Radiation-pressure-driven mechanical oscillations in silica microdisk resonators on chip显示文摘We demonstrate radiation-pressure-driven mechanical oscillations from high optical quality factor silica microdisk resonators on chip. Mechanical quality factors of 3520 in air and 12540 in vacuum for the fundamental radial breathing modes are obtained from 73 μm-diameter silica microdisks with mechanical frequencies of ~51 MHz. The measured mechanical oscillation threshold powers for the input light are determined to be 62.5 μW in air and down to 26.6 μW in vacuum. | WANG GuanZhong ZHAO MingMing MA JiYang LI GuanYu CHEN Yuan JIANG XiaoShun XIAO Min | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，5： | 6 |
| 5 | Plasma biomarker screening for liver fibrosis with the N-terminal isotope tagging strategy显示文摘A non-invasive diagnostic approach is crucial for the evaluation of severity of liver disease,treatment decisions,and assessing drug efficacy.This study evaluated plasma proteomic profiling via an N-terminal isotope tagging strategy coupled with liquid chromatography/Fourier transform ion cyclotron resonance mass spectrometry measurement to detect liver fibrosis staging.Pooled plasma from different liver fibrosis stages,which were assessed in advance by the current gold-standard of liver biopsy,was quantitatively analyzed.A total of 72 plasma proteins were found to be dysregulated during the fibrogenesis process,and this finding constituted a valuable candidate plasma biomarker bank for follow-up analysis.Validation results of fibronectin by Western blotting reconfirmed the mass-based data.Ingenuity Pathways Analysis showed four types of metabolic networks for the functional effect of liver fibrosis disease in chronic hepatitis B patients.Consequently,quantitative proteomics via the N-terminal acetyl isotope labeling technique provides an effective and useful tool for screening plasma candidate biomarkers for liver fibrosis.We quantitatively monitored the fibrogenesis process in CHB patients.We discovered many new valuable candidate biomarkers for the diagnosis of liver fibrosis and also partly identified the mechanism involved in liver fibrosis disease.These results provide a clearer understanding of liver fibrosis pathophysiology and will also hopefully lead to improvement of clinical diagnosis and treatment. | LI ShuLong LIU Xin WEI Lai WANG HuiFen ZHANG JiYang WEI HanDong QIAN XiaoHong JIANG Ying HE FuChu | 2011 | Science China(Life Sciences)2011，54，5： | 6 |
| 6 | Visible Kerr comb generation in a high-Q silica microdisk resonator with a large wedge angle显示文摘This paper describes the specially designed geometry of a dry-etched large-wedge-angle silica microdisk resonator that enables anomalous dispersion in the 780 nm wavelength regime. This anomalous dispersion occurs naturally without the use of a mode-hybridization technique to control the geometrical dispersion. By fabricating a1-μm-thick silica microdisk with a wedge angle as large as 56° and an optical Q-factor larger than 107, we achieve a visible Kerr comb that covers the wavelength interval of 700–897 nm. The wide optical frequency range and the closeness to the clock transition at 698 nm of 87 Sr atoms make our visible comb a potentially useful tool in optical atomic clock applications. | Jiyang Ma Longfu Xiao Jiaxin Gu Hao Li Xinyu Cheng Guangqiang He Xiaoshun Jiang Min Xiao | 2019 | Photonics Research2019，7，5： | 5 |
| 7 | Effect of preoperative nutrition therapy type and duration on short-time outcomes in gastric cancer patient with gastric outlet obstruction显示文摘Objective:To avoid perioperative complications caused malnutrition,nutrition therapy is necessary in gastric outlet obstruction(GOO)patients.Compared to parenteral nutrition(PN),enteral nutrition(EN)is associated with many advantages.This study aimed to investigate whether preoperative EN has beneficial clinical effects compared to preoperative PN in gastric cancer patients with GOO undergoing surgery.Methods:According to the methods of preoperative nutrition therapy,143 patients were divided into EN group(n=42)and PN group(n=101)between January 2013 and December 2017 at the Chinese People’s Liberation Army General Hospital.Multiple logistic regression models were used to assess the association between the methods of preoperative nutrition therapy and postoperative day of flatus passage.The generalized additive model and twopiecewise linear regression model were used to calculate the inflection point of the preoperative nutritional therapy time on the postoperative day of flatus passage in the PN group.Results:EN shortened the postoperative day of flatus passage in gastric cancer patients with GOO,which is a protective factor,especially in patients who underwent non-radical operations and the postoperative day of flatus passage reduced when the preoperative PN therapy was up to 3 d and a longer PN therapy(>3 d)did not accelerate the postoperative recovery of gastrointestinal functions.Conclusions:Preoperative EN therapy would benefit gastric cancer patients with GOO by accelerating postoperative recovery.For patients with absolute obstruction,no more than 3-day PN therapy is recommended if patients can tolerate general anesthesia and surgery. | Jiyang Li Shaoqing Li Hongqing Xi Peifa Liu Wenquan Liang Yunhe Gao Chuang Wang Bo Wei Lin Chen Yun Tang Zhi Qiao | 2021 | Chinese Journal of Cancer Research2021，33，2： | 4 |
| 8 | Human apolipoprotein A-I exerts a prophylactic effect on high-fat diet-induced atherosclerosis via inflammation inhibition in a rabbit model显示文摘Apolipoprotein A-I (apoA -- 我) 是高密度的脂蛋白的主要功能的蛋白质部分。人的 apoA 的预防效果和机制 -- 我在动脉粥样硬化上(作为) 被调查在一高脂肪象兔子模型导致食谱。兔子与 apoA 被注射 -- 我每周一次当喂时为 20 个星期的高脂肪的饮食。我们的结果显示出那 apoA -- 我能提起高密度的脂蛋白胆固醇的浆液水平并且类脂化合物总数胆固醇, triglyceride,和低密度的脂蛋白胆固醇减少那些在作为兔子。减少的大动脉的匾区域和大动脉的损害度被染色的油红 O 也观察并且他在 apoA-I-treated 染色高脂肪象兔子导致食谱。进一步的学习阐明了那 apoA -- 我能包括细胞间的粘附分子的一些煽动性的调停人的表示打的下面调整 1,脉管的粘附 molecule-1 (VCAM-1 ) ,单核白血球 chemoattractant protein-1,肿瘤坏死因素 -- , interleukin-6 (IL-6 ) ,和在浆液和主动脉的 C 反应的蛋白质作为兔子。另外,即时量的 RT-PCR 分析证明 apoA --我注入减少了二个 支持inflammatory 分子的 mRNA 层次,即原子因素 kappa B ( NF-B )和 cyclooxygenase-2 ( COX-2 ),在主动脉作为兔子,它在 endothelial VCAM-1 和 IL-6 mRNA 抄写与伴随物减小被联系。一起,我们的结果支持 atheroprotective 和 apoA 的预防角色 -- 我可以与它的反煽动性的效果在 vivo,和这项活动被相关。 | Jiyang Li Weina Wang Lei Han Meiqing Feng Hui Lu Li Yang Xiangxiang Hu Si Shi Shanshan Jiang Qian Wang Li Ye | 2017 | Acta Biochimica et Biophysica Sinica2017，49，2： | 3 |
| 9 | High-Q silica microdisk optical resonators with large wedge angles on a silicon chip显示文摘We experimentally demonstrate high optical quality factor silica microdisk resonators on a silicon chip with large wedge angles by reactive ion etching. For 2-μm-thick microresonators, we have achieved wedge angles of 59°, 63°,70°, and 79° with optical quality factors of 2.4 × 10~7, 8.1 × 10~6, 5.9 × 10~6, and 7.4 × 10~6, respectively, from ~80 μm diameter microresonators in the 1550 nm wavelength band. Also, for 1-μm-thick microresonators, we have obtained an optical quality factor of 7.3 × 10~6 with a wedge angle of 74°. | Guanyu Li Pei Liu Xiaoshun Jiang Chao Yang Jiyang Ma Hongya Wu Min Xiao | 2015 | Photonics Research2015，3，5： | 2 |
| 10 | Metal-Organic Framework-based Wood Aerogel for Effective Removal of Micro/Nano Plastics显示文摘The large amount of microplastic pollution in the aquatic environment has been regarded as a major challenge facing the world. Although some traditional water treatment processes can effectively remove microplastics in the millimeter range, research is still needed to solve the problem of removing smaller microplastics. Here, we made a durable zinc metal-organic framework-based composite material ZIF-8@Aerogel by in situ growing ZIF-8 on wood aerogel fibers, which can successfully remove microplastics in simulated water and seawater. The removal efficiencies on micro/nano plastics including poly(1,1-difluoroethylene)(60-110 nm) and polystyrene(90-140 nm) reached 91.4% and 85.8%, respectively. This work is expected to provide a new and efficient way to remove small-sized microplastic particles in the environment. | YOU Dongyu ZHAO Yujuan YANG Weiting PAN Qinhe LI Jiyang | 2022 | Chemical Research in Chinese Universities2022，38，1： | 2 |
| 11 | Use of stem cell transplantation to treat epilepsy A Web of Science-based literature analysis显示文摘OBJECTIVE: To identify global research trends in the use of stem cell transplantation to treat epilepsy. DATA RETRIEVAL: We performed a bibliometric analysis of studies on the use of stem cell transplantation to treat epilepsy during 2002-2011, retrieved from Web of Science, using the key words epilepsy or epileptic or epilepticus or seizure and 'stem cell'. SELECTION CRITERIA: Inclusion criteria: (a) peer-reviewed published articles on the use of stem cell transplantation to treat epilepsy indexed in Web of Science; (b) original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items. MAIN OUTCOME MEASURES: (a) Annual publication output; (b) type of publication; (c) publication by research field; (d) publication by journal; (e) publication by author; (f) publication by country and institution; (g) publications by institution in China; (h) most-cited papers; and (i) papers published by Chinese authors or institutions. RESULTS: A total of 460 publications on the use of stem cell transplantation to treat epilepsy were retrieved from Web of Science, 2002-2011. The number of publications gradually increased over the 10-year study period. Articles and reviews constituted the major types of publications. More than half of the studies were in the field of neuroscience/neurology. The most prolific journals for this topic were Epilepsia, Bone Marrow Transplantation, and Journal of Neuroscience. Of the 460 publications, almost half came from American authors and institutions; relatively few papers were published by Chinese authors or institutions. CONCLUSION: Literature on stem cell transplantation for epilepsy includes many reports of basic research, but few of clinical trials or treatments. Exact effects are not yet evaluated. Epilepsy rehabilitation is a long-term, complex, and comprehensive system engineering. With advances in medical development, some effective medical, social and educational measures are needed to facilitate patient's treatment and training and accelerate the recovery of life ability, learning ability and social adaptability to the largest extent to improve patient's quality of life. | Zhongmin Yin Yushu Dong Jiyang Zhang Li Wang | 2012 | Neural Regeneration Research2012，7，33： | 2 |
| 12 | A Markov decision problem in a risk model with interest rate and Markovian environment显示文摘We consider the compound binomial model in a Markovian environment presented by Cossette et al.(2004). We modify the model via assuming that the company receives interest on the surplus and a positive real-valued premium per unit time, and introducing a control strategy of periodic dividend payments. A Markov decision problem arises and the control objective is to maximize the cumulative expected discounted dividends paid to the shareholders until ruin minus a discounted penalty for ruin. We show that under the absence of a ceiling of dividend rates the optimal strategy is a conditional band strategy given the current state of the environment process. Under the presence of a ceiling for dividend rates, the character of the optimal control strategy is given. In addition, we offer an algorithm for the optimal strategy and the optimal value function.Numerical results are provided to illustrate the algorithm and the impact of the penalty. | TAN JiYang YANG XiangQun LI ZiQiang CHENG YangJin | 2016 | Science China Mathematics2016，59，1： | 2 |
| 13 | Synthesis of Nd^3+ doped nan o-crystalline yttrium aluminum gamet (YAG) powders leading to transparent ceramic 显示文摘 | Li Xia Li Qiang Wang Jiyang l | 2007 | Optical Materials2007，29，5： | 1 |
| 14 | Rapid synthesis of YAG nano-sized powders by a novel method显示文摘 | Li Xia Liu Hong Wang Jiyang | 2004 | Mater Lett2004，58，19： | 1 |
| 15 | Clinical features and risk factors for post-partum depression in a large cohort of Chinese women with recurrent major depressive disorder显示文摘 | Tian Tian Yihan Li Dong Xie Yifeng Shen Jianer Ren Wenyuan Wu Chengbin Guan Zhen Zhang Danning Zhang Chengge Gao Xiaoming Zhang Jinbo Wu Hong Deng Gang Wang Yunshu Zhang Yun Shao Han Rong Zhaoyu Gan Yan Sun Bin Hu Jiyang Pan Yi Li Shufan Sun Libo Song Xue | 2011 | Journal of Affective Disorders2011，，3： | 1 |
| 16 | Anti-hepatitis B Virus Activities of Astragaloside IV Isolated from Radix Astragali显示文摘 | Wang Shuguang Li Jiyang | 2009 | Biological & Pharmaceutical Bulletin2009，32，1： | 1 |
| 17 | Solvothermal synthesis and luminescent properties of YAG : Tb nano-sized phosphors显示文摘 | Li Xia Liu Hong Wang Jiyang | 2005 | J Phys Chem Solids2005，66，1： | 1 |
| 18 | Preparation of YAG:Nd nano-sized powder by co-precipitation method显示文摘 | Li Xia Liu Hong Wang Jiyang | 2004 | Mater Sci Eng A2004，379，12： | 1 |
| 19 | Synthesis of Nd^3+ doped nano-crystalline yttrium aluminum garnet (YAG) powders leading to transparent ceramic显示文摘 | Li Xia Li Qiang Wang Jiyang | 2007 | Opt Mater2007，29，： | 1 |
| 20 | Groundwater maintains dune landscape 显示文摘 | CHEN Jiansheng LI Ling WANG Jiyang | 2004 | Nature2004，432，： | 1 |
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