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| 1 | Blood glucose changes surrounding initiation of tumor-necrosis factor inhibitors and conventional disease-modifying anti-rheumatic drugs in veterans with rheumatoid arthritis显示文摘AIM To determine the scope of acute hypoglycemic effects for certain anti-rheumatic medications in a large retrospective observational study. METHODS Patients enrolled in the Veterans Affairs Rheumatoid Arthritis (VARA) registry were selected who, during follow-up, initiated treatment with tumor necrosis factor inhibitors (TNFi's, including etanercept, adalimumab, infliximab, golimumab, or certolizumab), prednisone, or conventional disease-modifying anti-rheumatic drugs(DMARDs), and for whom proximate random blood glucose (RBG) measurements were available within a window 2-wk prior to, and 6 mo following, medication initiation. Similar data were obtained for patients with proximate values available for glycosylated hemoglobin A1C values within a window 2 mo preceding, and 12 mo following, medication initiation. RBG and A1C measurements were compared before and after initiation events using paired t-tests, and multivariate regression analysis was performed including established comorbidities and demographics.RESULTS Two thousands one hundred and eleven patients contributed at least one proximate measurement surrounding the initiation of any examined medication. A significant decrease in RBG was noted surrounding 653 individual hydroxychloroquine-initiation events(-3.68 mg/dL, P = 0.04), while an increase was noted for RBG surrounding 665 prednisone-initiation events(+5.85 mg/d L, P < 0.01). A statistically significant decrease in A1C was noted for sulfasalazine initiation, as measured by 49 individual initiation events(-0.70%, P < 0.01). Multivariate regression analyses, using methotrexate as the referent, suggest sulfasalazine (β =-0.58, P = 0.01) and hydroxychloroquine(β =-5.78, P = 0.01) use as predictors of lower post-medicationinitiation RBG and A1C values, respectively. Analysis by drug class suggested prednisone (or glucocorticoids) as predictive of higher medication-initiation event RBG among all start events as compared to DMARDs, while this analysis did not show any drug class-level effect for TNFi. A diagnosis of congestive heart failure(β = 4.69, P = 0.03) was predictive for higher post-initiation RBG values among all medication-initiation events.CONCLUSION No statistically significant hypoglycemic effects surrounding TNFi initiation were observed in this large cohort. Sulfasalazine and hydroxychloroquine may have epidemiologically significant acute hypoglycemic effects. | Patrick R Wood Evan Manning Joshua F Baker Bryant England Lisa Davis Grant W Cannon Ted R Mikuls Liron Caplan | 2018 | World Journal of Diabetes2018,9,2: | 8 |
| 2 | Rat Middle Cerebral Artery Occlusion: Evaluation of the Model and Development of a Neurologic Examination显示文摘 | JOSHUA B. BEDERSON LAWRENCE H. PITTS MILES TSUJI MERRY C. NISHIMURA RICHARD L. DAVIS HENRY BARTKOWSKI | 1986 | Stroke1986,,3: | 5 |
| 3 | What moves housing markets: A variance decomposition of the rent–price ratio显示文摘 | Sean D. Campbell Morris A. Davis Joshua Gallin Robert F. Martin | 2009 | Journal of Urban Economics2009,,2: | 3 |
| 4 | Rat Middle Cerebral Artery Occlusion: Evaluation of the Model and Development of a Neurologic Examination显示文摘 | JOSHUA B. BEDERSON LAWRENCE H. PITTS MILES TSUJI MERRY C. NISHIMURA RICHARD L. DAVIS HENRY BARTKOWSKI | 1986 | Stroke1986,,3: | 2 |
| 5 | Interference with Tissue Factor Prolongs Intrahepatic Islet Allograft Survival in a Nonhuman Primate Marginal Mass Model显示文摘 | Dora M. Berman Over Cabrera Norman M. Kenyon Joshua Miller Susan H. Tam Vrinda S. Khandekar Kristen M. Picha Avery R. Soderman Robert E. Jordan Peter J. Bugelski Denison Horninger Michael Lark Janet E. Davis Rodolfo Alejandro Per-Olof Berggren Mark Zimmer | 2007 | Transplantation2007,,3: | 1 |
| 6 | Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair显示文摘 | Tasneem Kausar Jason S. Schreiber David Karnak Leslie A. Parsels Joshua D. Parsels Mary A. Davis Lili Zhao Jonathan Maybaum Theodore S. Lawrence Meredith A. Morgan | 2015 | Neoplasia2015,,10: | 1 |
| 7 | Time and dose-dependent risk of pneumococcal pneumonia following influenza: a model for within-host interaction between influenza and Streptococcus pneumoniae显示文摘 | Sourya Shrestha Betsy Foxman Suzanne Dawid Allison E. Aiello Brian M. Davis Joshua Berus Pejman Rohani | 2013 | Journal of The Royal Society Interface2013,,86: | 1 |
| 8 | Does forgiveness require interpersonal interactions? Individual differences in conceptualization of forgiveness显示文摘 | Joshua N. Hook Everett L. Worthington Shawn O. Utsey Don E. Davis Aubrey L. Gartner David J. Jennings Daryl R. Van Tongeren Al Dueck | 2012 | Personality and Individual Differences2012,,5: | 1 |
| 9 | NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling显示文摘 | Irving C. Allen Justin E. Wilson Monika Schneider John D. Lich Reid A. Roberts Janelle C. Arthur Rita-Marie T. Woodford Beckley K. Davis Joshua M. Uronis Hans H. Herfarth Christian Jobin Arlin B. Rogers Jenny P.-Y. Ting | 2012 | Immunity2012,,5: | 1 |
| 10 | Prospective Evaluation of Fetuses With Autoimmune-Associated Congenital Heart Block Followed in the PR Interval and Dexamethasone Evaluation (PRIDE) Study显示文摘 | Deborah M. Friedman Mimi Y. Kim Joshua A. Copel Carolina Llanos Claudine Davis Jill P. Buyon | 2009 | The American Journal of Cardiology2009,,8: | 1 |
| 11 | Analytical considerations for microdialysis sampling 显示文摘 | Malonne I Davies Joshua D Cooper Serenity S Desmond | 2000 | Advanced Drug Delivery Reviews2000,45,23: | 1 |
| 12 | Computer aided music therapy evaluation:Testing the Music Therapy Logbook prototype 1 system显示文摘 | Streeter E Davies MEP Joshua D | 2012 | Psychotherapy2012,39,1: | 1 |
| 13 | 796: History of hypertension in pregnancy predicts hyperhomocysteinemia decades later显示文摘 | Wendy White Brian Brost Vesna Garovic Joshua Nitsche Jonathan O’Brien William Watson Carl Rose Norman Davies Kent Bailey Heather Wiste Stephen Turner | 2011 | American Journal of Obstetrics and Gynecology2011,,1: | 1 |
| 14 | Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776显示文摘 | Carl G. Engelke Leslie A. Parsels Yushen Qian Qiang Zhang David Karnak Jordan R. Robertson Daria M. Tanska Dongping Wei Mary A. Davis Joshua D. Parsels Lili Zhao Joel K. Greenson Theodore S. Lawrence Jonathan Maybaum Meredith A. Morgan | 2013 | Clinical Cancer Research2013,,16: | 1 |
| 15 | Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair显示文摘 | Dongping Wei Leslie A. Parsels David Karnak Mary A. Davis Joshua D. Parsels Amanda C. Marsh Lili Zhao Jonathan Maybaum Theodore S. Lawrence Yi Sun Meredith A. Morgan | 2013 | Clinical Cancer Research2013,,16: | 1 |
| 16 | Rat Middle Cerebral Artery Occlusion: Evaluation of the Model and Development of a Neurologic Examination显示文摘 | JOSHUA B. BEDERSON LAWRENCE H. PITTS MILES TSUJI MERRY C. NISHIMURA RICHARD L. DAVIS HENRY BARTKOWSKI | 1986 | Stroke1986,,3: | 1 |
| 17 | Rat Middle Cerebral Artery Occlusion: Evaluation of the Model and Development of a Neurologic Examination显示文摘 | JOSHUA B. BEDERSON LAWRENCE H. PITTS MILES TSUJI MERRY C. NISHIMURA RICHARD L. DAVIS HENRY BARTKOWSKI | 1986 | Stroke1986,,3: | 1 |
| 18 | Connecting supplier and DoD blockchains for transparent part tracking显示文摘Blockchains have been around for more than ten years,and since 2015,a plethora of systems have been launched to target more flexible use cases.More recently,several enterprise blockchain systems,such as Consensys Quorum and Hyperledger Fabric,have been launched to make blockchain simpler to apply in complex organizational configurations.In this paper,we identify a specific Department of Defense use case,extrapolate requirements,and perform a thorough assessment of the different layers of the blockchain stack to identify the existing state of the art and undertake a gap analysis of the technology for this context.We describe a platform that meets many of these challenges and show how we architected,designed,and implemented a solution for this use case for deployment at NAVAIR.This solution connects transactions from two separate blockchain systems,Consensys Quorum and Hyperledger Fabric,by using a graph-based approach that preserves privacy while enabling full transparency across the military and supplier networks. | Francis Asuncion Adam Brinckman Dwayne Cole Jeffrey Curtis Matt Davis Timothy Dunlevy Calvin Farmer Andrew Harrison Daniel P.Johnson Joshua Joyce Chris Klubertanz Jonathan Lane John Martin Jarek Nabrzyski Joel Neidig Deysi Olivares Gregory Robinson Gabriel Rodriguez Chris Root Karen Rowand Al Salour Jeff Score David Scott Ian Taylor Chandler Thompson Huy Truong Xiqun Wang Dale Warren | 2021 | Blockchain(Research and Applications)2021,2,3: | 1 |
| 19 | 职场着装法则新解显示文摘女同胞们,现在的你们还会为了吸引别人的眼球,在办公室里穿着热裤、低胸,大方地在男同事面前摇曳生姿吗?也许你们认为这样不仅能在公司获得超高的人气,而且一个不小心还能用自己的姿色顺利“上位”。然而,看了本期的《职场无忧》,你们就知道自己的想法已经很out了! | Joshua Odgen—Davis Anny(翻译) | 2014 | 疯狂英语(口语版)2014,,1: | 0 |
| 20 | 办公室恋情——你Hold得住吗?显示文摘中国有句成语叫“日久生情”。每天共处一室8小时以上的男男女女,呼吸着共同的空气,久而久之,难免会产生几分好感、几分暧昧。然而,办公室爱情并非如水晶般透明无瑕,由此带来的性骚扰、婚外情等问题不容忽视。但是,恋情来了,难以抗拒,不少人还是打算做个勇敢的人,但是有勇无谋却不行,为了让办公室恋情有个幸福结局,大家一定要谨慎待之。 | Joshua Ogden—Davis 肝脑涂地 Anny | 2013 | 疯狂英语(口语版)2013,,6: | 0 |