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| 1 | Limited endoscopic sphincterotomy plus large balloon dilation for choledocholithiasis with periampullary diverticula显示文摘AIM: To investigate the effectiveness and safety of limited endoscopic sphincterotomy (EST) plus large balloon dilation (LBD) for removing choledocholithiasis in patients with periampullary diverticula (PAD). METHODS: A total of 139 patients with common bile duct (CBD) stones were treated with LBD (10-20 mm balloon diameter) after limited EST. Of this total, 73 patients had PAD and 66 patients did not have PAD (controls). The results of stone removal and complications were retrospectively evaluated. RESULTS: There were no significant differences between the PAD and the control groups in overall successful stone removal (94.5% vs 93.9%), stone removal in first session (69.9% vs 81.8%), mechanical lithotripsy (12.3% vs 13.6%), and complications (11.0% vs 7.6%). Clinical outcomes were also similar between the types of PAD, but the rate of stone removal in first session and the number of sessions were significantly lower and more frequent, respectively, in type B PAD (papilla located near the diverticulum) than controls [23/38 (60.5%) vs 54/66 (81.8%), P = 0.021; and 1 (1-2) vs 1 (1-3), P = 0.037, respectively] and the frequency of pancreatitis was significantly higher in type A PAD (papilla located inside or in the margin of the diverticulum) than in controls (16.1% vs 3.0%, P = 0.047). CONCLUSION: Limited EST plus LBD was an effective and safe procedure for removing choledocholithiasis in patients with PAD. However, some types of PAD should be managed with caution. | Hyung Wook Kim Dae Hwan Kang Cheol Woong Choi Jong Hwan Park Jin Ho Lee Min Dae Kim Il Doo Kim Ki Tae Yoon Mong Cho Ung Bae Jeon Suk Kim Chang Won Kim Jun Woo Lee | 2010 | World Journal of Gastroenterology2010，16，34： | 26 |
| 2 | The dynamics of the piglet gut microbiome during the weaning transition in association with health and nutrition显示文摘Background: Understanding the composition of the microbial community and its functional capacity during weaning is important for pig production as bacteria play important roles in the pig's health and growth performance. However,limited information is available regarding the composition and function of the gut microbiome of piglets in early-life.Therefore, we performed 16 S rRNA gene and whole metagenome shotgun sequencing of DNA from fecal samples from healthy piglets during weaning to measure microbiome shifts, and to identify the potential contribution of the early-life microbiota in shaping piglet health with a focus on microbial stress responses, carbohydrate and amino acid metabolism.Results: The analysis of 16 S rR NA genes and whole metagenome shotgun sequencing revealed significant compositional and functional differences between the fecal microbiome in nursing and weaned piglets. The fecal microbiome of the nursing piglets showed higher relative abundance of bacteria in the genus Bacteroides with abundant gene families related to the utilization of lactose and galactose. Prevotel a and Lactobacil us were enriched in weaned piglets with an enrichment for the gene families associated with carbohydrate and amino acid metabolism. In addition, an analysis of the functional capacity of the fecal microbiome showed higher abundances of genes associated with heat shock and oxidative stress in the metagenome of weaned piglets compared to nursing piglets.Conclusions: Overal, our data show that microbial shifts and changes in functional capacities of the piglet fecal microbiome resulted in potential reductions in the effects of stress, including dietary changes that occur during weaning.These results provide us with new insights into the piglet gut microbiome that contributes to the growth of the animal. | Robin B.Guevarra Sang Hyun Hong Jin Ho Cho Bo-Ra Kim Jiwon Shin Jun Hyung Lee Bit Na Kang Young Hwa Kim Suphot Wattanaphansak Richard E.Isaacson Minho Song Hyeun Bum Kim | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 16 |
| 3 | Outcome of laparoscopic cholecystectomy is not influenced by chronological age in the elderly显示文摘AIM:To evaluate the outcome of laparoscopic cholecystectomy(LC)in patients aged 80 years and older. METHODS:A total of 353 patients aged 65 to 79 years(group 1)and 35 patients aged 80 years and older(group 2)underwent LC.Patients were further classified into two other groups:those with uncomplicated gallbladder disease(group A)or those with complicated gallbladder disease(group B). RESULTS:There were no significant differences between the age groups(groups 1 and 2)with respect to clinical characteristics such as age,gender,comorbid disease,or disease presentation.Mean operative time,conversion rate,and the incidence of major postoperative complications were similar in groups 1 and 2.However,the percentage of high-risk patients was significantly higher in group 2 than in group 1 (20.0%vs 5.7%,P<0.01).Group A comprised 322 patients with a mean age of 71.0±5.3 years,and group B comprised 51 patients with a mean age of 69.9±4.8 years.In group B,mean operative time (78.4±49.3 min vs 58.3±35.8 min,P<0.01),mean postoperative hospital stay(7.9±6.5 d vs 5.0±3.7 d, P<0.01),and the incidence of major postoperative complications(9.8%vs 3.1%,P<0.05)were significantly greater than in group A.The conversion rate tended to be higher in group B,but this difference was not significant. CONCLUSION:Perioperative outcomes in elderly patients who underwent LC seem to be influenced by the severity of gallbladder disease,and not by chronologic age.In octogenarians,LC should be performed at an earlier,uncomplicated stage of the disease whenever possible to improve perioperative outcomes. | Hyung Ook Kim Jung Won Yun Jun Ho Shin Sang Il Hwang Yong Kyun Cho Byung Ho Son Chang Hak Yoo Yong Lai Park Hungdai Kim | 2009 | World Journal of Gastroenterology2009，15，6： | 5 |
| 4 | Stereotactic body radiation therapy for inoperable hepatocellular carcinoma as a local salvage treatment after incomplete transarterial chemoembolization显示文摘 | Jin‐Kyu Kang Mi‐Sook Kim Chul Koo Cho Kwang Mo Yang Hyung Jun Yoo Jin Ho Kim Sun Hyun Bae Da Hoon Jung Kum Bae Kim Dong Han Lee Chul Ju Han Jin Kim Su Cheol Park Young Han Kim | 2012 | Cancer2012，，21： | 3 |
| 5 | Endoscopic resection yields reliable outcomes for small rectal neuroendocrine tumors显示文摘 | Joon Han Jeon Dae Young Cheung Seong Jin Lee Hyun Jin Kim Hye Kang Kim Hyung Jun Cho In Kyu Lee Jin Il Kim Soo‐Heon Park Jae Kwang Kim | 2014 | Digestive Endoscopy2014，，4： | 1 |
| 6 | Management and Outcome of Gastrointestinal Stromal Tumors of the Duodenum显示文摘 | Jun Chul Chung Chong Woo Chu Gyu Seok Cho Eung Jin Shin Chul Wan Lim Hyung Chul Kim Ok Pyung Song | 2010 | Journal of Gastrointestinal Surgery2010，，5： | 1 |
| 7 | Utilizing knowledge context in virtual collaborative work 显示文摘 | HYUNG JUN AHN HONG JOO LEE KYEHYUN CHO | 2005 | Decision Support Systems2005，39，： | 1 |
| 8 | Role of alkyl chain length and mole concentration of hydrophobic moiety in association behavior of amphiphilic polyelectrolytes in aqueous media显示文摘 | Hyung Jun Lim Eun Chul Cho Junoh Kim Ih-Seop Chang | 2006 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2006，，1： | 1 |
| 9 | The ratio of intra‐tumoral regulatory T cells (Foxp3+)/helper T cells (CD4+) is a prognostic factor and associated with recurrence pattern in gastric cardia cancer显示文摘 | Hyoung‐Il Kim Haeryoung Kim Hyoung Won Cho Sang Yong Kim Ki Jun Song Woo Jin Hyung Chung‐Gyu Park Choong‐Bai Kim | 2011 | J. Surg. Oncol2011，，7： | 1 |
| 10 | A randomized comparative study of high-dose and low-dose hepatic arterial infusion chemotherapy for intractable, advanced hepatocellular carcinoma显示文摘 | Hyun Young Woo Si Hyun Bae Jun Yong Park Kwang Hyub Han Ho Jong Chun Byung Gil Choi Hyeon U. Im Jong Young Choi Seung Kew Yoon Jae Youn Cheong Sung Won Cho Byoung Kuk Jang Jae Seok Hwang Sang Gyune Kim Young Seok Kim Yeon Seok Seo Hyung Joon Yim Soon Ho U | 2010 | Cancer Chemotherapy and Pharmacology2010，，2： | 1 |
| 11 | Analysis of conjugated heat transfer, stress and failure in a gas turbine blade with circular cooling passages显示文摘 | Kyung Min Kim Jun Su Park Dong Hyun Lee Tack Woon Lee Hyung Hee Cho | 2011 | Engineering Failure Analysis2011，，4： | 1 |
| 12 | In vitro and in vivo anti-inflammatory effect of Rhodomyrtus tomentosa methanol extract显示文摘 | Deok Jeong Woo Seok Yang Yanyan Yang Gyeongsug Nam Ji Hye Kim Deok Hyo Yoon Hyung Jun Noh Sukchan Lee Tae Woong Kim Gi-Ho Sung Jae Youl Cho | 2013 | Journal of Ethnopharmacology2013，，1： | 1 |
| 13 | Effect of polymer characteristics on structure of polymer-liposome complexes显示文摘 | Eun Chul Cho Hyung Jun Lim Jongwon Shim Ju Young Park Nily Dan Junoh Kim Ih-Seop Chang | 2007 | Journal of Colloid and Interface Science2007，311，1： | 1 |
| 14 | A randomised clinical trial of 10-day concomitant therapy and standard triple therapy for Helicobacter pylori eradication显示文摘 | Jun Heo Seong Woo Jeon Jin Tae Jung Joong Goo Kwon Eun Young Kim Dong Wook Lee Hyang Eun Seo Chang Yoon Ha Hyun Jin Kim Eun Soo Kim Kyung Sik Park Kwang Bum Cho Si Hyung Lee Byung Ik Jang | 2014 | Digestive and Liver Disease2014，，11： | 1 |
| 15 | Severe intestinal toxicity after stereotactic ablative radiotherapy for abdominopelvic malignancies显示文摘 | Sun Hyun Bae Mi-Sook Kim So Young Kim Won Il Jang Chul Koo Cho Hyung Jun Yoo Kum Bae Kim Dong Han Lee Chul Ju Han Ki Young Yang Sang Bum Kim | 2013 | International Journal of Colorectal Disease2013，，12： | 1 |
| 16 | Close observation of gastric mucosal pattern by standard endoscopy can predict H elicobacter pylori infection status显示文摘 | Jun‐Hyung Cho Young Woon Chang Jae Young Jang Jae‐Jun Shim Chang Kyun Lee Seok Ho Dong Hyo Jong Kim Byung‐Ho Kim Tae Hee Lee Joo Young Cho | 2013 | J Gastroenterol Hepatol2013，，2： | 1 |
| 17 | Association of the interval between endoscopies with gastric cancer stage at diagnosis in a region of high prevalence显示文摘 | Ji Hyung Nam Il Ju Choi Soo‐Jeong Cho Chan Gyoo Kim Jae Kwan Jun Kui Son Choi Byung‐Ho Nam Jun Ho Lee Keun Won Ryu Young‐Woo Kim | 2012 | Cancer2012，，20： | 1 |
| 18 | Hepatocellular Carcinoma in the Caudate Lobe of the Liver: Angiographic Analysis of Tumor-feeding Arteries According to Subsegmental Location显示文摘 | Chang Jin Yoon Jin Wook Chung Baik Hwan Cho Hwan Jun Jae Sung-Gwon Kang Hyo-Cheol Kim Young Ho Choi Ung Bae Jeon Jae Hyung Park | 2008 | Journal of Vascular and Interventional Radiology2008，，11： | 1 |
| 19 | Ultraviolet photodetectors based on ZnO nanoparticles显示文摘 | JUN Jin Hyung SEONG Hojun CHO Kyoungah | 2009 | Ceramics International2009，25，7： | 1 |
| 20 | A randomized comparative study of high-dose and low-dose hepatic arterial infusion chemotherapy for intractable, advanced hepatocellular carcinoma显示文摘 | Hyun Young Woo Si Hyun Bae Jun Yong Park Kwang Hyub Han Ho Jong Chun Byung Gil Choi Hyeon U. Im Jong Young Choi Seung Kew Yoon Jae Youn Cheong Sung Won Cho Byoung Kuk Jang Jae Seok Hwang Sang Gyune Kim Young Seok Kim Yeon Seok Seo Hyung Joon Yim Soon Ho U | 2010 | Cancer Chemotherapy and Pharmacology2010，，2： | 1 |
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