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| 1 | Joint contractures in severe burn patients with early rehabilitation intervention in one of the largest burn intensive care unit in China:a descriptive analysis显示文摘Background:Joint contracture is the major clinical complication in burn patients,especially,the severe burn patients.This study aimed to investigate the number and severity of joint contractures in patients with burns affecting greater than or equal to 50%of the total body surface area(TBSA)undergoing early rehabilitation in a burn intensive care unit(BICU).Methods:We analyzed burn patients with burns affecting greater than or equal to 50%of the TBSA admitted to a BICU who received early rehabilitation within 7 days post-injury from January 2011 to December 2015.Demographic and medical information was collected.The range of motion(ROM)of different joints was measured 1 month post-admission.Spearman’s correlation coefficient and logistic regression analysis was used to determine predictors of the presence and severity of contractures.Result:The average affected TBSA of the included burn patients was 67.4%,and the average length of stay in the BICU was 46.2±28.8 days.One hundred and one of 108 burn patients(93.5%)developed at least one joint contracture.The ROM in 67.9%of the affected joints was mildly limited.The majority of contractures in severe burn patients were mild(37.7%)or moderate(33.2%).The wrist was the most commonly affected joint(18.2%),followed by the shoulder,ankle,hip,knee,and elbow.A predictor of the presence of contractures was the length of hospital stay(p=0.049).The severe contracture was related to the area of full-thickness burns,the strict bed rest time,and the duration of rehabilitation in BICU.The length of rehabilitation stay(days)in patients with moderate contracture is 54.5%longer than that in severe contracture(p=0.024)Conclusion:During the long stay in BICU,the length of rehabilitation stay in a BICU could decrease the severity of contractures from severe to moderate in the patients with equal to 50%of the TBSA.Hence,this research reveals the important role of early rehabilitation interventions in severe burn patients. | Jianglin Tan Jian Chen Junyi Zhou Huapei Song Huan Deng Ming Ao Gaoxing Luo Jun Wu | 2019 | Burns & Trauma2019，7，1： | 9 |
| 2 | Enhancement of endocytic uptake of H IV-1 virions into CD4-negative epithelial cells by HIV-1 gp41 via its interaction with POB1显示文摘 | Yue Tan Junyi Wang Shan Su Qian Wang Shibo Jiang Lu Lu Ying-Hua Chen | 2017 | Cellular & Molecular Immunology2017，14，6： | 1 |
| 3 | High time-resolved imaging of targets in turbid media using uhrafast optical kerr gate 显示文摘 | Tong Junyi Tan Wenjiang Si Jinhai | 2012 | Chinese PhysicsI etters2012，29，02： | 1 |
| 4 | Stem cell niche-inspired microcarriers with ADSCs encapsulation for diabetic wound treatment显示文摘Stem cell therapies have made great progress in the treatment of diabetic wounds during recent decades,while their short in vivo residence,alloimmune reactions,undesired behaviors,and dramatic losses of cell functions still hinder the translation of them into clinic.Here,inspired by the natural components of stem cell niches,we presented novel microfluidic hydrogel microcarriers with extracellular matrix(ECM)-like composition and adipose-derived stem cells(ADSCs)encapsulation for diabetic wound healing.As the hydrogel was synthesized by conjugating hyaluronic acid methacryloyl(HAMA)onto the Fibronectin(FN)molecule chain(FN-HAMA),the laden ADSCs in the microcarriers showed improved bioactivities and pro-regenerative capabilities.Based on these features,we have demonstrated that these ADSCs microcarriers exhibited significant promotion of neovascularization,follicular rejuvenation,and collagen deposition in a mouse diabetic wound model.These results indicated that the stem cell niche-inspired FN-HAMA microcarriers with ADSCs encapsulation have great clinical potential for diabetic wound treatment. | Xiangyi Wu Haofang Zhu Junyi Che Ye Xu Qian Tan Yuanjin Zhao | 2023 | Bioactive Materials2023，，8： | 1 |
| 5 | Nitrogen and Phosphorus Pollutants Removal from Rice Field Drainage with Ecological Agriculture Ditch: A Field Case显示文摘Excessive nitrogen and phosphorus in agricultural drainage can cause a series of water environmental problems such as eutrophication of water bodies and non-point source pollution.By monitoring the water purification effect of a paddy ditch wetland in Gaochun,Nanjing,Jiangsu Province,we investigated the spatial and temporal distribution patterns of N and P pollutants in paddy drains during the whole reproductive period of rice.Then,the dynamic changes of nitrogen and phosphorus in time and space during the two processes of rainfall after basal fertilization and topdressing were analyzed after comparison.At last,the effect of the ditch wetland on nutrient purification and treatment mechanism,along with changing flow and concentration in paddy drains,was clarified.The results of this study showed that the concentrations of various nitrogen and phosphorus in the ditch basically reached the peak on the second and third days after the rainfall(5.98 mg/L for TN and 0.21 mg/L for TP),which provided a response time for effective control of nitrogen and phosphorus loss.The drainage can be purified by the ecological ditch,about 89.61%,89.03%,89.61%,98.14%,and 79.05%of TN,NH4+-N,NO3−-N,NO2−-N,and TP decline.It is more effective than natural ditches for water purification with 80.59%,40%,12.07%,91.06%and 18.42%removal rates,respectively.The results of the study can provide a theoretical basis for controlling agricultural non-point source pollution and improving the water environment of rivers and lakes scientifically. | Lina Chen Wenshuo Zhang Junyi Tan Xiaohou Shao Yaliu Qiu Fangxiu Zhang Xiang Zhang | 2022 | Phyton-International Journal of Experimental Botany2022，91，12： | 1 |
| 6 | Gastrochilus wolongensis(Orchidaceae):a new species from Sichuan,China,based on molecular and morphological data显示文摘Gastrochilus wolongensis(Orchidaceae),a new orchid species from Sichuan Province,Southwest China,is described and illustrated.It morphologically resembles G.sinensis,but differs markedly from the latter in having black-purple stripes(vs.purplish-red spots)on the adaxial side of the petals and sepals,a reniform epichile densely covered with long papillate hairs(vs.sparsely pubescent)with purplish-red spots(vs.unspotted),and outside the sac of the hypochile with purplish-red stripes(vs.purplish-red spotted).The molecular phylogenetic analysis based on nuclear ribosome internal transcribed spacer(nrITS)and four chloroplast DNA fragments(matK,psbA-trnH,psbM-trnD,and trnL-F)of 36 Gastrochilus species showed that G.wolongensis was closely related to G.ciliaris and G.formosanus. | Junyi Zhang Yuehong Cheng Min Liao Senlong Jin Chunmao Qu Yingchun Tan Anđelka Plenković-Moraj Bo Xu | 2022 | Ecosystem Health and Sustainability2022，8，1： | 0 |
| 7 | Synthesis and characterization of soluble intrinsic black polyimide with excellent comprehensive properties显示文摘Black polyimides(BPIs)have attracted increasing attention owing to their growing demand in optoelectronics.However,commonly used black polyimides doped with black fillers suffer from poor mechanical and electrical properties.To address these issues,a new diamine(2,5-bis(4′-amino-[1,1′-biphenyl]-4-yl)-3,4-bis(4-fluorophenyl)cyclopenta-2,4-dien-1-one,TPCPFPDA)bearing a tetraphenylcyclopentadienone(TPCP)moiety bonded with benzene and fluorine units was synthesized.The diamine was reacted with 4,4′-(hexafluoroisopropylidene)diphthalic anhydride(6FDA)to yield a soluble intrinsic black polyimide(TPCPFPPI).Bonding fluorine(auxochrome group)and benzene units to TPCP can increase the conjugation ofπ-electrons systems and facilitate the movement of electron throughout the bigπbond,respectively.Owing to the structural features,the synthesized TPCPFPPI exhibited complete visible-light absorption with high blackness and opacity.Its cutoff wavelength(λ_(cut))and CIE(Commission Internationale de I′Eclairage)parameter L^(*)were 684 nm and 1.33,respectively.Moreover,TPCPFPPI displayed exceptional electrical,mechanical,and thermal properties as well as excellent solubility.A detailed theoretical calculation was conducted to gain better insight into the electronic properties of the TPCPFPPI.Results showed that the blackness of TPCPFPPI was chiefly attributed to the electron transition from highest occupied molecular orbital(HOMO)to lowest unoccupied molecular orbital(LUMO)in the diamines,where the charges primarily migrated from the aryl groups in the 2-and 5-positions to the cyclopentadienone center.The as-obtained intrinsic BPI(TPCPFPPI),exhibiting both high solubility and outstanding overall properties,has important applications in photo-electronics. | TAN JingHua SHEN JunYi HUANG Jie ZHAO ChunBo LI HuiPeng LIU XueYuan XIE FengYun LIU YiWu | 2023 | Science China(Technological Sciences)2023，66，12： | 0 |
| 8 | Activated mouse CD4+Foxp3- T cells facilitate melanoma metastasis via Qa-1-dependent suppression of NK-cell cytotoxicity显示文摘 | Xiaojuan Wang Yanyan Cui Gaoxmg Luo Qinghong Wang Jie Hu Weifeng He Jun Yuan Junyi Zhou Yan Wu Xiaofeng Sun Simon C Robson Xianchang Li Jiangling Tan Yanmeng Peng Gang Xue Linrong Lu Wenda Gao Jun Wu | 2012 | Cell Research2012，22，12： | 0 |
| 9 | Exploring the psychological impact of the 2022 SARS-CoV-2 Omicron variant outbreak in China显示文摘To the editor:The impact of the coronavirus disease 2019(COVID-19)pandemic in 2020 on mental health was substantialin Chinai2and various other countries.34 Beyond the direct consequences of COVID-19,the pandemic created an environment in which many determinants of mental health were affected.Issues associated with the pandemic,such as loss of livelihood,limited access to medical services,reduced social interactions,and economic downturn,could potentially have adverse effects on the population's mental well-being.5 In November 2021,the World Health Organization(WHO)designated the new variant of the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),variant B.1.1.529,as a variant of concern and named it Omicron;its rapid mutation and spread raised a new global health concern. | Gangbin Han Guirong Cheng Feifei Hu Chunli Li Dan Liu Juan Zhou Jing Liu Linya Huang Xiaochang Liu Qianqian Nie Dan Song Deyang Zeng Lang Xu Jinquan Li Yushan Chen Zhen Wei Qiong Wu Xiaoming He Qingming Wu Wei Tan Yufei Mei Xingxing Chen Yangming Ou Jingjing ZhangYafu Yu Mengliu Yang Pengfei Lian Fukai Zhou Renjia Fan Hong Wan Chenlu Hu Yidi Fu Shiyue Li Junyi Wang Cheng Cai Mengdie Pei Yuyang Cui Wanying Cai Yiqing Li Shiyao Pan Chang Chen Yan He Zhaoxia Wu Liu Hu Liang Tao Hongyan Xiao Xinyan Xie Yan Zeng | 2023 | General Psychiatry2023，36，6： | 0 |
| 10 | ORYZA SATIVA SPOTTED-LEAF 41(OsSPL41) Negatively Regulates Plant Immunity in Rice显示文摘Identification of immunity-associated leucine-rich repeat receptor-like protein kinases(LRR-RLK) is critical to elucidate the LRR-RLK mediated mechanism of plant immunity.Here,we reported the map-based cloning of a novel rice SPOTTED-LEAF 41(Os SPL41) encoding a putative LRR-RLK protein(Os LRR-RLK41/Os SPL41) that regulated disease responses to the bacterial blight pathogen Xanthomonas oryzae pv.oryzae(Xoo).An 8-bp insertion at position 865 bp in a mutant spotted-leaf 41(spl41) allele led to the formation of purple-brown lesions on leaves.Functional complementation by the wild type allele(Os SPL41) can rescue the mutant phenotype,and the complementary lines showed similar performance to wild type in a number of agronomic,physiological and molecular indices.Os SPL41 was constitutively expressed in all tissues tested,and Os SPL41 contains a typical transmembrane domain critical for its localization to the cell membrane.The mutant exhibited an enhanced level of resistance to Xoo in companion of markedly up-regulated expression of pathogenesis-related genes such as Os PR10a,Os PAL1 and Os NPR1,while the level of salicylic acid was significantly increased in spl41.In contrast,the over-expression lines exhibited a reduced level of H_(2)O_(2) and were much susceptible to Xoo with down-regulated expression of pathogenesis-related genes.These results suggested that Os SPL41 might negatively regulate plant immunity through the salicylic acid signaling pathway in rice. | TAN Jingyi ZHANG Xiaobo SHANG Huihui LI Panpan WANG Zhonghao LIAO Xinwei XU Xia YANG Shihua GONG Junyi WU Jianli | 2023 | Rice science2023，30，5： | 0 |
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