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1Association of Helicobacter pylori infection with colorectal polyps and malignancy in China显示文摘BACKGROUND Gastric Helicobacter pylori(H.pylori)infection is related to chronic gastritis,gastroduodenal ulcer,and gastric malignancies;whether this infection is related to colorectal polyps and colorectal cancer(CRC),remains debatable.AIM To investigate the relationship between gastric H.pylori infection and the risk of colorectal polyps and CRC.METHODS We retrospectively analyzed 3872 patients with colorectal polyps who underwent colonoscopy and pathological diagnosis.We also analyzed 304 patients with primary CRC.The characteristics of these patients were compared with those of the control group,which included 2362 patients with the normal intestinal mucosa.All subjects completed a 14C-urea breath test,bidirectional gastrointestinal endoscopy,and a biopsy on the same day.Data on the number,size,location,and pathology of the polyps,the location,and pathology of the CRC,the detection of H.pylori,and the incidence of H.pylori-associated atrophic gastritis or intestinal metaplasia were obtained.A logistic regression model was used to analyze the relationship between gastric infection due to H.pylori,and the incidence of colorectal polyps and CRC.RESULTS The prevalence of H.pylori infection was higher in the multiple polyps group than in the solitary polyp group and the control group[95%confidence interval(CI)=1.02-1.31,P=0.03;95%CI:2.12-2.74,P<0.001].The patients with adenomatous polyps had a higher incidence of H.pylori infection than patients with non-adenomatous polyps[59.95%vs 51.75%,adjusted odds ratio(OR)=1.41,95%CI:1.24-1.60,P<0.01].Patients with H.pylori-associated atrophic gastritis or intestinal metaplasia were at high risk of CRC(adjusted OR=3.46,95%CI:2.63-4.55,P<0.01;adjusted OR=4.86,95%CI:3.22-7.34,P<0.01,respectively).The size and location of the polyps,the histopathological characteristics and the location of CRC were not related to H.pylori infection.CONCLUSION Our study demonstrates that the incidence of gastric H.pylori infection and H.pylori-associated atrophic gastritis or intestinal metaplasia elevates the risk of colorectal polyps and CRC.Man Wang Wen-Jie Kong Jing-Zhan Zhang Jia-Jie Lu Wen-Jia Hui Wei-Dong Liu Xiao-Jing Kang Feng Gao 2020World Journal of Gastrointestinal Oncology2020,12,5:15
2A rapid method for chemical fingerprint analysis of Panax notoginseng powders by ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry显示文摘A method coupling ultra-performance liquid chromatography(UPLC) with quadrupole time-of-flight mass spectrometer(Qtof MS) using the electrospray ionization(ESI) source was developed for the identification of the major saponins from Panax notoginseng powder(PNP). Ten different PNP samples were analyzed and evaluated for their quality by similarity evaluation and principle component analysis(PCA). Based on the accurate mass, summarized characteristic fragmentation behaviors, retention times of different types of saponins, related botanical biogenesis, and reported chromatographic behavior of saponins, fifty-one common peaks were effectively separated and identified, including 28 protopanaxadiol saponins and 18 protopanaxatriol saponins. Simultaneously, 15 significant discrepancy compounds were identified from the disqualified PNP samples. The established UPLC/Qtof MS fingerprint method was successfully applied for profiling and identifying the major saponins of PNP, providing a fast quality evaluation tool for distinguishing the authentic PNP and the adulterated products.LIU Peng YU He-Shui ZHANG Li-Juan SONG Xin-Bo KANG Li-Ping LIU Jing-Yuan ZHANG Jie CAO Man YU Kate KANG Ting-Guo MA Bai-Ping 2015Chinese Journal of Natural Medicines2015,13,6:13
3Multicenter Evaluation of the Molecular Line Probe Assay for Multidrug Resistant Mycobacterium Tuberculosis Detection in China显示文摘In order to evaluate the performance of a molecular Hain line probe assay(Hain LPA)for rapid detection of rifampicin and isoniazid resistance of Mycobacterium tuberculosis in China。LI Qiang DONG Hai Yan PANG Yu XIA Hui OU Xi Chao ZHANG Zhi Ying LI Jun Chen ZHANG Jian Kang HUAN Shi Tong CHIN Daniel P KAM Kai Man ZHAO Yan Lin 2015Biomedical and Environmental Sciences2015,28,6:13
4Intravoxel incoherent motion diffusion-weighted imaging for monitoring chemotherapeutic efficacy in gastric cancer显示文摘AIM: To assess intravoxel incoherent motion diffusionweighted imaging(IVIM-DWI) for monitoring early efficacy of chemotherapy in a human gastric cancer mouse model.METHODS: IVIM-DWI was performed with 12 b-values(0-800 s/mm2) in 25 human gastric cancer-bearing nude mice at baseline(day 0), and then they were randomly divided into control and 1-, 3-, 5- and 7-d treatment groups(n = 5 per group). The control group underwent longitudinal MRI scans at days 1, 3, 5 and 7, and the treatment groups underwent subsequent MRI scans after a specified 5-fluorouracil/calciumfolinate treatment. Together with tumor volumes(TV), the apparent diffusion coefficient(ADC) and IVIM parameters [true water molecular diffusion coefficient(D), perfusion fraction(f) and pseudo-related diffusion coefficient(D*)] were measured. The differences in those parameters from baseline to each measurement(ΔTV%, ΔADC%, ΔD%, Δf% and ΔD*%) were calculated. After image acquisition, tumor necrosis, microvessel density(MVD) and cellular apoptosis were evaluated by hematoxylin-eosin(HE), CD31 and terminal-deoxynucleotidyl transferase mediated nick end labeling(TUNEL) staining respectively, to confirm the imaging findings. Mann-Whitney test and Spearman's correlation coefficient analysis were performed.RESULTS: The observed relative volume increase(ΔTV%) in the treatment group were significantly smaller than those in the control group at day 5(ΔTV_(treatment)% = 19.63% ± 3.01% and ΔTVcontrol% = 83.60% ± 14.87%, P = 0.008) and day 7(ΔTV_(treatment)% = 29.07% ± 10.01% and ΔTV_(control)% = 177.06% ± 63.00%, P = 0.008). The difference in ΔTV% between the treatment and the control groups was not significant at days 1 and 3 after a short duration of treatment. Increases in ADC in the treatment group(ΔADC%_(treatment), median, 30.10% ± 18.32%, 36.11% ± 21.82%, 45.22% ± 24.36%) were significantly higher compared with the control group(ΔADC%_(control), median, 4.98% ± 3.39%, 6.26% ± 3.08%, 9.24% ± 6.33%) at days 3, 5 and 7(P = 0.008, P = 0.016, P = 0.008, respectively). Increases in D in the treatment group(ΔD%_(treatment), median 17.12% ± 8.20%, 24.16% ± 16.87%, 38.54% ± 19.36%) were higher than those in the control group(ΔD%_(control), median-0.13% ± 4.23%, 5.89% ± 4.56%, 5.54% ± 4.44%) at days 1, 3, and 5(P = 0.032, P = 0.008, P = 0.016, respectively). Relative changes in f were significantly lower in the treatment group compared with the control group at days 1, 3, 5 and 7 follow-up(median,-34.13% ± 16.61% vs 1.68% ± 3.40%, P = 0.016;-50.64% ± 6.82% vs 3.01% ± 6.50%, P = 0.008;-49.93% ± 6.05% vs 0.97% ± 4.38%, P = 0.008, and-46.22% ± 7.75% vs 8.14% ± 6.75%, P = 0.008, respectively). D* in the treatment group decreased significantly compared to those in the control group at all time points(median,-32.10% ± 12.22% vs 1.85% ± 5.54%, P = 0.008;-44.14% ± 14.83% vs 2.29% ± 10.38%, P = 0.008;-59.06% ± 19.10% vs 3.86% ± 5.10%, P = 0.008 and-47.20% ± 20.48% vs 7.13% ± 9.88%, P = 0.016, respectively). Furthermore, histopathologic findings showed positive correlations with ADC and D and tumor necrosis(r_s = 0.720, P < 0.001; r_s = 0.522, P = 0.007, respectively). The cellular apoptosis of the tumor also showed positive correlations with ADC and D(r_s = 0.626, P = 0.001; r_s = 0.542, P = 0.005, respectively). Perfusionrelated parameters(f and D*) were positively correlated to MVD(r_s = 0.618, P = 0.001; r_s = 0.538, P = 0.006, respectively), and negatively correlated to cellular apoptosis of the tumor(r_s =-0.550, P = 0.004; r_s =-0.692, P < 0.001, respectively).CONCLUSION: IVIM-DWI is potentially useful for predicting the early efficacy of chemotherapy in a human gastric cancer mouse model.Xiao-Li Song Heoung Keun Kang Gwang Woo Jeong Kyu Youn Ahn Yong Yeon Jeong Yang Joon Kang Hye Jung Cho Chung Man Moon 2016World Journal of Gastroenterology2016,22,24:12
5The ultratrace detection of crystal violet using surface enhanced Raman scattering on colloidal Ag nanoparticles prepared by electrolysis显示文摘高度活跃、稳定、买得起的表面提高了散布的拉曼(重量的单位)底层被 electrolyzing 获得 AgNO 3的混合物( 4 × ; 10 −4 mol/L )并且 Na 3 C 6 H 5 O 7·H2 O ( 6 × ; 10 −5 mol/L )为 1 ,在 7 V 的 2 , 3 和 4 h 。与水晶紫(CV ) 作为一个测试分子,有 785 nm 激光刺激的一个便携式的拉曼分光计被采用执行 SERS 察觉。胶体的 Ag nanoparticles 与粒子尺寸为 3 h 由 electrolyzing 准备了(65 ± 17 ) nm 是为 CV 的极端踪迹察觉的完美的重量的单位底层,它显示了 ca 的一个改进因素。1.3 × 10 8 和 CV 的察觉限制对 ca 感到不满。10 −15 mol/L (ca。10 −4 ppb ) 与是的 10 −1 mol/L KBr 聚集代理人。因此,这重量的单位底层将在极端踪迹察觉提供有希望的前景。同时,从实验室带给拉曼分析在 situ,即时察觉和鉴定处理将提供可能性。Ren Ming Liu Yi Pu Kang Xing Fa Zi Ming Jun Feng Man Cheng Min Zhen Si 2009Chinese Chemical Letters2009,20,6:10
6Soil erosion of unpaved loess roads subjected to an extreme rainstorm event: a case study of the Jiuyuangou watershed on the Loess Plateau, China显示文摘Rainfall can cause serious soil loss in the Loess Plateau hilly and gully region, but little focus has been placed on the extreme rainstorm effects on unpaved loess road soil erosion. A field survey method was used to investigate the erosional effects of the '7·26' heavy rainfall event on unpaved loess roads in the Jiuyuangou watershed of the Loess Plateau, China. The results showed that the average and maximum widths of the eroded gullies that formed on the unpaved roads were 0.65-1.48 m and 1.00-3.60 m, respectively. The average and maximum depths of theeroded gullies were 0.42-1.13 m and 0.75-4.30 m, respectively. The average width-to-depth ratio was 1.31, indicating that the widening effect was greater than the downcutting effect in the eroded gullies. In addition, the gully density ranged from 0.07 to 0.29 m m-2, and the road surface dissection degree ranged from 0.03 to 0.41 km2 km-2. Eroded gullies generally developed at the slope toe of the cut bank side. The average eroded gully width and depth at turns in the road were 1.47-2.64 times and 1.30-3.47 times greater, respectively, than those in other road sections. The road erosion modulus increased from the upper section to the lower section of the roads. The average road erosion modulus of the study catchment was 235,000 t km-2. Turns in the road were associated with collapses, sinkholes and other gravitational erosion phenomena. The amount of road erosion under extreme rainfall conditions is mainly related to the interactions among road length, width, slope and soil bulk density. Our results provide a useful reference for developing further measures for preventing road erosion on the Loess Plateau.YANG Bo WANG Wen-long GUO Ming-ming GUO Wen-zhao WANG Wen-xin KANG Hong-liang ZHAO Man CHEN Zhuo-xin 2019Journal of Mountain Science2019,16,6:8
7Hepatic resection vs percutaneous radiofrequency ablation of hepatocellular carcinoma abutting right diaphragm显示文摘BACKGROUND It is usually difficult to adequately conduct percutaneous ultrasound-guided radiofrequency(RF) ablation for hepatocellular carcinomas(HCCs) abutting the diaphragm. Our hypothesis was that the subphrenic location of HCC could have an effect on the long-term therapeutic outcomes after hepatic resection and RF ablation.AIM To compare the long-term therapeutic outcomes of hepatic resection and percutaneous RF ablation for HCCs abutting the diaphragm.METHODS A total of 143 Child-Pugh class A patients who had undergone hepatic resection(n = 80) or percutaneous ultrasound-guided RF ablation(n = 63) for an HCC(≤ 3 cm) abutting the right diaphragm were included. Cumulative local tumor progression(LTP), cumulative intrahepatic distant recurrence(IDR), disease-free survival(DFS), and overall survival(OS) rates were estimated. Prognostic factors for DFS and OS were analyzed. Complications were evaluated.RESULTS The cumulative IDR rate, DFS rate, and OS rate for the hepatic resection group and RF ablation group at 5 years were '35.9% vs 65.8%', '64.1% vs 18.3%', and'88.4% vs 68.7%', respectively. Hepatic resection was an independent prognostic factor for DFS(P ≤ 0.001; hazard ratio, 0.352; 95%CI: 0.205, 0.605; with RF ablation as the reference category); however, treatment modality was not an independent prognostic factor for OS. The LTP rate was 46.6% at 5 years for the RF ablation group. The major complication rate was not significantly different between the groups(P = 0.630). The rate of occurrence of peritoneal seeding was higher in the RF ablation group(1.3% vs 9.5%, P = 0.044).CONCLUSION Although OS was not significantly different between patients who had gone hepatic resection or percutaneous RF ablation for HCCs abutting the diaphragm,DFS was better in the hepatic resection group.Kyoung Doo Song Hyo Keun Lim Hyunchul Rhim Min Woo Lee Tae Wook Kang Yong Han Paik Jong Man Kim Jae-Won Joh 2019World Journal of Gastrointestinal Oncology2019,11,3:6
8Spider web-like carbonized bacterial cellulose/MoSe_(2) nanocomposite with enhanced microwave attenuation performance and tunable absorption bands显示文摘It is essential to manufacture microwave absorbers with strong absorption as well as tunable absorption bands at a low filler content.However,it remains challenging for pure biomass material to reach this goal without loading other components.MoSe_(2),as a transition metal chalcogenide with semiconductor properties,has emerged as a potential microwave absorber filler.Herein,bacterial cellulose(BC)-derived carbon nanofibers/MoSe_(2) nanocomposite was fabricated and phosphoric acid was used to dope phosphorus in BC,in which MoSe_(2) microspheres were dropped on the BC network like a dew-covered spider web.This unique network structure enhances conductive loss and multiple reflections of the incident wave.The collocation of BC and MoSe_(2) is helpful to impedance match and introduces interfacial/dipolar polarization loss;moreover,the P-doping of BC helps to tune the absorption bands.Overall,the optimal reflection loss of undoped one reaches−53.33 dB with only 20 wt.%filler content,whose main absorption peaks focus on X-band.Interestingly,after the P-doping of BC,the main absorption peaks move to Ku-band and the optimal reflection loss gets stronger(−66.84 dB)with the same filler loading.Strong absorption and tunable absorption bands can be realized,and thus wide frequency range is covered.This work is expected to enlighten future exploration of biomass carbon materials on high-performance microwave absorption materials.Zhengjian Xu Man He Yuming Zhou Shuangxi Nie Yongjuan Wang Yao Huo Yifan Kang Ruili Wang Ran Xu Hao Peng Xi Chen 2021Nano Research2021,14,3:6
9Pharmacokinetic study of single and multiple oral dose administration of antofloxacin hydrochloride in healthy male volunteers显示文摘背景 A 新 fluroquinolone 抗菌剂代理人, antofloxacin hydrochloride ,在中国发展了,学习的 levofloxacin.The 目的 8-NH2 derivant 是用汉语评估 antofloxacin hydrochloride 的单个、多重的口头的剂量的 pharmacokinetic 特征健康的男 volunteers.Methods 一开标签,非使随机化,单个、多重的剂量临床的试用是 conducted.In 单身者剂量学习, 12 个题目拿了 200 mg antofloxacin hydrochloride.In 多重剂量学习, 12LU Yuan KANG Zi-sheng ZHU Yan ZHANG Ming LIU Yan ZHANG Man LI Tian-yun XIAO Yong-hong 2011Chinese Medical Journal2011,,2:6
10Inorganic Elemental Determinations of Marine Traditional Chinese Medicine Meretricis concha from Jiaozhou Bay:The construction of Inorganic Elemental Fingerprint Based on Chemometric Analysis显示文摘The goal of this paper is to explore the relationship between the inorganic elemental fingerprint and the geographical origin identification of Meretricis concha,which is a commonly used marine traditional Chinese medicine(TCM) for the treatment of asthma and scald burns.For that,the inorganic elemental contents of Meretricis concha from five sampling points in Jiaozhou Bay have been determined by means of inductively coupled plasma optical emission spectrometry,and the comparative investigations based on the contents of 14 inorganic elements(Al,As,Cd,Co,Cr,Cu,Fe,Hg,Mn,Mo,Ni,Pb,Se and Zn) of the samples from Jiaozhou Bay and the previous reported Rushan Bay were performed.It has been found that the samples from the two bays are approximately classified into two kinds using hierarchical cluster analysis,and a four-factor model based on principle component analysis could explain approximately 75% of the detection data,also linear discriminant analysis can be used to develop a prediction model to distinguish the samples from Jiaozhou Bay and Rushan Bay with accuracy of about 93%.The results of the present investigation suggested that the inorganic elemental fingerprint based on the combination of the measured elemental content and chemometric analysis is a promising approach for verifying the geographical origin of Meretricis concha,and this strategy should be valuable for the authenticity discrimination of some marine TCM.SHAO Mingying LI Xuejie ZHENG Kang JIANG Man YAN Cuiiwe LI Yantuan 2016Journal of Ocean University of China2016,15,2:5
11Single hepatocellular carcinoma ≤ 3 cm in left lateral segment:Liver resection or radiofrequency ablation?显示文摘AIM:To evaluate the long-term results of radiofrequency ablation(RFA)compared to left lateral sectionectomy(LLS)in patients with Child-Pugh class A disease for the treatment of single and small hepatocellular carcinoma(HCC)in the left lateral segments.METHODS:We retrospectively reviewed the data of133 patients with single HCC(≤3 cm)in their left lateral segments who underwent curative LLS(n=66)or RFA(n=67)between 2006 and 2010.RESULTS:The median follow-up period was 33.5mo in the LLS group and 29 mo in the RFA group(P=0.060).Most patients had hepatitis B virus-related HCC.The hospital stay was longer in the LLS group than in the RFA group(8 d vs 2 d,P<0.001).The 1-,2-,and 3-year disease-free survival and overall survival rates were 80.0%,68.2%,and 60.0%,and 95.4%,92.3%,and 92.3%,respectively,for the LLS group;and 80.8%,59.9%,and 39.6%,and 98.2%,92.0%,and 74.4%,respectively,for the RFA group.The disease-free survival curve and overall survival curve were higher in the LLS group than in the RFA group(P=0.012 and P=0.013,respectively).Increased PIVKA-Ⅱlevels and small tumor size were associated with HCC recurrence in multivariate analysis.CONCLUSION:Liver resection is suitable for single HCC≤3 cm in the left lateral segments.Jong Man Kim Tae Wook Kang Choon Hyuck David Kwon Jae-Won Joh Justin Sangwook Ko Jae Berm Park Hyunchul Rhim Joon Hyeok Lee Sung Joo Kim Seung Woon Paik 2014World Journal of Gastroenterology2014,20,14:4
12Analysis of interprovincial trade embodied carbon emissions in Beijing-Tianjin-Hebei and surrounding provinces: based on constructed MRIO Model显示文摘The interprovincial trade embodied carbon emissions plays an important role in the national emission reduction target among China's provinces. Furthermore, it will affect the smooth start-up of the national carbon trade market as well as the implementation of targets in 2030 for dealing with the climate change. Based on constructed MRIO model, this paper analyzes the embodied carbon emission trade flows among Beijing, Tianjin, Hebei and surrounding regions such as Shanxi, Shaanxi, and Inner Mongolia. The results indicate that six provinces have formed different patterns of carbon trade balance, where Beijing, Tianjin, and Hebei provinces are in a deficit position, while the other three provinces are in a surplus position.Beijing, Tianjin, and Hebei have transferred part of the carbon emissions to the other three provinces, which shows greater heterogeneity among various provinces and provincial different sectors. On basis of the conclusions, this paper puts forward some suggestions on provincial decomposition, responsibility distribution, and provincial collaborative reduction for national emission reduction targets.Jianhui Cong Qingyan Liu Jidong Kang Wenju Li Xiaopei Wang Man Li 2017Chinese Journal of Population,Resources and Environment2017,15,1:4
13Outcome of catheter ablation of atrial fibrillation in patients with prior ischemic stroke显示文摘LI Song-nan KANG Jun-ping DU Xin HE Xiao-nan LONG De-yong YU Rong-hui TANG Ri-bo SANG Cai-hua JIANG Chen-xi NING Man DONG Jian-zeng MA Chang-sheng 2013Chinese Medical Journal2013,,6:4
14Clinical characteristics of sentinel polyps and their correlation with proximal colon cancer: A retrospective observational study显示文摘BACKGROUND Colorectal cancer is a common malignant tumor of the digestive tract.The relationship between sentinel polyps(rectal polyps with proximal colon cancer)and proximal colon cancer has received extensive attention in recent years.However,there is still no clear conclusion regarding the relationship.AIM To investigate the clinical characteristics of sentinel polyps and their correlation with proximal colon cancer.METHODS A retrospective analysis of 2587 patients with rectal polyps from January 2006 to December 2017 was performed.According to whether or not proximal colon cancer was diagnosed,the patients were divided into either a sentinel polyp group(192 patients)or a pure rectal polyp group(2395 patients).The endoscopic features,clinicopathological features,therapeutic effects,and short-term prognosis were analyzed and compared between the two groups.RESULTS The mean age of patients in the sentinel polyp group was generally higher than that of the pure rectal polyp group,and the positivity rates of anemia,stool occult blood,and tumor markers of the sentinel polyp group were also significantly higher than those in the rectal polyp group(χ^2=90.56,P<0.01;χ^2=70.30,P<0.01;χ^2=92.80,P<0.01).The majority of the patients in the sentinel polyp group had multiple polyps,large polyps,adenomatous polyps,or sessile polyps(χ^2=195.96,P<0.01;χ^2=460.46,P<0.01;χ^2=94.69,P<0.01;χ^2=48.01,P<0.01).Most of the proximal colon cancers were Duke’s A and B stages in the sentinel polyp group.In the pure rectal polyp group,2203 patients underwent endoscopic treatment,and all of the patients were cured and discharged.In the sentinel polyp group,65 patients underwent radical operation,and 61 patients received endoscopic submucosal dissection or endoscopic mucosal resection.Additionally,21 patients were lost to follow-up after 6-12 mo,and the loss rate was 10.94%.A total of 63.16%of patients experienced remission without tumor recurrence or metastasis,33.33%of patients experienced tumors regression or improved symptoms,and the other 3.51%of the patients died.CONCLUSION If there are multiple,sessile,and adenomatous rectal polyps with a maximum diameter>1 cm,the possibility of the carcinogenesis of the polyps or of the proximal colon should be monitored closely.These patients should be followed in the short-term and should undergo a whole-colon examination.Man Wang Jia-Jie Lu Wen-Jie Kong Xiao-Jing Kang Feng Gao 2019World Journal of Clinical Cases2019,7,20:4
15Evolution of dielectric loss-dominated electromagnetic patterns in magnetic absorbers for enhanced microwave absorption performances显示文摘As the growing criterion of electromagnetic wave (EMW) absorption materials, micro/nano-scale magnetic materials are drawing more and more attention for their unique features compared to bulky absorbers. Generally, the complex permeability of micro/nano-scale magnetic absorbers varies in a relatively narrow range, whatever for the storage of magnetic energy or the dissipation of magnetic energy. If so, how the small variation of permeability affects the ultimate performances is still unclear. Here, a strategy of electromagnetic parameters regulation for the magnetic materials is applied to understand the loss contribution in micro/nanoscale magnetic absorbers. After analyzing the evolution of electromagnetic maps of ten ferrosoferric oxide samples, it can be found that the dissipation contribution of permeability for magnetic materials is weaker than that of permittivity, in spite of its significant role in determining the impedance matching characteristics. In summary, this work systematically explores the loss contribution in micro/nano-magnetic absorbers for the first time, which is of great importance in designing and optimizing the microwave absorption properties of magnetic absorbers.Xiaogu Huang Man Qiao Xiaochi Lu Yafei Li Yabin Ma Bo Kang Bin Quan Guangbin Ji 2021Nano Research2021,14,11:4
16Study on repairing canine mandibular defect with porous Mg-Sr alloy combined with Mg-Sr alloy membrane显示文摘To discuss the feasibility of the application of porous Mg-Sr alloy combined with Mg-Sr alloy membrane in the repair of mandibular defects in dogs.The second and third mandibular premolars on both sides were extracted from six dogs.The model of mandible buccal fenestration bone defects were prepared after the sockets healed.Twelve bone defects were randomly divided into groups A and B,then Mg-Sr alloy was implanted in bone defects of group A and covered by Mg-Sr alloy membrane while Mg-Sr alloy was implanted in bone defects of group B and covered by mineralized collagen membrane.Bone defects observed on cone beam computed tomographic images and comparing the gray value of the two groups after 4,8 and 12 weeks.After 12 weeks,the healing of bone defects were evaluated by gross observation,X-ray microscopes and histological observation of hard tissue.Bone defects in each group were repaired.At 8 and 12 weeks,the gray value of group A was higher than that of group B(P<0.05).At 12 weeks,the bone volume fraction of group A was higher than that of group B(P<0.05).The newly woven bone in group A is thick and arranged staggered,which was better than that of group B.Porous Mg-Sr alloy combined with Mg-Sr alloy membrane could further promote the repair of mandibular defects,and obtain good osteogenic effect.Shanning Zhang Xirao Sun Chunyu Kang Man Yang Yuan Zhao Chengyue Wang 2020Regenerative Biomaterials2020,7,3:3
17Inhibition of matrix metalloproteinases expression in human dental pulp cells by all-trans retinoic acid显示文摘All-trans retinoic acid(ATRA) inhibits matrix metalloproteinase(MMP)-2 and MMP-9 in synovial fibroblasts, skin fibroblasts,bronchoalveolar lavage cells and cancer cells, but activates MMP-9 in neuroblast and leukemia cells. Very little is known regarding whether ATRA can activate or inhibit MMPs in human dental pulp cells(HDPCs). The purpose of this study was to determine the effects of ATRA on the production and secretion of MMP-2 and-9 in HDPCs. The productions and messenger RNA(mRNA) expressions of MMP-2 and-9 were accessed by gelatin zymography and real-time polymerase chain reaction(PCR), respectively. ATRA was found to decrease MMP-2 level in a dose-dependent manner. Significant reduction in MMP-2 mRNA expression was also observed in HDPCs treated with 25 mmol?L21ATRA. However, HDPCs treated with ATRA had no effect on the pattern of MMP-9 produced or secreted in either cell extracts or conditioned medium fractions. Taken together, ATRA had an inhibitory effect on MMP-2 expression in HDPCs,which suggests that ATRA could be a candidate as a medicament which could control the inflammation of pulp tissue in vital pulp therapy and regenerative endodontics.Jin Man Kim Sang Wook Kang Su-Mi Shin Duck Su Kim Kyong-Kyu Choi Eun-Cheol Kim Sun-Young Kim 2014International Journal of Oral Science2014,6,3:3
18Differential Analysis of ARX Block Ciphers Based on an Improved Genetic Algorithm显示文摘Differential cryptanalysis is one of the most critical analysis methods to evaluate the security strength of cryptographic algorithms.This paper first applies the genetic algorithm to search for differential characteristics in differential cryptanalysis.A new algorithm is proposed as the fitness function to generate a high-probability differential characteristic from a given input difference.Based on the differential of the differential characteristic found by genetic algorithm,Boolean satisfiability(SAT)is used to search all its differential characteristics to calculate the exact differential probability.In addition,a penalty-like function is also proposed to guide the search direction for the application of the stochastic algorithm to differential cryptanalysis.Our new automated cryptanalysis method is applied to SPECK32 and SPECK48.As a result,the 10-round differential probability of SPECK32 is improved to 2^(−30.34),and a 12-round differential of SPECK48 with differential probability 2−46.78 is achieved.Furthermore,the corresponding differential attacks are also performed.The experimental results show our method’s validity and outstanding performance in differential cryptanalysis.KANG Man LI Yongqiang JIAO Lin WANG Mingsheng 2023Chinese Journal of Electronics2023,32,2:3
19Norovirus Infection and Histo-blood Group Antigens in Children Hospitalized with Diarrhea in Lulong and Chenzhou in China显示文摘Norovirus(No V)is a pathogen that commonly causes viral diarrhea in children.Studies indicate that No V recognizes human histo-blood group antigens(HBGAs)as cell attachment factors.In order to explore the correlation between of No V infection and HBGAs,a cross-sectional study was conducted in children less than five years old who were hospitalized with diarrhea in two areas of China between November 2014 and February 2015.SUN Xiao Man YAN Xiao Feng HE Zhi Gang Li Jing Xin GUO Ni Jun XU Zi Qian JIN Miao LI Dan Di ZHOU Yong Kang XIE Guang Cheng Pang Li Li ZHANG Qing LIU Na DUAN Zhao Jun 2016Biomedical and Environmental Sciences2016,29,4:3
20Skeletal muscle mass to visceral fat area ratio is associated with metabolic syndrome and arterial stiffness: The Korean Sarcopenic Obesity Study (KSOS)显示文摘Tae Nyun Kim Man Sik Park Kang Il Lim Sae Jeong Yang Hye Jin Yoo Hyun Joo Kang Wook Song Ji A. Seo Sin Gon Kim Nan Hee Kim Sei Hyun Baik Dong Seop Choi Kyung Mook Choi 2011Diabetes Research and Clinical Practice2011,,2:2
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