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| 1 | First identification of kdr allele F1534S in VGSC gene and its association with resistance to pyrethroid insecticides in Aedes albopictus populations from Haikou City,Hainan Island,China显示文摘Background:Aedes albopictus is distributed widely in China,as a primary vector of Dengue fever and Chikungunya fever in south of China.Chemical insecticide control is one of the integrated programmes to prevent mosquito-borne diseases.Long-term applications of pyrethroids have resulted in the development of resistance in Ae.albopictus populations in China.However,the susceptibility of Ae.albopictus to pyrethroids in Hainan Island was unclear.Knockdown resistance(kdr),caused by point mutations in the VGSC gene,is one of the mechanisms that confer resistance to DDT and pyrethroids.This study was to investigate the resistance level of Ae.albopictus populations in Haikou City to three pyrethroid insecticides,and elucidate the relationship between the resistant phenotype and kdr mutations.Methods:The Aedes albopictus samples were collected in Xinbu Island(XI),Longtang Town(LT),Shishan Town(ST),Baishamen Park(BP),and Flower Market(FM)from Haikou City,Hainan Island,China.The larval susceptibility to deltamethrin,permethrin and beta-cypermethrin was tested by larval bioassays,and adult susceptibility to deltamethrin and DDT was determined by adult bioassays.The degree of resistance was determined by resistance ratio value(RR50>3)for larvae and by mortality for adult.The kdr alleles at codon 1534 of the VGSC gene were genotyped.The relationship between kdr genotypes and resistant phenotypes was analyzed by Chi-square test.Results:Out of five populations,assessed by larval bioassays,XI was susceptible to deltamethrin and permethrin;LT was susceptible to permethrin and beta-cypermethrin;and ST was susceptible to permithrin.FM and BP both were resistant to all of the three pyrethroids,and FM showed the highest degree of resistance,with RR50 values from 65.17 to 436.36.A total of 493 individuals from the larval bioassays were genotyped for kdr alleles.Five alleles were detected,including two wildtype alleles,TTC(F)(67.04%)and TTT(F)(0.41%),and three mutant alleles,TGC(C)(0.30%),TCC(S)(31.54%)and TTG(L)(0.71%).There was a clear correlation between mutant alleles(or F1534S)and resistant phenotypes(P<0.01).Conclusion:Two novel kdr mutant alleles F1534S and F1534L were detected in the pyrethroid resistant populations of Ae.albopictus in Haikou Hainan,China.For the first time,the mutant F1534S was associated with pyrethroid resistance in Ae.albopictus. | Huiying Chen Kaili Li Xiaohua Wang Xinyan Yang Yi Lin Fang Cai Wenbin Zhong Chunyan Lin Zhongling Lin Yajun Ma | 2016 | Infectious Diseases of Poverty2016，5，1： | 19 |
| 2 | Genome-Wide Expression Pattern Analyses of the Arabidopsis Leucine-Rich Repeat Receptor-Like Kinases显示文摘像受体的蛋白质 kinases (RLK ) 是在房间房间和房间环境通讯起关键作用的 transmembrane 蛋白质的一个大组。基于细胞外的领域结构, RLK 被分类进超过 21 个亚科,充满白氨酸的重复 RLK (LRR-RLKs ) 在象 Arabidopsis 和米饭那样的植物在之中属于最大的亚科。在 Arabidopsis,有近似 223LRR-RLKs,但是哪个中的仅仅大约 60 个机能上地迄今为止被描述了。为了系统地在调整调查 LRR-RLKs 的 theroles,种生长,开发,和压力改编,我们产生了 promoter::GUS 为在 Arabidopsis 的所有 223 LRR-RLK 基因的转基因的植物并且在各种各样的发展舞台分析了他们的详细表达式模式。Theresults 提供 forfunctionally 阐明的珍贵资源这个大、必要的发信号的蛋白质亚科。 | Yunzhe Wu Qingqing Xun Yi Guo Jinghua Zhang Kaili Cheng Tao Shi Kai He Suiwen Hou Xiaoping Gou Jia Li | 2016 | Molecular Plant2016，9，2： | 13 |
| 3 | A Facile Method to Improve the High Rate Capability of Co_(3)O_(4)Nanowire Array Electrodes显示文摘The capability of fast charge and fast discharge is highly desirable for the electrode materials used in supercapacitors and lithium ion batteries.In this article,we report a simple strategy to considerably improve the high rate capability of Co_(3)O_(4)nanowire array electrodes by uniformly loading Ag nanoparticles onto the surfaces of the Co_(3)O_(4)nanowires via the silver-mirror reaction.The highly electrically conductive silver nanoparticles function as a network for the facile transport of electrons between the current collectors(Ti substrates)and the Co_(3)O_(4)active materials.High capacity as well as remarkable rate capability has been achieved through this simple approach.Such novel Co_(3)O_(4)-Ag composite nanowire array electrodes have great potential for practical applications in pseudo-type supercapacitors as well as in lithium ion batteries. | Hua Cheng Zhou Guang Lu Jian Qiu Deng C.Y.Chung Kaili Zhang Yang Yang Li | 2010 | Nano Research2010，3，12： | 12 |
| 4 | Multiplexed Five-Color Molecular Imaging of Cancer Cells and Tumor Tissues with Carbon Nanotube Raman Tags in the Near-Infrared显示文摘Single-walled carbon nanotubes(SWNTs)with five different C13/C12 isotope compositions and well-separated Raman peaks have been synthesized and conjugated to five targeting ligands in order to impart molecular specificity.Multiplexed Raman imaging of live cells has been carried out by highly specific staining of cells with a five-color mixture of SWNTs.Ex vivo multiplexed Raman imaging of tumor samples uncovers a surprising up-regulation of epidermal growth factor receptor(EGFR)on LS174T colon cancer cells from cell culture to in vivo tumor growth.This is the first time five-color multiplexed molecular imaging has been performed in the near-infrared(NIR)region under a single laser excitation.Near zero interfering background of imaging is achieved due to the sharp Raman peaks unique to nanotubes over the low,smooth autofluorescence background of biological species. | Zhuang Liu Scott Tabakman Sarah Sherlock Xiaolin Li Zhuo Chen Kaili Jiang Shoushan Fan Hongjie Dai | 2010 | Nano Research2010，3，3： | 11 |
| 5 | Studies on Production of Biodiesel by Esterification of Fatty Acids by a Lipase Preparation from Candida sp. 99-125显示文摘A self-made lipase preparation from Candida sp. 99-125 was used for the production of biodiesel through enzymatic esterification of fatty acids. The crude lipase powder and fermentation broth were immobilized on a cheap fiber cloth carrier. The conditions of lipase-catalyzed esterification between long-chain fatty acids and methanol in a solvent system were investigated in detail, including the temperature, pH value, substrate concentration, solvent, absorbent agent, enzyme dosage and purity, immobilization method, the mode of addition of substrate. The results show that reaction temperature, pH of lipase micro-environment, substrate concentration, enzyme dosage and purity affect the esterification strongly. Several new methods and enzymatic procedures for improving the enzymatic reaction involving the process cost are also discussed, such as fossil diesel fuel as reaction solvent, immobilization method, multi-step gradient addition of methanol. The esterification degree of 92.8% was obtained with oleic acid and methanol under the optimal reaction condition after 12.5 h reaction time. The half-life of the immobilized lipase preparation from crude free lipase powder for esterification was 15 days. | DENG Li(邓利) NIE Kaili(聂开立) WANG Fang(王芳) TAN Tianwei(谭天伟) | 2005 | Chinese Journal of Chemical Engineering2005，13，4： | 8 |
| 6 | Highly conductive dodecaborate/MXene composites for high performance supercapacitors显示文摘With the increasingly prominent energy and environmental issues,the supercapacitors,as a highly efficient and clean energy conversion and storage devices,meet the requirements well.However,it is still a challenge to enhance the capacitance and energy density of supercapacitors.A novel and highly conductive dodecaborate/MXene composites have been designed for high performance supercapacitors.The surface charge property of MXene was modified by a simple ultrasonic treatment with ammonium ion,and the dodecaborate ion can be inserted into the inner surface of MXene by electrostatic adsorption.Due to the unique icosahedral cage conjugate structure formed by the B-B bond and the highly delocalized three-dimensionalπbond structure of the electrons,the negative charge is delocalied on the whole dodecaborate ion,which reduces the ability to bind to cations.Therefore,the cations can move easily,and the dodecaborate can act as a“lubricant”for ion diffusion between the MXene layers,which significantly improves the ion transfer rate of supercapacitors.The dodecaborate/MXene composites can achieve an extremely high specific capacitance of 366 F.g^-1 at a scan rate of 2 mV.s^-1,which is more than eight times higher than that of MXene(43 F1-)at the same scan rate.Our finding provides a novel route on the fabrication of the high performance supercapacitors. | Zhenxing Li Chang Ma Yangyang Wen Zhiting Wei Xiaofei Xing Junmei Chu Chengcheng Yu Kaili Wang Zhao-Kui Wang | 2020 | Nano Research2020，13，1： | 7 |
| 7 | THE RECURSIVE SOLUTION OF QUEUE LENGTH FOR Geo/G/1 QUEUE WITH N-POLICY显示文摘This paper considers a discrete-time queue with N-policy and LAS-DA(late arrival system with delayed access) discipline.By using renewal process theory and probability decomposition techniques,the authors derive the recursive expressions of the queue-length distributions at epochs n^-,n^+,and n.Furthermore,the authors obtain the stochastic decomposition of the queue length and the relations between the equilibrium distributions of the queue length at different epochs(n^-,n^+,n and departure epoch D_n). | Chuanyi LUO Yinghui TANG Wei LI Kaili XIANG | 2012 | Journal of Systems Science & Complexity2012，25，2： | 7 |
| 8 | Geochemistry and genesis of authigenic pyrite from gas hydrate accumulation system in the Qilian Mountain permafrost, Qinghai, northwest China显示文摘A type of authigenic pyrites that fully fill or semi-fill the rock fractures of drillholes with gas hydrate anomalies are found in the Qilian Mountain permafrost; this type of pyrite is known as 'fracture-filling' pyrite. The occurrence of 'fracture-filling' pyrite has a certain similarity with that of the hydrate found in this region, and the pyrite is generally concentrated in the lower part of the hydrate layer or the hydrate anomaly layer. The morphology, trace elements, rare earth elements, and sulfur isotope analyses of samples from drillhole DK-6 indicate that the 'fracture-filling' pyrites are dominated by cubic ones mainly aligned in a step-like fashion along the surfaces of rock fractures and are associated with a circular structure, lower Co/Ni and Sr/Ba, lower ?REE, higher LREE, significant Eu negative anomalies, and ? 34 SCDT positive bias. In terms of the pyrites' unique crystal morphology and geochemical characteristics and their relationship with the hydrate layers or abnormal layers, they are closely related with the accumulation system of the gas hydrate in the Qilian Mountain permafrost. As climate change is an important factor in affecting the stability of the gas hydrate, formation of fracture-filling pyrites is most likely closely related to the secondary change of the metastable gas hydrate under the regional climate warming. The distribution intensity of these pyrites indicates that when the gas hydrate stability zone(GHSZ) is narrowing, the hydrate decomposition at the bottom of the GHSZ is stronger than that at the top of the GHSZ, whereas the hydrate decomposition within the GHSZ is relatively weak. Thus, the zone between the shallowest and the deepest distribution of the fracture-filling pyrite recorded the largest possible original GHSZ. | WANG PingKang ZHU YouHai LU ZhenQuan HUANG Xia PANG ShouJi ZHANG Shuai JIANG ShaoQing LI QingHai YANG KaiLi LI Bing | 2014 | Science China Earth Sciences2014，57，9： | 6 |
| 9 | Efficient catalytic conversion of carbohydrates into 5-ethoxymethylfurfural over MIL-101-based sulfated porous coordination polymers显示文摘In this work, a series of MIL-101-SO3H(x) polymeric materials were prepared and further used for the first time as efficient heterogeneous catalysts for the conversion of fructose-based carbohydrates into 5-ethoxymethylfurfural(EMF) in a renewable mixed solvent system consisting of ethanol and tetrahydrofuran(THF). The influence of –SO3H content on the acidity as well as on the catalytic activity of the porous coordination polymers in EMF production was also studied. High EMF yields of 67.7% and 54.2% could be successively obtained from fructose and inulin in the presence of MIL-101-SO_3H(100) at 130 °C for 15 h.The catalyst could be reused for five times without significant loss of its activity and the recovery process was facile and simple. This work provides a new platform by application of porous coordination polymers(PCPs) for the production of the potential liquid fuel molecule EMF from biomass in a sustainable solvent system. | Xiaofang Liu Hu Li Hu Pan Heng Zhang Shan Huang Kaili Yang Wei Xue Song Yang | 2016 | Journal of Energy Chemistry2016，25，3： | 6 |
| 10 | Functional Metabolomics Reveals that Astragalus Polysaccharides Improve Lipids Metabolism through Microbial Metabolite 2-Hydroxybutyric Acid in Obese Mice显示文摘Polysaccharides are widely present in herbs with multiple activities,especially immunity regulation and metabolic benefits for metabolic disorders.However,the underlying mechanisms are not well under-stood.Functional metabolomics is increasingly used to investigate systemic effects on the host by iden-tifying metabolites with particular functions.This study explores the mechanisms underlying the metabolic benefits of Astragalus polysaccharides(APS)by adopting a functional metabolomics strategy.The effects of APS were determined in eight-week high-fat diet(HFD)-fed obese mice.Then,gas chromatography–time-of-flight mass spectrometry(GC–TOFMS)-based untargeted metabolomics was performed for an analysis of serum and liver tissues,and liquid chromatography–tandem mass spectrom-etry(LC–MS/MS)-based targeted metabolomics was performed.The potential functions of the metabo-lites were tested with in vitro and in vivo models of metabolic disorders.Our results first confirmed the metabolic benefits of APS in obese mice.Then,metabolomics analysis revealed that APS supplemen-tation reversed the HFD-induced metabolic changes,and identified 2-hydroxybutyric acid(2-HB)as a potential functional metabolite for APS activity that was significantly decreased by a HFD and reversed by APS.Further study indicated that 2-HB inhibited oleic acid(OA)-induced triglyceride(TG)accumula-tion.It was also found to stimulate the expression of proteins in lipid degradation in hepatocytes and TG lipolysis in 3T3-L1 cells.Moreover,it was found to reduce serum TG and regulate the proteins involved in lipid degradation in high-fat and high-sucrose(HFHS)-fed mice.In conclusion,our study demonstrates that the metabolic benefits of APS are at least partially due to 2-HB generation,which modulated lipid metabolism both in vitro and in vivo.Our results also highlight that functional metabolomics is practical for investigating the mechanism underlying the systemic benefits of plant polysaccharides. | Bingbing Li Ying Hong Yu Gu Shengjie Ye Kaili Hu Jian Yao Kan Ding Aihua Zhao Wei Jia Houkai Li | 2022 | Engineering2022，8，2： | 6 |
| 11 | Amoxicillin effects on functional microbial community and spread of antibiotic resistance genes in amoxicillin manufacture wastewater treatment system显示文摘This study aimed to reveal how amoxicillin(AMX) affected the microbial community and the spread mechanism of antibiotic resistance genes(ARGs) in the AMX manufacture wastewater treatment system. For this purpose, a 1.47 L expanded granular sludge bed(EGSB) reactor was designed and run for 241 days treating artificial AMX manufacture wastewater. 454 pyrosequencing was applied to analyze functional microorganisms in the system. The antibiotic genes OXA_(-1), OXA_(-2), OXA_(-10), TEM_(-1), CTX-M_(-1), class I integrons(intI1) and 16 SrRNA genes were also examined in sludge samples. The results showed that the genera Ignavibacterium, Phocoenobacter,Spirochaeta, Aminobacterium and Cloacibacillus contributed to the degradation of different organic compounds(such as various sugars and amines). And the relative quantification of eachβ-lactam resistance gene in the study was changed with the increasing of AMX concentration.Furthermore the vertical gene transfer was the main driver for the spread of ARGs rather than horizontal transfer pathways in the system. | Lingwei Meng Xiangkun Li Xinran Wang Kaili Ma Gaige Liu Jie Zhang | 2017 | Journal of Environmental Sciences2017，29，11： | 5 |
| 12 | Indium doped CsPbI3 films for inorganic perovskite solar cells with efficiency exceeding 17%显示文摘In recent years,all-inorganic perovskite materials have set off a research boom owing to features,such as good thermal stability,suitable bandgap,and fascinating optical properties.However,the power conversion efficiency(PCE)and the ambient stability of all-inorganic perovskite solar cells still remain a challenge.Herein,we investigate the effect of the addition of InI3 into CsPbI3 film on the corresponding device.InI3 incorporation could retard the crystallization process and control the growth rate of CsPbI3 polycrystalline films,yielding a high quality film with large grains and few voids.The increment in electrostatic potential and the reduction of carrier recombination enabled the open-circuit voltage of fabricated perovskite solar cell to be increased from 0.89 to 0.99 V.The champion device delivered a power conversion efficiency of 17.09%,which is higher than 14.36%for the reference device.And the InI3-included solar cell without any encapsulation retained 77%of its original efficiency after 860 h aging at room temperature in N2 condition. | Xiaomei Li Kaili Wang Femi Lgbari Chong Dong Wenfan Yang Chang Ma Heng Ma Zhao-Kui Wang Liang-Sheng Liao | 2020 | Nano Research2020，13，8： | 4 |
| 13 | Implantable nerve guidance conduits:Material combinations,multi-functional strategies and advanced engineering innovations显示文摘Nerve guidance conduits(NGCs)have attracted much attention due to their great necessity and applicability in clinical use for the peripheral nerve repair.Great efforts in recent years have been devoted to the development of high-performance NGCs using various materials and strategies.The present review provides a comprehensive overview of progress in the material innovation,structural design,advanced engineering technologies and multi functionalization of state-of-the-art nerve guidance conduits NGCs.Abundant advanced engineering technologies including extrusion-based system,laser-based system,and novel textile forming techniques in terms of weaving,knitting,braiding,and electrospinning techniques were also analyzed in detail.Findings arising from this review indicate that the structural mimetic NGCs combined with natural and synthetic materials using advanced manufacturing technologies can make full use of their complementary advantages,acquiring better biomechanical properties,chemical stability and biocompatibility.Finally,the existing challenges and future opportunities of NGCs were put forward aiming for further research and applications of NGCs. | Yixin Yan Ruotong Yao Jingyuan Zhao Kaili Chen Lirong Duan Tian Wang Shujun Zhang Jinping Guan Zhaozhu Zheng Xiaoqin Wang Zekun Liu Yi Li Gang Li | 2022 | Bioactive Materials2022，7，5： | 4 |
| 14 | Ecological niches and blood sources of sand fly in an endemic focus of visceral leishmaniasis in Jiuzhaigou,Sichuan,China显示文摘Background:Sand fly Phlebotomus chinensis is a principle vector for the visceral leishmaniasis(VL)in China with a wide geographic distribution.Jiuzhaigou,Sichuan is a mountain type endemic area of VL in China.Long term effective control efforts in the region have successfully reduced VL transmission.To assess the current status of the sand flies and their ecological aspects in the region,a survey was conducted in the summer of 2014 and 2015.Methods:Sand fly specimens were collected by light traps in a village and blood sources were identified by PCR and sequencing of the mitochondrial cytochrome b gene.Results:In a rock cave,65.2%–79.8%of collected sand flies were male.On a rabbit farm,92.9%–98.8%of specimens were female.In pig pens,61.1%of specimens were female.Some females had visible blood residues.The feeding rate was 49.4%from the pig pens,12.3%from the cave,and only 1.7%from the rabbit farm.Pig,rabbit,chicken,dog,and human blood were detected in the fed specimens.Swine blood,present in all tested samples,was a preferred blood source,while chicken and dog blood were present in a third of the samples.Conclusions:In Jiuzhaigou County,Sichuan Province of China,the considerable sandfly density and the peridomestic feeding behavior all increases the risk of VL transmission,and insecticide spraying in animal sheds could be exploited to reduce sand fly populations in human surroundings. | Huiying Chen Kaili Li Hua Shi Yong Zhang Yu Ha Yan Wang Jinjin Jiang Yubin Wang Zhenzhou Yang Jiannong Xu Yajun Ma | 2016 | Infectious Diseases of Poverty2016，5，1： | 3 |
| 15 | Integration of data-intensive,machine learning and robotic experimental approaches for accelerated discovery of catalysts in renewable energy-related reactions显示文摘Technological advancements in recent decades have greatly transformed the field of material chemistry.Juxtaposing the accentuating energy demand with the pollution associated,urgent measures are required to ensure energy maximization,while reducing the extended experimental time cycle involved in energy production.In lieu of this,the prominence of catalysts in chemical reactions,particularly energy related reactions cannot be undermined,and thus it is critical to discover and design catalyst,towards the optimization of chemical processes and generation of sustainable energy.Most recently,artificial intelligence(AI)has been incorporated into several fields,particularly in advancing catalytic processes.The integration of intensive data set,machine learning models and robotics,provides a very powerful tool in modifying material synthesis and optimization by generating multifarious dataset amenable with machine learning techniques.The employment of robots automates the process of dataset and machine learning models integration in screening intermetallic surfaces of catalyst,with extreme accuracy and swiftness comparable to a number of human researchers.Although,the utilization of robots in catalyst discovery is still in its infancy,in this review we summarize current sway of artificial intelligence in catalyst discovery,briefly describe the application of databases,machine learning models and robots in this field,with emphasis on the consolidation of these monomeric units into a tripartite flow process.We point out current trends of machine learning and hybrid models of first principle calculations(DFT)for generating dataset,which is integrable into autonomous flow process of catalyst discovery.Also,we discuss catalyst discovery for renewable energy related reactions using this tripartite flow process with predetermined descriptors. | Oyawale Adetunji Moses Wei Chen Mukhtar Lawan Adam Zhuo Wang Kaili Liu Junming Shao Zhengsheng Li Wentao Li Chensu Wang Haitao Zhao Cheng Heng Pang Zongyou Yin Xuefeng Yu | 2021 | Materials Reports(Energy)2021，1，3： | 3 |
| 16 | Machine learning accelerated calculation and design of electrocatalysts for CO_(2) reduction显示文摘In the past decades,machine learning(ML)has impacted the field of electrocatalysis.Modern researchers have begun to take advantage of ML‐based data‐driven techniques to overcome the computational and experimental limitations to accelerate rational catalyst design.Hence,significant efforts have been made to perform ML to accelerate calculation and aid electrocatalyst design for CO_(2) reduction.This review discusses recent applications of ML to discover,design,and optimize novel electrocatalysts.First,insights into ML aided in accelerating calculation are presented.Then,ML aided in the rational design of the electrocatalyst is introduced,including establishing a data set/data source selection and validation of descriptor selection of ML algorithms validation and predictions of the model.Finally,the opportunities and future challenges are summarized for the future design of electrocatalyst for CO_(2) reduction with the assistance of ML. | Zhehao Sun Hang Yin Kaili Liu Shuwen Cheng Gang Kevin Li Sibudjing Kawi Haitao Zhao Guohua Jia Zongyou Yin | 2022 | SmartMat2022，3，1： | 2 |
| 17 | High temperature performance of coaxial h-BN/CNT wires above 1,000 ℃:Thermionic electron emission and thermally activated conductivity显示文摘The development of wires and cables that can tolerate extremely high temperatures will be very important for probing extreme environments, such as in solar exploration, fire disasters, high-temperature materials processing, aeronautics and astronautics. In this paper, a lightweight high-temperature coaxial h-boron nitride (BN)/carbon nanotube (CNT) wire is synthesized by the chemical vapor deposition (CVD) epitaxial growth of h-BN on CNT yarn. The epitaxially grown h-BN acts as both an insulating material and a jacket that protects against oxidation. It has been shown that the thermionic electron emission (1,200 K) and thermally activated conductivity (1,000 K) are two principal mechanisms for insulation failure of h-BN at high temperatures. The thermionic emission of h-BN can provide the work function of h-BN, which ranges from 4.22 to 4.61 eV in the temperature range of 1,306-1,787 K. The change in the resistivity of h-BN with temperature follows the ohmic conduction model of an insulator, and it can provide the “electron activation energy”(the energy from the Fermi level to the conduction band of h-BN), which ranges from 2.79 to 3.08 eV, corresponding to a band gap for h-BN ranging from 5.6 to 6.2 eV. However, since the leakage current is very small, both phenomena have no obvious influence on the signal transmission at the working temperature. This lightweight coaxial h-BN/CNT wire can tolerate 1,200 ℃ in air and can transmit electrical signals as normal. It is hoped that this lightweight high-temperature wire will open up new possibilities for a wide range of applications in extreme high-temperature conditions. | Xinhe Yang Peng Liu Duanliang Zhou Feng Gao Xinhe Wang Shiwei Lv Zi Yuan Xiang Jin Wei Zhao Haoming Wei Lina Zhang Jiandong Gao Qunqing Li Shoushan Fan Kaili Jiang | 2019 | Nano Research2019，12，8： | 2 |
| 18 | Resveratrol suppresses P-selectin, PSGL-1, and VWF through SIRT1 signaling pathway显示文摘 | Zhenkai Lou Kaili Du Tingting Wang Xueling Zhao Xingguo Li Bing Wang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，9： | 2 |
| 19 | Multicomponent transition metal phosphide for oxygen evolution显示文摘Transition metal phosphides(TMPs)have exhibited decent performance in an oxygen evolution reaction(OER),which is a kinetic bottleneck in many energy storages and conversion systems.Most reported catalysts are composed of three or fewer metallic components.The inherent complexity of multicomponent TMPs with more than four metallic components hinders their investigation in rationally designing the structure and,more importantly,comprehending the component-activity correlation.Through hydrothermal growth and subsequent phosphor-ization,we reported a facile strategy for combining TMPs with tunable elemental compositions(Ni,Fe,Mn,Co,Cu)on a two-dimensional ti-tanium carbide(MXene)flake.The obtained TMPs/MXene hybrid nanostructures demonstrate homogeneously distributed elements.They ex-hibit high electrical conductivity and strong interfacial interaction,resulting in an accelerated reaction kinetics and long-term stability.The res-ults of different component catalysts’OER performance show that NiFeMnCoP/MXene is the most active catalyst,with a low overpotential of 240 mV at 10 mA·cm−2,a small Tafel slope of 41.43 mV·dec−1,and a robust long-term electrochemical stability.According to the electrocata-lytic mechanism investigation,the enhanced NiFeMnCoP/MXene OER performance is due to the strong synergistic effect of the multi-ele-mental composition.Our work,therefore,provides a scalable synthesis route for multi-elemental TMPs and a valuable guideline for efficient MXene-supported catalysts design. | Lihua Liu Ning Li Jingrui Han Kaili Yao Hongyan Liang | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，3： | 1 |
| 20 | A virus-derived siRNA activates plant immunity by interfering with ROS scavenging显示文摘Virus-derived small interference RNAs(vsiRNAs)not only suppress virus infection in plants via induction of RNA silencing but also enhance virus infection by regulating host defensive gene expression.However,the underlying mechanisms that control vsiRNA-mediated host immunity or susceptibility remain largely unknown.In this study,we generated several transgenic wheat lines using four artificial microRNA expression vectors carrying vsiRNAs from Wheat yellow mosaic virus(WYMV)RNA1.Laboratory and field tests showed that two transgenic wheat lines expressing amiRNAI were highly resistant to WYMV infection.Further analyses showed that vsiRNAI could modulate the expression of a wheat thioredoxin-like gene(TaAAEDI),which encodes a negative regulator of reactive oxygen species(ROS)production in the chloroplast.The function of TaAAEDI in ROS scavenging could be suppressed by vsiRNAI in a dose-dependent manner.Furthermore,transgenic expression of amiRNAI in wheat resulted in broad-spectrum disease resistance to Chinese wheat mosaic virus,Barley stripe mosaic virus,and Puccinia striiformis f.sp.tritici infection,suggesting that vsiRNAI is involved in wheat immunity via ROS signaling.Collectively,these findings reveal a previously unidentified mechanism underlying the arms race between viruses and plants. | Peng Liu Xiaoxiang Zhang Fan Zhang Miaoze Xu Zhuangxin Ye Ke Wang Shuang Liu Xiaolei Han Ye Cheng Kaili Zhong Tianye Zhang Linzhi Li Youzhi Ma Ming Chen Jianping Chen Jian Yang | 2021 | Molecular Plant2021，14，7： | 1 |
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