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| 1 | Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis显示文摘AIM:To test the hypothesis that liver cirrhosis is associated with mobilization of hematopoietic progenitor cells. METHODS:Peripheral blood samples from 72 patients with liver cirrhosis of varying etiology were analyzed by flow cytometry.Identified progenitor cell subsets were immunoselected and used for functional assays in vitro. Plasma levels of stromal cell-derived factor-1(SDF-1) were measured using an enzyme linked immunosorbent assay.RESULTS:Progenitor cells with a CD133 + /CD45 + CD14 + phenotype were observed in 61%of th patients.Between 1%and 26%of the peripheral bloo mononuclear cells(MNCs)displayed this phenotype Furthermore,a distinct population of c-kit + progenito cells(between 1%and 38%of the MNCs)could b detected in 91%of the patients.Additionally,18% of the patients showed a population of progenito cells(between 1%and 68%of the MNCs)that wa characterized by expression of breast cancer resistanc protein-1.Further phenotypic analysis disclosed tha the circulating precursors expressed CXC chemokin receptor 4,the receptor for SDF-1.In line with thi finding,elevated plasma levels of SDF-1 were presen in all patients and were found to correlate with th number of mobilized CD133 + progenitor cells. | Ursula M Gehling Marc Willems Kathleen Schlagner Ralf A Benndorf Maura Dandri Jrg Petersen Martina Sterneck Joerg-Matthias Pollok Dieter K Hossfeld Xavier Rogiers | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 2 | Prediction of delayed graft function using different scoring algorithms: A single-center experience显示文摘AIM To compare the performance of 3 published delayed graftfunction(DGF) calculators that compute the theoretical risk of DGF for each patient.METHODS This single-center,retrospective study included 247 consecutive kidney transplants from a deceased donor.These kidney transplantations were performed at our institution between January 2003 and December 2012.We compared the occurrence of observed DGF in our cohort with the predicted DGF according to three different published calculators. The accuracy of the calculators was evaluated by means of the c-index(receiver operating characteristic curve).RESULTS DGF occurred in 15.3% of the transplants under study.The c index of the Irish calculator provided an area under the curve(AUC) of 0.69 indicating an acceptable level of prediction,in contrast to the poor performance of the Jeldres nomogram(AUC = 0.54) and the Chapal nomogram(AUC = 0.51). With the Irish algorithm the predicted DGF risk and the observed DGF probabilities were close. The mean calculated DGF risk was significantly different between DGF-positive and DGF-negative subjects(P < 0.0001). However,at the level of the individual patient the calculated risk of DGF overlapped very widely with ranges from 10% to 51% for recipients with DGF and from 4% to 56% for those without DGF.The sensitivity,specificity and positive predictive value of a calculated DGF risk ≥ 30% with the Irish nomogram were 32%,91% and 38%. CONCLUSION Predictive models for DGF after kidney transplantation are performant in the population in which they were derived,but less so in external validations. | Magda Michalak Kristien Wouters Erik Fransen Rachel Hellemans Amaryllis H Van Craenenbroeck Marie M Couttenye Bart Bracke Dirk K Ysebaert Vera Hartman Kathleen De Greef Thiery Chapelle Geert Roeyen Gerda Van Beeumen Marie-Paule Emonds Daniel Abramowicz Jean-Louis Bosmans | 2017 | World Journal of Transplantation2017，7，5： | 3 |
| 3 | Performance monitoring and stop signal inhibition in abstinent patients with cocaine dependence显示文摘 | Chiang-shan Ray L Verica M Kathleen K | 2006 | Drug Alcohol Depend2006，，85： | 1 |
| 4 | Theoretical and experimental considerations for interpretationof amide I bands in tissue 显示文摘 | KATHLEEN M G LSAN T MARZENA Z K | 2011 | Vibrational Spectroscopy2011，53，1： | 1 |
| 5 | The Use of Tympanometry and Pneumatic Otoscopy for Predicting Middle Ear Disease显示文摘 | Paula K Kathleen M Joseph J | 2005 | Am J Audiol2005，14，6： | 1 |
| 6 | Long-term safety and once-daily niacin/lovastatin formulation for patients with dyslipidemia 显示文摘 | Moti L K Mark E M Kathleen B | 2002 | Am J Cardiol2002，89，6： | 1 |
| 7 | Cost-effectiveness of rosuvastatinin comparison withgeneric atorvastatin and simvastatin in a Swedish popu-lationat high risk of cardiovascular events显示文摘 | Sanjay K Gandhi Marie M Jensen Kathleen M Fox? etal | 2012 | Clinico-Economics and Outcomes Research ?2012 ?4:1-112012，4，： | 1 |
| 8 | Antifungal activity of redox-active benzaldehydes that target cellular antioxidation显示文摘 | Jong H K Kathleen L C Noreen M | 2011 | Ann Clin Microbiol Antimicrob2011，10，： | 1 |
| 9 | 17 β-estradiol acts directly on the clonal osteoblastic cell line UMR 106显示文摘 | GRAY T K TIMOTHY C F KATHLEEN M G | 1987 | Proc Natl Acad Sci1987，84，17： | 1 |
| 10 | Introduction of a composite parameter to the pharmacokinetics of venlafaxine and its active o - desmethyl metabolite显示文摘 | Karen J K Kathleen M Richard L R | 1992 | J Clin Pharmaco1992，32，8： | 1 |
| 11 | p120-Catenin regulates elathrin-dependent endoeytosis of VE-cadherin显示文摘 | Xiao K Y Garner J Kathleen M | 2005 | J Mol Biol Cell2005，16，11： | 1 |
| 12 | Educational prepa- ration for clinical nursing: The satisfaction of students and new graduates from two Australian universities显示文摘 | Kathleen M Patricial K Glenda P | 2014 | Nurse Edueation Today2014，34，4： | 1 |
| 13 | An unusual modern silica-carbornate sinter from Pavlova spring,Ngatamariki,New Zealand显示文摘 | Kathleen A Campbell Rodgers K A Brotheridge Jane M A | 2002 | Sedimentology2002，49，4： | 1 |
| 14 | Undergroundmine refuge chamber expectations training : program development andevaluation显示文摘 | Katherine A M Catherine Y K W Kathleen M K | 2011 | Safety Science2011，49，3： | 1 |
| 15 | Fathead minnow vitellogenin:complementary DNA sequence and messenger RNA and protein expression after 17 β-estradiol treatment显示文摘 | Joseph J K Michael D K Kathleen M J | 2000 | Environmental Toxicology and Chemistry2000，19，4： | 1 |
| 16 | H1N1 2009 influenza virus infection during pregnancy in the USA显示文摘 | Denise J Jamieson Margaret A Honein Sonja A Rasmussen Jennifer L Williams David L Swerdlow Matthew S Biggerstaff Stephen Lindstrom Janice K Louie Cara M Christ Susan R Bohm Vincent P Fonseca Kathleen A Ritger Daniel J Kuhles Paula Eggers Hollianne Bruce H | 2009 | The Lancet2009，，9688： | 1 |
| 17 | The Taxus drug- eluting stent: A new paradigm in controlled drug delivery显示文摘 | Kalpana R K James J B Kathleen M M | 2006 | Advanced Drug Delivery Reviews2006，58，3： | 1 |
| 18 | Chambers:A review of the concept of culture in holistic nursing literature 显示文摘 | Donelle M B Kathleen K C Kathryn B | 2000 | Journal of Holistic nursing2000，18，3： | 1 |
| 19 | Performance monito- ring and stop signal inhibition in abstinent patients with cocaine de- pendence 显示文摘 | Chiang-shan RL Verica M Kathleen K | 2006 | Drug Alcohol Depend2006，85，3： | 1 |
| 20 | Microbial cycling of DMSP and DMS in coastal and oligotrophie seawa- ter显示文摘 | KATHLEEN M LEDYARD K M JOHN W H DACEY J W H | 1996 | Limnology and Oeeanography1996，41，1： | 1 |
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