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| 1 | Carbon isotopic composition of Early Triassic marine carbonates, Eastern Sichuan Basin, China显示文摘As the interval following the biggest Phanerozoic mass extinction at the end of Permian, the Early Triassic is characterized by an immature, poorly functioned ecosystem.The effects of these extreme environmental conditions can be mirrored by the changes in the δ13C record of marine carbonates.However, the details about the carbon isotopic composition and evolution of the Early Triassic seawater remain poorly understood.A dataset of new δ13C and δ18O values as well as selected major and trace element data (including concentrations of CaO, MgO, Mn, and Sr) was obtained from 113 marine carbonate samples collected in Eastern Sichuan Basin.The isotopic and elemental data are used to evaluate effects of thermochemical sulfate reduction on δ13C.The δ13C values of a few samples affected by thermochemical sulfate reduction were corrected.By combining carbonate δ13C results in our investigated sections, we constructed a composite curve of the Lower Triassic.The results reveal a δ13C anomaly of carbonate rocks throughout the Early Triassic, accompanied by some rapid jumps and falls, such as those from approximately -2‰ to the extremely high value of 8‰ within a period of about 5 Ma.The Early Triassic δ13C profile derived from Eastern Sichuan Basin shows a close correspondence with Guandao section in Guizhou Province, whereas it yields an excursion pattern differing from Chaohu section in Anhui Province of the Lower Yangtze region (with the δ13C value from the minimum around -6‰ to the maximum near 4‰).The higher δ13C values and the positive carbon isotope excursions in the Lower Triassic from Eastern Sichuan Basin were most likely a consequence of the principal environmental change that may include: (1) the barren land surface due to the absence of vegetation, (2) the loss of diverse marine invertebrate groups and marine carbonates, (3) the thriving of bacteria, algae and methanogenus in ocean ecosystems, and (4) the local effect of the repositories of isotopically light carbon occurred in the form of methane hydrates.This process ended at the Early-Middle Triassic boundary, which indicates that the biotic recovery started at the end of the Lower Triassic.The terrestrial vegetation and marine invertebrates, as the regulators for carbon cycle, are irreplaceable and demand strong protections. | HUANG SiJing HUANG KeKe LÜ Jie LAN YeFang | 2012 | Science China Earth Sciences2012，55，12： | 18 |
| 2 | Two RING-Finger Ubiquitin E3 Ligases Regulate the Degradation of SPX4, An Internal Phosphate Sensor, for Phosphate Homeostasis and Signaling in Rice显示文摘SPX-domain-containing proteins (SPXs) play an important role in inorganic phosphate (Pi) sensing,signaling,and transport in eukaryotes.In plants,SPXs are known to integrate cellular Pi status and negatively regulate the activity of Pi central regulators,the PHOSPATE STARVATION RESPONSE proteins (PHRs).The stability of SPXs,such as SPX4,is reduced under Pi-deficient conditions.However,the mechanisms by which SPXs are degraded remain unclear.In this study,using a yeast-twhybrid screen we iden.tified two RING-finger ubiquitin E3 ligases regulating SPX4 degradation,designated SDEL1 and SDEL2,which were post-transcriptionally induced by Pi starvation.We found that both SDELs were located in the nucleus and cytoplasm,had ubiquitin E3 ligase activity,and directly ubiquitinated the K^213 and K^299 lysine residues in SPX4 to regulate its stability.Furthermore,we found that PHR2,a Pi central regulator in rice,could compete with SDELs by interacting with SPX4 under Pi-sufficient conditions,which protected SPX4 from ubiquitination and degradation.Consistent with the biochemical function of SDEL1 and SDEL2,overexpression of SDEL1 or SDEL2 resulted in Pi overaccumulation and induced Pi-starvation signaling even under Pi-sufficient conditions.Conversely,their loss-of-function mutants displayed decreased Pi accumulation and reduced Pi-starvation signaling.Collectively,our study revealed that SDEL1 and SDEL2 facilitate the degradation of SPX4 to modulate PHR2 activity and regulate Pi homeostasis and Pi signaling in response to external Pi availability in rice. | Wenyuan Ruan Meina Guo Xueqing Wang Zhenhui Guo Zhuang Xu Lei Xu Hongyu Zhao Haiji Sun Chengqi Yan Keke Yi | 2019 | Molecular Plant2019，12，8： | 14 |
| 3 | Dietary supplementation with Clostridium butyricum improves growth performance of broilers by regulating intestinal microbiota and mucosal epithelial cells显示文摘Clostridium butyricum has been widely considered an antibiotic substitute in recent years.It can promote growth performance,improve the immune response and enhance the intestinal barrier function of the host.In the present study,1-d-old Arbor Acres(AA)broilers were fed C.butyricum(1×109 cfu/kg)for 28 d.The transcriptomic characteristics of epithelial cells of the cecal mucosa were determined by RNA-sequence,and the cecal microbiota composition was explored by 16 S ribosomal RNA gene sequencing.The changes in the intestinal mucosa of broilers were then analyzed by tissue staining.Gene Ontology(GO)annotations identified substance transport and processes and pathways that might participate in intestinal development and cell viability.Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis revealed that the differentially expressed genes are involved in numerous pathways related to amino acid and vitamin metabolism and antioxidant and defensive functions,among others.The relative expression of some genes associated with intestinal barrier function(claudins 2,15,19,and 23,tight junction proteins 1,2,and 3 and mucin 1)was significantly increased in the treatment group(P<0.05 or P<0.01).Moreover,the proportion of Firmicutes was higher in the C.butyricum-treated group,whereas the proportion of Proteobacteria was higher in the control group.At the genus level,the relative abundances of Butyricicoccus and Lactobacillus,among other bacteria,were increased after C.butyricum supplementation.The tissue staining analysis showed that the cecal mucosa of broilers was significantly ameliorated after the addition of C.butyricum(P<0.05 or P<0.01).These results showed that dietary supplementation with C.butyricum can enhance the antioxidant capacity,mucosal barrier function,and stabilize the cecal microbiota,resulting in improving the growth performance. | Laipeng Xu Xiangli Sun Xianhua Wan Keke Li Fuchun Jian Wenting Li Ruirui Jiang Ruili Han Hong Li Xiangtao Kang Yanbin Wang | 2021 | Animal Nutrition2021，，4： | 12 |
| 4 | Low-Dimensional Halide Perovskites and Their Advanced Optoelectronic Applications显示文摘Metal halide perovskites are crystalline materials originally developed out of scientific curiosity. They have shown great potential as active materials in optoelectronic applications. In the last 6 years, their certified photovoltaic efficiencies have reached 22.1%. Compared to bulk halide perovskites, low-dimensional ones exhibited novel physical properties. The photoluminescence quantum yields of perovskite quantum dots are close to 100%. The external quantum efficiencies and current efficiencies of perovskite quantum dot light-emitting diodes have reached 8% and 43 cd A^(-1),respectively, and their nanowire lasers show ultralow-threshold room-temperature lasing with emission tunability and ease of synthesis. Perovskite nanowire photodetectors reached a responsivity of 10 A W^(-1)and a specific normalized detectivity of the order of 10^(12 )Jones. Different from most reported reviews focusing on photovoltaic applications, we summarize the rapid progress in the study of low-dimensional perovskite materials, as well as their promising applications in optoelectronic devices. In particular, we review the wide tunability of fabrication methods and the state-of-the-art research outputs of low-dimensional perovskite optoelectronic devices. Finally, the anticipated challenges and potential for this exciting research are proposed. | Jian Zhang Xiaokun Yang Hui Deng Keke Qiao Umar Farooq Muhammad Ishaq Fei Yi Huan Liu Jiang Tang Haisheng Song | 2017 | Nano-Micro Letters2017，9，3： | 10 |
| 5 | Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma显示文摘Background:Resistance to ferroptosis,a regulated cell death caused by irondependent excessive accumulation of lipid peroxides,has recently been linked to lung adenocarcinoma(LUAD).Intracellular antioxidant systems are required for protection against ferroptosis.The purpose of the present studywas to investigate whether and how extracellular system desensitizes LUAD cells to ferroptosis.Methods:Established human lung fibroblasts MRC-5,WI38,and human LUAD H1650,PC9,H1975,H358,A549,and H1299 cell lines,tumor and matched normal adjacent tissues of LUAD,and plasma from healthy individuals and LUAD patients were used in this study.Immunohistochemistry and immunoblotting were used to analyze protein expression,and quantitative reverse transcription-PCR was used to analyze mRNA expression.Cell viability,cell death,and the lipid reactive oxygen species generationwere measured to evaluate the responses to ferroptosis.Exosomes were observed using transmission electron microscope.The localization of arachidonic acid(AA)was detected using click chemistry labeling followed by confocal microscopy.Interactions between RNAs and proteins were detected using RNA pull-down,RNA immunoprecipitation and photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation methods.Proteomic analysis was used to investigate RNA-regulated proteins,and metabolomic analysis was performed to analyze metabolites.Cellderived xenograft,patient-derived xenograft,cell-implanted intrapulmonary LUAD mouse models and plasma/tissue specimens from LUAD patients were used to validate the molecular mechanism.Results:Plasma exosome from LUAD patients specifically reduced lipid peroxidation and desensitized LUAD cells to ferroptosis.A potential explanation is that exosomal circRNA_101093(cir93)maintained an elevation in intracellular cir93 in LUAD to modulate AA,a poly-unsaturated fatty acid critical for ferroptosisassociated increased peroxidation in the plasma membrane.Mechanistically,cir93 interacted with and increased fatty acid-binding protein 3(FABP3),which transported AA and facilitated its reaction with taurine.Thus,global AA was reduced,whereas N-arachidonoyl taurine(NAT,the product of AA and taurine)was induced.Notably,the role of NAT in suppressing AA incorporation into the plasma membrane was also revealed.In pre-clinical in vivo models,reducing exosome improved ferroptosis-based treatment.Conclusion:Exosome and cir93 are essential for desensitizing LUAD cells to ferroptosis,and blocking exosome may be helpful for future LUAD treatment. | Xiao Zhang Yunhua Xu Lifang Ma Keke Yu Yongjie Niu Xin Xu Yi Shi Susu Guo Xiangfei Xue Yikun Wang Shiyu Qiu Jiangtao Cui Hong Wang Xiaoting Tian Yayou Miao Fanyu Meng Yongxia Qiao Yongchun Yu Jiayi Wang | 2022 | Cancer Communications2022，42，4： | 10 |
| 6 | Superplastic Solid-Phase Welding of 40 Cr-T10A Steel显示文摘The microstructure of 40Cr and T10A steel sample and its surface to be welded is ultra-fined through salt-bath cyclic quenching and high frequency hardening, then the surface is cleaned. Under non-vacuum and no shielded gas, the welding parameter of isothermal superplastic solidphase welding and the effect of surface microstructure prior to pressure welding on the quality of joint are studied. At the temperature of 730~750°C and at initial strain rate of (2~4) × 10-4 s-1,the strength of the joint is up to or close to that of 40Cr base metal in 3~5 min pressure welding. | Keke ZHANG Yunlin YANG Changsheng WANG Hongke LI Jin XUE | 2001 | Journal of Materials Science & Technology2001，17，1： | 10 |
| 7 | A large carbon pool in lake sediments over the arid/semiarid region, NW China显示文摘Carbon burial in lake sediments is an important component of the global carbon cycle. However, little is known about the magnitude of carbon sequestered in lake sediments over the arid/semiarid region of China(ASAC).In this study, we estimate both organic and inorganic carbon burial since *AD 1800 based on nine lakes in ASAC,and discuss the most plausible factors controlling carbon burial. Our estimates show that the annual organic carbon burial rate(OCBR) ranges from 5.3 to 129.8 g cm-2year-1(weighted mean of 49.9 g cm-2year-1), leading to a standing stock of 1.1–24.0 kg cm-2(weighted mean of 8.6 kg cm-2)and a regional sum of *108 Tg organic carbon sequestered since *AD 1800. The annual inorganic carbon burial rate(ICBR) ranges from 11.4 to 124.0 g cm-2year-1(weighted mean of 48.3 g cm-2year-1), which is slightly lower than OCBR. The inorganic carbon standing stock ranges from2.4 to 26.0 kg cm-2(weighted mean of 8.1 kg cm-2),resulting in a sum of *101 Tg regional inorganic carbon burial since *AD 1800, which is slightly lower than the organic carbon sequestration. OCBR in ASAC shows a continuously increasing trend since *AD 1950, which is possibly due to the high autochthonous and allochthonous primary production and subsequently high sedimentation rate in the lakes. This increasing carbon burial is possibly related to both climatic changes and enhanced anthropogenic activities, such as land use change, deforestation, and eutrophication in the lake. Furthermore, OCBR and ICBR are expected to continuously increase under the scenario of increasing precipitation and runoff and enhanced anthropogenic activities.The results of this research show that the buried carbon in lake sediments of the ASAC region constitutes a significant and large carbon pool, which should be considered and integrated into the global carbon cycle. | Jianghu Lan Hai Xu Bin Liu Enguo Sheng Jiangtao Zhao Keke Yu | 2015 | Chinese Journal Of Geochemistry2015，34，3： | 10 |
| 8 | Modifi cation of wheat bran insoluble and soluble dietary fibers with snail enzyme显示文摘Insoluble dietary fiber(IDF)and soluble dietary fiber(SDF)extracted from wheat bran were modifi ed by snail enzyme and their physicochemical properties(water retention capacity and oil retention capacity),functional properties(cholesterol adsorption capacity,glucose adsorption capacity and antioxidant activity)and structural characterizations were evaluated.The results showed that snail enzyme modification led to the significant increase in oil retention capacity of IDF,glucose adsorption capacity and cholesterol adsorption capacity of IDF and SDF.Enzymatic modification also markedly improved the DPPH radical scavenging capacity and reducing power of IDF and SDF.Meanwhile,scanning electron microscopy(SEM)analysis indicated the microstructures of IDF and SDF powders were signifi cantly changed.Fourier transfer-infrared spectrometry(FT-IR)showed that snail enzyme modifi cation could degrade the part of cellulose and hemicellulose of IDF and SDF.All these improved physicochemical and functional properties of IDF and SDF might depend on their structural changes.It suggested that snail enzyme modifi cation could effectively improve physicochemical and functional properties of IDF and SDF from wheat bran. | Xin Liu Keke Suo Pei Wang Xue Li Limin Hao Jiaqing Zhu Juanjuan Yi Qiaozhen Kang Jinyong Huang Jike Lu | 2021 | Food Science and Human Wellness2021，10，3： | 10 |
| 9 | The relationship between dolomite textures and their formation temperature: a case study from the Permian-Triassic of the Sichuan Basin and the Lower Paleozoic of the Tarim Basin显示文摘Study of dolomite texture can contribute to understanding the process of dolomitization. This research reports textures and homogenization temperatures of dolomites from the Permian–Triassic strata in the Sichuan Basin and the Lower Paleozoic strata in the Tarim Basin, which provided insights into relationships between dolomite textures and their formation temperatures. Our results are summarized as follows: 1) dolomites with well-preserved texture indicate low dolomitization temperature. However, in certain diagenetic environments, the hydrothermal dolomitization may completely or partially preserve the original texture of dolomites. 2) The formation temperatures of non-planar dolomites are always higher than those of planar dolomites. 3) The formation temperatures of dolomite cements are generally higher than those of replacive dolomites. 4) Although the formation temperatures of saddle dolomite cements have a wide range, they show higher values than those of the planar subhedral to euhedral dolomite cements. Thus, saddle dolomites could generally be an indicator of high precipitation temperature. 5) The fluid Mg/Ca ratio is another element controlling dolomite morphology. Micritic dolomites, which precipitate from hypersaline fluids with a high Mg/Ca ratio in a subaerial environment could also have features of non-planar anhedral crystal shape because of rapid nucleation and crystallization during dolomitization. | Huang Sijing Huang Keke Lü Jie Lan Yefang | 2014 | Petroleum Science2014，11，1： | 9 |
| 10 | Non-injection gram-scale synthesis of cesium lead halide perovskite quantum dots with controllable size and composition显示文摘金属卤化物 perovskites 是为太阳的收获和轻射出应用被认为候选人好的新奇 optoelectronic 材料。在这研究,我们为综合开发一条可再现、便宜的途径 highquality 铯铅卤化物 perovskite (CsPbX 3, X = Cl, Br,并且我或 Cl/Br 和 I/Br ) 由在空中的在 octadecene 的先锋的直接加热的 nanocrystals (NC ) 。试验性的结果证明同样准备的 CsPbX 3 nanocrystals 的粒子尺寸和作文能被反应温度的一个简单变化成功地调节。同样准备的 nanocrystals 的排放山峰位置能方便地从 UV 被调节到 NIR (360-700 nm ) 区域,和同样获得的样品(绿、红的排出物) 的量收益罐头活动范围直到 87% 。结构和同样获得的 NC 的化学作文被传播电子显微镜学, X 光检查衍射,和元素的分析描绘。这建议合成线路能与一个批反应产出大量高质量的 NC,并且能为基于 perovskite 的轻射出、光电的太阳能电池的进一步的应用程序铺平道路,通常在克规模上。 | Xu Chen Lucheng Peng Keke Huang Zhan Shi Renguo Xie Wensheng Yang | 2016 | Nano Research2016，9，7： | 8 |
| 11 | Effect of ZSM-5 zeolite morphology on the catalytic performance of the alkylation of toluene with methanol显示文摘A series of ZSM-5 zeolites, with the morphologies of sphere, sphere with cubic particles on the surface, and cubic particles, were synthesized by hydrothermal method using n-butylamine as the template, assisted by the addition of NaCl and crystal seed. X-ray diffraction(XRD),scanning electron microscope(SEM), X-ray fluorescence(XRF) and temperature-programmed desorption of ammonia(NH3-TPD) were used to characterize these samples. The samples were tested with toluene methylation reaction. The modified sample composed of spherical particles with 3 μm crystal particles on the surface had a para-xylene selectivity of 95% and maintained 79% of the initial conversion after running the reaction for 50 h. This modified sample showed the best stability among the tested three modified samples. | Hongyu Wu Min Liu Wei Tan Keke Hou Anfeng Zhang Yiren Wang Xinwen Guo | 2014 | Journal of Energy Chemistry2014，23，4： | 8 |
| 12 | Large-scale synthesis of single-source, thermally stable, and dual-emissive Mn-doped Zn-Cu-ln-S nanocrystals for bright white light-emitting diodes显示文摘 | Lucheng Peng Dongze Li Zhuolei Zhang Keke Huang Ying Zhang Zhan Shi Renguo Xie Wensheng Yang | 2015 | Nano Research2015，8，10： | 7 |
| 13 | Hypoxia-stressed cardiomyocytes promote early cardiac differentiation of cardiac stem cells through HIF-1α/Jagged1/Notch1 signaling显示文摘Hypoxia is beneficial for the differentiation of stem cells transplanted for myocardial injury,but mechanisms underlying this benefit remain unsolved. Here, we report the impact of hypoxia-induced Jagged1 expression in cardiomyocytes(CMs) for driving the differentiation of cardiac stem cells(CSCs).Forced hypoxia-inducible factor 1α(HIF-1α) expression and physical hypoxia(5% O_2) treatment could induce Jagged1 expression in neonatal rat CMs. Pharmacological inhibition of HIF-1α by YC-1 attenuated hypoxia-promoted Jagged1 expression in CMs. An ERK inhibitor(PD98059), but not inhibitors of JNK(SP600125), Notch(DAPT), NF-κB(PTDC), JAK(AG490), or STAT3(Stattic) suppressed hypoxiainduced Jagged1 protein expression in CMs. c-Kit^+ CSCs isolated from neonatal rat hearts using a magnetic-activated cell sorting method expressed GATA4, SM22α or vWF, but not Nkx2.5 and cTnI.Moreover, 87.3% of freshly isolated CSCs displayed Notch1 receptor expression. Direct co-culture of CMs with BrdU-labeled CSCs enhanced CSCs differentiation, as evidenced by an increased number of BrdU^+/Nkx2.5^+ cells, while intermittent hypoxia for 21 days promoted co-culture-triggered differentiation of CSCs into CM-like cells. Notably, YC-1 and DAPT attenuated hypoxia-induced differentiation.Our results suggest that hypoxia induces Jagged1 expression in CMs primarily through ERK signaling,and facilitates early cardiac lineage differentiation of CSCs in CM/CSC co-cultures via HIF-1α/Jagged1/Notch signaling. | Keke Wang Ranran Ding Yanping Ha Yanan Jia Xiaomin Liao Sisi Wang Rujia Li Zhihua Shen Hui Xiong Junli Guo Wei Jie | 2018 | Acta Pharmaceutica Sinica B2018，8，5： | 7 |
| 14 | Origin of CO_2 in natural gas from the Triassic Feixianguan Formation of Northeast Sichuan Basin显示文摘The natural gas from the Triassic Feixianguan Formation of Northeast Sichuan Basin contains high H2S whereas relatively low CO2 concentrations and the CO2 display high δ13C values (ranging from -5.81‰ to 3.3‰ (PDB)). This seems to contradict the conventional wisdom that TSR should be a primary source of CO2 in natural gas from the Feixianguan Formation. In contrast, many authigenic calcite samples from these sites display very low δ13C values (ranging from -18.4‰ to -10.3‰ (PDB)). This suggests that the carbon from TSR source dominated the formation of calcite whereas the carbon from inorganic source came into CO2 in natural gas. In order to assess the origin of CO2 from these H2S-rich sites, we have calculated the relative contributions of organic and inorganic carbon sources to the CO2 and authigenic calcite. The organic carbon source possibly originated from TSR, whereas the inorganic one might be generated from marine carbonates dissolution. This calculation is based on the carbon isotopic compositions of CO2 and authigenic calcite as well as an isotopic mass balance. The results show that the contribution of organic carbon source to the CO2 is only 2%, whereas that to authigenic calcite is as high as 43% on average. Such results combined with thermodynamic evidence indicate that the isotopically light CO2 produced by TSR process may contribute to authigenic calcite precipitation during burial diagenesis. Distinguishable from Ordovician reservoir of Tarim Basin, Feixianguan reservoir of Northeast Sichuan Basin experienced rapid tectonic uplift due to Yanshanian movement after TSR occurred. Such tectonic event could induce temperature decrease and further promote carbonates dissolution. During these processes, secondary porosity has developed in Feixianguan carbonate reservoirs. Therefore, much attention should be paid to the structural highs in search of high quality carbonate reservoirs. | HUANG SiJing, HUANG KeKe, TONG HongPeng, LIU LiHong, SUN Wei & ZHONG QianQian State Key Lab of Oil and Gas Reservoir Geology and Exploitation, Institute of Sedimentary Geology, Chengdu University of Technology, Chengdu 610059, China | 2010 | Science China Earth Sciences2010，53，5： | 7 |
| 15 | Analyses of surrogate models for calculating thermophysical properties of aviation kerosene RP-3 at supercritical pressures显示文摘Aviation kerosene is commonly used in combustion and regenerative engine cooling processes in propulsion and power-generation systems,including rocket,scramjet,and advanced gas turbine engines.In this paper,many surrogate models proposed in the open literature are examined for their applicability and accuracy in calculating thermodynamic and transport properties of the China aviation kerosene RP-3 at supercritical pressures,based on the extended corresponding-states methods.The enthalpy change from endothermic decomposition and low heating value from combustion of the jet fuel are also evaluated.Results from a number of simple and representative surrogate models,which contain species components ranging from 1 to10,are analyzed in detail.Data analyses indicate that a surrogate model with four species is the best choice for thermophysical property calculations under the tested conditions,with fluid temperature up to 650 K at various supercritical pressures.The surrogate model is particularly accurate in predicting the pseudo-critical temperature of aviation kerosene RP-3 at a supercritical pressure.A simple surrogate model containing the n-decane species and a surrogate model containing 10 species are the other two acceptable options.The work conducted herein is of practical importance for theoretical analyses and numerical simulations of various physicochemical processes at engine operating conditions. | XU KeKe MENG Hua | 2015 | Science China(Technological Sciences)2015，58，3： | 6 |
| 16 | Topology Recovery Technique for Complex Freeform Surface Model after Local Geometry Repair显示文摘Intersections and discontinuities commonly arise in surface modeling and cause problems in downstream operations.Local geometry repair,such as cover holes or replace bad surfaces by adding new surface patches for dealing with inconsistencies among the confluent region,where multiple surfaces meet,is a common technique used in CAD model repair and reverse engineering.However,local geometry repair destroys the topology of original CAD model and increases the number of surface patches needed for freeform surface shape modeling.Consequently,a topology recovery technique dealing with complex freeform surface model after local geometry repair is proposed.Firstly,construct the curve network which determine the geometry and topology properties of recovery freeform surface model;secondly,apply freeform surface fitting method to create B-spline surface patches to recover the topology of trimmed ones.Corresponding to the two levels of enforcing boundary conditions on a B-spline surface,two solution schemes are presented respectively.In the first solution scheme,non-constrained B-spline surface fitting method is utilized to piecewise recover trimmed confluent surface patches and then employs global beautification technique to smoothly stitch the recovery surface patches.In the other solution scheme,constrained B-spline surface fitting technique based on discretization of boundary conditions is directly applied to recover topology of surface model after local geometry repair while achieving G 1 continuity simultaneously.The presented two different schemes are applied to the consistent surface model,which consists of five trimmed confluent surface patches and a local consistent surface patch,and a machine cover model,respectively.The application results show that our topology recovery technique meets shape-preserving and G 1 continuity requirements in reverse engineering.This research converts the problem of topology recovery for consistent surface model to the problem of constructing G 1 patches from a given curve network,and provides a new idea to model repairing study. | BIAN Keke KE Yinglin | 2013 | Chinese Journal of Mechanical Engineering2013，26，1： | 6 |
| 17 | Progress on sensors based on nanomaterials for rapid detection of heavy metal ions显示文摘The heavy metal ions,especially Cd^(2+),Pb^(2+) and Hg^(2+),show extremely hazard to the environment and human being.The measurement of heavy metal ions using sensors is catching more and more attention for its advantages of high sensitivity and selectivity,low-cost,convenience to handle and rapid detection.In recent years,nanomaterials such as gold nanoparticles(NPs),magnetic nanoparticles,graphene and nanocomposite materials are applied in sensors for improving sensitivity and selectivity,making the research on electrochemical(EC) sensors,spectrometric biosensors and colorimetric biosensors become a hot spot in the application to investigate heavy metal ions,in particular,Cd^(2+),Pb^(2+) and Hg^(2+).In this short review,the research of advanced detection of Cd^(2+),Pb^(2+) and Hg^(2+) and its progress based on nanomaterial sensors in recent years is reviewed. | Yuan Liu Yan Deng Hongming Dong Keke Liu Nongyue He | 2017 | Science China Chemistry2017，60，3： | 6 |
| 18 | Cenozoic Evolution of Sediments and Climate Change and Response to Tectonic Uplift of the Northeastern Tibetan Plateau显示文摘Through a comprehensive study of magnetostratigraphy and sedimentology of several basins in the northeastern Tibetan Plateau, we reveal that the study area mainly experienced six tectonic uplift stages at approximately 52 Ma, 34–30 Ma, 24–20 Ma, 16–12 Ma, 8–6 Ma, and 3.6–2.6 Ma. Comprehensive analyses of pollen assemblages from the Qaidam, Linxia, Xining, and West Jiuquan Basins show that the northeastern Tibetan Plateau has undergone six major changes in vegetation types and climate: 50–40 Ma for the warm-humid forest vegetation, 40–23 Ma for the warm-arid and temperate-arid forest steppe vegetation, 23–18.6 Ma for the warm-humid and temperatehumid forest vegetation, 18.6–8.5 Ma for the warm-humid and cool-humid forest steppe vegetation, 8.6–5 Ma for the temperate sub-humid savanna steppe vegetation, and 5–1.8 Ma for the cold-arid steppe vegetation. Comprehensive comparisons of tectonic uplift events inferred from sedimentary records, climatic changes inferred from pollen, and global climate changes show that in the northeastern Tibetan Plateau the climate in the Paleogene at low altitude was mainly controlled by the global climate change, while that in the Neogene interval with high altitude landscapes of mountains and basins is more controlled by altitude and morphology. | LIANG Xia JI Junliang LU Jingfang KE Xue AI Keke XU Yadong SONG Bowen | 2014 | Acta Geologica Sinica(English Edition)2014，88，3： | 5 |
| 19 | The receptor-like cytoplasmic kinase RIPK regulates broad-spectrum ROS signaling in multiple layers of plant immune system显示文摘Production of reactive oxygen species(ROS)via the activity of respiratory burst oxidase homologs(RBOHs)plays a vital role in multiple layers of the plant immune system,including pathogen-associated molecular pattern-triggered immunity(PTI),damage-associated molecular pattern-triggered immunity(DTI),effector-triggered immunity(ETI),and systemic acquired resistance(SAR).It is generally established that RBOHD is activated by different receptor-like cytoplasmic kinases(RLCKs)in response to various immune elicitors.In this study,we showed that RPM1-INDUCED PROTEIN KINASE(RIPK),an RLCK VII subfamily member,contributes to ROS production in multiple layers of plant immune system.The ripk mutants showed reduced ROS production in response to treatment with all examined immune elicitors that trigger PTI,DTI,ETI,and SAR.We found that RIPK can directly phosphorylate the N-terminal region of RBOHD in vitro,and the levels of phosphorylated S343/S347 residues of RBOHD are sigfniciantly lower in ripk mutants compared with the wild type upon treatment with all tested immune elicitors.We further demonstrated that phosphorylation of RIPK is required for its function in regulating RBOHD-mediated ROS production.Similar to rbohd,ripk mutants showed reduced stomatal closure and impaired SAR,and were susceptible to the necrotrophic bacterium Pectobacterium carotovorum.Collectively,our results indicate that RIPK regulates broad-spectrum RBOHD-mediated ROS signaling during PTI,DTI,ETI,and SAR,leading to subsequent RBOHD-dependent immune responses. | Ping Li Lulu Zhao Fan Qi Nang Myint Phyu Sin Htwe Qiuying Li Dawei Zhang Fucheng Lin Keke Shang-Guan Yan Liang | 2021 | Molecular Plant2021，14，10： | 5 |
| 20 | Predictive cruise control for heavy trucks based on slope information under cloud control system显示文摘With the advantage of fast calculation and map resources on cloud control system(CCS), cloud-based predictive cruise control(CPCC) for heavy trucks has great potential to improve energy efficiency, which is significant to achieve the goal of national carbon neutrality. However, most investigations focus on the on-board predictive cruise control(PCC) system,lack of research on CPCC architecture under CCS. Besides, the current PCC algorithms have the problems of a single control target and high computational complexity, which hinders the improvement of the control effect. In this paper, a layered architecture based on CCS is proposed to effectively address the realtime computing of CPCC system and the deployment of its algorithm on vehicle-cloud. In addition, based on the dynamic programming principle and the proposed road point segmentation method(RPSM), a PCC algorithm is designed to optimize the speed and gear of heavy trucks with slope information. Simulation results show that the CPCC system can adaptively control vehicle driving through the slope prediction, with fuel-saving rate of 6.17% in comparison with the constant cruise control. Also,compared with other similar algorithms, the PCC algorithm can make the engine operate more in the efficient zone by cooperatively optimizing the gear and speed. Moreover, the RPSM algorithm can reconfigure the road in advance, with a 91% roadpoint reduction rate, significantly reducing algorithm complexity.Therefore, this study has essential research significance for the economic driving of heavy trucks and the promotion of the CPCC system. | LI Shuyan WAN Keke GAO Bolin LI Rui WANG Yue LI Keqiang | 2022 | Journal of Systems Engineering and Electronics2022，33，4： | 5 |
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