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| 1 | Low-Dimensional Halide Perovskites and Their Advanced Optoelectronic Applications显示文摘Metal halide perovskites are crystalline materials originally developed out of scientific curiosity. They have shown great potential as active materials in optoelectronic applications. In the last 6 years, their certified photovoltaic efficiencies have reached 22.1%. Compared to bulk halide perovskites, low-dimensional ones exhibited novel physical properties. The photoluminescence quantum yields of perovskite quantum dots are close to 100%. The external quantum efficiencies and current efficiencies of perovskite quantum dot light-emitting diodes have reached 8% and 43 cd A^(-1),respectively, and their nanowire lasers show ultralow-threshold room-temperature lasing with emission tunability and ease of synthesis. Perovskite nanowire photodetectors reached a responsivity of 10 A W^(-1)and a specific normalized detectivity of the order of 10^(12 )Jones. Different from most reported reviews focusing on photovoltaic applications, we summarize the rapid progress in the study of low-dimensional perovskite materials, as well as their promising applications in optoelectronic devices. In particular, we review the wide tunability of fabrication methods and the state-of-the-art research outputs of low-dimensional perovskite optoelectronic devices. Finally, the anticipated challenges and potential for this exciting research are proposed. | Jian Zhang Xiaokun Yang Hui Deng Keke Qiao Umar Farooq Muhammad Ishaq Fei Yi Huan Liu Jiang Tang Haisheng Song | 2017 | Nano-Micro Letters2017，9，3： | 10 |
| 2 | Measuring Tourist’s Water Footprint in a Mountain Destination of Northwest Yunnan, China显示文摘Monitoring and minimizing tourist’s water consumption is essential for the sustainable development of mountain destinations in the world. However, available data and a generally accepted protocol on such measurement are still limited. This study uses water footprint accounting to quantify tourist’s water demand in the Liming valley, a World Heritage site and a rapidly growing tourism destination in Northwest Yunnan, China. Both the water for direct and indirect use is taken into account based on the consumptive behavior of the tourists in the valley. Data were collected through guesthouse monitoring and a tourist survey in the 2005 tourist season. The results indicate that an average tourist leaves behind a footprint of 5.2 m3 on local water resources per day. Food production and waste dilution are the two most important water consumption factors. The results also show tourists consume more water than the local residents on per capita basis. This suggests more commitment is necessary to cope with this stress by individual tourists. Management implications to make water use more sustainable in mountain destinations are derived from this study. | YANG Mingyu Luc HENS Robert DE WULF OU Xiaokun | 2011 | Journal of Mountain Science2011，8，5： | 7 |
| 3 | Overactive bladder symptom score to evaluate efficacy of solifenacin for the treatment of overactive bladder symptoms显示文摘 | Liu Ming Wang Jianye Yang Yong An Ruihua Wen Jianguo Guan Zhichen Zheng Shaobin Wang Dongwen Song Bo Liao Limin Guo Hongqian Xiao Jiaquan Sun Yinghao Shen Zhoujun Kong Chuize He Dalin Huang Yiran Wang Xiaofeng Zhang Xu Li Hanzhong Huang Jian Zhao Xiaokun Zeng Puqing Song Xishuang Ye Zhangqun | 2014 | Chinese Medical Journal2014，，2： | 7 |
| 4 | FGF1^(△HBS) prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression显示文摘As a classically known mitogen,fibroblast growth factor 1(FGF1)has been found to exert other pleiotropic functions such as metabolic regulation and myocardial protection.Here,we show that serum levels of FGF1 were decreased and positively correlated with fraction shortening in diabetic cardiomyopathy(DCM)patients,indicating that FGF1 is a potential therapeutic target for DCM.We found that treatment with a FGF1 variant(FGF1^(△HBS))with reduced proliferative potency prevented diabetes-induced cardiac injury and remodeling and restored cardiac function.RNA-Seq results obtained from the cardiac tissues of db/db mice showed significant increase in the expression levels of anti-oxidative genes and decrease of Nur77 by FGF1AHBS treatment.Both in vivo and in vitro studies indicate that FGF1^(△HBS) exerted these beneficial effects by markedly reducing mitochondrial fragmentation,reactive oxygen species(ROS)generation and cytochrome c leakage and enhancing mitochondrial respiration rate and β-oxidation in a 5;AMP-activated protein kinase(AMPK)/Nur77-dependent manner,all of which were not observed in the AMPK null mice.The favorable metabolic activity and reduced proliferative properties of FGF1^(△HBS) testify to its promising potential for use in the treatment of DCM and other metabolic disorders. | Dezhong Wang Yuan Yin Shuyi Wang Tianyang Zhao Fanghua Gong Yushuo Zhao Beibei Wang Yuli Huang Zizhao Cheng Guanghui Zhu Zengshou Wang Yang Wang Jun Ren Guang Liang Xiaokun Li Zhifeng Huang | 2021 | Signal Transduction and Targeted Therapy2021，6，4： | 6 |
| 5 | CXCL16 deficiency attenuates acetaminopheninduced hepatotoxicity through decreasing hepatic oxidative stress and inflammation in mice显示文摘Chemokine C-X-C ligand 16 (CXCL16 ) ,一种单个通行证的类型我属于 CXC chemokine 家庭的膜蛋白质,与在肝损害的煽动性的反应有关。在现在的学习,我们调查了 CXCL16 的 pathophysiological 角色,唯一的膜界限 chemokine,在导致的 acetaminophen (APAP ) 在老鼠的 hepatotoxicity。老鼠与 APAP 被注射,并且血和织物样品在不同时间点被收获。浆液高活动性的组盒子 1 并且 CXCL16 层次被三明治免疫分析确定。肝织物节与 hematoxylin 曙红或与染色的 dihydroethidium 被染色。CXCL16 和另外的 cytokines 的表情被即时聚合酶链反应检验。Ly6-B, p-jun N 终端 kinase (p-JNK ) ,和 JNK 表情被西方的污点分析测量。细胞内部的谷胱甘肽,反应的氧种类,和 malondialdehyde 层次也被测量。APAP 服药过量增加了肝的 CXCL16 mRNA 和浆液 CXCL16 蛋白质层次。CXCL16 缺乏的老鼠显著地展出了更少的肝损害和肝的坏死,以及更低的死亡比野类型(WT ) 响应 APAP 服药过量处理的老鼠。提高的 APAP 在 WT 老鼠的呼吸的链激活,它是强烈在 CXCL16 大美人老鼠颠倒了的氧化应力和减少的 mitochondrial 的生产。另外, CXCL16 缺乏禁止了嗜中性的渗入和 APAP 服药过量处理触发的 proinflammatory cytokines 的生产。我们的学习表明 CXCL16 是对导致 APAP 的 hepatotoxicity 的肝免疫者反应的一个批评管理者,因此由指向 CXCL16 为导致药的尖锐的肝失败的处理提供潜在的策略。 | Hong Wang Yihui Shao Saisai Zhang Anqi Xie Yanna Ye Lihua Shi Leigang Jin Xuebo Pan Zhuofeng Lin Xiaokun Li Shulin Yang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，6： | 4 |
| 6 | ImmunoCytTM and cytology for diagnosis of bladder carcinoma:a meta analysis显示文摘 | Yang Minggen Zheng Zhouda Zhuang Zhiming Zhao Xiaokun Xu Zhenqiang Lin Haili | 2014 | Chinese Medical Journal2014，，4： | 3 |
| 7 | Challenges and strategies in high-accuracy manufacturing of the world’s largest SiC aspheric mirror显示文摘In the process of manufacturing the world’s largest silicon carbide(SiC)aspheric mirror,the primary difficulties are mirror blank preparation,asphere fabrication,and testing,as well as cladding and coating.Specifically,the challenges include the homogeneity of the complicated structure casting,accuracy and efficiency of the fabrication process,print-through effect,fidelity and precision of test procedure,stress and denseness of cladding process,the dynamic range of interferometric measurement,and air turbulence error due to the long optical path.To break through such a barrier of difficulties,we proposed the water-soluble room temperature vanishing mold and gel casting technology,homogeneous microstructure reaction-formed joint technology,nano-accuracy efficient compound fabrication,gravity unloading technology,high-denseness low-defect physical vapor deposition(PVD)Si-cladding technology,test data fusion method,and time-domain averaging method,etc.Based on the proposed technologies and methods,we have accomplished the world’s largest SiC aspheric mirror with a size of φ4.03 m.The impressive performance of the SiC aspheric mirror is validated by the characteristics of the fabricated SiC aspheric mirror.The aerial density of the SiC blank is less than 120 kg/m^(2),surface shape test accuracy is better than 6 nm RMS,thickness inhomogeneity of the cladding layer is less than 5%,and the final surface figure error and roughness are 15.2 nm RMS and 0.8 nm RMS,respectively. | Xuejun Zhang Haixiang Hu Xiaokun Wang Xiao Luo Ge Zhang Wenxing Zhao Xiaoyi Wang Zhenyu Liu Ling Xiong Erhui Qi Congcong Cui Yanchao Wang Yingjie Li Xu Wang Longxiang Li Yang Bai Qiang Cheng Zhiyu Zhang Ruigang Li Wa Tang Xuefeng Zeng Weijie Deng Feng Zhang | 2022 | Light(Science & Applications)2022，11，12： | 3 |
| 8 | Hydroiodic Acid Additive Enhanced the Performance and Stability of PbS-QDs Solar Cells via Suppressing Hydroxyl Ligand显示文摘The recent emerging progress of quantum dot ink(QD-ink)has overcome the complexity of multiple-step colloidal QD(CQD)film preparation and pronouncedly promoted the device performance.However,the detrimental hydroxyl(OH)ligands induced from synthesis procedure have not been completely removed.Here,a halide ligand additive strategy was devised to optimize QD-ink process.It simultaneously reduced sub-bandgap states and converted them into iodide-passivated surface,which increase carrier mobility of the QDs films and achieve thicker absorber with improved performances.The corresponding power conversion efficiency of this optimized device reached 10.78%.(The control device was 9.56%.)Therefore,this stratege can support as a candidate strategy to solve the QD original limitation caused by hydroxyl ligands,which is also compatible with other CQD-based optoelectronic devices. | Xiaokun Yang Ji Yang Jahangeer Khan Hui Deng Shengjie Yuan Jian Zhang Yong Xia Feng Deng Xue Zhou Farooq Umar Zhixin Jin Haisheng Song Chun Cheng Mohamed Sabry Jiang Tang | 2020 | Nano-Micro Letters2020，12，3： | 2 |
| 9 | Inefficiency of C3H/HeN Mice to Control Chlamydial Lung Infection Correlates with Downregulation of Neutrophil Activation during the Late Stage of Infection显示文摘我们以前报导在 C3H/HeN (C3H ) 老鼠的 neutrophils 的巨大的渗入不能高效地控制感染和力量贡献的 Chlamydia muridarum (厘米) 到肺感染的这些老鼠的高危险性。为了推进,在 chlamydial 感染期间在 C3H 鼠标定义嗜中性的回答的性质,分别地,我们检验与 neutrophils 渗入和激活有关的粘附分子和 CD11b 的表达式后面的 intranasal 厘米感染。结果证明 selectins (E-selectin, P-selectin 和 L-selectin ) 的表示,和在 C3H 老鼠的肺的细胞间的房间粘附 molecule-1 (ICAM-1 ) 比在 C57BL/6 (B6 ) 更显著地增加了老鼠,更抵抗的紧张。这些结果在 C3H 老鼠与巨大的 neutrophils 渗入相关很好。相反,外部血上的 CD11b 表示和在 C3H 鼠标的肺 neutrophils 在感染(白天 14 ) 的迟了的噬菌体期间与 B6 鼠标相比展出了重要减小。这些调查结果建议在 C3H 鼠标的粘附分子的高级表达式可以提高 neutrophils 招募到肺,但是 neutrophils 上的 CD11b 表示的衰落可以稀释嗜中性的功能。因此, neutrophils 上的 CD11b 下面规定可以贡献 C3H 老鼠的失败控制 chlamydial 肺感染。 | Xiaofei Tang Xiaokun Bu Naihong Zhang Xiaoxia Li Huanjun Huang Hong Bai Xi Yang | 2009 | Cellular & Molecular Immunology2009，6，4： | 2 |
| 10 | Preliminary design of an SCO_(2) conversion system applied to the sodium cooled fast reactor显示文摘The supercritical carbon dioxide(SCO_(2))Brayton cycle has become an ideal power conversion system for sodium-cooled fast reactors(SFR)due to its high efficiency,compactness,and avoidance of sodiumwater reaction.In this paper,the 1200 MWe large pool SFR(CFR1200)is used as the heat source of the system,and the sodium circuit temperature and the heat load are the operating boundaries of the cycle system.The performance of different SCO_(2) Brayton cycle systems and changes in key equipment performance are compared.The study indicates that the inter-stage cooling and recompression cycle has the best match with the heat source characteristics of the SFR,and the cycle efficiency is the highest(40.7%).Then,based on the developed system transient analysis program(FR-Sdaso),a pool-type SFR power plant system analysis model based on the inter-stage cooling and recompression cycle is established.In addition,the matching between the inter-stage cooling recompression cycle and the SFR during the load cycle of the power plant is studied.The analysis shows that when the nuclear island adopts the flow-advanced operation strategy and the carbon dioxide flowrate in the SCO_(2) power conversion system is adjusted with the goal of maintaining the sodium-carbon dioxide heat exchanger sodium side outlet temperature unchanged,the inter-stage cooling recompression cycle can match the operation of the SFR very well. | Hongyi YANG Xiaoyan YANG Jun YANG Quanbin ZHAO Xiaokun WANG Daotong CHONG Chanjuan TANG Chengyuan JIANG | 2021 | Frontiers in Energy2021，15，4： | 1 |
| 11 | DNA methylation as an early diagnostic marker of cancer (Review)显示文摘 | Yuanyuan Dong Haiyang Zhao Haiyan Li Xiaokun Li Shulin Yang | 2014 | Biomedical Reports2014，，3： | 1 |
| 12 | In Vitro and in Vivo Antitumor Activity of Scutebarbatine A onHuman Lung Carcinoma A549 Cell Lines显示文摘 | XiaoKun Yang ZhaoXia Xu | 2014 | Molecules2014，19，： | 1 |
| 13 | A dynamicconstraint satisfaction approach for configuring structuralproducts under mass customization 显示文摘 | DONG Yang DONG Ming CHANG Xiaokun | 2012 | Engineering Applica-tions of Artificial Intelligence2012，25，8： | 1 |
| 14 | Inhibition of LPS‐induced production of inflammatory factors in the macrophages by mono‐carbonyl analogues of curcumin显示文摘 | Guang Liang Huiping Zhou Yi Wang Emily C. Gurley Biao Feng Li Chen Jian Xiao Shulin Yang Xiaokun Li | 2009 | Journal of Cellular and Molecular Medicine (b)2009，，9： | 1 |
| 15 | Bioprinted constructs that simulate nerve-bone crosstalk to improve microenvironment for bone repair显示文摘Crosstalk between nerves and bone is essential for bone repair,for which Schwann cells(SCs)are crucial in the regulation of the microenvironment.Considering that exosomes are critical paracrine mediators for intercellular communication that exert important effects in tissue repair,the aim of this study is to confirm the function and molecular mechanisms of Schwann cell-derived exosomes(SC-exos)on bone regeneration and to propose engineered constructs that simulate SC-mediated nerve-bone crosstalk.SCs promoted the proliferation and differentiation of bone marrow mesenchymal stem cells(BMSCs)through exosomes.Subsequent molecular mechanism studies demonstrated that SC-exos promoted BMSC osteogenesis by regulating the TGF-βsignaling pathway via let-7c-5p.Interestingly,SC-exos promoted the migration and tube formation performance of endothelial progenitor cells.Furthermore,the SC-exos@G/S constructs were developed by bioprinting technology that simulated SC-mediated nerve-bone crosstalk and improved the bone regeneration microenvironment by releasing SC-exos,exerting the regulatory effect of SCs in the microenvironment to promote innervation,vascularization,and osteogenesis and thus effectively improving bone repair in a cranial defect model.This study demonstrates the important role and underlying mechanism of SCs in regulating bone regeneration through SC-exos and provides a new engineered strategy for bone repair. | Tianchang Wang Wentao Li Yuxin Zhang Xiang Xu Lei Qiang Weiqiang Miao Xiaokun Yue Xin Jiao Xianhao Zhou Zhenjiang Ma Shuai Li Muliang Ding Junfeng Zhu Chi Yang Hui Wang Tao Li Xin Sun Jinwu Wang | 2023 | Bioactive Materials2023，，9： | 1 |
| 16 | Zinc supplementation partially prevents renal pathological changes in diabetic rats显示文摘 | Yunan Tang Qin Yang Jiayin Lu Xiaolin Zhang Di Suen Yi Tan Litai Jin Jian Xiao Rujia Xie Madhavi Rane Xiaokun Li Lu Cai | 2010 | The Journal of Nutritional Biochemistry2010，，3： | 1 |
| 17 | SARS-CoV-2 Surveillance Through China Influenza Surveillance Information System—China,December 1,2022 to February 12,2023显示文摘Introduction:The World Health Organization(WHO)proposed using influenza surveillance systems to carry out coronavirus disease 2019(COVID-19)surveillance due to the similarity between the two diseases in some respiratory symptoms.To assess the prevalence of COVID-19,we analyzed the influenzalike illness(ILI)and positive rate of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)detections in ILI patients reported to the influenza Surveillance Information System(CNISIS)since late 2022.Methods:Data related to ILI were reported by national surveillance sentinel hospitals.Positive testing for SARS-CoV-2 and influenza viruses was conducted using real-time reverse transcription polymerase chain reaction(rRT-PCR)detection by the national influenza surveillance network laboratories.Surveillance data were reported to CNISIS.Results:Beginning on December 12,2022(Week 50),the ILI percentage increased dramatically,peaking in Week 51 at 12.1%.Subsequently,the ILI percentage began to decline rapidly from Week 52,2022,and by Week 6,2023(February 6-12),the ILI and ILI percentage had returned to the levels observed at the beginning of December 2022.From December 1,2022 to February 12,2023,115,844 specimens were tested for both SARS-CoV-2 and influenza virus.Of these,30,381(26.2%)were positive for SARSCoV-2 and 1,763(1.5%)were positive for influenza virus.The positive rate of SARS-CoV-2 tests peaked at 74.1%around December 23 and 25.Conclusions:Sentinel-based surveillance,previously established for influenza,is an effective way to track the circulation trend of SARS-CoV-2 during community-level epidemics.There was no coprevalence of SARS-CoV-2 and influenza virus during the outbreak of SARS-CoV-2,even during the winter influenza season.However,it is important to remain vigilant for the potential rise of influenza activities following the COVID-19 epidemic. | Xiaoxu Zeng Yiran Xie Xiaokun Yang Zhibin Peng Jing Tang Lei Yang Shuxia Lin Jun Han Yanping Zhang Dayan Wang | 2023 | China CDC weekly2023，5，7： | 1 |
| 18 | Lagrangian eddies in the Northwestern Pacifi c Ocean显示文摘The Lagrangian eddies in the western Pacifi c Ocean are identifi ed and analysed based on Maps of Sea Level Anomaly(MSLA)data from 1998 to 2018.By calculating the Lagrangian eddy advected by the AVISO velocity fi eld,we analyzed the variations in Lagrangian eddies and the average transport eff ects on diff erent time scales.By introducing the Niño coeffi cient,the lag response of the Lagrangian eddy to El Niño is found.These data are helpful to further explore the role of mesoscale eddies in ocean energy transfer.Through normalized chlorophyll data,we observed chlorophyll aggregation and hole eff ects caused by Lagrangian eddies.These fi ndings demonstrate the important role of Lagrangian eddies in material transport.The transportation volume of the Lagrangian eddy is calculated quantitatively,and several major transport routes have been identifi ed,which helps us to more accurately and objectively estimate the transport capacity of Lagrangian eddies in the western Pacifi c Ocean. | Qiu HE Fenglin TIAN Xiaokun YANG Ge CHEN | 2022 | Journal of Oceanology and Limnology2022，40，1： | 1 |
| 19 | Synthesis and anti-inflammatory evaluation of novel mono-carbonyl analogues of curcumin in LPS-stimulated RAW 264.7 macrophages显示文摘 | Chengguang Zhao Yuepiao Cai Xuzhi He Jianling Li Li Zhang Jianzhang Wu Yunjie Zhao Shulin Yang Xiaokun Li Wulan Li Guang Liang | 2010 | European Journal of Medicinal Chemistry2010，，12： | 1 |
| 20 | Improving the Performance of PbS Quantum Dot Solar Cells by Optimizing ZnO Window Layer显示文摘Comparing with hot researches in absorber layer,window layer has attracted less attention in PbS quantum dot solar cells(QD SCs). Actually, the window layer plays a key role in exciton separation, charge drifting, and so on.Herein, ZnO window layer was systematically investigated for its roles in QD SCs performance. The physical mechanism of improved performance was also explored. It was found that the optimized ZnO films with appropriate thickness and doping concentration can balance the optical and electrical properties, and its energy band align well with the absorber layer for efficient charge extraction. Further characterizations demonstrated that the window layer optimization can help to reduce the surface defects, improve the heterojunction quality, as well as extend the depletion width. Compared with the control devices, the optimized devices have obtained an efficiency of 6.7% with an enhanced V_(oc) of 18%, J_(sc) of 21%, FF of 10%, and power conversion efficiency of 58%. The present work suggests a useful strategy to improve the device performance by optimizing the window layer besides the absorber layer. | Xiaokun Yang Long Hu Hui Deng Keke Qiao Chao Hu Zhiyong Liu Shengjie Yuan Jahangeer Khan Dengbing Li Jiang Tang Haisheng Song Chun Cheng | 2017 | Nano-Micro Letters2017，9，2： | 0 |
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