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| 1 | Rhubarb extract partially improves mucosal integrity in chemotherapy-induced intestinal mucositis显示文摘AIM To investigate the effects of orally gavaged aqueous rhubarb extract(RE) on 5-fluorouracil(5-FU)-induced intestinal mucositis in rats. METHODS Female Dark Agouti rats(n = 8/group) were gavaged daily(1 mL) with water, high-dose RE(HDR; 200 mg/kg) or low-dose RE(LDR; 20mg/kg) for eight days. Intestinal mucositis was induced(day 5) with 5-FU(150 mg/kg) via intraperitoneal injection. Intestinal tissue samples were collected for myeloperoxidase(MPO) activity and histological examination. Xenopus oocytes expressing aquaporin 4 water channels were prepared to examine the effect of aqueous RE on cell volume, indicating a potential mechanism responsible for modulating net fluid absorption and secretion in the gastrointestinal tract. Statistical significance was assumed at P < 0.05 by one-way ANOVA. RESULTS B o d y w e i g h t w a s s i g n i f i c a n t l y r e d u c e d i n r a t s administered 5-FU compared to healthy controls(P < 0.01). Rats administered 5-FU significantly increased intestinal MPO levels(≥ 307%; P < 0.001), compared to healthy controls. However, LDR attenuated this effect in 5-FU treated rats, significantly decreasing ileal MPO activity(by 45%; P < 0.05), as compared to 5-FU controls. 5-FU significantly reduced intestinal mucosal thickness(by ≥ 29% P < 0.001) as compared to healthy controls. LDR significantly increased ileal mucosal thickness in 5-FU treated rats(19%; P < 0.05) relative to 5-FU controls. In xenopus oocytes expressing AQP4 water channels, RE selectively blocked water influx into the cell, induced by a decrease in external osmotic pressure. As water efflux was unaltered by the presence of extracellular RE, the directional flow of water across the epithelial barrier, in the presence of extracellular RE, indicated that RE may alleviate water loss across the epithelial barrier and promote intestinal health in chemotherapy-induced intestinal mucositis.CONCLUSION In summary, low dose RE improves selected parameters of mucosal integrity and reduces ileal inflammation, manifesting from 5-FU-induced intestinal mucositis. | Juliana E Bajic Georgina L Eden Lorrinne S Lampton Ker Y Cheah Kerry A Lymn Jinxin V Pei Andrea J Yool Gordon S Howarth | 2016 | World Journal of Gastroenterology2016，22，37： | 3 |
| 2 | A framework infrageneric classification of Carex (Cyperaceae) and its organizing principles显示文摘Phylogenetic studies of Carex L.(Cyperaceae)have consistently demonstrated that most subgenera and sections are para-or polyphyletic.Yet,taxonomists continue to use subgenera and sections in Carex classification.Why?The Global Carex Group(GCG)here takes the position that the historical and continued use of subgenera and sections serves to(i)organize our understanding of lineages in Carex,(ii)create an identification mechanism to break the~2000 species of Carex into manageable groups and stimulate its study,and(iii)provide a framework to recognize morphologically diagnosable lineages within Carex.Unfortunately,the current understanding of phylogenetic relationships in Carex is not yet sufficient for a global reclassification of the genus within a Linnean infrageneric(sectional)framework.Rather than leaving Carex classification in its current state,which is misleading and confusing,we here take the intermediate steps of implementing the recently revised subgeneric classification and using a combination of informally named clades and formally named sections to reflect the current state of our knowledge.This hybrid classification framework is presented in an order corresponding to a linear arrangement of the clades on a ladderized phylogeny,largely based on the recent phylogenies published by the GCG.It organizes Carex into six subgenera,which are,in turn,subdivided into 62 formally named Linnean sections plus 49 informal groups.This framework will serve as a roadmap for research on Carex phylogeny,enabling further development of a complete reclassification by presenting relevant morphological and geographical information on clades where possible and standardizing the use of formal sectional names. | Eric H.Roalson Pedro Jiménez-Mejías Andrew L.Hipp Carmen Benítez-Benítez Leo P.Bruederle Kyong-Sook Chung Marcial Escudero Bruce A.Ford Kerry Ford Sebastian Gebauer Berit Gehrke Marlene Hahn Muhammad Qasim Hayat Mathias H.Hoffmann Xiao-Feng Jin Sangtae Kim Isabel Larridon Étienne Léveillé-Bourret Yi-Fei Lu Modesto Luceño Enrique Maguilla Jose IgnacioMárquez-Corro Santiago Martín-Bravo Tomomi Masaki Mónica Míguez Robert F.C.Naczi Anton A.Reznicek Daniel Spalink Julian R.Starr Uzma Tamara Villaverde Marcia J.Waterway Karen L.Wilson and Shu-Ren Zhang | 2021 | Journal of Systematics and Evolution2021，59，4： | 3 |
| 3 | Naming and outline of Dothideomycetes-2014 including proposals for the protection or suppression of generic names显示文摘Article 59.1,of the International Code of Nomenclature for Algae,Fungi,and Plants(ICN;Melbourne Code),which addresses the nomenclature of pleomorphic fungi,became effective from 30 July 2011.Since that date,each fungal species can have one nomenclaturally correct name in a particular classification.All other previously used names for this species will be considered as synonyms.The older generic epithet takes priority over the younger name.Any widely used younger names proposed for use,must comply with Art.57.2 and their usage should be approved by the Nomenclature Committee for Fungi(NCF).In this paper,we list all genera currently accepted by us in Dothideomycetes(belonging to 23 orders and 110 families),including pleomorphic and nonpleomorphic genera.In the case of pleomorphic genera,we follow the rulings of the current ICN and propose single generic names for future usage.The taxonomic placements of 1261 genera are listed as an outline.Protected names and suppressed names for 34 pleomorphic genera are listed separately.Notes and justifications are provided for possible proposed names after the list of genera.Notes are also provided on recent advances in our understanding of asexual and sexual morph linkages in Dothideomycetes.A phylogenetic tree based on four gene analyses supported 23 orders and 75 families,while 35 families still lack molecular data. | Nalin N.Wijayawardene Pedro W.Crous Paul M.Kirk David L.Hawksworth Saranyaphat Boonmee Uwe Braun Dong-Qin Dai Melvina J.D’souza Paul Diederich Asha Dissanayake Mingkhuan Doilom Singang Hongsanan E.B.Gareth Jones Johannes Z.Groenewald Ruvishika Jayawardena James D.Lawrey Jian-Kui Liu Robert Lücking Hugo Madrid Dimuthu S.Manamgoda Lucia Muggia Matthew P.Nelsen Rungtiwa Phookamsak Satinee Suetrong Kazuaki Tanaka Kasun M.Thambugala Dhanushka N.Wanasinghe Saowanee Wikee Ying Zhang Andre Aptroot H.A.Ariyawansa Ali H.Bahkali D.Jayarama Bhat Cécile Gueidan Putarak Chomnunti G.Sybren De Hoog Kerry Knudsen Wen-Jing Li Eric H.C.McKenzie Andrew N.Miller Alan J.L.Phillips Marcin Piatek Huzefa A.Raja Roger S.Shivas Bernad Slippers Joanne E.Taylor Qing Tian Yong Wang Joyce H.C.Woudenberg Lei Cai Walter M.Jaklitsch Kevin D.Hyde | 2014 | Fungal Diversity2014，，6： | 2 |
| 4 | Seismic waves in a stratified half - space 显示文摘 | KENNETT B L N KERRY N J | 1979 | Geophys J R Astron Soc1979，57，： | 1 |
| 5 | Stainless Steel And The Cornea-Staples For Spastic Entropion显示文摘 | Kerry L Ketring | 2005 | The North American Veterinary Conference2005，，： | 1 |
| 6 | High pressure processing of shellfish:A review of microbiological and other quality aspects显示文摘 | MURCHIE L W KERRY J P LINTON M | 2005 | Innovative Food Science and Emerging Technologies2005，，6： | 1 |
| 7 | Facilitation of conditioned fear exinction by systemic administration or intra-amygdala infusions of D-Cycloserine as assessed with fear-potentiated startle in rats显示文摘 | David L Walker Kerry J Ressler Kwak-Tung LU | 2002 | The Journal of Neuroscience2002，22，6： | 1 |
| 8 | Marine natural product as anticancer drugs显示文摘 | Simmons T L Eric A Kerry M | 2005 | Mol Cancer Ther2005，4，2： | 1 |
| 9 | Genistein: Does it prevent or promote breast cancer? 显示文摘 | Kerrie B Bouker Hilakivi-Clarke L | 2000 | Environ Health Perspect2000，108，： | 1 |
| 10 | Seismic waves in a stratified halfspace 显示文摘 | Kennett B L N Kerry N J | 1979 | Geophys J R Astr Soc1979，57，： | 1 |
| 11 | Effects of high-pressure and heat treatments on physical and biochemicalcharacteristics of oysters (Crassostrea gigas)显示文摘 | Cruz-Romero M Kelly A L Kerry J P | 2007 | InnovativeFood Science and Emerging Technologies2007，，8： | 1 |
| 12 | An improved automated immunochemiluminometric third generation hTSH assay for the ACCESS immunoassay system显示文摘 | Danier J Kerry L Peter G | 1996 | Clin Chem1996，42，： | 1 |
| 13 | Fatty acids, volatile compounds and colour changes in high-pressure-treated oysters ( Crassostrea gigas ) 显示文摘 | CRUZ-ROMERO M C KERRY J P KELLY A L | 2008 | Innovat Food Sci Emerg Tech2008，9，1： | 1 |
| 14 | An improved automated immunochem iluminometric third generation hTSH assay for the ACCESS immunoassay system显示文摘 | Danier J Kerry L Peter G | 1996 | Clin Chem1996，42，： | 1 |
| 15 | Fatty acids, volatile compounds and colour changes in high-pressure-treated oysters Innovative显示文摘 | Cruz-Romero M C Kerry J P Kelly A L | 2008 | Innov Food Sci Emerg2008，9，1： | 1 |
| 16 | Nucleation and growth of precipitates in Al-Cu-Mg-Ag alloys显示文摘 | Scott V D Kerry S Trumper R L | 1987 | Materials Science and Technology1987，3，10： | 1 |
| 17 | Synthetic peptides that mimic the binding site of Horseshae crab antipopolysaaccharide factor显示文摘 | Kerry M Paul L | 1994 | J Infect Dis1994，170，11： | 1 |
| 18 | Applied spectroscopy显示文摘 | Mirta G Kerry W Peter L | 2003 | 57(2): 139-1452003，57，2： | 1 |
| 19 | Ascorbic Acid Selectively Improves Large Elastic Artery Compliance in Postmenopausal Women 显示文摘 | Kerrie L Moreau Kathleen M | 2005 | Hypertension2005，45，： | 1 |
| 20 | Effects of highpressure and heat treatments on physical and biochemical characteristics of oysters (Crassostrea gig as)显示文摘 | Cruz-Romero M Kelly A L Kerry J P | 2007 | Innovative Food Science & Emerging Technologies2007，8，1： | 1 |
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