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| 1 | Arterial steroid injection therapy can inhibit the progression of severe acute hepatic failure toward fulminant liver failure显示文摘AIM: To utilize transcatheter arterial steroid injection therapy (TASIT) via the hepatic artery to reduce hepatic macrophage activity in patients with severe acute hepatic failure.METHODS: Thirty-four patients with severe acute hepatic failure were admitted to our hospital between June 2002 to June 2006 providing for the possibility of liver transplantation (LT). Seventeen patients were treated using traditional liver supportive procedures, and the other 17 patients additionally underwent TASIT with 1000 mg methylprednisolone per day for 3 continuous days. RESULTS: Of the 17 patients who received TASIT, 13 were cured without any complications, 2 died, and 2 underwent LT. Of the 17 patients who did not receive TASIT, 4 were self-limiting, 7 died, and 6 underwent LT. Univariate logistic analysis revealed that ascites, serum albumin, prothrombin time, platelet count, and TASIT were significant variables for predicating the prognosis. Multivariate logistic regression analysis using stepwise variable selection showed that prothrombin time, platelet count, and TASIT were independent predictive factors. CONCLUSION: TASIT might effectively prevent the progression of severe acute hepatic failure to a fatal stage of fulminant liver failure. | Kazuhiro Kotoh Munechika Enjoji Makoto Nakamuta Tsuyoshi Yoshimoto Motoyuki Kohjima Shusuke Morizono Shinsaku Yamashita Yuki Horikawa Kengo Yoshimitsu Tsuyoshi Tajima Yoshiki Asayama Kousei Ishigami Masakazu Hirakawa | 2006 | World Journal of Gastroenterology2006,12,41: | 13 |
| 2 | Imaging pitfalls of pancreatic serous cystic neoplasm and its potential mimickers显示文摘The aim of this article is to clarify diagnostic pitfalls of pancreatic serous cystic neoplasm(SCN) that may result in erroneous characterization. Usual and unusual imaging findings of SCN as well as potential SCN mimickers are presented. The diagnostic key of SCN is to look for a cluster of microcysts(honeycomb pattern), which may not be always found in the center. Fibrosis in SCN may be mistaken for a mural nodule of intraductal papillary mucinous neoplasm(IPMN). The absence of cyst wall enhancement may be helpful to distinguish SCN from mucinous cystic neoplasm. However, oligocystic SCN and branch duct type IPMN may morphologically overlap. In addition, solid serous adenoma, an extremely rare variant of SCN, is difficult to distinguish from neuroendocrine tumor. | Kousei Ishigami Akihiro Nishie Yoshiki Asayama Yasuhiro Ushijima Yukihisa Takayama Nobuhiro Fujita Shunichi Takahata Takao Ohtsuka Tetsuhide Ito Hisato Igarashi Shuji Ikari Catherine M Metz Hiroshi Honda | 2014 | World Journal of Radiology2014,6,3: | 6 |
| 3 | Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer显示文摘 | Hiroshi Kurahara Hiroyuki Shinchi Yuko Mataki Kousei Maemura Hidetoshi Noma Fumitake Kubo Masahiko Sakoda Shinichi Ueno Shoji Natsugoe Sonshin Takao | 2011 | Journal of Surgical Research2011,,2: | 3 |
| 4 | Image quality and diagnostic performance of free-breathing diffusion-weighted imaging for hepatocellular carcinoma显示文摘AIM To retrospectively evaluate the diagnostic performance of free-breathing diffusion-weighted imaging(FB-DWI) with modified imaging parameter settings for detecting hepatocellular carcinomas(HCCs).METHODS Fifty-one patients at risk for HCC were scanned with both FB-DWI and respiratory-triggered DWI with the navigator echo respiratory-triggering technique(RTDWI).Qualitatively,the sharpness of the liver contour,the image noise and the chemical shift artifacts on each DWI with b-values of 1000 s/mm2 were independently evaluated by three radiologists using 4-point scoring.Wecompared the image quality scores of each observer between the two DWI methods,using the Wilcoxon signed-rank test.Quantitatively,we compared the signal-to-noise ratios(SNRs) of the liver parenchyma and lesion-to-nonlesion contrast-to-noise ratios(CNRs) after measuring the signal intensity on each DWI with a b-factor of 1000 s/mm2.The average SNRs and CNRs between the two DWI methods were compared by the paired t-test.The detectability of HCC on each DWI was also analyzed by three radiologists.The detectability provided by the two DWI methods was compared using Mc Nemar's test.RESULTS For all observers,the averaged image quality scores of FB-DWI were:Sharpness of the liver contour [observer(Obs)-1,3.08 ± 0.81;Obs-2,2.98 ± 0.73;Obs-3,3.54 ± 0.75],those of the distortion(Obs-1,2.94 ± 0.50;Obs-2,2.71 ± 0.70;Obs-3,3.27 ± 0.53),and the chemical shift artifacts(Obs-1,3.38 ± 0.60;Obs-2,3.15 ± 1.07;Obs-3,3.21 ± 0.85).The averaged image quality scores of RTDWI were:Sharpness of the liver contour(Obs-1,2.33 ± 0.65;Obs-2,2.37 ± 0.74;Obs-3,2.75 ± 0.81),distortion(Obs-1,2.81 ± 0.56;Obs-2,2.25 ± 0.74;Obs-3,2.96 ± 0.71),and the chemical shift artifacts(Obs-1,2.92 ± 0.59;Obs-2,2.21 ± 0.85;Obs-3,2.77 ± 1.08).All image quality scores of FB-DWI were significantly higher than those of RT-DWI(P < 0.05).The average SNR of the normal liver parenchyma by FB-DWI(11.0 ± 4.8) was not significantly different from that shown by RT-DWI(11.0 ± 5.0);nor were the lesion-to-nonlesion CNRs significantly different(FB-DWI,21.4 ± 17.7;RT-DWI,20.1 ± 15.1).For all three observers,the detectability of FB-DWI(Obs-1,43.6%;Obs-2,53.6%;and Obs-3,45.0%) was significantly higher than that of RT-DWI(Obs-1,29.1%;Obs-2,43.6%;and Obs-3,34.5%)(P < 0.05).CONCLUSION FB-DWI showed better image quality and higher detectability of HCC compared to RT-DWI,without significantly reducing the SNRs of the liver parenchyma and lesionto-nonlesion CNRs. | Yukihisa Takayama Akihiro Nishie Yoshiki Asayama Kousei Ishigami Daisuke Kakihara Yasuhiro Ushijima Nobuhiro Fujita Ken Shirabe Atsushi Takemura Hiroshi Honda | 2017 | World Journal of Hepatology2017,9,14: | 3 |
| 5 | Intraductal Papillary Mucinous Neoplasms of the Pancreas With Distinct Pancreatic Ductal Adenocarcinomas Are Frequently of Gastric Subtype显示文摘 | Noboru Ideno Takao Ohtsuka Hiroshi Kono Kenji Fujiwara Yasunori Oda Shinichi Aishima Tetsuhide Ito Kousei Ishigami Shoji Tokunaga Kenoki Ohuchida Shunichi Takahata Masafumi Nakamura Kazuhiro Mizumoto Masao Tanaka | 2013 | Annals of Surgery2013,,1: | 2 |
| 6 | 在 transcatheter 以后的征兆的 arterioportal 管的临床的结果动脉的 embolization显示文摘 AIM: To evaluate the complications and clinical outcomes of transcatheter arterial embolization (TAE) for symptoms related to severe arterioportal fistulas (APFs). METHODS: Six patients (3 males, 3 females; mean age, 63.8 years; age range, 60-71 years) with chronic liver disease and severe APFs due to percutaneous intrahepatic treatment (n=5) and portal vein (PV) tumor thrombosis of hepatocellular carcinoma (n=1) underwent TAE for symptoms related to severe APFs [refractory ascites (n=4), hemorrhoidal hemorrhage (n=1), and hepatic encephalopathy (n=1)]. Control of symptoms related to APFs and complications were evaluated during the follow-up period (range, 4-57 mo). RESULTS: In all patients, celiac angiography revealed immediate retrograde visualization of the main PV before TAE, indicating severe APF. Selective TAE for the hepatic arteries was performed using metallic coils (MC, n=4) and both MCs and n-butyl cyanoacrylate (n=2). Three patients underwent repeated TAEs for residual APFs and ascites. Four patients developed PV thrombosis after TAE. During the follow-up period after TAE, APF obliteration and symptomatic improvement were obtained in all patients. CONCLUSION: Although TAE for severe APFs may sometimes be complicated by PV thrombosis, TAE can be an effective treatment to improve clinical symptoms related to severe APFs. | Masakazu Hirakawa Akihiro Nishie Yoshiki Asayama Kousei Ishigami Yasuhiro Ushijima Nobuhiro Fujita Hiroshi Honda | 2013 | World Journal of Radiology2013,5,2: | 2 |
| 7 | 用于双层BD光盘的新型单光束循迹方法 | Kousei Sano 叶娜 | 2007 | 记录媒体技术2007,0,4: | 1 |
| 8 | Phase Separation Structure in the Polymer Blend of Fluorocarbon Elastomer and Hydrogenated Nitrile Rubber显示文摘 | Kousei Hirano | 2005 | Journal of Applied Polymer Science2005,95,: | 1 |
| 9 | Apical/Basolateral Surface Expression of Drug Transporters and its Role in Vectorial Drug Transport显示文摘 | Kousei Ito Hiroshi Suzuki Toshiharu Horie Yuichi Sugiyama | 2005 | Pharmaceutical Research2005,,10: | 1 |
| 10 | Coil embolization of arterioportal fistula that developed after partial gastrectomy显示文摘 | Kousei Ishigami Kengo Yoshimitsu Hiroshi Honda Toshiro Kuroiwa Hiroyuki Irie Hitoshi Aibe Tsuyoshi Tajima Makoto Hashizume Kouji Masuda | 1999 | CardioVascular and Interventional Radiology1999,,4: | 1 |
| 11 | Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump显示文摘 | Hidetaka Akita Hiroshi Suzuki Kousei Ito Setsuo Kinoshita Norihito Sato Hajime Takikawa Yuichi Sugiyama | 2001 | BBA - Biomembranes2001,,1: | 1 |
| 12 | Biodistribution of humanized anti-VEGF monoclonal antibody/bevacizumab on peritoneal metastatic models with subcutaneous xenograft of gastric cancer in mice显示文摘 | Yasumichi Yagi Sachio Fushida Shinichi Harada Tomoya Tsukada Jun Kinoshita Katsunobu Oyama Hideto Fujita Itasu Ninomiya Takashi Fujimura Masato Kayahara Seigo Kinuya Masakazu Yashiro Kousei Hirakawa Tetsuo Ohta | 2010 | Cancer Chemotherapy and Pharmacology2010,,4: | 1 |
| 13 | Impact of vascular endothelial growth factor-C and -D expression in human pancreatic cancer: its relationship to lymph node metastasis 显示文摘 | Hiroshi Kurahara Sonshin Takao Kousei Maemura EA | 2004 | Clin Cancer Res2004,10,24: | 1 |
| 14 | Preoperative and Postoperative Magnetic Resonance Image Evaluations of the Spinal Cord in Cervical Myelopathy显示文摘 | Kazunori Yone Takashi Sakou Mitsuhiro Yanase Kousei Ljiri | 1992 | Spine (S Suppl)1992,,10: | 1 |
| 15 | Ruptured splenic abscess: a cause of pneumoperitoneum in a patient with AIDS显示文摘 | Kousei Ishigami Gerald T. Decker Jody A. Bolton-Smith Isaac Samuel Scott R. Wilson Bruce P. Brown | 2003 | Emergency Radiology2003,,3: | 1 |
| 16 | Impact of vascular endothelial growth factor-C and-D expression in human pancreatic cancer:Its relationship to lymph node metastasis显示文摘 | Hiroshi K Sonshin T Kousei M | 2004 | Clin Cancer Res2004,10,15: | 1 |
| 17 | Three Cases of Serous Oligocystic Adenomas of the Pancreas; Evaluation of Cyst Wall Thickness for Preoperative Differentiation from Mucinous Cystic Neoplasms显示文摘 | Hiroshi Yamaguchi Kousei Ishigami Takahiro Inoue Takashi Eguchi Shigenori Nagata Yosuke Kuroda Yunosuke Nishihara Koji Yamaguchi Masao Tanaka Masazumi Tsuneyoshi | 2008 | Journal of Gastrointestinal Cancer2008,,1: | 1 |
| 18 | Quantitative analysis of liver function using superparamagnetic iron oxide- and Gd-EOB-DTPA-enhanced MRI: Comparison with Technetium-99m galactosyl serum albumin scintigraphy显示文摘 | Akihiro Nishie Yasuhiro Ushijima Tsuyoshi Tajima Yoshiki Asayama Kousei Ishigami Daisuke Kakihara Tomohiro Nakayama Yukihisa Takayama Daisuke Okamoto Koichiro Abe Makoto Obara Kengo Yoshimitsu Hiroshi Honda | 2011 | European Journal of Radiology2011,,6: | 1 |
| 19 | Indication for preoperative localization of small peripheral pulmonary nodules in thoracoscopic surgery显示文摘 | Hajime Saito Yoshihiro Minamiya Ikuo Matsuzaki Kasumi Tozawa Kousei Taguchi Taku Nakagawa Manabu Hashimoto Yoshinori Hirano Jun-ichi Ogawa | 2002 | The Journal of Thoracic and Cardiovascular Surgery2002,,6: | 1 |
| 20 | Impact of vascular endothelial growth factor-C and -D expression in human pancreatic cancer:Its relationship to lymph node metastasis显示文摘 | Hiroshi K Sonshin T Kousei M | 2004 | Clin Can Res2004,10,15: | 1 |