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| 1 | 重复经颅磁刺激治疗抑郁症的机制研究进展(英文)显示文摘概述:抑郁障碍是目前最常见的心理健康问题之一。然而,对于该疾病的基于机制的治疗方法仍然是难以捉摸的。重复经颅磁刺激(rTMS)是一种非侵入性的程序,它可以以一种脉冲磁场来刺激大脑中的电活动,被认为是一种有效的抑郁症治疗方式。在这里,我们回顾了关于rTMS治疗抑郁症的临床和基础研究的主要发现,包括它的抗抑郁疗效,基本原理,调节神经回路、神经递质和脑网络、海马神经发生、和突出的功效,以及分子通路。 | Zhengwu PENG Cuihong ZHOU Shanshan XUE Jie BAI Shoufen YU Xiaosa LI Huaning WANG Qingrong TAN | 2018 | 上海精神医学2018，30，2： | 13 |
| 2 | Downregulation of serum mi R-17 and mi R-106b levels in gastric cancer and benign gastric diseases显示文摘Altered micro RNA(mi RNA) associated with gastric cancer(GC) development and mi R-17 and mi R-106 b were differentially expressed in GC tissues. This study detected serum levels of mi R-17 and mi R-106 b expression in GC, benign gastric disease(BGD) and healthy controls to assess them as tumor markers for GC. Serum samples from 40 GC, 32 BGD(10 gastric ulcer, 14 gastric polyps, and 8 gastric ulcer with polyps) and 36 healthy individuals were subjected to quantitative reverse transcription polymerase chain reaction(q RT-PCR) analysis of mi R-17 and mi R-106 b expression. The data showed that the serum levels of mi R-17 and mi R-106 b were significantly reduced in healthy individuals and BGD patients compared to GC patients. There was a significant association of mi R-17 and mi R-106 b expression with age, but not with other clinicopathological features, such as gender, tumor differentiation, stage and lymphatic metastasis. Further analysis showed that, in discriminating GC patients from healthy controls, mi R-17 could yield a receiver-operating characteristic(ROC) area under the curve(AUC) of 0.879 with 80.6% sensitivity and 87.5% specificity and mi R-106 b could yield an AUC of 0.856 with 75.0% sensitivity and 92.5% specificity. The combined AUC of mi R-17 and mi R-106 b was 0.913 with 83.3% sensitivity and 87.5% specificity. Collectively, these data suggest that detection of serum mi R-17 and mi R-106 b levels should be further evaluated as novel non-invasive biomarkers in early GC detection and surveillance of disease progression. | Qinghai Zeng Cuihong Jin Wenhang Chen Fang Xia Qi Wang Fan Fan Juan Du Yihang Guo Changwei Lin Kaiyan Yang Jingjing Li Xiaowei Peng Xiaorong Li Ke Cao | 2014 | Chinese Journal of Cancer Research2014，26，6： | 12 |
| 3 | Application of chemical fractionation and X-ray powder diffraction to study phosphorus speciation in sediments from Lake Hongfeng,China显示文摘Based on the techniques of sequential extraction and X-ray powder diffraction(XRD) ,the distribution characteristics of phosphorus speciation were investigated in 13 sediment samples from Lake Hongfeng,an important drinking water source for Guiyang with a typical karstic limestone environment.The total phosphorus(TP) concentrations in the sediments ranged from 973.36 to 2334.18 mg/kg with a mean concentration of 1635.87 mg/kg(dry weight) ,and it was evident that the phosphorus level in the sediments was high compared with other eutrophic lakes such as Lake Chaohu and Lake Xihu.The results of the two methods,sequential extraction and XRD,demonstrated the presence of different phosphorus species in the lake sediments.Being compatible with local geophysical characteristics,the results of sequential extraction techniques indicate that the average percentages of dissolved phosphorus(DP) ,aluminum-bound phosphorus(Al-P) ,iron-bound phosphorus(Fe-P) ,calcium-bound phosphorus(Ca-P) and organic phosphorus(OP) in the sediments were 0.40%,7.06%,5.07%,45.48%and 38.49%,respectively.Notably,the concentrations of inorganic phosphorus(IP) were higher than those of OP,and the IP consisted primarily of Ca-P.The high concentrations of Ca-P may temporarily control the release of phosphorus from the sediments because it is a relatively stable,inert and non-bioavailable phosphorus fraction.The results of XRD analysis indicated that,among phosphorus species,AlPO4 was found in all sediment samples at relatively high concentrations.Moreover,the TP concentrations in the sediments were high;thus the release potential and bioavailability of phosphorus in the sediments was important.Further statistical analyses of the results revealed significant correlations between phosphorus species in the sediments with two extractable principal components and four selectable cluster levels allowing interpretation of possible origins of phosphorus loading and transformation mechanisms of phosphorus species.Furthermore,available remediation measures were briefly assessed for the lake while considering its distinct environmental features. | JIANG CuiHong WU Di HU JiWei LIU Feng HUANG XianFei LI CunXiong JIN Mei | 2011 | Chinese Science Bulletin2011，56，20： | 9 |
| 4 | Predictions of mortality related to four major cancers in China,2020 to 2030显示文摘Background:Cancer has become a global health problem,and assessments of cancer mortality are important for effective public health policy-making and adequate resource allocation.In this study,we aimed to predict the mortality rates and numbers of deaths related to four common cancers(lung,liver,stomach,and esophagus)in China from 2020 to 2030 and to estimate the corresponding cancer burden caused by population aging and tobacco smoking.Methods:Cancer mortality data(2004-2017)were extracted from China’s death surveillance datasets,and China’s population figures(2020-2030)were obtained from the United Nations population projections.Smoking prevalence data were retrieved from a World Health Organization global report,and relative risks of smoking and cancers were derived from large-scale Asian studies.We predicted the deaths related to the four major cancers and age-standardized mortality rates using joinpoint regression and linear regression models.The tobacco smoking related burden of these four major cancers was estimated using the population attributable fraction.Results:Unlike lung cancer mortality which was predicted to continue to increase,the age-standardized mortality rates for digestive cancers(liver,stomach,and esophageal cancers)are predicted to decline over the next decade.The number of deaths caused by the four major cancers is predicted to increase from 1,490,304 in 2020 to 1,823,960 in 2030.The age-specific mortality rates of the four major cancers are predicted to increase with age after 40-45 years,peaking in the age groups of 80-84 and ≥85 years.In 2030,the combined number of deaths from the four examined cancers among adults aged ≥65 years is predicted to be 1,167,153,accounting for 64% of all deaths from these cancers.Tobacco smoking is predicted to contribute to nearly 29% of deaths fromthese cancers,corresponding to 527,577 deaths.Conclusions:The overall trend in the combined total mortality from four major cancers is predicted to decline over the next decade;however,the corresponding death toll is expected to surge,in the context of China’s population aging and high smoking prevalence.These estimates provide data-driven evidence for China to implement effective cancer control measures in the future. | Ning Li Peng Wu Yubing Shen Cuihong Yang Luwen Zhang Yali Chen Zixing Wang Jingmei Jiang | 2021 | Cancer Communications2021，41，5： | 4 |
| 5 | Changes of visceral properties and digestive enzymes in the herbivorous marine teleost Siganus canaliculatus fed on different diets显示文摘The rabbitfish Siganus canaliculatus is one of the few cultured herbivorous marine teleosts. To better understand the digestive physiology of this fish and provide data for designing formulated feed using macroalgae as an ingredient, the changes of visceral properties and digestive enzyme activities were investigated after the juveniles were fed on different types of food including raw fish(RF), formulated diet(FD) or macroalgae Enteromorpha prolifra(EP) and Gracilaria lemaneiformis(GL) for eight weeks. The results showed that the hepatosomatic and viscerosomatic indices in the RF and FD groups, as well as the relative intestine length(RIL) in the EP and GL groups, were significantly higher than those in other groups. Additionally, differences in the histological structure of the liver and anterior intestine were also observed among different dietary groups. The hepatic nuclei were displaced to the periphery by lipid inclusions in fish fed RF. The highest levels of mucosal folds were found in the anterior intestines of fish fed macroalgae. Digestive enzyme activity profiles showed obvious fluctuations in the first three weeks, and then leveled off in the following weeks. The levels of protease, lipase and α-amylase in the alimentary tract showed changes related to the levels of dietary protein, lipid and carbohydrate, respectively.Although macroalgae significantly inhibited the activity of protease in the stomach, it increased RIL and the number of mucosal folds in the anterior intestine so as to compensate for the influences on protease activities in the stomach. This study suggests that the digestive tract of rabbitfish can well adapt to different diets, and needs about three weeks to physiologically acclimatize to the nutritional status, thus implying that rabbitfish are somewhat omnivorous. | XIE Dizhi XU Shude WU Qingyang CHEN Fang WANG Shuqi YOU Cuihong LI Yuanyou | 2018 | Acta Oceanologica Sinica2018，37，2： | 3 |
| 6 | Switching emissions of two tetraphenylethene derivatives with solvent vapor, mechanical, and thermal stimuli显示文摘Two derivatives of tetraphenylethene (TPE) were synthesized through one step cross McMurry coupling reaction. Both luminogens exhibit aggregation-induced emission (AIE) and crystallization induced emission enhancement (CIEE). The emissions of both luminogens could be switched between blue and green through reversible modulation of morphology with thermal, organic solvent fuming and mechanical stimuli. Thus we provide a possible design strategy for emission switching materials. | SHI JunQing ZHAO WeiJun LI CuiHong LIU ZhengPing BO ZhiShan DONG YuPing DONG YongQiang TANG Ben Zhong | 2013 | Chinese Science Bulletin2013，58，22： | 2 |
| 7 | Ecotoxicological effects of polycyclic musks and cadmium on seed germination and seedling growth of wheat(Triticum aestivum)显示文摘Single and joint toxic effects of polycyclic musks including 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2benzopyran (HHCB) and 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronapthalene (AHTN) and cadmium (Cd) on seed germination and seedling growth of wheat (Triticum aestivum) were investigated.The results showed that the toxicity sequence of HHCB toxic to wheat seed germination and seedling growth was similar to that of AHTN,that is,germination rate > shoot elongation > root elongation,while the toxicity of Cd was in the sequence of root elongation > shoot elongation > germination rate,according to the LC50 and EC50 values.It is suggested that polycyclic musks and Cd had different toxicological mechanisms.Root and shoot elongation of wheat might be good bioindicators for the contamination of polycyclic musks and Cd in soil.The mixture of polycyclic musks and Cd had synergistic effects on T.aestivum according to the equi-toxic mixture approach when root elongation was selected as the toxicological endpoint.Thus,the joint toxicity of HHCB and Cd was significantly higher than the single toxicity of HHCB or Cd,which was also confirmed by the EC50 mix value of the mixture (EC50 mix=0.530 TU mix).The EC50 mix value of the mixture of AHTN and Cd was 0.614 TU mix,which indicated that the mixture toxicity was strengthened when AHTN coexisted with Cd. | Cuihong Chen Qixing Zhou Yanyu Bao Yaning Li Ping Wang | 2010 | Journal of Environmental Sciences2010，22，12： | 2 |
| 8 | The receptor-like cytosolic kinase RIPK activates NADP-malic enzyme 2 to generate NADPH for fueling ROS production显示文摘Reactive oxygen species(ROS)production is a conserved immune response in Arabidopsis primarily medi-ated by respiratory burst oxidase homolog D(RBOHD),a nicotinamide adenine dinucleotide phosphate(NADPH)oxidase associated with the plasma membrane.A rapid increase in NADPH is necessary to fuel RBOHD proteins and thus maintain ROS production.However,the molecular mechanism by which NADPH is generated to fuel RBOHD remains unclear.In this study,we isolated a new mutant allele of FLAGELLIN-INSENSITIVE 4(FIN4),which encodes the first enzyme in de novo NAD biosynthesis.fin4 mu-tants show reduced NADPH levels and impaired ROS production.However,FIN4 and other genes involved in NAD-and NADPH-generating pathways are not highly upregulated upon elicitor treatment,raising a pos-sibility that a cytosolic NADP-linked dehydrogenase might be post-transcriptionally activated to maintain the NADPH supply close to RBOHD.To verify this possibility,we isolated the proteins associated with RPM1-INDUCED PROTEIN KINASE(RIPK),a receptor-like cytoplasmic kinase that regulates broad-spectrum ROS signaling in plant immunity,and identified NADP-malic enzyme 2(NADP-ME2),an NADPH-generating enzyme.Compared with wild-type plants,nadp-me2 mutants display decreased NADP-ME activity,lower NADPH levels,and reduced ROS production in response to immune elicitors.Furthermore,we found that RIPK can directly phosphorylate NADP-ME2 and enhance its activity in vitro.The phosphorylation of the NADP-ME2 S371 residue contributes to ROS production upon immune elicitor treatment and susceptibility to the necrotrophic bacterium Pectobacterium carotovorum.Collectively,our study suggests that RIPK phosphorylates and activates NADP-ME2 to rapidly increase cytosolic NADPH,thus fueling RBOHD to sustain ROS production in plant immunity. | Binyan Wu Ping Li Xiufang Hong Cuihong Xu Ran Wang Yan Liang | 2022 | Molecular Plant2022，15，5： | 2 |
| 9 | Preference of the Herbivorous Marine Teleost Siganus canaliculatus for Different Macroalgae显示文摘The decomposition of a large amount of unexploited macroalgal resource along the coast of China often results in heavy environmental pollution. In order to pave a way of using macroalgae as the dietary ingredient of rabbitfish Siganus canaliculatus, one of a few farmed herbivorous marine teleosts in China, its preference(feeding selectivity) for different macroalgae was determined in this study. Seven seaweed species abundantly inhabiting the coast of east Guangdong Province were exposed simultaneously to rabbitfish juveniles in laboratory(multiple-choice feeding) with their content and absolute intake assayed. It was found that the most preferred algae were Ulva prolifera, Gracilaria lemaneiformis and Chaetomorpha linum, less preferred algae were U. pertusa and Porphyra haitanensis, and least preferred ones were Sargassum fusiforme and Corallina sessilis. Such an order did not change when one to four relatively preferred seaweeds were removed. The preferred seaweeds were richer in protein and soluble sugar thus higher in energy than the least preferred. In addition, this fish was found to favor filamentous and flat algae rather than calcified ones. Accordingly, the richness of nutrients and morphological characteristics determined the preference of S. canaliculatus for tested macroalgae. | YOU Cuihong ZENG Fangui WANG Shuqi LI Yuanyou | 2014 | Journal of Ocean University of China2014，13，3： | 2 |
| 10 | Friction Stir Welding of Zr_(55)Al_(10)Ni_5Cu_(30) Bulk Metallic Glass to Crystalline Aluminum显示文摘The Zr55Al10Ni5Cu30 bulk metallic glass plate were successfully welded to crystalline aluminum plates by using a friction stir welding (FSW) method. The welded zone was examined. No defects, cracks or pores were observed and no other crystalline phases except for aluminum were found in the welded joint. The strength of the joint is higher than that of aluminum. The glassy phase in the stir zone keeps the amorphous state, showing a successful welding. The storage modulus softens over the glass transition. And the weldability was discussed according to this phenomena. | Zuoxiang Qin Cuihong Li Haifeng Zhang Zhongguang Wang Zhuangqi Hu Zhiqiang Liu | 2009 | Journal of Materials Science & Technology2009，25，6： | 2 |
| 11 | Morbidity Analysis of the Notifiable Infectious Diseases in China,2018显示文摘Introduction Notifiable infectious disease surveillance is important for understanding the trends in morbidity for certain diseases,especially detection of acute infectious disease outbreaks and changing epidemiology.A web-based reporting system was deployed in January 2004,which has improved data collection and speed tremendously.This report provides an updated analysis for reports published in 2013 and 2015.Methods Data from the National Notifiable Disease Reporting System(NNDRS)was used.The NNRDS shows data from 39 notifiable diseases split into three categories(A,B,and C)based on severity and importance.A descriptive analysis was conducted to analyze the morbidity of notifiable diseases in China.Results In 2018,the morbidity of national notifiable diseases was 559.41 per 100,000 population,an increase of 12.88% compared with the average of 2015–2017.The proportion of laboratory confirmed cases was 36.22%,which decreased 4.03% compared with the average of that in the recent three years.Diseases transmitted by direct contact/fecal–oral transmission accounted for the largest proportion,49.37% of the total reported cases,followed by the respiratory transmitted diseases,blood-borne/sexually transmitted diseases,and the zoonotic and vectorborne diseases with a proportion of 25.18%,24.60%,and 0.85%,respectively.Pathogenic descriptive analysis showed that the viral-infected cases accounted for 73.78% of the totals,followed by the bacterialinfected and parasitic diseases.Conclusion The national morbidity of notifiable infectious diseases showed increases in 2018,mostly due to higher morbidity of category C diseases,such as HFMD,infectious diarrhea,and influenza,and these diseases need to be further prioritized in disease control and prevention efforts.Laboratory confirmed cases remain low and need to be improved to improve data quality. | Shuaibing Dong Xiang Ren Cuihong Zhang Mengjie Geng Yuliang Zhu Lusha Shi Lijie Zhang Zhongjie Li Liping Wang | 2019 | China CDC weekly2019，1，4： | 2 |
| 12 | Efficient multi-attribute negotiation with incomplete information显示文摘 | Lai Guoming Li Cuihong Sycara K | 2006 | Group Decision and Negotiation2006，15，5： | 1 |
| 13 | Bilateral negotiation decisions with uncertain dynamic outside options 显示文摘 | LI Cuihong GIAMPAPA J SYCARA K | 2006 | IEEE Transactions on Systems Man and Cybernetics Part C2006，36，1： | 1 |
| 14 | Yoctonewton force detection based on optically levitated oscillator显示文摘Optically levitated oscillators in high vacuum have excellent environmental isolation and low mass compared with conventional solid-state sensors,which makes them suitable for ultrasensitive force detection.The force resolution usually scales with the measurement bandwidth,which represents the ultimate detection capability of the system under ideal conditions if sufficient time is provided for measurement.However,considering the stability of a real system,a method based on the Allan variance is more reliable to evaluate the actual force detection performance.In this study,a levitated optomechanical system with a force detection sensitivity of 6.33±1.62 zN/Hz^(1/2)was demonstrated.And for the first time,the Allan variance was introduced to evaluate the system stability due to the force sensitivity fluctuations.The force detection resolution of 166.40±55.48 yN was reached at the optimal measurement time of 2751 s.The system demonstrated in this work has the best force detection performance in both sensitivity and resolution that have been reported so far for optically levitated particles.The reported high-sensitivity force detection system is an excellent candidate for the exploration of new physics such as fifth force searching,high-frequency gravitational waves detection,dark matter research and so on. | Tao Liang Shaochong Zhu Peitong He Zhiming Chen Yingying Wang Cuihong Li Zhenhai Fu Xiaowen Gao Xinfan Chen Nan Li Qi Zhu Huizhu Hu | 2023 | Fundamental Research2023，3，1： | 1 |
| 15 | Efficient muhi-attribute negotiation with incomplete information显示文摘 | Lai Guoming Li Cuihong Sycara K | 2006 | Group Decisionand Negotiation2006，15，5： | 1 |
| 16 | High-Sensitivity Matrix-Assisted Laser Desorption/Ionization Fourier Transform Mass Spectrometry Analyses of Small Carbohydrates and Amino Acids Using Oxidized Carbon Nanotubes Prepared by Chemical Vapor Deposition as Matrix显示文摘 | Wang Cuihong Li Jian Yao Shengjun | 2007 | Analytica Chimica Acta2007，604，2： | 1 |
| 17 | A plartar copoly- mer for high efficiency polymer solar cells显示文摘 | Qjn Ruiping Li Weiwei Li Cuihong | 2009 | J Am Chem Soc2009，131，14： | 1 |
| 18 | Spirobifluorene- Based Conjugated Polymers for Polymer Solar Cells withHigh Open-Circuit Voltage 显示文摘 | Wang Ming Li Cuihong Lv Aifeng | 2012 | Macromol2012，45，7： | 1 |
| 19 | High performance composite membranes with a polycarbophil calcium transition layer for pervaporation dehydration of ethanol显示文摘 | Cuihong Zhao Hong Wu Xianshi Li Fusheng Pan Yifan Li Jing Zhao Zhongyi Jiang Peng Zhang Xingzhong Cao Baoyi Wang | 2013 | Journal of Membrane Science2013，，： | 1 |
| 20 | Effects of population aging on the mortality burden of related cancers in urban and rural areas of China, 2004–2017: a population-based study显示文摘Objective:China is a developing country with urban–rural disparities and accelerating population aging.Therefore,quantifying the effects of population aging on the cancer mortality burden is urgently needed.Methods:Using data from China’s death surveillance datasets(2004–2017),we decomposed and quantified the effects of population aging and factor variations on cancer mortality rates in urban and rural China during 2004–2017 through a decomposition method.R ratios were used to assess the extent of the mortality decreases attributable to factor variations offsetting the increases attributable to population aging for 4 aging-related cancers(lung,colorectal,esophageal,and stomach cancer).Results:Overall,population aging has led to continued increases in cancer mortality rates in China during 2004–2017(mortality rates attributable to population aging:8.63/100,000 for urban men,4.21/100,000 for urban women,11.95/100,000 for rural men,and 5.66/100,000 for rural women).The 4 cancers displayed 3 patterns.The mortality rates from lung cancer in rural China and from colorectal cancer nationwide increased because of both population aging and factor variations.Population aging was primarily responsible for the growing mortality due to lung cancer in urban areas.However,for esophageal and stomach cancer,the effect of population aging was not dominant,thus resulting in decreases in mortality rates.Conclusions:Health resource allocation should prioritize areas or cancers more adversely affected by population aging.The burden of cancer will continue to increase in the future,because of rapid population aging,but can still be offset or even reversed with enhanced cancer control and prevention. | Yali Chen Cuihong Yang Ning Li Zixing Wang Peng Wu Jin Du Jingmei Jiang | 2022 | Cancer Biology & Medicine2022，19，5： | 1 |
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