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| 1 | Dissection of two quantitative trait loci for grain weight linked in repulsion on the long arm of chromosome 1 of rice(Oryza sativa L.)显示文摘Grain weight is a key determinant of grain yield in rice. Three sets of rice populations with overlapping segregating regions in isogenic backgrounds were established in the generations of BC2 F5, BC2 F6 and BC2 F7, derived from Zhenshan 97 and Milyang 46, and used for dissection of quantitative trait loci(QTL) for grain weight. Two QTL linked in repulsion phase on the long arm of chromosome 1 were separated. One was located between simple sequence repeat(SSR) markers RM11437 and RM11615, having a smaller additive effect with the enhancing allele from the maintainer line Zhenshan 97 and a partially dominant effect for increasing grain weight. The other was located between SSR markers RM11615 and RM11800, having a larger additive effect with the enhancing allele from the restorer line Milyang 46 and a partially dominant effect for increasing grain weight. When the two QTL segregated simultaneously, a residual additive effect with the enhancing allele from Milyang 46 and an over-dominance effect for increasing grain weight were detected. This suggests that dominant QTL linked in repulsion phase might play an important role in heterosis in rice. Our study also indicates that the use of populations with overlapping segregating regions in isogenic backgrounds is helpful for the dissection of minor linked QTL. | Liang Guo Kai Wang Junyu Chen Derun Huang Yeyang Fan Jieyun Zhuang | 2013 | The Crop Journal2013，1，1： | 6 |
| 2 | m6A RNA methylation-mediated HNF3γreduction renders hepatocellular carcinoma dedifferentiation and sorafenib resistance显示文摘Hepatocyte nuclear factor 3γ(HNF3γ)is a hepatocyte nuclear factor,but its role and clinical significance in hepatocellular carcinoma(HCC)remain unclear.Herein,we report that HNF3γexpression is downregulated in patient HCC and inversely correlated with HCC malignancy and patient survival.Moreover,our data suggested that the HNF3γreduction in HCC could be mediated by METTL14-dependent m6A methylation of HNF3γmRNA.HNF3γexpression was increased during hepatic differentiation and decreased in dedifferentiated HCC cells.Interestingly,HNF3γdelivery promoted differentiation of not only HCC cells but also liver CSCs,which led to suppression of HCC growth.Mechanistic analysis suggested an HNF3γ-centered regulatory network that includes essential liver differentiation-associated transcription factors and functional molecules,which could synergistically facilitate HCC cell differentiation.More importantly,enforced HNF3γexpression sensitized HCC cells to sorafenib-induced growth inhibition and cell apoptosis through transactivation of OATP1B1 and OATP1B3 expression,which are major membrane transporters for sorafenib uptake.Clinical investigation showed that patient-derived HCC xenografts with high HNF3γexpression exhibited a sorafenib response and patients with high HCC HNF3γlevels benefited from sorafenib therapy.Together,these results suggest that HNF3γplays an essential role in HCC differentiation and may serve as a therapeutic target and predictor of sorafenib benefit in patients. | Tengfei Zhou Shichao Li Daimin Xiang Junyu Liu Wen Sun Xiuliang Cui Beifang Ning Xiao Li Zhuo Cheng Weiqi Jiang Cheng Zhang Xijun Liang Liang Li Xin Cheng Liu Hui Hongyang Wang Jin Ding | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 4 |
| 3 | Enlightenment from the COVID-19 Pandemic:The Roles of Environmental Factors in Future Public Health Emergency Response显示文摘The coronavirus disease 2019(COVID-19)pandemic is challenging the current public health emergency response systems(PHERSs)of many countries.Although environmental factors,such as those influencing the survival of viruses and their transmission between species including humans,play important roles in PHERSs,little attention has been given to these factors.This study describes and elucidates the roles of environmental factors in future PHERSs.To improve countries’capability to respond to public health emergencies associated with viral infections such as the COVID-19 pandemic,a number of environmental factors should be considered before,during,and after the responses to such emergencies.More specifically,to prevent pandemic outbreaks,we should strengthen environmental and wildlife protection,conduct detailed viral surveillance in animals and hotspots,and improve early-warning systems.During the pandemic,we must study the impacts of environmental factors on viral behaviors,develop control measures to minimize secondary environmental risks,and conduct timely assessments of viral risks and secondary environmental effects with a view to reducing the impacts of the pandemic on human health and on ecosystems.After the pandemic,we should further strengthen surveillance for viruses and the prevention of viral spread,maintain control measures for minimizing secondary environmental risks,develop our capability to scientifically predict pandemics and resurgences,and prepare for the next unexpected resurgence.Meanwhile,we should restore the normal life and production of the public based on the“One Health”concept,that views global human and environmental health as inextricably linked.Our recommendations are essential for improving nations’capability to respond to global public health emergencies. | Xiaolei Wang Fengchang Wu Xiaoli Zhao Xiao Zhang Junyu Wang Lin Niu Weigang Liang Kenneth Mei Yee Leung John P.Giesy | 2022 | Engineering2022，8，1： | 2 |
| 4 | Chemical characterization of Artemisia seed polysaccharide显示文摘 | ZHANG Ji WU Jian LIANG Junyu | 2007 | Carbohydrate Polymers2007，67，2： | 1 |
| 5 | Chemical characterization of Artemisia seed polysaccharide显示文摘 | ZHANG Ji WU Jian LIANG Junyu | 2007 | Carbohydrate Polymers2007，67，： | 1 |
| 6 | Consensus on potential biomarkers developed for use in clinical tests for schizophrenia显示文摘Background Schizophrenia is a serious mental illness affecting approximately 20 million individuals globally.Both genetic and environmental factors contribute to the illness.If left undiagnosed and untreated,schizophrenia results in impaired social function,repeated hospital admissions,reduced quality of life and decreased life expectancy.Clinical diagnosis largely relies on subjective evidence,including self-reported experiences,and reported behavioural abnormalities followed by psychiatric evaluation.In addition,psychoses may occur along with other conditions,and the symptoms are often episodic and transient,posing a significant challenge to the precision of diagnosis.Therefore,objective,specific tests using biomarkers are urgently needed for differential diagnosis of schizophrenia in clinical practice.Aims We aimed to provide evidence-based and consensus-based recommendations,with a summary of laboratory measurements that could potentially be used as biomarkers for schizophrenia,and to discuss directions for future research.Methods We searched publications within the last 10 years with the following keywords:‘schizophrenia’,‘gene’,‘inflammation’,‘neurotransmitter’,‘protein marker’,‘gut microbiota’,‘pharmacogenomics’and‘biomarker’.A draft of the consensus was discussed and agreed on by all authors at a round table session.Results We summarised the characteristics of candidate diagnostic markers for schizophrenia,including genetic,inflammatory,neurotransmitter,peripheral protein,pharmacogenomic and gut microbiota markers.We also proposed a novel laboratory process for diagnosing schizophrenia in clinical practice based on the evidence summarised in this paper.Conclusions Further efforts are needed to identify schizophrenia-specific genetic and epigenetic markers for precise diagnosis,differential diagnosis and ethnicity-specific markers for the Chinese population.The development of novel laboratory techniques is making it possible to use these biomarkers clinically to diagnose disease. | Ping Lin Junyu Sun Xiaoyan Lou Dan Li Yun Shi Zhenhua Li Peijun Ma Ping Li Shuzi Chen Weifeng Jin Shuai Liu Qing Chen Qiong Gao Lili Zhu Jie Xu Mengyuan Zhu Mengxia Wang Kangyi Liang Ling Zhao Huabin Xu Ke Dong Qingtian Li Xunjia Cheng Jinghong Chen Xiaokui Guo | 2022 | General Psychiatry2022，35，1： | 1 |
| 7 | Investigation of film cooling on the leading edge of turbine blade based on detached eddy simulation显示文摘In order to assess the influences of curved hole passage on cooling effectiveness and flow structure of turbine blade leading edge,the detached eddy simulation is applied to numerically investigate the AGTB turbine cascade under the condition of global blowing ratio M=0.7.The straight or curved cooling holes are located at either the pressure or suction side near the leading edge.The analysis and discussion focus on the local turbulence structure;influence of pressure gradient on the structure,and distribution of cooling effectiveness on the blade surface.The numerical results show that cooling hole with curved passage could bring positive impact on the increase of the local cooling effectiveness.On the suction side,the increased cooling effectiveness could be about 82% and about 77% on the pressure side,compared to the conventional straight hole. | LIANG JunYu KANG Shun | 2012 | Science China(Technological Sciences)2012，55，8： | 1 |
| 8 | Distal axis sulfide mineralization on the ultraslow-spreading Southwest Indian Ridge:an LA-ICP-MS study of pyrite from the East Longjing-2 hydrothermal field显示文摘The newly discovered East Longjing-2 hydrothermal field(ELHF-2)is located on the Dragon Horn oceanic core complex of the ultraslow-spreading Southwest Indian Ridge,approximately 12 km from the ridge axis.This study measured the chemical compositions of pyrite from ELHF-2 using a laser ablation inductively coupled plasma mass spectrometry(LA-ICP-MS)to investigate the genesis of the field.Three generations of pyrite were classified,and found that:Py1 and Py2,rich in V,Mn,U,and Se,occur in altered basalt debris and the silica alteration matrix,respectively.Py3 was mainly intergrown with chalcopyrite in quartz veins and had higher Cu,In,Ag,Sb,and Au contents than Py1 and Py2.Some elements,such as Au,Se,and Pb,are likely presented as direct substitution with Fe^(2+)in pyrite,while Cu,Zn,Co,Ni,and Ag probably occur both as direct substitution with Fe and as distributed micro-to nanoparticle-sized sulfides.Meanwhile,the occurrence of V,Mn,and U is likely presented as oxide inclusions.Trace element geochemistry suggested that the pyrite was formed under hightemperature conditions,and the ore forming elements were likely derived from ultramafic rocks.In addition,Py1and Py2 were formed under higher water/rock ratio and higher temperature conditions,with more seawater involvement compared with Py3.The formation of ELHF-2 was probably driven by exothermic serpentinization reactions with an additional magmatic heat.This study shows that high-temperature hydrothermal circulation driven by magmatic activity can be developed on distal rift flank areas of magma-starved ultraslow-spreading ridges. | Shili Liao Chuanwei Zhu Jianping Zhou Weiyong Liu Junyu Yu Jin Liang Weifang Yang Wei Li Jia Liu Chunhui Tao | 2021 | Acta Oceanologica Sinica2021，40，5： | 1 |
| 9 | Characterization,occurrence,environmental behaviors,and risks of nanoplastics in the aquatic environment:Current status and future perspectives显示文摘Microplastics(MPs)are emerging contaminants that have attracted worldwide attention in recent years.Compared with MPs,nanoplastics(NPs)may exhibit greater toxicity and higher potential risks because of their unique physiochemical nanoscale properties.However,the environmental fate,ecosystem toxicity,and potential risks associated with NPs have been less explored.This study summarizes the current research status of NPs through a comprehensive bibliometric analysis.The research hotspots and future trends of NPs were identified.We comprehensively searched the Web of Science Core Collection scientific database from its inception(2004)to November 26,2020.The results showed that the number of papers on NPs has increased significantly since 2014.The keywords used in NP research were divided into three clusters.Cluster 1 related to the physical,chemical,and biological behaviors of NPs in aquatic environments.Cluster 2 represented a relatively new and hot research field concerning the exposure,accumulation,and toxicity of NPs in organisms.Cluster 3 corresponded to the identification and quantification of NPs in marine environments and sediments.Moreover,we systematically elaborated the main areas of NP research,such as the characterization,occurrence,environmental behavior,ecological toxicity,and human health risks of NPs.The results showed that the quantification of NPs at environmentally relevant concentrations remains a challenge.Most studies have investigated polystyrene NPs,spherical NPs,and NPs in marine environments,while few studies have examined the aggregation,deposition,and ecological toxicity of NPs under environmentally relevant conditions.In addition,much less is known about the human health risks associated with NPs because little research has been conducted on estimating the overall human exposure to NPs and its effect.Finally,the current challenges and future perspectives of NP research are discussed. | Junyu Wang Xiaoli Zhao Fengchang Wu Lin Niu Zhi Tang Weigang Liang Tianhui Zhao Mengyuan Fang Hongzhan Wang Xiaolei Wang | 2021 | Fundamental Research2021，1，3： | 0 |
| 10 | Modulating the tumor microenvironment via oncolytic virus and PI3K inhibition synergistically restores immune checkpoint therapy response in PTEN-deficient glioblastoma显示文摘Dear Editor,Glioblastoma(GBM)is a lethal primary brain cancer,with a median survival of less than 2 years.1 Immune checkpoint blockades(ICBs)have revolutionized cancer therapy in the last decade,but they have little clinical benefit in GBM.1 Genomic and transcriptomic analysis revealed a significant enrichment of PTEN mutations in GBM patients resistant to ICBs.2 PTEN deficiency activates the phosphatidylinositol 3-kinase(PI3K)-AKT pathway to shape an immunosuppressive microenvironment. | Fan Xing Jingshu Xiao Junyu Wu Jiaming Liang Xiaoyu Lu Liping Guo Ping Li Panpan Hou Chunmei Li Deyin Guo | 2021 | Signal Transduction and Targeted Therapy2021，6，8： | 0 |
| 11 | Combined QTL mapping,GWAS and transcriptomic analysis revealed a candidate gene associated with the timing of spring bud flush in tea plant(Camellia sinensis)显示文摘Dear Editor,The timing of the spring bud f lush(TBF)is a crucial agro-nomic trait for the tea plant,as it strongly influences the yield and economic value of harvested fresh tea leaves.The TBF of tea plant is generally defined as the date when>30%of the growing tender shoots have reached the stage of one bud with one to three leaves,referred as to the stage of one and a bud,two and a bud,and three and a bud,respectively. | Yujie Liu Si Chen Chenkai Jiang Haoran Liu Junyu Wang Weizhong He Doogyung Moon Jiedan Chen Liang Chen Jianqiang Ma | 2023 | Horticulture Research2023，10，9： | 0 |
| 12 | State-of-the-art applications of machine learning in the life cycle of solid waste management显示文摘Due to the superiority of machine learning(ML)data processing,it is widely used in research of solid waste(SW).This study analyzed the research and developmental progress of the applications of ML in the life cycle of SW.Statistical analyses were undertaken on the literature published between 1985 and 2021 in the Science Citation Index Expanded and Social Sciences Citation Index to provide an overview of the progress.Based on the articles considered,a rapid upward trend from 1985 to 2021 was found and international cooperatives were found to have strengthened.The three topics of ML,namely,SW categories,ML algorithms,and specific applications,as applied to the life cycle of SW were discussed.ML has been applied during the entire SW process,thereby affecting its life cycle.ML was used to predict the generation and characteristics of SW,optimize its collection and transportation,and model the processing of its energy utilization.Finally,the current challenges of applying ML to SW and future perspectives were discussed.The goal is to achieve high economic and environmental benefits and carbon reduction during the life cycle of SW.ML plays an important role in the modernization and intellectualization of SW management.It is hoped that this work would be helpful to provide a constructive overview towards the state-of-the-art development of SW disposal. | Rui Liang Chao Chen Akash Kumar Junyu Tao Yan Kang Dong Han Xianjia Jiang Pei Tang Beibei Yan Guanyi Chen | 2023 | Frontiers of Environmental Science & Engineering2023，17，4： | 0 |
| 13 | YWHAH activates the HMGA1/PI3K/AKT/mTOR signaling pathway by positively regulating Fra-1 to affect the proliferation of gastric cancer cells显示文摘Fos-related antigen 1(Fra-1)is a nuclear transcription factor that regulates cell growth,differentiation,and apoptosis.It is involved in the proliferation,invasion,apoptosis and epithelial mesenchymal transformation of malignant tumor cells.Fra-1 is highly expressed in gastric cancer(GC),affects the cycle distribution and apoptosis of GC cells,and participates in GC occurrence and development.However,the detailed mechanism of Fra-1 in GC is unclear,such as the identification of Fra-1-interacting proteins and their role in GC pathogenesis.In this study,we identified tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta(YWHAH)as a Fra-1-interacting protein in GC cells using co-immunoprecipitation combined with liquid chromatography-tandem mass spectrometry.Experiments showed that YWHAH positively regulated Fra-1 mRNA and protein expression,and affected GC cell proliferation.Whole proteome analysis showed that Fra-1 affected the activity of the high mobility group AT-hook 1(HMGA1)/phosphatidylinositol-4,5-bisphosphate 3-kinase(PI3K)/protein kinase B(AKT)/mechanistic target of rapamycin(mTOR)signaling pathway in GC cells.Western blotting and flow cytometry confirmed that YWHAH activated HMGA1/PI3K/AKT/mTOR signaling pathway by positively regulating Fra-1 to affect GC cell proliferation.These results will help to discover new molecular targets for the early diagnosis,treatment,and prognosis prediction of GC. | JUNYU HE FENG ZENG XI JIN LIN LIANG MENGXIANG GAO WENTAO LI GUIYUAN LI YANHONG ZHOU | 2023 | Oncology Research2023，31，4： | 0 |
| 14 | Impact assessment of genetically modified herbicide-tolerant cotton on arthropod communities显示文摘Background:Cotton(Gossypium spp.)is one of the most important economic crops worldwide,and its production plays an important role in the economy of many countries.Genetically modified herbicide-tolerant(GMHT)crops,which were developed to minimize the losses caused by weeds,have gradually become the most widely adopted genetically modified crops in the world due to their economic and environmental benefits.However,the potential ecological and environmental risks of GMHT crops have attracted extensive attention and controversy.Arthropod communities form a promine nt part of the biodiversity of agroecosystems and are important indicators of environmental health.Elucidating the effects of GMHT crops on the diversity of arthropod communities is necessary to ensure the safety of GMHT crops.Result:In this 2-year study,we investigated the potential impact of GMHT crops on arthropod communities.The GMHT cotton variety GGK2 with glyphosate tolerance and its near-isogenic non-GMHT variety K312 were used for the experimental groups.The Shannon diversity index(H),Simpson diversity index(D),Pielou evenness index(J),and principal co-ordinates analysis(PCoA)of the Bray-Curtis distance were used to evaluate the population dynamics and biodiversity of arthropods in cotton fields.No significant differences were found between GGK2 and K312 in their total abundance of arthropod communities,and biodiversity indexes on most sampling dates.The arthropod composition in the GGK2 and K312 plots was similar.Sampling elates had a significant effect on biodiversity indexes,whereas no clear tendencies related to cotton variety or cotton variety x sampling elates interaction were recorded.In addition,PCoA revealed high similarity between the arthropod communities in the plots of the GMHT cotton variety GGK2 and its near-isogenic variety K312.Conclusion:There was no obvious difference in abundance,diversity indexes of arthropod communities between GMHT cotto n variety GGK2 and its near-isogenic variety K312 under the small-scale plan ting regime. | LI Dongyang ZHU Xiangzhen ZHANG Kaixin WANG Li ZHANG Rui LIANG Chengzhen LUO Junyu CUI Jinjie | 2022 | Journal of Cotton Research2022，5，2： | 0 |
| 15 | Oriented Generation of Novel Thermo-Sensitive Genic Male Sterile Lines with Improved Grain Shape and Outcrossing Rate in Early-Season Rice显示文摘Two-line hybrid rice with excellent quality is preferred in the Chinese market.However,there is a trade-off between reducing costs for hybrid seed production and lowering the outcrossing rate of the sterile line,which is largely determined by the stigma exsertion rate(SER).In this study,we constructed mutants of male sterility lines with improved grain length(GL)and SER in three elite early-season indica rice varieties through targeted manipulation of the TMS5 and GS3 genes using CRISPR/Cas9-mediated multiplex systems.We obtained a series of marker-free gs3 single mutants and gs3tms5 double mutants with significantly higher SER,longer grains,and increased 1000-grain weight compared with the wild type(WT).Importantly,the typically thermo-sensitive genic male sterile(TGMS)trait with a higher SER was observed in gs3tms5 mutants,and their F1 hybrids exhibited remarkable improvements in grain shape and yield-related traits.Our findings provided an efficient method to generate new valuable TGMS germplasm with improved SER through the mutagenesis of GS3 and TMS5 synergistically,and demonstrated that GS3 had pleiotropic effects on grain size,SER,and grain quality in early-season indica rice. | ZHANG Huali CHEN Junyu LI Ruiqing WANG Huimei DAI Dongqing LIANG Minmin WU Mingyue MA Liangyong | 2024 | Rice science2024，31，2： | 0 |
| 16 | m6A RNA methylation-mediated HNF3γ reduction rendershepatocellular carcinoma dedifferentiation and sorafenibresistance显示文摘Hepatocyte nuclear factor 3γ(HNF3γ)is a hepatocyte nuclear factor,but its role and clinical significance in hepatocellular carcinoma(HCC)remain unclear.Herein,we report that HNF3γexpression is downregulated in patient HCC and inversely correlated with HCC malignancy and patient survival.Moreover,our data suggested that the HNF3γreduction in HCC could be mediated by METTL14-dependent m6A methylation of HNF3γmRNA.HNF3γexpression was increased during hepatic differentiation and decreased in dedifferentiated HCC cells.Interestingly,HNF3γdelivery promoted differentiation of not only HCC cells but also liver CSCs,which led to suppression of HCC growth.Mechanistic analysis suggested an HNF3γ-centered regulatory network that includes essential liver differentiation-associated transcription factors and functional molecules,which could synergistically facilitate HCC cell differentiation.More importantly,enforced HNF3γexpression sensitized HCC cells to sorafenib-induced growth inhibition and cell apoptosis through transactivation of OATP1B1 and OATP1B3 expression,which are major membrane transporters for sorafenib uptake.Clinical investigation showed that patient-derived HCC xenografts with high HNF3γexpression exhibited a sorafenib response and patients with high HCC HNF3γlevels benefited from sorafenib therapy.Together,these results suggest that HNF3γplays an essential role in HCC differentiation and may serve as a therapeutic target and predictor of sorafenib benefit in patients. | Tengfei Zhou Shichao Li Daimin Xiang Junyu Liu Wen Sun Xiuliang Cui Beifang Ning Xiao Li Zhuo Cheng Weiqi Jiang Cheng Zhang Xijun Liang Liang Li Xin Cheng Liu Hui Hongyang Wang Jin Ding | 2021 | Signal Transduction and Targeted Therapy2021，6，1： | 0 |
| 17 | Tunable and efficient microwave absorption from mesophase pitch carbide with designable electromagnetic properties显示文摘In order to obtain the microwave absorption(MA)materials with light weight,high efficiency and tunable properties,the carbonized mesophase pitch(CMP)with the variation in carbonization temperatures and particle sizes were prepared and characterized.The carbonization temperature mainly controlled the graphitization degree of the CMP to affect their conductive loss.The carbon residues were generated on the CMP surface when the temperature was higher than 700℃,which contributed significantly to the polarization loss of the CMP.For scale regulation,the segregation between the particles in the paraffin ring caused by the reduction particles of CMP carbonization at 750℃(750 CMP)resulted in a significant reduction in conductive losses while improving their impedance matching.The 750 CMP over 300 mesh sieved had the strongest MA properties of-53 d B at 3.4 GHz within 5.5 mm.Moreover,the prepared CMPs were multi-layer compounded and optimized by CST microwave studio.The synergistic effect derived from the improved impedance matching and the enhanced interfacial polarization resulted in significant reflection loss in multi-layer CMP.Overall,these findings lead to the systematically regulation of carbon-based materials for MA,showing an attractive application prospect for the preparation of high-performance MA materials. | Junyu Lu Haoruo Zhang Yang Chen Mushan Yuan Mei Liang Zhengguang Heng Huawei Zou | 2023 | Defence Technology(防务技术)2023，28，10： | 0 |
| 18 | A backbone parent contributes core genomic architecture to pedigree breeding of early-season indica rice显示文摘Due to the capacity to deliver favorable target traits to offspring via breeder selection,backbone parents carrying accumulated favorable agronomic traits have been used widely in breeding programs in crop species,such as rice,wheat,cotton,and maize(Zhou et al.,2016;Fradgley et al.,2019;Li et al.,2019;Ma et al.,2019;Han et al.,2020).It is estimated that 3656(~70%)of the major Chinese rice varieties released from the year 1950e2008 were found to be derived from as few as 35 backbone parents(Tang et al.,2012).Large-scale genome sequencing of diverse rice accessions has been emerged as a promising technology for the identification of key genomic regions or loci under selection during rice domestication(Huang et al.,2012;Wang et al.,2018)and genetic improvement(Xie et al.,2015).On the other hand,sequence information derived from breeding pedigrees could also help to unravel how favorable genomic regions were transmitted from parents to their offspring,as demonstrated by the researches on the pedigrees of the wellknown rice varieties Minghui 63 and Huanghuazhan(Zhou et al.,2016;Chen et al.,2017;Huang et al.,2018).These researches enhanced the understanding of the cumulative effects of beneficial alleles at limited loci in selected offspring varieties.A few examples include IPA1,Gn1a,GW5,GS3,and GS5 for high grain yield,Waxy for good grain eating quality,and Xa21 for high adversity adaptability. | Junyu Chen Huali Zhang Shuhan Deng Huilong Du Zhuo Chen Yuhui Zhao Dongqing Dai Chengzhen Liang Ximing Li Chengzhi Liang Rui Zhang Liangyong Ma | 2021 | Journal of Genetics and Genomics2021，48，11： | 0 |
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