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| 1 | Land-walking vs.water-walking interventions in older adults:Effects on aerobic fitness显示文摘Background:Low cardiorespiratory fitness is an independent predictor of all-cause and cardiovascular mortality,and interventions that increase fitness reduce risk.Water-walking decreases musculoskeletal impact and risk of falls in older individuals,but it is unclear whether water-walking improves aerobic fitness in the same way as weight-dependent land-walking.This randomized controlled trial involved 3 intervention groups—a no-exercise control group(CG),a land-walking(LW)group,and a water-walking(WW)group—to investigate the comparative impacts of LWandWWto CG on fitness.Methods:Both exercise groups attended individually tailored,center-based,intensity-matched 3×weekly sessions for 24 weeks,which progressed to 150 min of exercise per week.This was followed by a 24-week no-intervention period.Maximal graded exercise tests were performed on a treadmill at Weeks 0,24,and 48.Results:Maximal oxygen uptake increased from Week 0 to Week 24 in both exercise groups(0.57±0.62 mL/kg/min,0.03±0.04 L/min for LW;0.93±0.75 mL/kg/min,0.06±0.06 L/min for WW,mean±SE)compared to the CG(-1.75±0.78 mL/kg/min,-0.16±0.05 L/min)(group×time,p<0.05).Time to exhaustion increased significantly following LW only(123.4±25.5 s),which was significantly greater(p=0.001)than the CG(24.3±18.5 s).By Week 48,the training-induced adaptations in the exercise groups returned to near baseline levels.Conclusion:Our study supports current physical-activity recommendations that 150 min/week of moderate-intensity exercise produces improvements in fitness in previously sedentary older individuals.Also,LW andWW elicit similar improvements in fitness if conducted at the same relative intensities.Exercise-na?ve older individuals can benefit from the lower impact forces and decreased risk of falls associated withWWwithout compromising improvements in cardiorespiratory fitness. | Andrew Haynes Louise H.Naylor Howard H.Carter Angela L.Spence Elisa Robey Kay L.Cox Barbara A.Maslen Nicola T.Lautenschlager Nicola D.Ridgers Daniel J.Green | 2020 | Journal of Sport and Health Science2020，9，3： | 2 |
| 2 | Spine Update: Lumbar Foraminal Stenosis显示文摘 | Louis G. Jenis Howard S. An | 2000 | Spine2000，，3： | 2 |
| 3 | Splenic artery and coronary vein occlusion for bleeding esophageal varices显示文摘 | Louis R. M. Guercio M.D. W. John B. Hodgson M.B. M.S. Jean C. Morgan M.B. B.S. Howard L. Berman M.D. Mahesh N. Kinkhabwalla M.D | 1984 | World Journal of Surgery1984，，5： | 1 |
| 4 | Clinical Pharmacokinetics of Pregabalin in Healthy Volunteers显示文摘 | Howard N. Bockbrader Louis L. Radulovic Edward L. Posvar James C. Strand Christine W. Alvey Janice A. Busch Edward J. Randinitis Brian W. Corrigan George M. Haig Rebecca A. Boyd David L. Wesche | 2010 | Journal of Clinical Pharmacology2010，，8： | 1 |
| 5 | Professional identity creation: Examining the development of beginning preservice teachers’ understanding of their work as teachers显示文摘 | Louise Sutherland Sarah Howard Lina Markauskaite | 2009 | Teaching and Teacher Education2009，，3： | 1 |
| 6 | Variability in measurement of abdominal aortic aneurysms显示文摘 | Frank A. Lederle Samuel E. Wilson Gary R. Johnson Donovan B. Reinke Fred N. Littooy Charles W. Acher Louis M. Messina David J. Ballard Howard J. Ansel for the Abdominal Aortic Aneurysm Detection Management Veterans Administration Cooperative Study Group* | 1995 | Journal of Vascular Surgery1995，，： | 1 |
| 7 | Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control: 10-Year Results From the Oxford Vascular Study显示文摘 | Dominic P.J. Howard Amitava Banerjee Jack F. Fairhead Jeremy Perkins Louise E. Silver Peter M. Rothwell | 2013 | Circulation2013，，20： | 1 |
| 8 | Pathophysiology and manifestation of myeloma显示文摘 | Dan L L Howard H G Louise B G | 2001 | MKSAP (oncology)2001，5355，： | 1 |
| 9 | Professional identity creation:Examining the development of beginning preservice teachers' understanding of their work as teachers显示文摘 | LOUISE SUTHERLAND SARAH HOWARD LINA MARKAUSKAITE | | 0，，26： | 1 |
| 10 | Professional identity creation: Examining the development of beginning preservice teachers’ understanding of their work as teachers显示文摘 | Louise Sutherland Sarah Howard Lina Markauskaite | 2009 | Teaching and Teacher Education2009，，3： | 1 |
| 11 | Risk of hip fracture in patients with a history of schizophrenia显示文摘 | LOUISE HOWARD GRAHAM KIRKWOOD MORVEN LEESE | 2007 | BJP2007，190，： | 1 |
| 12 | Compositional and toxicological analysis of a GM potato line with reduced α-solanine content – A 90-day feeding study in the Syrian Golden hamster显示文摘 | S?ren Langkilde Malene Schr?der Thomas Frank Louise V.T. Shepherd Sean Conner Howard V. Davies Otto Meyer Jürgen Danier Michael Rychlik William R. Belknap Kent F. McCue Karl-Heinz Engel Derek Stewart Ib Knudsen Morten Poulsen | 2012 | Regulatory Toxicology and Pharmacology2012，，1： | 1 |
| 13 | The Expression of the Urokinase Plasminogen Activator System in Metastatic Murine Osteosarcoma:An in Vivo Mouse Model显示文摘 | Jane Lisette Fisher Peter Scott Mackie Monique Louise Howard | 2001 | Clinical Cancer Research2001，7，： | 1 |
| 14 | Therapy-related acute promyelocytic leukemia after chemoradiotherapy with capecitabine for rectal adenocarcinoma显示文摘 | Armin Rashidi Louise Man John R. Howard Daniel Atienza Stephen I. Fisher | 2014 | Leukemia & Lymphoma2014，，3： | 1 |
| 15 | Attitudes and adjustment to the parental role in mothers following treatment for postnatal depression显示文摘 | Ming Wai Wan Deborah J. Sharp Louise M. Howard Kathryn M. Abel | 2011 | Journal of Affective Disorders2011，，： | 1 |
| 16 | Effect of visceral metastases on the efficacy and safety of everolimus in postmenopausal women with advanced breast cancer: Subgroup analysis from the BOLERO-2 study显示文摘 | Mario Campone Thomas Bachelot Michael Gnant Ines Deleu Hope S. Rugo Barbara Pistilli Shinzaburo Noguchi Mikhail Shtivelband Kathleen I. Pritchard Louise Provencher Howard A. Burris Lowell Hart Bohuslav Melichar Gabriel N. Hortobagyi Francis Arena José Bas | 2013 | European Journal of Cancer2013，，12： | 1 |
| 17 | PI3K Regulation of RAC1 Is Required for Kras-Induced Pancreatic Tumorigenesis in Mice显示文摘 | Chia-Yen C. Wu Eileen S. Carpenter Kenneth K. Takeuchi Christopher J. Halbrook Louise V. Peverley Harold Bien Jason C. Hall Kathleen E. DelGiorno Debjani Pal Yan Song Chanjuan Shi Richard Z. Lin Howard C. Crawford | 2014 | Gastroenterology2014，，： | 1 |
| 18 | Regulation and postsynaptic binding of neurexins - drug targets for neurodevelopmental and neuropsychiatric disorders显示文摘Neurexins (NRXN ) 被连接了到 neurodevelopmental 和 neuropsychiatric 混乱并且成为了吸引人的药目标。他们是 transmembrane neuronal 粘附分子并且在触处和 synaptic 活动的形成和区别起重要作用。NRXN 的许多 postsynaptic 绑定搭挡被识别了。在 NRXN 和 postsynaptic 绑定搭挡之间的相互作用能被其他的拼接, synaptic 活动,和 RNA 绑定调整蛋白质。postsynaptic 交互搭挡可以为 NRXN 与对方竞争有约束力。NRXN 的表示能也 transcriptionally 并且 post-transcriptionally 被调整。基因多型性可以影响 NRXN 的函数和表达式。在这评论,我们将在这些区域总结最近的进展。理解 neurexin 发信号的生物学为开发基于 neurexin 的药是必要的。 | Yicheng DingL Linda Howard Louise Gallagher Sanbing Shen | 2015 | Frontiers in Biology2015，10，3： | 0 |
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