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| 1 | Effects of Percutaneous Coronary Intervention on Serum Angiopoietin-2 in Patients with Coronary Heart Disease显示文摘 | Zhi-Yu Zeng Chun Gui Lang Li Xiao-Min Wei | 2016 | Chinese Medical Journal2016，，6： | 22 |
| 2 | Molecular basis of pathogenesis of emerging viruses infecting aquatic animals显示文摘Aquatic vertebrates are very abundant in the world,and they are of tremendous importance in providing global food security and nutrition.However,emergent and resurgent viruses,such as ranavirus(e.g.,Rana grylio virus,RGV and Andriasd avidianus ranavirus,ADRV),herpesvirus(e.g.,Carassius carassius herpesvirus,CaHV),reovirus(e.g.,grass carp reovirus 109,GCRV-109,Scophthal musmaximus reovirus,SMReV and Micropterus salmoides reovirus,MsReV),and rhabdovirus(e.g.,Siniper cachuatsi rhabdovirus,SCRV and Scophthal musmaximus rhabdovirus,SMRV)can cause severe diseases in aquaculture animals and wild lower vertebrates,such as frogs,giant salamanders,fish,and so on.Here,we will briefly describe the symptoms produced by the aforementioned viruses and the molecular basis of the virus ehost interactions.This manuscript aims to provide an overview of viral diseases in lower vertebrates with an emphasis on visible symptomatic manifestations and pathogenesis. | Lang Gui V.Gregory Chinchar Qiya Zhang | 2018 | Aquaculture and Fisheries2018，3，1： | 12 |
| 3 | An-Luo-Hua-Xian Pill Improves the Regression of Liver Fibrosis in Chronic Hepatitis B Patients Treated with Entecavir显示文摘Background and Aims:Chronic hepatitis B(CHB)can cause liver fibrosis and lead to cirrhosis and cancer.As the effectiveness of antiviral therapy to reverse liver fibrosis is limited,We aimed to evaluate the effect of An-Luo-Hua-Xian pill(ALHX)on fibrosis regression in CHB patients treated with entecavir(ETV).Methods:Treatment-naïve patients with CHB were randomly treated with ETV alone or combined with ALHX(ETV+ALHX)between October 1,2013 and December 31,2020.Demographic,laboratory,and liver histology data before and after 78 weeks of treatment were collected.The Ishak fibrosis score(F)was used and fibrosis regression required a decrease in F of≥1 after treatment.Results:A total of 780 patients were enrolled,and 394 with a second liver biopsy after treatment were included in the per-protocol population,132 in ETV group and 262 in ETV+ALHX group.After 78 weeks of treatment,the fibrosis regression rate in the ETV+ALHX group was significantly higher than that of the ETV group at baseline F≥3 patients:124/211(58.8%)vs.45/98(45.9%),p=0.035.The percentage of patients with a decreased liver stiffness measurement(LSM)was higher in the ETV+ALHX group:156/211(73.9%)vs.62/98(63.%),p=0.056.Logistic regression analysis showed that ETV combined with ALHX was associated with fibrosis regression[odds ratio(OR)=1.94,p=0.018],and a family history of hepatocellular carcinoma was on the contrary.(OR=0.41,p=0.031).Conclusions:ETV combined with ALHX increased liver fibrosis regression in CHB patients. | Yi-Qi Liu Chi Zhang Jia-Wen Li Li-Hua Cao Zhan-Qing Zhang Wei-Feng Zhao Qing-Hua Shang Da-Zhi Zhang An-Lin Ma Qing Xie Hong-Lian Gui Guo Zhang Ying-Xia Liu Jia Shang Shi-Bin Xie Jun Li Xu-Qing Zhang Zhi-Qiang Zou Yu-Ping Chen Zong Zhang Ming-Xiang Zhang Jun Cheng Fu-Chun Zhang Li-Hua Huang Jia-Bin Li Qing-Hua Meng Hai-Bin Yu Yu-Qiang Mi Yan-Zhong Peng Zhi-Jin Wang Li-Ming Chen Fan-Ping Meng Wan-Hua Ren Lang Bai Yi-Lan Zeng Rong Fan Xian-Zhi Lou Wei-Feng Liang Hui Liu Hui Zhuang Hong Zhao Gui-Qiang Wang | 2023 | Journal of Clinical and Translational Hepatology2023，11，2： | 7 |
| 4 | Synthesis of Large-Area, Few-Layer Graphene on Iron Foil by Chemical Vapor Deposition显示文摘我们表明一个简单、可控制的方法综合大区域,由优化化学蒸汽免职(CVD ) 的铁底层上的很少层 graphene 用甲烷和氢的混合物的方法。基于 Fe-C 阶段图的分析,为 Fe 表面上的 graphene 的成功的合成的一个合适的过程被设计。适当温度和冷却过程被发现在高度水晶的很少层 graphene 的合成很重要。基于 Graphene 的地效果晶体管(联邦货物税) 设备用产生很少层 graphene 被制作,并且与 3001150 cm2/ 的提取活动性显示出好质量(V 敢椠 ?? 敤瑢吗? | Yunzhou Xue Bin Wu Yunlong Guo Liping Huang Lang Jiang Jianyi Chen Dechao Geng Yunqi Liu Wenping Hu Gui Yu | 2011 | Nano Research2011，4，12： | 7 |
| 5 | Clinical observation on pericardial effusion in patients with lung cancer treated by intrapericardial catheterization and infusion of highly agglutinative staphylococcin and cisplatin显示文摘Objective: To evaluate the therapeutic efficacy of injecting highly agglutinative staphylococcin (HASL) and cisplatin into pericardial cavity of lung cancer patients with pericardial effusion. Methods: 81 patients were randomized into two groups: 45 in the experimental group (HASL and Cisplatin) and 36 in the control group (Cisplatin). At first pericardial effusion was drained out from a intrapericardial catheter and then different drugs were infused, respectively. 24 h after perfusion the draining continued again until drainage quantity was less than 30 mL every day. The draining lasted 10–15 days. Results: The response rate was 91.1% for the experimental group and 80.6% for the control group. There was no significant difference between the two groups (P>0.05). The complete remission was 77.8% for the experimental group and 52.8% for the control group, which was statistically significant difference (P<0.05). The adverse effects were myelosuppression and nausea and vomiting, which were 35.6% and 40.0% in the experimental group and 72.2% and 66.7% in the control group, respectively (P<0.01, P<0.05). Conclusion: Inject- ing HASL and cisplatin into pericardial cavity may be a better way to control pericardial effusion of lung cancer. | Qi'an Jiang Yide Zhou Gui'e Cheng Fangyun Gong Shuyan Zhang Fengping Lang Meihong Zhao | 2006 | The Chinese-German Journal of Clinical Oncology2006，5，5： | 3 |
| 6 | Recent insights into aquatic viruses: Emerging and reemerging pathogens, molecular features, biological effects, and novel investigative approaches显示文摘Aquatic viruses are naturally present in the aquatic environment and the number of viruses is staggering.Various multicellular organisms in aquatic ecosystems may be infected,cross-species transmitted,manipulated,and killed by aquatic viruses,which can lead to cascading ecological effects.The viruses in unicellular aquatic organisms can alter interactions between host individuals,and are essential in effecting or maintaining the dynamics of aquatic microbial communities,horizontal gene transfer,biodiversity,and modulating ecological processes globally.Meanwhile,hosts also impact viral abundance and diversity.Microbial diversity drives multifunctionality in ecosystems,while viruses shape complex microbial communities and are crucial for ecosystem functioning.This review focuses on molecular,genetic,evolutionary,and ecosystemic advances related to emerging and reemerging aquatic viruses,presents the contexts,novel tools,and investigative approaches pertaining to the study of aquatic virology,and discusses the mechanisms by which viruses affect aquatic ecosystems.The paper provides an efficient and broadly-based blueprint for improving understanding of aquatic viruses. | Qi-Ya Zhang Fei Ke Lang Gui Zhe Zhao | 2022 | Water Biology and Security2022，1，4： | 1 |
| 7 | Microstructure and property of SiC coating for carbon materials 显示文摘 | ZHAO Juan WANG Gui GUO Quan-gui LIU Lang | 2007 | Fusion Engineering and Design2007，82，： | 1 |
| 8 | Effect of Ti dopant on shrinkage and performance of MCMB-derived carbon laminations显示文摘 | Zhan Jun Liu Quan Gui Guo Jin Ren Song Lang Liu | 2006 | Carbon2006，，1： | 1 |
| 9 | Microstructure and property of SiC coating for carbon materials显示文摘 | LIU Lang ZHAO Juan WANG Gui | 2007 | Fusion Engineering and Design2007，82，4： | 1 |
| 10 | Blocking the large extracellular loop (LEL) domain of Fc Tetraspanin-3 could inhibit the infection of white spot syndrome virus (WSSV) in Chinese shrimp, Fenneropenaeus chinensis显示文摘 | Lang Gui Bing Wang Fu-Hua Li Yu-Miao Sun Zhan Luo Jian-Hai Xiang | 2012 | Fish and Shellfish Immunology2012，，6： | 1 |
| 11 | Molecular identification and expression analysis of foxl2 and sox9b in Oryzias celebensis显示文摘Oryzias celebensis is determined by an XX-XY system,however,its sex-related genes have not been confirmed.The genes foxl2 and sox9b are important for gonadal development in vertebrates.In the present study,the foxl2 and sox9b cDNAs were cloned and their expression patterns were analyzed.The cDNA sequence of foxl2 and sox9b were obtained by rapid amplification of cDNA ends(RACEs).Reverse transcription polymerase chain reaction(RT-PCR)showed that O.celebensis foxl2(Ocfoxl2)transcript was predominately expressed in the ovary while O.celebensis sox9b(Ocsox9b)transcript was mainly expressed in the testis.In embryos,Ocfoxl2 transcript was first detected in gastrula.In contrast,Ocsox9b transcript was of maternal origin as expression was detected at the two cell stage.By chromogenic and fluorescent in situ hybridization(ISH),Ocfoxl2 mRNA in the ovary was highly expressed in early oocytes and weakly expressed in the granulosa cells and thecal cells in the later oocytes.In contrast,Ocsox9b mRNA was mainly found in Sertoli cells surrounding spermatogonia and in spermatids and sperm in the testis.In summary,Ocfoxl2 identified somatic cells and differentiating oocytes in the ovary,indicating it is involved in ovarian development.Ocsox9b is identified in Sertoli cells and late developing male germ cells indicating it is involved in testicular development. | Yuli Zhao Yu Zhang Ying Zhong Jing Guo Mengyue Lu Lang Gui Mingyou Li | 2021 | Aquaculture and Fisheries2021，6，5： | 1 |
| 12 | Carbon/graphite seal materials prepared from mesoearbon mierobeads显示文摘 | SONG Yong zhong ZHAI Geng-tai LI Gui-sheng SHI Jing- li GUO Quan gui LIU Lang | 2004 | Carbon2004，42，： | 1 |
| 13 | A system identification based approach for pulsed eddy current non destructive evaluation 显示文摘 | LANG Z Q AGURTO A TIAN Gui yun | 2007 | Measurement Science and Technology2007，18，7： | 1 |
| 14 | Characterization and expression analysis of gonad specific igf3 in the medaka ovary显示文摘The gonad specific expression of insulin-like growth factor 3(igf3)has suggested an important role of igf3 in fish reproduction.In this study,medaka igf3 was isolated and its expression patterns were compared with igf1,and germ cell gene vasa in adult medaka ovary.Molecular cloning and sequencing showed that the open reading frame(ORF)of medaka igf3 was comprised of 501 nucleotides and encoded 166 amino acid residues.Reverse transcription polymerase chain reaction(RT-PCR)analysis showed that igf3 RNA was specifically expressed in developing embryos and adult gonads of both sexes.Real time quantitative PCR(q-PCR)indicated that igf3 expression was gradually increased during oogenesis,and reached its highest level at stage V.Using Chromogenic and fluorescent in situ hybridization,igf3 was shown to be present in the germ cells of oogonia and in oocytes at stages I-III,as well as abundant in granulosa cells and theca cells of oocytes at stages IV-V.In addition,igf3 and igf1 were expressed mutually in the outer theca cells of stage V oocytes in ovary.Collectively,we demonstrated that gonad specific igf3 could mark medaka ovarian somatic cells and germ cells.These findings highlight the importance of igf3 during ovarian development. | Jiale Xie Ying Zhong Yuli Zhao Wenjie Xie Jing Guo Lang Gui Mingyou Li | 2022 | Aquaculture and Fisheries2022，7，3： | 0 |
| 15 | Liver DNA methylation and transcriptome between 1- and 3-year-old grass carp显示文摘Diseases of grass carps often occur in juveniles but not in adults that may have established disease resistance during development.We performed both DNA bisulfite and transcriptome sequencing on liver libraries of 1-and 3-year-old grass carps.Differential DNA-methylation analysis exhibited a declined methylation level through development.Functional annotation revealed that identified differentially methylated genes(DMGs)and differentially expressed genes were enriched in immune-related pathways such as PI3K-Akt signaling pathway and its related pathways.Both differentially methylated and differentially expressed genes were clustered into the growth-and immune-related function networks.Subcellular localization analysis indicated that the DMGs localized on cell membrane were significantly enriched in calcium signaling pathway and neuroactive ligand-receptor interaction pathway,implying the importance of G protein-coupled receptors to development.These findings will broaden our understanding of the key genes and pathways that affect the immune system at different development stages and the developing protective strategies in grass carp. | Lang Gui Wenjie Lu Mijuan Shi Ruiqin Hu Yan zhou Yubang Shen Xiaoyan Xu Jie Liu Huimin Xia Yaping Wang Wenhao Li Ying Lu | 2022 | Aquaculture and Fisheries2022，7，3： | 0 |
| 16 | Medaka gcnf is a component of chromatoid body during spermiogenesis显示文摘Germ cells of many organisms exhibit a unique perinuclear cytoplasmic cloud-like structure called the chromatoid body(CB).Specific components of the CB,such as vasa,are crucial for germline development.Herein we identify another component of the CB,the Oryzias latipes gcnf homolog(Olgcnf).By reverse transcription polymerase chain reaction(RT-PCR),Olgcnf transcript was restricted to gonads in the adult tissues and was maternally provided and persisted throughout embryogenesis.By in situ hybridization on gonadal sections,Olgcnf transcript was restricted to germ cells.In the ovary,Olgcnf was predominantly expressed in the early stages of oocytes.In the testis,Olgcnf showed dynamic expression in round spermatids and sperm,accumulated in the CB during spermatid morphogenesis and concentrated in elongated spermatids of acrosome cap region and flagellar manchette.Moreover,Olgcnf was colocalized with vasa,which is the best-characterized component of the CB.Therefore,Olgcnf is specific to germ cells of both sexes and is a component of the CB during spermiogenesis. | Zinan Xie Peng Song Ying Zhong Jing Guo Lang Gui Mingyou Li | 2021 | Aquaculture and Fisheries2021，6，6： | 0 |
| 17 | Atmospheric environment monitoring technology and equipment in China:A review and outlook显示文摘Accurate monitoring of the atmospheric environment and its evolution are important for understanding the sources,chemical mechanisms,and transport processes of air pollution and carbon emissions in China,and for regulatory and control purposes.This study gives an overview of atmospheric environment monitoring technology and equipment in China and summarizes the major achievements obtained in recent years.China has made great progress in the development of atmospheric environment monitoring technology and equipment with decades of effort.The manufacturing level of atmospheric environment monitoring equipment and the quality of products have steadily improved,and a technical&production system that can meet the requirements of routine monitoring activities has been initiated.It is expected that domestic atmospheric environment monitoring technology and equipment will be able to meet future demands for routine monitoring activities in China and provide scientific assistance for addressing air pollution problems. | Youwen Sun Ting Yang Huaqiao Gui Xin Li Weigang Wang Jun Duan Shushuai Mao Hao Yin Bin Zhou Jianlei Lang Haijin Zhou Cheng Liu Pinhua Xie | 2023 | Journal of Environmental Sciences2023，，1： | 0 |
| 18 | Characterization and expression analysis of sox3 in medaka gonads显示文摘Numerous studies have showed that sox3 is involved in neurogenesis and sex differentiation in vertebrates.However,the accurate expression pattern is still unclear in fish.In this study,medaka sox3 was isolated and its expression patterns were compared with germ cell gene vasa in adult gonads.By reverse transcription-polymerase chain reaction(RT-PCR)analysis,sox3 RNA expression was detected in the brain,eyes and gonads.By chromogenic and fluorescent in situ hybridization,sox3 was present in the oogonia and early stages of oocytes as well as granulosa cells and theca cells in the later stages;in the testis,sox3 was occurred in the Sertoli cells and sperm with a specific signal in the location of chromatid body of sperm;in the embryos,sox3 was expressed in the central nervous.These results suggest that medaka sox3 gene was occurred in somatic and germ cells in adult gonads of both sexes,involved in the process of spermatogenesis,as well as the development of the nervous system.This study provides a precise expression pattern of sox3 and suggests that sox3 may be involved in gonadal and nervous system development of fish. | Quan Pu Yuan Ma Ying Zhong Jing Guo Lang Gui Mingyou Li | 2022 | Aquaculture and Fisheries2022，7，1： | 0 |
| 19 | Theoretical analysis and comparison of OAM waves generated by three kinds of antenna array显示文摘Antenna array is one of the methods which can generate Orbital Angular Momentum(OAM)waves.However,OAM waves generated by different antenna arrays have different characteristics of Electric-field(E-field)com-ponents'distribution and radiation patterns.In order to solve this problem,we derive E-feld formulas of OAM waves generated by different kinds of dipole antenna array in this paper.The dipole antenna arrays are arranged by three methods:1)antenna elements are in the same direction of y axis,2)antenna elements are in the radial direction and 3)antenna elements are in the azimuthal direction.Results show that x components,y components and z components carry different OAM modes under the three conditions.Simulation results show that the same direction antenna array produces the best OAM waves because the y component is dominated by OAM mode l and RHCP/LHCP waves are negligible in energy,while the pure OAM waves carried by the z components generated by the other two antenna arrays have little energy.In addition,only the radiation pattern ofl=0 produced by the same direction antenna array does not have a null zone in the propagation direction.Radiation patterns of l=±1 do not have null zones in the propagation direction generated by other two antenna arrays. | Dandan Liu Liangqi Gui Ke Chen Liang Lang Zixiao Zhang Han Chen Lixing Liu Tao Jiang | 2021 | Digital Communications and Networks2021，7，1： | 0 |
| 20 | Tool Condition Monitoring Based on Nonlinear Output Frequency Response Functions and Multivariate Control Chart显示文摘Tool condition monitoring(TCM)is a key technology for intelligent manufacturing.The objective is to monitor the tool operation status and detect tool breakage so that the tool can be changed in time to avoid significant damage to workpieces and reduce manufacturing costs.Recently,an innovative TCM approach based on sensor data modelling and model frequency analysis has been proposed.Different from traditional signal feature-based monitoring,the data from sensors are utilized to build a dynamic process model.Then,the nonlinear output frequency response functions,a concept which extends the linear system frequency response function to the nonlinear case,over the frequency range of the tooth passing frequency of the machining process are extracted to reveal tool health conditions.In order to extend the novel sensor data modelling and model frequency analysis to unsupervised condition monitoring of cutting tools,in the present study,a multivariate control chart is proposed for TCM based on the frequency domain properties of machining processes derived from the innovative sensor data modelling and model frequency analysis.The feature dimension is reduced by principal component analysis first.Then the moving average strategy is exploited to generate monitoring variables and overcome the effects of noises.The milling experiments of titanium alloys are conducted to verify the effectiveness of the proposed approach in detecting excessive flank wear of solid carbide end mills.The results demonstrate the advantages of the new approach over conventional TCM techniques and its potential in industrial applications. | Yufei Gui Ziqiang Lang Zepeng Liu Hatim Laalej | 2023 | Journal of Dynamics, Monitoring and Diagnostics2023，2，4： | 0 |
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