|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Episodic crustal anatexis and the formation of Paiku composite leucogranitic pluton in the Malashan Gneiss Dome, Southern Tibet显示文摘The Paiku composite leucogranitic pluton in the Malashan gneiss dome within the Tethyan Himalaya consists of tourmaline leucogranite,two-mica granite and garnet-bearing leucogranite.Zircon U-Pb dating yields that(1)tourmaline leucogranite formed at28.2±0.5 Ma and its source rock experienced simultaneous metamorphism and anatexis at 33.6±0.6 Ma;(2)two-mica granite formed at 19.8±0.5 Ma;(3)both types of leucogranite contain inherited zircon grains with an age peak at^480 Ma.These leucogranites show distinct geochemistry in major and trace elements as well as in Sr-Nd-Hf isotope compositions.As compared to the two-mica granites,the tourmaline ones have higher initial Sr and zircon Hf isotope compositions,indicating that they were derived from different source rocks combined with different melting reactions.Combined with available literature data,it is suggested that anatexis at^35 Ma along the Himalayan orogenic belt might have triggered the initial movement of the Southern Tibetan Detachment System(STDS),and led to the tectonic transition from compressive shortening to extension.Such a tectonic transition could be a dominant factor that initiates large scale decompressional melting of fertile high-grade metapelites along the Himalayan orogenic belt.Crustal anatexis at^28 Ma and^20 Ma represent large-scale melting reactions associated with the movement of the STDS. | GAO LiE ZENG LingSen HOU KeJun GUO ChunLi TANG SuoHan XIE KeJia HU GuYue WANG Li | 2013 | Chinese Science Bulletin2013，58，28： | 23 |
| 2 | Additive manufacturing of high-strength CrMnFeCoNi high-entropy alloys-based composites with WC addition显示文摘Laser melting deposition with WC addition has been developed to fabricate high-strength CrMnFeCoNibased high-entropy alloys-based composites.By this technique,a microstructure of compact refined equiaxed grains can be achieved,and the tensile strength can be remarkably improved.The sample with 5 wt%WC addition shows a promising mechanical performance with a tensile strength of 800 MPa and an elongation of 37%.The improvement in mechanical property may be attributed to the formation of Cr(23)C6 reinforcement precipitates,which could promote the heterogeneous nucleation of grains and hinder the propagation of slip bands. | Jinfeng Li Shuo Xiang Hengwei Luan Abdukadir Amar Xue Liu Siyuan Lu Yangyang Zeng Guomin Le Xiaoying Wang Fengsheng Qu Chunli Jiang Guannan Yang | 2019 | Journal of Materials Science & Technology2019，35，11： | 13 |
| 3 | Local and long-range transport influences on PM_(2.5) at a cities-cluster in northern China,during summer 2008显示文摘Hourly PM2.5 concentrations were observed simultaneously at a cities-cluster comprising 10 cities/towns in Hebei province in China from July 1 to 31,2008. Among the 10 cities/towns, Baoding showed the highest average concentration level(161.57(jig/m3) and Yanjiao exhibited the lowest(99.35(jig/m3). These observed data were also studied using the joint potential source contribution function with 24-h and72-h backward trajectories, to identify more clearly the local and countrywide-scale long-range transport sources. For the local sources, three important influential areas were found, whereas five important influential areas were defined for long-range transport sources. Spatial characteristics of PM2.5 were determined by multivariate statistical analyses. Soil dust, coal combustion, and vehicle emissions might be the potential contributors in these areas. The results of a hierarchical cluster analysis for back trajectory endpoints and PM2.5 concentrations datasets show that the spatial characteristics of PM2.5 in the cities-cluster were influenced not only by local sources, but also by long-range transport sources. Different cities in the cities-cluster obtained different weighted contributions from local or long-range transport sources. Cangzhou, Shijiazhuang, and Baoding are near the source areas in the south of Hebei province,whereas Zhuozhou, Yangfang, Yanjiao, Xianghe, and Langfang are close to the sources areas near Beijing and Tianjin. | Lijie Gao Yingze Tian Caiyan Zhang Guoliang Shi Huize Hao Fang Zeng Chunli Shi Meigen Zhang Yinchang Feng Xiang Li | 2014 | Particuology2014，12，2： | 9 |
| 4 | Evaluation system for CO_2 emission of hot asphalt mixture显示文摘The highway construction industry plays an important role in economic and development,but is also a primary source of carbon emission. Accordingly, with the global climate change, energy conservation and reduction of carbon emissions have become critical issues in the highway construction industry. However, to date, a model for the highway construction industry has not been established. Hence, to implement a low-carbon construction model for highways, this study divided asphalt pavement construction into aggregate stacking, aggregate supply, and other stages, and compiled a list of energy consumption investigation. An appropriate calculation model of CO_2 emission was then built. Based on the carbon emission calculation model, the proportion of carbon emissions in each stage was analyzed. The analytic hierarchy process was used to establish the system of asphalt pavement construction with a judgment matrix, thereby enabling calculation of the weight coefficient of each link. In addition, the stages of aggregate heating, asphalt heating, and asphalt mixture mixing were defined as key stages of asphalt pavement construction. Carbon emissions at these stages accounted for approximately 90% of the total carbon emissions. Carbon emissions at each stage and their impact on the environment were quantified and compared. The energy saving construction schemes as well as the environmental and socioeconomic benefits were then proposed. Through these schemes, significant reductions in carbon emissions and costs can be achieved. The results indicate that carbon emissions reduce by 32.30% and 35.93%, whereas costs reduce by 18.58% and 6.03%. The proposed energy-saving and emission reduction scheme can provide a theoretical basis and technical support for the development of low-carbon highway construction. | Bo Peng Chunli Cai Guangkai Yin Wenying Li Yaowen Zhan | 2015 | Journal of Traffic and Transportation Engineering(English Edition)2015，2，2： | 8 |
| 5 | Process intensification and energy saving of reactive distillation for production of ester compounds显示文摘Reactive distillation(RD) process is an innovative hybrid process combining reaction with distillation, which has recently come into sharp focus as a successful case of process intensification. Considered as the most representative case of process intensification, it has been applied for many productions, especially for production of ester compounds. However, such problems existing in the RD system for ester productions are still hard to solve,as the removal of the water which comes from the esterification, and the separation of the azeotropes of ester–alcohol(–water). Many methods have been studying on the process to solve the problems resulting in further intensification and energy saving. In this paper, azeotropic–reactive distillation or entrainer enhanced reactive distillation(ERD) process, reactive extractive distillation(RED) process, the method of co-production in RD process, pressure-swing reactive distillation(PSRD) process, reactive distillation–pervaporation coupled process(RD–PV), are introduced to solve the problems above, so the product(s) can be separated efficiently and the chemical equilibrium can be shifted. Dividing-wall column(DWC) structure and novel methods of loading catalyst are also introduced as the measures to intensify the process and save energy. | Chunli Li Cong Duan Jing Fang Hongshi Li | 2019 | Chinese Journal of Chemical Engineering2019，27，6： | 6 |
| 6 | A review:Modification strategies of nickel-rich layer structure cathode(Ni≥0.8)materials for lithium ion power batteries显示文摘Lithium ion power batteries have undoubtedly become one of the most promising rechargeable batteries at present;nonetheless,they still suffer from the challenges such as requirement of even higher energy density and capacity retention.Nickel-rich layer oxides(Ni≥0.8)become ideal cathode materials to achieve the high specific capacity.Integration of optimization of synthesis process and modification of crystal structure to suppress the capacity fading can obviously improve the performance of the lithium ion batteries.This review presents the recent modification strategies of the nickel-rich layered oxide materials.Unlike in previous reviews and related papers,the specific mechanism about each type of the modification strategies is specially discussed in detail,which is mainly about inhibiting the anisotropic lattice strain and adjusting the cation mixing degree to maintain crystal structure.Based on the recent progress,the prospects and challenges of the modified nickel-rich layer cathodes to upgrade the property of lithium ion batteries are also comprehensively analyzed,and the potential applications in the field of plug-in hybrid vehicles and electric vehicles are further discussed. | Haijian Lv Chunli Li Zhikun Zhao Borong Wu Daobin Mu | 2021 | Journal of Energy Chemistry2021，30，9： | 6 |
| 7 | Assessment of the Transmission Risk of Schistosomiasis after Flooding-North Poyang Lake,Jiangxi Province,China,2020显示文摘What is already known about this topic?Over 90%of Oncomelania snails,the only intermediate host of Schistosoma japonicum,are distributed in the middle and low reaches of Yangtze River.Flooding can extend the distribution of Oncomelania snails and hence accelerate the transmission of schistosomiasis.What is added by this report?Although the dispersal of Oncomelania snails was negligible in north Poyang Lake after flooding in 2020,2 samples of cattle feces with Schistosoma egg and 2 infected snails samples were indeed found.All four risk sites were distributed in Lushan County.Cattle feces were observed in the six out of seven field sites in Lushan County.What are the implications for public health practice?The present national control strategy focusing on control of infection source should be reinforced in Lushan and other schistosomiasis endemic areas.Overlaps of infected snails and cattle feces with Schistosoma egg were not observed,which called for intensive surveillance in Lushan County. | Shan Lv Fan Yang Zhiqiang Qin Chunli Cao Jing Xu Shizhu Li Xiao-nong Zhou | 2021 | China CDC weekly2021，3，5： | 5 |
| 8 | Rapid Assessment on Potential Risks of Schistosomiasis Transmission—7 PLADs,China,2019 and 2021显示文摘Summary What is already known about this topic?Oncomelania hupensis(O.hupensis)and livestock are main infection sources of schistosomiasis.The schistosome infected O.hupensis and livestock’s feces are important risk factors in the transmission of schistosomiasis.What is added by this report?The potential risks of schistosomiasis transmission remain prevalent,giving an early warning to local government with information on existing transmission risks.It is expected that the effectiveness and efficiency of schistosomiasis surveillance could be improved by conducting rapid risk assessment at the beginning of transmission season. | Junyi He Hongqing Zhu Ziping Bao Lijuan Zhang Yinlong Li Ting Feng Suying Guo Wangping Deng Can Wang Hui Dang Tiewu Jia Chao Lyu Zhiqiang Qin Chunli Cao Jing Xu Shizhu Li Xiaonong Zhou | 2021 | China CDC weekly2021，3，51： | 5 |
| 9 | Activin A prevents neuron-like PC12 cell apoptosis after oxygen-glucose deprivation显示文摘In this study, PC12 cells were induced to differentiate into neuron-like cells using nerve growth facto and were subjected to oxygen-glucose deprivation. Cells were treated with 0, 10, 20, 30, 50, 100 ng/mL exogenous Activin A. The 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl tetrazolium bromide assay and Hoechst 33324 staining showed that the survival percentage of PC12 cells significantly decreased and the rate of apoptosis significantly increased after oxygen-glucose deprivation. Exogenous Activin A significantly increased the survival percentage of PC12 cells in a dose-dependent manner. Reverse transcription-PCR results revealed a significant increase in Activin receptor IIA, Smad3 and Smad4 mRNA levels, which are key sites in the Activin A/Smads signaling pathway, in neuron-like cells subjected to oxygen-glucose deprivation, while mRNA expression of the apoptosis-regulation gene caspase-3 decreased. Our experimental findings indicate that exogenous Activin A plays an anti-apoptotic role and protects neurons by means of activating the Activin A/Smads signaling pathway. | Guihua Xu Jinting He Hongliang Guo Chunli Mei Jiaoqi Wang Zhongshu Li Han Chen Jing Mang Hong Yang Zhongxin Xu | 2013 | Neural Regeneration Research2013，8，11： | 5 |
| 10 | Does clopidogrel with aspirin after acute minor stroke or transient ischemic attack increase the risk of cerebral hemorrhage?显示文摘Wang et al1 recently showed that in patients with transient ischemic attack (TIA) or minor stroke that can be treated within 24 hours after the onset of symptoms,the combination of clopidogrel and aspirin was superior to aspirin alone for reducing the risk of stroke in the first 90 days,without increasing the risk of hemorrhage.We report a patient treated with this combination but suffered recurrent stroke and hemorrhage. | Zheng Haiping Chen Chunli Hu Zhiping Yang Li | 2014 | Chinese Medical Journal2014，，18： | 5 |
| 11 | Application of red mud as a basic catalyst for biodiesel production显示文摘Red mud was investigated in triglyceride transesterification with a view to determine its viability as a basic catalyst for use in biodiesel synthesis.The effect of calcination temperature on the structure and activity of red mud catalysts was investigated.It was found that highly active catalyst was obtained by simply drying red mud at 200°C.Utilization of red mud as a catalyst for biodiesel production not only provides a cost-effective and environmentally friendly way of recycling this solid red mud waste,significantly reducing its environmental effects,but also reduces the price of biodiesel to make biodiesel competitive with petroleum diesel. | Qiang Liu Ruirui Xin Chengcheng Li Chunli Xu Jun Yang | 2013 | Journal of Environmental Sciences2013，25，4： | 5 |
| 12 | Nuclear Aurora kinase A switches m^(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4显示文摘Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression,yet how this process is regulated by oncogenic signal remains largely unknown.Here,we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m^(6)A reader YTHDC1 in lung cancer.Nuclear translocation of AURKA is a prerequisite for RNA aberrant splicing,specifically triggering RBM4 splicing from the full isoform(RBM4-FL)to the short isoform(RBM4-S)in a kinase-independent manner. | SiSi Li YangFan Qi JiaChuan Yu YuChao Hao Bin He MengJuan Zhang ZhenWei Dai TongHui Jiang SuYi Li Fang Huang Ning Chen Jing Wang MengYing Yang DaPeng Liang Fan An JinYao Zhao WenJun Fan YuJia Pan ZiQian Deng YuanYuan Luo Tao Guo Fei Peng ZhiJie Hou ChunLi Wang FeiMeng Zheng LingZhi Xu Jie Xu QingPing Wen BiLian Jin Yang Wang Quentin Liu | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 4 |
| 13 | Experimental and simulation of the reactive dividing wall column based on ethyl acetate synthesis显示文摘Reactive dividing wall column(RDWC) is a highly integrated unit which combines reaction distillation(RD) with dividing wall column separation technology into one shell, and it realized the chemical reaction and the separation of multiple product fractions simultaneously. In this paper, the reaction of esterification with acetic acid and ethanol to produce ethyl acetate was used as the research system, experiments and simulations of the RDWC were carried out. This system in the traditional process mostly used the homogeneous catalyst(e.g. sulfuric acid). However, in view of the corrosion of the equipment caused by the acidity of the catalyst, we used the heterogeneous catalysts – iron exchange resins – Amberlyst15 and proposed a novel catalyst loading method. Firstly,the reliability of the model of the simulation was verified by the experimental study on the change of liquid split ratio and reflux ratio. After that, the four-column model was established in Aspen Plus to analyze the effects of the amount of azeotropic agent, reflux ratio and acetic acid concentration. Finally, for a fair comparison, the economic analysis was conducted between traditional RD column and RDWC. The results showed that RDWC can save34.7% of total operating costs and 18.5% of TAC. | Jiangwei Xie Chunli Li Fei Peng Lihui Dong Shuaiming Ma | 2018 | Chinese Journal of Chemical Engineering2018，26，7： | 4 |
| 14 | A review of internally heat integrated distillation column显示文摘The energy consumption of distillation operation determines the amount of energy consumption throughout the chemical separation process. A heat integrated distillation column(HIDiC) could greatly reduce the irreversibility of the distillation process, so it gradually becomes a research hotspot. There are two major techniques for heat integration in HIDiC: internally and externally. This review paper describes the major research aspects of an internally heat integrated distillation column(IHIDiC), including the heat transfer models, various design structures(including the two-column HIDiC, Concentric HIDiC, Shell and tube HIDiC, Plate-fin HIDiC and the Super HIDiC, etc.), experimental research, simulation and optimization, process control research, as well as industrial plants and potential industrial applications. Among them, the heat transfer performance of various structures was analyzed of the various design structures based on experimental research, the effects of different factors(including relative volatility, reflux ratio, compression ratio, etc.) on HIDiC energy consumption or TAC is summarized in the simulation part. The calculation methods of the overall heat transfer coefficient and heat transfer models are summarized. The various optimization algorithms and optimization results of simplified HIDiC are summarized in the optimization part. The research status and the key technical issues in various aspects of HIDiC are summarized in this paper. In order to meet the requirements of industrial energy efficiency,the selection of multi-component separation distillation configurations needs to be considered more diversified,and internal complex coupling relationship of HIDiC needs to be further studied. | Jing Fang Xiaomin Cheng Zhongyang Li Hao Li Chunli Li | 2019 | Chinese Journal of Chemical Engineering2019，27，6： | 4 |
| 15 | Separation process of butanol-butyl acetate-methyl isobutyl ketone system by the analysis to residual curve and the double effect pressure-swing distillation显示文摘The separation of ternary mixture of butanol, butyl acetate, and methyl isobutyl ketone(MIBK) was initially analyzed by the residual curve. In this process, MIBK was chosen as the azeotropic agent during the first step of separation. The optimum mass ratio of extra MIBK was 1.6 in the modified feed stream according to the residual curve. Thus on this condition the top product was butanol-MIBK azeotrope while the bottom product was butyl acetate in the preliminary separation of the mixture. Then the butanol and MIBK azeotrope was separated by the double effect pressureswing distillation with the low pressure column performing at 30 kPa and the atmospheric pressure column at 101 kPa. The optimal operating conditions were then obtained by using Aspen Plus to simulate and optimize the process. The results showed that the mass purities of butanol, butyl acetate, and MIBK were all more than 99% and reached the design requirements. Additionally, compared with the traditional distillation with outside heating, the double effect pressure swing distillation saved the reboiler duty by 48.6% and the condenser duty by 44.6%. | Chunli Li Yuanyuan Song Jing Fang Yang Liu Weiyi Su Yuqi Hu | 2017 | Chinese Journal of Chemical Engineering2017，25，3： | 4 |
| 16 | Dual effects of α-synuclein on neurotoxicity induced by low dosage of rotenone are dependent on exposure time in dopaminergic neuroblastoma cells显示文摘This study was designed to investigate the effects of α-synuclein on toxicity induced by long-term exposure to relatively low concentrations of rotenone.Compared with the control groups,the inhibition of cell viability which overexpressed α-synuclein(SH-SY5Y-Syn) improved after 1 and 2 weeks of rotenone treatment.The complex I activity was greater and the mitochondrial membrane swelling intensity was reduced after 1 and 2 weeks of treatment,which indicated that α-synuclein,at least in part,resists the rotenone-induced oxidative stress.The results indicate that α-synuclein has a dual effect on toxicity of rotenone according to exposure time in human SH-SY5Y cells. | LU LingLing,GU Li,LIANG Yuan,SUN XiaoHong,DUAN ChunLi & YANG Hui Beijing Institute for Neuroscience,Capital Medical University,The Beijing Center of Neural Regeneration and Repairingr,Key Laboratory for Neurodegenerative Disease of the Ministry of Education,Beijing 100069,China | 2010 | Science China(Life Sciences)2010，53，5： | 3 |
| 17 | Environmental pollution by persistent toxic substances and health risk in an industrial area of China显示文摘Soil is an important environmental medium that is closely associated with humans and their health.Despite this,very few studies have measured toxicants in soils,and associated them with health risks in humans.An assessment of health effects from exposure to contaminants in soils surrounding industrial areas of chemical production and storage is important.This article aims at determining pollution characteristics of persistent toxic substances (PTS) in an industrial area in China to unravel the relationship between soil pollution by PTS and human health.One hundred and five soil samples were collected and 742 questionnaires were handed out to residents living in and around an industrial area around Bohai Bay,Tianjin in Northern China.Concentrations of organochlorine pesticides and polycyclic aromatic hydrocarbons (PAHs) were determined in soil.Mann-Whitney U and binary multivariate non-conditional logistic regression models were employed to analyze the relationship between health indicators of local residents and contaminant levels.Odds ratio (OR) and a 95% confidence interval (CI) for health incidences were also calculated.The average concentrations of DDT (73.9 ng/g),HCH (654 ng/g) and PAHs (1225 ng/g) were relatively high in the industrial area.Residents living in the chemical industry parks were exposed to a higher levels of PTS than those living outside the chemical industry parks.This exposure was associated with a higher risk of breast cancer (OR 1.87,95% CI 0.12-30.06),stomach cancer (OR 1.87,95% CI 0.26-13.41),dermatitis (OR 1.72,95% CI 1.05-2.80),gastroenteritis (OR 1.59,95% CI 0.94-2.68),and pneumonia (OR 1.05,95% CI 0.58-1.89). | Jing Li Yonglong Lu Yajuan Shi Tieyu Wang Guang Wang Wei Luo Wentao Jiao Chunli Chen Feng Yan | 2011 | Journal of Environmental Sciences2011，23，8： | 3 |
| 18 | Simulation Optimization and Experimental Study of Cross-Wall Adiabatic Dividing Wall Column Used to Separate Hexane-Heptane-Octane System显示文摘Through separation of the hexane-heptane–octane system in a cross-wall adiabatic dividing wall column, the effects of feed position, side-draw position, liquid split ratio, vapor split ratio and their interactions on the energy consumption were analyzed by Aspen Plus under the constant product purity, and the response surface model for the energy consumption was regressed. Based on the restriction on the optimal operating zone, the comparison of different combinations of surrogate models and optimization methods showed that, the combination of the Kriging model and multi-island genetic algorithm(Kriging-MIGA) had better prediction ability than the combination of the response surface model and partial derivative method(RSM-PD), and RSM-PD had better optimization effect than Kriging-MIGA. With a self-made cross-wall adiabatic dividing wall column, the temperature at measuring points and the energy consumption were measured during experiments, the comparison between measured values and simulated ones demonstrated that the optimized values of variables searched by RSM-PD and Kriging-MIGA could be both used as the optimum technological conditions since the experimental reliability was ensured, with the optimum technological conditions shown below: The feed position is 6, the side-draw position is 7, the combinations of liquid split ratio and vapor split ratio are [0.14, 0.5] and [0.16, 0.52], respectively. RSM-PD and Kriging-MIGA can provide the appropriate optimization methods for the dividing wall column. | Hu Yuqi Fang Jing Li Chunli | 2015 | China Petroleum Processing & Petrochemical Technology2015，17，1： | 3 |
| 19 | Low-strain TiP_(2)O_(7) withthree-dimensionalionchannelsas long-life and high-rate anode material for Mg-ion batteries显示文摘Rechargeable magnesium batteries are identified as a promising next-generation energy storage system,but their development is hindered by the anode−electrolyte−cathode incompatibilities and passivation of magnesium metal anode.To avoid or alleviate these problems,the exploitation of alternative anode materials is a promising choice.Herein,we present titanium pyrophosphate(TiP_(2)O_(7))as anode materials for magnesium-ion batteries(MIBs)and investigate the effect of the crystal phase on its magnesium storage performance.Compared with the me-tastable layered TiP_(2)O_(7),the thermodynamically stable cubic TiP_(2)O_(7) displays a better rate capability of 72 mAh g^(−1) at 5000 mA g^(−1).Moreover,cubic TiP_(2)O_(7) exhibits excellent cycling stability with the capacity of 60 mAh g^(−1) after 5000 cycles at 1000 mA g^(−1),which are better than pre-viously reported Ti-based anode materials for MIBs.In situ X-ray diffraction technology confirms the single-phase magnesiumion inter-calation/deintercalation reaction mechanism of cubic TiP_(2)O_(7) with a low volume change of 3.2%.In addition,the density functional theory calcu-lation results demonstrate that three-dimensional magnesiumion diffu-sion can be allowed in cubic TiP_(2)O_(7) with a low migration energy barrier of 0.62 eV.Our work demonstrates the promise of TiP_(2)O_(7) as high-rate and long-life anode materials for MIBs and may pave the way for further development of MIBs. | Fangyu Xiong Yalong Jiang Li Cheng Ruohan Yu Shuangshuang Tan Chen Tang Chunli Zuo Qinyou An Yunlong Zhao Jean-Jacques Gaumet Liqiang Mai | 2022 | Interdisciplinary Materials2022，1，1： | 3 |
| 20 | Osteoporosis affects both post-yield microdamage accumulation and plasticity degradation in vertebra of ovariectomized rats显示文摘Estrogen withdrawal in postmenopausal women increases bone loss and bone fragility in the vertebra. Bone loss with osteoporosis not only reduces bone mineral density(BMD), but actually alters bone quality, which can be comprehensively represented by bone post-yield behaviors. This study aimed to provide some information as to how osteoporosis induced by estrogen depletion could influence the evolution of post-yield microdamage accumulation and plastic deformation in vertebral bodies. This study also tried to reveal the part of the mechanisms of how estrogen deficiency-induced osteoporosis would increase the bone fracture risk. A rat bilateral ovariectomy(OVX)model was used to induce osteoporosis. Progressive cyclic compression loading was developed for vertebra testing to elucidate the post-yield behaviors. BMD, bone volume fraction, stiffness degradation, and plastic deformation evolution were compared among rats raised for 5 weeks(ovx5w and sham5 w groups) and 35 weeks(ovx35w and sham35 w groups) after sham surgery and OVX. The results showedthat a higher bone loss in vertebral bodies corresponded to lower stiffness and higher plastic deformation. Thus, osteoporosis could increase the vertebral fracture risk probably through microdamage accumulation and plastic deforming degradation. | Siwei Li Guodong Niu Neil X. Dong Xiaodu Wang Zhongjun Liu Chunli Song Huijie Leng | 2017 | Acta Mechanica Sinica2017，33，2： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员