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| 1 | The first all-season sample set for mapping global land cover with Landsat-8 data显示文摘We report the world's first all-season training and validation sample sets for global land cover classification with Landsat-8 data.Prior to this,such samples were only available at a single date primarily from the growing season.It is unknown how much limitation such a single-date sample has to mapping global land cover in other seasons of the year.To answer this question,we selected available Landsat-8 images from four seasons and collected training and validation samples from them.We compared the performances of training samples in different seasons using Random Forest algorithm.We found that the use of training samples from any individual season would result in the best overall classification accuracy when validated by samples in the same season.The global overall accuracy from combined best seasonal results was 67.2% when classifying the 11 Level-1 classes in the Finer Resolution Observation and Monitoring of Global Land Cover(FROM-GLC) classification system.The use of training samples from all seasons(named all-season training sample set hereafter) produced an overall accuracy of 67.0%.We also tested classification within 10° latitude 60° longitude zones using all-season training subsample within each zone and obtained an overall accuracy of 70.2%.This indicates that properly grouped subsamples in space can help improve classification accuracies.All the results in this study seem to suggest that it is possible to use an all-season training sample set to reach global optimality with universal applicability in classifying images acquired at any time of a year for global land cover mapping. | Congcong Li Peng Gong Jie Wang Zhiliang Zhu Gregory S. Biging Cui Yuan Tengyun Hu Haiying Zhang Qi Wang Xuecao Li Xiaoxuan Liu Yidi Xu Jing Guo Caixia Liu Kwame O. Hackman Meinan Zhang Yuqi Cheng Le Yu Jun Yang Huabing Huang Nicholas Clinton | 2017 | Science Bulletin2017，62，7： | 21 |
| 2 | Identification of mecciRNAs and their roles in the mitochondrial entry of proteins显示文摘Mammalian mitochondria have small genomes encoding very limited numbers of proteins.Over one thousand proteins and noncoding RNAs encoded by the nuclear genome must be imported from the cytosol into the mitochondria.Here,we report the identification of hundreds of circular RNAs(mecciRNAs)encoded by the mitochondrial genome.We provide both in vitro and in vivo evidence to show that mecciRNAs facilitate the mitochondrial entry of nuclear-encoded proteins by serving as molecular chaperones in the folding of imported proteins.Known components involved in mitochondrial protein and RNA importation,such as TOM40 and PNPASE,interact with mecciRNAs and regulate protein entry.The expression of mecciRNAs is regulated,and these transcripts are critical for the adaption of mitochondria to physiological conditions and diseases such as stresses and cancers by modulating mitochondrial protein importation.mecciRNAs and their associated physiological roles add categories and functions to the known eukaryotic circular RNAs and shed novel light on the communication between mitochondria and the nucleus. | Xu Liu Xiaolin Wang Jingxin Li Shanshan Hu Yuqi Deng Hao Yin Xichen Bao Qiangfeng Cliff Zhang Geng Wang Baolong Wang Qinghua Shi Ge Shan | 2020 | Science China(Life Sciences)2020，63，10： | 15 |
| 3 | Water quality characteristics and assessment of Yongding New River by improved comprehensive water quality identification index based on game theory显示文摘The Yongding New River is essential for the water supplies of Tianjin.To date,there is no comprehensive report that assesses the year-round water quality of the Yongding New River Main stream.Moreover,little attention has been given to determining a combined weight for improving the traditional comprehensive water quality identification index(ICWQII)by the game theory.Seven water quality parameters were investigated monthly along the main stream of the Yongding New River from May 2018 to April 2019.Organic contaminants and nitrogen pollution were mainly caused by point sources pollution,and the total phosphorus mainly by non-point source pollution.Dramatic spatio-temporal variations of water quality parameters were jointly caused by different pollutant sources and hydrometeorological factors.In terms of this study,an improved comprehensive water quality identification index(ICWQII)based on entropy weight or variation coefficient and traditional CWQII underestimated the water qualities,and an ICWQII based on the superstandard multiple method overvalued the assessments.By contrast,water qualities assessments done with an ICWQII based on the game theory matched perfectly with the practical situation.The ICWQII based on game theory proposed in this study takes into account not only the degree of disorder and variation of water quality data,but also the influence of standard-exceeded pollution indicators,whose results are relatively reasonable.All findings and the ICWQII based on game theory can provide scientific support for decisions related to the water environment management of the Yongding New River and other waters. | Yu Liu Yucheng Hu Yumei Hu Yuqi Gao Zhenying Liu | 2021 | Journal of Environmental Sciences2021，33，6： | 8 |
| 4 | Separation process of butanol-butyl acetate-methyl isobutyl ketone system by the analysis to residual curve and the double effect pressure-swing distillation显示文摘The separation of ternary mixture of butanol, butyl acetate, and methyl isobutyl ketone(MIBK) was initially analyzed by the residual curve. In this process, MIBK was chosen as the azeotropic agent during the first step of separation. The optimum mass ratio of extra MIBK was 1.6 in the modified feed stream according to the residual curve. Thus on this condition the top product was butanol-MIBK azeotrope while the bottom product was butyl acetate in the preliminary separation of the mixture. Then the butanol and MIBK azeotrope was separated by the double effect pressureswing distillation with the low pressure column performing at 30 kPa and the atmospheric pressure column at 101 kPa. The optimal operating conditions were then obtained by using Aspen Plus to simulate and optimize the process. The results showed that the mass purities of butanol, butyl acetate, and MIBK were all more than 99% and reached the design requirements. Additionally, compared with the traditional distillation with outside heating, the double effect pressure swing distillation saved the reboiler duty by 48.6% and the condenser duty by 44.6%. | Chunli Li Yuanyuan Song Jing Fang Yang Liu Weiyi Su Yuqi Hu | 2017 | Chinese Journal of Chemical Engineering2017，25，3： | 4 |
| 5 | Simulation Optimization and Experimental Study of Cross-Wall Adiabatic Dividing Wall Column Used to Separate Hexane-Heptane-Octane System显示文摘Through separation of the hexane-heptane–octane system in a cross-wall adiabatic dividing wall column, the effects of feed position, side-draw position, liquid split ratio, vapor split ratio and their interactions on the energy consumption were analyzed by Aspen Plus under the constant product purity, and the response surface model for the energy consumption was regressed. Based on the restriction on the optimal operating zone, the comparison of different combinations of surrogate models and optimization methods showed that, the combination of the Kriging model and multi-island genetic algorithm(Kriging-MIGA) had better prediction ability than the combination of the response surface model and partial derivative method(RSM-PD), and RSM-PD had better optimization effect than Kriging-MIGA. With a self-made cross-wall adiabatic dividing wall column, the temperature at measuring points and the energy consumption were measured during experiments, the comparison between measured values and simulated ones demonstrated that the optimized values of variables searched by RSM-PD and Kriging-MIGA could be both used as the optimum technological conditions since the experimental reliability was ensured, with the optimum technological conditions shown below: The feed position is 6, the side-draw position is 7, the combinations of liquid split ratio and vapor split ratio are [0.14, 0.5] and [0.16, 0.52], respectively. RSM-PD and Kriging-MIGA can provide the appropriate optimization methods for the dividing wall column. | Hu Yuqi Fang Jing Li Chunli | 2015 | China Petroleum Processing & Petrochemical Technology2015，17，1： | 3 |
| 6 | 雷公藤红素通过靶向核受体Nur77促进损伤线粒体自噬而抑制炎症反应显示文摘文章简介线粒体在细胞死亡、自噬、免疫和炎症中起着不可或缺的作用。前期研究发现,孤儿核受体Nur77通过靶向线粒体诱导细胞凋亡。本文报道了Nur77作为具有抗炎作用的雷公藤红素的直接靶点,介导雷公藤红素通过自噬清除损伤线粒体,抑制炎症反应而达到治疗炎症疾病包括肥胖症的功能。 | Mengjie Hu Qiang Luo Gulimiran Alitongbieke Shuyi Chong Chenting Xu Lei Xie Xiaohui Chen Duo Zhang Yuqi Zhou Zhaokai Wang Xiaohong Ye Lijun Cai Fang Zhang Huibin Chen Fuquan Jiang Hui Fang Shanjun Yang Jie Liu Maria T.Diaz-Meco Ying Su Hu Zhou Jorge Moscat Xiangzhi Lin 张晓坤 | 2018 | 科学新闻2018，0，4： | 3 |
| 7 | FAST SOLUTION FOR LARGE SCALE LINEAR ALGEBRAIC EQUATIONS IN FINITE ELEMENT ANALYSIS显示文摘The computational efficiency of numerical solution of linear algebraic equations in finite elements can be improved in tow wqys. One is to decrease the fill-in numbers, which are new non-ze-ro numbers in the matrix of global stiffness generated during the process of elimination.The other is to reduce the computational operation of multiplying a real number by zero.Based on the fact that the order of elimination can determine how many fill-in numbers should be generated, we present a new method for optimization of numbering nodes. This method is quite different from bandwidth optimization. Fill-in numbers can be decreased in a large scale by the use of this method. The bi-factorization method is adoted to avoid multiplying real numbers by zero.For large scale finite element analysis, the method presented in this paper is more efficient than the traditional LDLT method. | Qi Zhaohui Liu Yuqi Hu Ping | 2001 | Acta Mechanica Solida Sinica2001，14，1： | 3 |
| 8 | Lactate dehydrogenases amplify reactive oxygen species in cancer cells in response to oxidative stimuli显示文摘Previous studies demonstrated that superoxide could initiate and amplify LDH-catalyzed hydrogen peroxide production in aqueous phase,but its physiological relevance is unknown.Here we showed that LDHA and LDHB both exhibited hydrogen peroxide-producing activity,which was significantly enhanced by the superoxide generated from the isolated mitochondria from HeLa cells and patients'cholangiocarcinoma specimen.After LDHA or LDHB were knocked out,hydrogen peroxide produced by Hela or 4T1 cancer cells were significantly reduced.Re-expression of LDHA in LDHA-knockout HeLa cells partially restored hydrogen peroxide production.In HeLa and 4T1 cells,LDHA or LDHB knockout or LDH inhibitor FX11 significantly decreased ROS induction by modulators of the mitochondrial electron transfer chain(antimycin,oligomycin,rotenone),hypoxia,and pharmacological ROS inducers piperlogumine(PL)and phenethyl isothiocyanate(PEITC).Moreover,the tumors formed by LDHA or LDHB knockout HeLa or 4T1 cells exhibited a significantly less oxidative state than those formed by control cells.Collectively,we provide a mechanistic understanding of a link between LDH and cellular hydrogen peroxide production or oxidative stress in cancer cells in vitro and in vivo. | Hao Wu Yuqi Wang Minfeng Ying Chengmeng Jin Jiangtao Li Xun Hu | 2021 | Signal Transduction and Targeted Therapy2021，6，7： | 2 |
| 9 | Shape-controlled synthesis of liquid metal nanodroplets for photothermal therapy显示文摘The capping agents for liquid metal (LM) nanodroplets in aqueous solutions are restricted to thiol-containing and positively-charged molecules or macromolecules.However,both thiolate-metal complex and electrostatic interaction are liable to detachment upon strong mechanical forces such as sonication,leading to limited stability and applications.To address this,we utilized ultrasmall water soluble melanin nanoparticles (MNPs) as the capping agent,which exhibited strong metal binding capability with the oxide layer of gallium based LMs and resulted in enhanced stability.Interestingly,shape-controlled synthesis of LM nanodroplets can be achieved by the incorporation of MNPs.Various EGaln nanostructures including nanorice,nanosphere and nanorod were obtained by simply tuning the feed ratio,sonication time,and suspension temperature.Among these shapes,EGaln nanorice has the best photothermal conversion efficiency,which could be leveraged for photothermal therapy. | Junjie Yan Xudong Zhang Yang Liu Yanqi Ye Jicheng Yu Qian Chen Jinqiang Wang Yuqi Zhang Quanyin Hu Yang Kang Min Yang Zhen Gu | 2019 | Nano Research2019，12，6： | 2 |
| 10 | Optimization of Dividing Wall Column with Heat Transfer Process Across the Wall for Feed Properties Variation显示文摘This paper investigates the thermal-coupled effect across the wall and the optimal heat transfer region of the wall for enhancing the energy saving effect of dividing wall column (DWC), and also studies the effects of feed thermal condition (q) and middle component composition of feed (cB) on the heat transfer process, the optimal heat transfer region, and the maximum heat transfer quantity across the wall. The simulation results show that the maximum heat transfer quantity across the wall and the potential for energy saving increase with the increase of q, while with the limitation of temperature difference across the wall, the beneficial heat transfer effect between certain range of stages, which are involved in the optimal heat transfer region, cannot be realized completely for a specific value of q. Besides, compared with q, a changing cB does not change the degree of realizing the beneficial heat transfer effect, but can bring about the variation of liquid split ratio (RL) and vapor split ratio (Rv). Thus, for achieving a maximum energy-saving effect of DWC, different q and cB need to find its own corresponding suitable heat transfer process across the wall. | Hu Yuqi Li Chunli | 2019 | China Petroleum Processing & Petrochemical Technology2019，21，2： | 2 |
| 11 | Study on the relationship between chromatographic retention behaviour and molecular structure显示文摘 | Feng Yuqi Zhu Pengling Hu Zhide | 1988 | Chromatographia1988，，5： | 2 |
| 12 | Environmental biogeochemical behaviors of rare earth elements in soil–plant systems显示文摘 | Tao Liang Shen Zhang Lijun Wang Hsiang-Te Kung Yuqi Wang Aitang Hu Shiming Ding | 2005 | Environmental Geochemistry and Health2005，，4： | 2 |
| 13 | Traditional Chinese Medicine guidelines for coronavirus disease 2019显示文摘OBJECTIVE:To summarize the evidence from Traditional Chinese Medicine(TCM)practice in the treatment of coronavirus disease 2019(COVID-19)and provide timely clinical practice guidance.METHODS:The guidelines were developed in accordance with the World Health Organization rapid guideline process.The evidence on TCM for COVID-19 from published guidelines,direct and indirect published clinical evidence,first hand clinical data,and expert experience and consensus were collected.The grading of recommendations assessment,development and evaluation(GRADE)method was used to grade the evidence and make the recommendations.RESULTS:Based on the available evidence,the guidelines recommended 17 Chinese medicines for COVID-19:2 Chinese herbal granules,7 Chinese patent medicines,and 8 Chinese herbal injections.CONCLUSION:As the literature search was conducted on March,any subsequent versions of these guidelines require an up-to-date literature review.We hope that the evidence summary in these guidelines will be helpful in global efforts to address COVID-19. | Liang Ning Ma Yanfang Wang Jingya Li Huizhen Wang Xiaohui Jiao Liwen Liu Bin Ma Yan Zhao Chen Luo Xufei Zhao Siya Lu Meng Cao Jin Hu Wenpin Zhang Hairong Liu Guoxiu Lu Cheng Liu Mengyu Li Li Han Xuejie Liu Yuqi Wang Liying Zhao Xueyao Wei Dongfeng Bai Jing Sun Mingyu Yang Yong Wu Xiaodan Chen Yaolong Shi Nannan Wang Yanping Wang Yongyan | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 2 |
| 14 | The influence of the metal net charge of non-metallocene early transition metal catalyst on the ethylene polymerization activity显示文摘The net charges on central metals of a serial non-metallocene early transition metal catalysts (FI catalyst) with similar steric hindrance were caculated with MM-QEq (molecular mechmism-charge equilibration) method and associated with ethylene polymerization activities of these FI catalyts. It was found that the activity increased with the net charge on metal if ignoring the influence of the steric hindrance. In other words, introduction of strong and/or more electron-withdrawing groups onto the ligand of FI catalyst would enhance the activity of the catalyst. This conculsion gave a direction to designing new FI catalyst with higher activity. | WU ChunHong LI HuaYi FENG YuQi HU YouLiang | 2008 | Chinese Science Bulletin2008，53，20： | 1 |
| 15 | Highly efficient production of 2,5-dihydroxymethylfuran from biomass-derived 5-hydroxymethylfurfural over an amorphous and mesoporous zirconium phosphonate catalyst显示文摘The development of high-efficiency and low-cost catalysts is very crucial for the MeerweinPonndorf-Verley (MPV) reduction of biomass-derived 5-hydroxymethylfurfural (HMF) into 2,5-dihydroxymethylfuran (DHMF). In this work, an amorphous and mesoporous zirconium phosphonate catalyst (Zr-DTMP), which is a zirconium-containing organic-inorganic nanohybrid, was successfully designed and synthesized by the simple assembly of zirconium tetrachloride (ZrCl4) and diethylene triaminepenta(methylene phosphonic acid)(DTMP). Satisfactorily, when Zr-DTMP was employed for the MPV reduction of HMF in the presence of 2-butanol (secBuOH), DHMF yield could be achieved as 96.5% in 3 h under a relatively mild reaction temperature of 140℃. Systematic investigations indicated that this high catalytic activity should be mainly due to the cooperative role of enhancive Lewis acid site (Zr4+) and Lewis base site (O2-) in activating the carbonyl group of HMF and dissociating the hydroxyl group of secBuOH, respectively. Additionally, Zr-DTMP showed excellent catalytic stability, when it was successively used 5 recycles, its surface characteristics and textural properties still remained almost unchanged, and so, the catalytic activity was not obviously affected. More interestingly, Zr-DTMP could also be applied for the selective reduction of other biomass-derived carbonyl compounds, such as 5-methylfurfural (MF), furfural (FF), levulinic acid (LA), ethyl levulinate (EL) and cyclohexanone (CHN), into the corresponding products with high yields, which is beneficial to the effective synthesis of various valuable bio-based chemicals. | Lei Hu Ning Li Xiaoli Dai Yuqi Guo Yetao Jiang Aiyong He Jiaxing Xu | 2019 | Journal of Energy Chemistry2019，28，10： | 1 |
| 16 | Evaluation intersys- tern interference between compass and Galileo显示文摘 | Hang R Y Liu Yuqi Hu Xiulin | 2011 | Journal of Convergence Information Technology2011，6，6： | 1 |
| 17 | A review of the methods used for subjective evaluation of De Qi显示文摘De Qi refers to a series of sensations experienced when acupuncture is performed at acupoints. De Qi comprises needling sensations felt by the patient, and the sensations perceived by the acupuncturist. Classical Traditional Chinese Medicine theory states that De Qi is closely related to curative effect.In modern studies, the main index that researchers have used to evaluate De Qi was the needling sensation reported by the patient. Between 1 st Aug and 31 st Oct 2014, we conducted an electronic database search of all fields in Chinese and English to select literature assessing acupuncture needle sensations. We then reviewed the methods used within these studies to evaluate De Qi. The methods included simple evaluation, and the use of a De Qi scale/questionnaire. The simple evaluation, a qualitative evaluation, was judged by typical sensations felt by the patient after needling at acupoints, such as soreness, numbness, fullness, and heaviness.This method was easy and practicable, and had been adopted widely by Chinese researchers. In contrast, the De Qi scale/questionnaire, a quantitative evaluation, had multiple compiling methods available for evaluating the intensity of De Qi. The standardization and objectification of the De Qi scale/questionnaire effectively improved the quality of studies on De Qi, thereby these scales/questionnaires have been acknowledged and applied by most researchers. The present review analyzed and compared the scales/questionnaires used to evaluate De Qi; furthermore, we provided suggestions for the development and improvement of these questionnaires through integration with classical De Qi theory. | Yuan Hongwen Wang Pei Hu Nijuan Zhang Peng Li Chunhua Liu Yuqi Ma Liangxiao Zhu Jiang | 2018 | Journal of Traditional Chinese Medicine2018，38，2： | 1 |
| 18 | Profiling of Permeable Compounds in Ligusticum chuanxiong by Biopartitioning Micellar Chromatography显示文摘 | Zhixiong Hu Weinong Zhang Haibo He Yuqi Feng Shilu Da | 2009 | Chromatographia (-)2009，，7： | 1 |
| 19 | 内侧缰核胆碱能神经元GABAB受体通过突触前兴奋作用调控动物恐惧记忆显示文摘动物的生存依赖于将预警信号和危险联系起来.对预警信号形成恐惧记忆,以便提前做出反应。当预警信号不再与危险相关时,动物逐渐解除这种联系,消退恐惧记忆,以适应新的生存环境。恐惧记忆消退缺陷被认为和人类创伤后应激障碍(PTSD)等精神障碍有紧密关系。目前关于动物恐惧记忆的研究主要集中在杏仁核及其相关脑区。 | 张举恩 Lubin Tan Yuqi Ren Jingwen Liang Rui Lin Qiru Feng Jingfeng Zhou Fei Hu Jing Ren Chao Wei Tao Yu Yinghua Zhuang Bernhard Bettler Fengchao Wang 罗敏敏 | 2017 | 科学新闻2017，19，4： | 1 |
| 20 | Energy-saving mechanism in heat transfer optimization of dividing wall cotunm 显示文摘 | Fang Jing Hu Yuqi Li Chunli | 2013 | Ind Eng Chem Res2013，52，18： | 1 |
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