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| 1 | The Lushan M_S7.0 earthquake and activity of the southern segment of the Longmenshan fault zone显示文摘Following the Lushan MS7.0 earthquake on 20 April 2013,a topic of much concern is whether events of MS7 or greater could occur again on the southern segment of the Longmenshan fault zone.In providing evidence to answer this question,this work analyzes the tectonic relationship between the Lushan event and the 2008 Wenchuan earthquake and the rupture history of the southern segment of the Longmenshan fault zone,through field investigations of active tectonics and paleoearthquake research,and our preliminary conclusions are as follows.The activity of the southern segment of the Longmenshan fault zone is much different to that of its central section,and the late Quaternary activity has propagated forward to the basin in the east.The seismogenic structure of the 2008 Wenchuan earthquake is the central-fore-range fault system,whereas that of the 2013 Lushan event is attributed to the fore-range-range-front fault system,rather than the central fault.The southern segment of the Longmenshan fault zone becomes wider towards the south with an increasing number of secondary faults,of which the individual faults exhibit much weaker surface activity.Therefore,this section is not as capable of generating a major earthquake as is the central segment.It is most likely that the 2013 earthquake fills the seismic gap around Lushan on the southern segment of the Longmenshan fault zone. | CHEN LiChun RAN YongKang WANG Hu LI YanBao MA XinQuan | 2013 | Chinese Science Bulletin2013，58，28： | 24 |
| 2 | Large scale patterns of forage yield and quality across Chinese grasslands显示文摘Understanding the patterns of forage quantity and quality and investigating the factors influencing these patterns are essential for the development of animal husbandry.However,there is very little field evidence focused on these issues at a large spatial scale.In the current study,we analyzed forage quantity and quality at 177 sites distributed in all the major grassland types across China,and explored the relationship between forage quantity and quality based on consistent sampling protocols.We also investigated potential factors influencing forage quality patterns across China.Our study indicates the Tibetan grasslands had both higher quantity and quality forage than the Inner Mongolian grasslands,and alpine meadow had the best quantity and quality forage because of the meadow's high productivity and the crude protein and nitrogen free extract content of the meadow forage.For the main vegetation formations,Kobresia tibetica meadows and Achnatherum splendens steppes had the highest quantity,while Kobresia pygmaea meadows and Kobresia humilis meadows had the best quality.We also found that although environmental factors,such as temperature and soil fertility,could affect physiological processes and so influence forage quality,the large scale patterns of change were mainly a result of the differences in vegetation types.Finally,we reported a negative relationship between forage quantity and quality:higher forage quantity means more crude fiber but less ether extract and crude protein.These findings improve our understanding on the spatial patterns of forage quantity and quality,and provide solid evidence related to the future development of animal husbandry. | SHI Yue MA YinLei MA WenHong LIANG CunZhu ZHAO XinQuan FANG JingYun HE JinSheng | 2013 | Chinese Science Bulletin2013，58，10： | 12 |
| 3 | Reversible and irreversible heat generation of NCA/Si–C pouch cell during electrochemical energy-storage process显示文摘To meet the requirements of electronic vehicles(EVs) and hybrid electric vehicles(HEVs),the high energy density Li Ni_(0.8) Co_(0.15) Al_(0.05) O_2(NCA) cathode and Si–C anode have attracted more attention.Here we report the thermal behaviors of NCA/Si–C pouch cell during the charge/discharge processes at different current densities.The total heat generations are derived from the surface temperature change during electrochemical Li+insertion/extraction in adiabatic surrounding.The reversible heat is determined by the entropic coefficients,which are related with open-circuit voltage at different temperatures; while the irreversible heat is determined by the internal resistance,which can be obtained via V–I characteristic,electrochemical impedance spectroscopy and hybrid pulse power characterization(HPPC).During the electrochemical process,the reversible heat contributes less than 10% to total heat generation; and the heat generated in charge process is less than that in discharge process.The results of thermal behaviors analyses are conducive to understanding the safety management and paving the way for building a reliable thermal model of high energy density lithium ion battery. | Ying Bai Limin Li Yu Li Guanghai Chen Huichun Zhao Zhaohua Wang Chuan Wu Hongyun Ma Xinquan Wang Hongyue Cui Jiang Zhou | 2019 | Journal of Energy Chemistry2019，28，2： | 7 |
| 4 | Late Quaternary Large Earthquakes on the Western Branch of the Xiaojiang Fault and Their Tectonic Implications显示文摘Xiaojiang 差错是沿着西藏的高原的东南的边缘的一个主要活跃左侧面的差错。在云南省的最大的历史的地震,与大小 8 并且吝啬的 coseismic ∼ 的左侧面的排水量 6.9 m,发生在学习这个差错的 Xiaojiang 差错的西方的分支上在理解当前的变丑和西藏的高原的运动学的特征是重要的。活动和段很好在 Xiaojiang 差错上被承担了,当 paleoseismic 研究工作总是是这个差错上的弱连接时。为了调查 paleoseismic 历史和 Xiaojiang 的大地震活动,指责,我们在 Caohaizi 的北边打开了一条大沟下垂 Xiaojiang 差错的西方的分支上的池溏。六个 paleoseismic 事件通过 E6 被鉴别了,并且称为 E1 从对最年轻的炭和森林最旧是丰富的 20 件样品被标明日期在 40 000-36 抑制 paleoseismic 事件的年龄 300 BC , 35 400-24 800 BC , 9 500 BC广告 500 ,广告 390-720 ,广告 1120-1620 和广告1750礼品我们把最年轻的事件 E6 与 1833 M8 地震联系。事件 E4, E5 和 E6 在迟了的 Holocene 显示出 Xiaojiang 差错的西方的海滨的一个连续记录,与 370-480 年的平均复发间隔。在迟了的 Holocene 的大地震复发是远的不到 2000-4000 年的复发在以前的研究摆姿势。因此, Xiaojiang 差错上的地震危险应该被重新估计。而且, Xiaojiang 差错和其它上的大地震的不规则的复发在 Xianshuihe-Xiaojiang 系统指责,沿着西藏的高原的东南的边缘显示四川云南块的不平的向东南的挤出。 | LI Xi RAN Yongkang CHEN Lichun WU Fuyao MA Xinquan CAO Jun | 2015 | Acta Geologica Sinica(English Edition)2015，89，5： | 7 |
| 5 | Offering the win-win solutions between ecological conservation and livelihood development:National parks in Qinghai, China显示文摘National parks as protected areas have been on the spotlight because they are essential in achieving ecological civilization in China.Despite the profound achievements of national parks to conserve nature,the benefits of national parks for local residents remain lacking.Under the theory of harmonious coexistence between human and nature,this study focused on the development of local people’s livelihood in Qinghai’s national parks.We systematically explored the establishment of the national parks in Qinghai Province,analyzed the current prob-lems,and provided the main measures for developing people’s livelihood in protected areas in Qinghai.This study put forward the viewpoint that national parks should set a long-term goal,and gradually advance based on the environmental conditions and appropriately prioritize the improvement of local people’s wellbeing in the future. | Qi Cheng Xue Cheng Kexin Ma Xinquan Zhao Jiapeng Qu | 2020 | Geography and Sustainability2020，1，4： | 3 |
| 6 | Therapeutic safety evaluation of sodium glycididazole combined with ^(131)I radiotherapy for differentiated thyroid carcinoma显示文摘To evaluate safety and therapeutic efficacy of sodium glycididazole (CMNa) combined with 131I radiotherapy for differentiated thyroid carcinoma (DTC),the 60 patients of DTC therapeutic protocols were selected and divided into 3 groups of the DTC 4.44 GBq 131I,DTC 3.70 GBq 131I,and combination of DTC 3.70 GBq 131I with CMNa,and the 20 patients of Graves' Disease were selected as the control group.Peripheral blood was sampled at 131I pre-treatment of 1 day,and 131I post-treatment of 7,91,and 182 days,thus analyzing lymphocyte micronucleus scores and karyotyping profiles.Compared with the control group,the lymphocyte micronucleus and chromosome mutation rates in 131I treated DTC increased after post-treatment of 7 days,recovered after post-treatment of 91 days,and did not bounce after post-treatment of 182 days.The micronucleus and chromosome mutation rates in the combination of DTC 3.70 GBq 131I with CMNa showed less significant variation than other treated DTC groups.Our results demonstrate that micronucleus assay and karyotyping analysis are favorable to evaluate 131I radiotherapy for DTC.The combination of the CMNa with 131I radiotherapy was safe for DTC patients without affecting the long-term therapeutic outcomes. | SUN Wenwei GU Xinquan GAO Shi BAI Lin CUI Qu MA Qingjie Wang Qing Zhao Guoqing | 2011 | Nuclear Science and Techniques2011，22，4： | 0 |
| 7 | YTHDF2-mediated regulations bifurcate BHPF-induced programmed cell deaths显示文摘N6-methyladenosine(m^(6)A)is a critical regulator in the fate of RNA,but whether and how m^(6)A executes its functions in different tissues remains largely obscure.Here we report downregulation of a crucial m^(6)A reader,YTHDF2,leading to tissue-specific programmed cell deaths(PCDs)upon fluorene-9-bisphenol(BHPF)exposure.Currently,Bisphenol A(BPA)substitutes are widely used in plastic manufacturing.Interrogating eight common BPA substitutes,we detected BHPF in 14%serum samples of pregnant participants.In a zebrafish model,BHPF caused tissue-specific PCDs triggering cardiac and vascular defects.Mechanistically,BHPF-mediated downregulation of YTHDF2 reduced YTHDF2-facilitated translation of m^(6)A-gch1 for cardiomyocyte ferroptosis,and decreased YTHDF2-mediated m^(6)A-sting1 decay for caudal vein plexus(CVP)apoptosis.The two distinct YTHDF2-mediated m^(6)A regulations and context-dependent co-expression patterns of gch1/ythdf2 and tnfrsf1a/ythdf2 contributed to YTHDF2-mediated tissue-specific PCDs,uncovering a new layer of PCD regulation.Since BHPF/YTHDF2-medaited PCD defects were also observed in mammals,BHPF exposure represents a potential health threat. | Jiebo Lin Guankai Zhan Jinfeng Liu Yasen Maimaitiyiming Zhiping Deng Baohua Li Kunhui Su Jiafeng Chen Siqi Sun Wanlin Zheng Xianghui Yu Feng He Xiaodong Cheng Lingfang Wang Bin Shen Ziqin Yao Xinquan Yang Jian Zhang Wentao He Hengyu Wu Hua Naranmandura Kao-Jung Chang Junxia Min Jun Ma Mikael Björklund Peng-Fei Xu Fudi Wang Chih-Hung Hsu | 2023 | National Science Review2023，10，12： | 0 |
| 8 | Metabolic profile analysis based on GC-TOF/MS and HPLC reveals the negative correlation between catechins and fatty acids in the cottonseed of Gossypium hirsutum显示文摘Background: The diversified and high value-added utilization of cotton by products can promote the sustainable development of modern agriculture. Di erences in potential nutrients among varieties can be explained by variations in the composition and abundance of fatty acids, polyphenols, carbohydrates, amino acids, and organic acids. Therefore, the analysis of metabolite species and relationships in cottonseed is meaningful for the development of cotton byproducts.Results: In this study, the metabolomes of three representative cotton cultivars of di erent species were compared using untargeted GC-TOF/MS analysis. A total of 263 metabolites were identified from 705 peaks, and their levels were compared across cultivars. Principal component analysis and OPLS-DA clearly distinguish these samples based on metabolites. There were significant di erences in the contents of amino acids, carbohydrates, organic acids, flavonoids, and lipids in G. hirsutum TM-1 compared with G. arboreum Shixiya1 and G. barbadense Hai7124. Notably, the bioactive nutrient compound catechin obtained from the di erential metabolites significantly accumulated in TM-1. Furthermore, a comprehensive analysis using catechin and oil-related traits was conducted in core collections of Gossypium hirsutum. The results revealed the reliability of the GC-TOF/MS analysis, as well as that catechin content has a negative association with myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, arachidic acid, and total fatty acids.Conclusion: These findings suggest that untargeted GC-TOF/MS analysis could provide a new method for investigating the underlying plant biochemistry of nutrient variation in cottonseed, and that catechin content has a negative association with oil-related traits in cottonseed. This study may pave the way to exploit the value of cotton byproducts. | MA Lei CHEN Yabing XU Shuangjiao DONG Ruidan WANG Yiwen FANG Dan PENG Jun TIAN Xinquan | 2022 | Journal of Cotton Research2022，5，2： | 0 |
| 9 | RUP2 facilitates UVR8 redimerization via two interfaces显示文摘The plant UV-B photoreceptor UV RESISTANCE LOCUS 8(UVR8)exists as a homodimer in its inactive ground state.Upon UV-B exposure,UVR8monomerizes and interacts with a downstreamkey regulator,theCONSTITUTIVE PHOTOMORPHOGENIC 1/SUPPRESSOR OF PHYA(COP1/SPA)E3 ubiquitin ligase complex,to initiate UV-B signaling.Two WD40 proteins,REPRESSOR OF UV-B PHOTOMORPHOGENESIS 1(RUP1)and RUP2 directly interact with monomeric UVR8 and facilitate UVR8 ground state reversion,completing the UVR8 photocycle.Here,we reconstituted the RUP-mediated UVR8 redimerization process in vitro and reported the structure of the RUP2-UVR8^(W285A) complex(2.0A).RUP2 and UVR8^(W285A) formed a heterodimer via two distinct interfaces,designated Interface 1 and 2.The previously characterized Interface 1 is found between the RUP2 WD40 domain and the UVR8 C27 subregion.The newly identified Interface 2 is formed through interactions between the RUP2 WD40 domain and the UVR8 core domain.Disruption of Interface 2 impairedUV-B induced photomorphogenic development in Arabidopsis thaliana.Further biochemical analysis indicated that both interfaces are important for RUP2-UVR8 interactions and RUP2-mediated facilitation of UVR8 redimerization.Our findings suggest that the two-interface-interaction mode is adopted by both RUP2 and COP1 when they interact with UVR8,marking a step forward in understanding the molecular basis that underpins the interactions between UVR8 and its photocycle regulators. | Lixia Wang Yidong Wang Hongfei Chang Hui Ren Xinquan Wu Jia Wen Zeyuan Guan Ling Ma Liang Qiu Junjie Yan Delin Zhang Xi Huang Ping Yin | 2023 | Plant Communications2023，4，1： | 0 |
| 10 | Cultivation of Innovation Ability of Students in the Discipline of Food Science and Engineering from the Perspective of Engineering Professional Certification显示文摘Cultivating the top-notch innovative talents is an essential task for connotative construction of higher education.As an applicationoriented discipline,the Discipline of Food Science and Engineering attaches great importance to the cultivation of innovation ability of college students.For a long time,however,the discipline education has problems of the inverted teaching subject position,weak coordination ability and single practice mode.The support for the cultivation of innovation ability is weak and ineffective.Therefore,in the context of professional certification of engineering education,it is necessary to make reform of traditional education mode and improve the carrier support and target acquisition taking the Outcomes-based Education(OBE)as guide,the innovation ability cultivation as objective,to provide effective guarantee for cultivation of the top-notch talents.These have become issues that should not be ignored in the development of the Discipline of Food Science and Engineering. | Weijie ZHANG Haile MA Xinquan SONG | 2017 | Asian Agricultural Research2017，9，2： | 0 |
| 11 | Hippocampal mitochondrial cytochrome C oxidase activity and gene expression in a rat model of chronic cerebral ischemia显示文摘The present study established a rat model of chronic cerebral ischemia using bilateral common carotid artery permanent ligation to analyze cytochrome C oxidase activity and mRNA expression in hippocampal mitochondria. Results showed significantly decreased cytochrome C oxidase activity and cytochrome C oxidase II mRNA expression with prolonged ischemia time. Further analysis re-vealed five mitochondrial cytochrome C oxidase II gene mutations, two newly generated mutations, and four absent mutational sites at 1 month after cerebral ischemia, as well as three mitochondrial cytochrome C oxidase III gene mutations, including two newly generating mutations, and one dis-appeared mutational site at 1 month after cerebral ischemia. Results demonstrated that decreased cytochrome C oxidase gene expression and mutations, as well as decreased cytochrome C oxidase activity, resulting in energy dysmetabolism, which has been shown to be involved in the pathological process of ischemic brain injury. | Qing Zhao Yingli Zhang Mingming Zhao Yu Wang Ming Ma Xinquan Gu Xia Cao | 2011 | Neural Regeneration Research2011，6，32： | 0 |
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