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    题名 作者 年代 出处 被引量
1Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia 2003Gastroenterology2003,,6:3
2Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia 2003Gastroenterology2003,,6:2
3Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life.Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant 2022World Journal of Diabetes2022,13,3:2
4Therapeutic efficiency of everolimus and lapatinib in xenograft model of human colorectal carcinoma with KRAS mutation显示文摘Céline Chu Marie‐Sophie No?l‐Hudson Valérie Boige Diane Goéré Sylvie Marion Mélanie Polrot Ludovic Bigot Patrick Gonin Robert Farinotti Laurence Bonhomme‐Faivre 2013Fundamental & Clinical Pharmacology2013,,4:2
5The relation of diabetes to the severity of acute myocardial infarction and post-myocardial infarction survival in Mexica-Americans and non-Hispanic Whites显示文摘 David C Mary L 1994Diabetes1994,43,:1
6Enhanced lysis activity of cytokine induced killer cells against multiple myeloma cells after co-culture with idiotype-pulsed dendritic cells 显示文摘Angena M Sabing R Marie L T 2001Haematologica2001,86,10:1
7Maternal antibody inhibits both cellular and humoral immunity in response to measles vaccination at hirth显示文摘Mary P L Gregory H Paul R 2006Virology2006,350,2:1
8Circadian rhythm disrup-tion in chronic fatigue syndrome 显示文摘David R Bonsal L Mary E 2013Advances in Neuroimmune Biology2013,4,4:1
9Suppression of microR- NA - silencing pathway by HIV - 1 during virus replication 显示文摘TRIBOULET R MARI B LIN Y L 2007Science2007,315,5818:1
10Suppression of microRNA-silencing pathway by HIV-1 during virus replication显示文摘Triboulet R Mari B Lin Y L 2007Science2007,315,15:1
11Suppression of microRNA silencing path way by HIV-1 during virus replication显示文摘Triboulet R Mari B Lin Y L 0,,5818:1
12Aircraft structural morphing using tendon-actuated compliant cellular trusses显示文摘Deepak S R George A L Mary F 2005Journal of Aircraft2005,42,6:1
13Spinal fracture throgh the neurocentral synchondrosis in battered children:a report for three cases显示文摘Vialle R Mary P Schmider L 2006Spine2006,31,11:1
14Hematopoietic cell transplantation (HCT)-specific comorbidity index:a new tool for risk assessment before allogeneic HCT显示文摘Sorror M L Maris M B Storb R 2005Blood2005,106,:1
15Cereulide food toxin,beta cell function and diabetes:facts and hypotheses显示文摘Vangoitsenhoven R Maris M Overbergh L 2015Diabetes Res Clin Pract2015,109,1:1
16High-resolution analysis of chromosomal breakpoints and genomic instability identifies PTPRD as a candidate tumor suppressor gene in neuroblastoma显示文摘Stallings R L Nair P Maris J M 2006Cancer Res2006,66,7:1
17The Design and Validation of a Hybrid Information System for the Auditor's Going Concern Decision 显示文摘Mary J L Gregory R M Pervaiz A 1998Journal of Management Information Systems1998,14,4:1
18CRT modulates capacitative Ca2+ influx by controlling the extent of inositol 1,4, 5-Tisphosphate-induced Caz+ store depletion显示文摘WEN X FRANK J L MARY R W 2000Biol Chem2000,275,36:1
19A model for R&D performance measurement显示文摘Lazzarotti V Manzini R Mari L 2011International Journal of Production Economics2011,134,1:1
20Dual Role of CCR2 in the Constitution and the Resolution of Liver Fibrosis in Mice显示文摘Claudia Mitchell Dominique Couton Jean-Pierre Couty Marie Anson Anne-Marie Crain Vinciane Bizet Laurent Rénia Stanislas Pol Vincent Mallet Hélène Gilgenkrantz 2009The American Journal of Pathology2009,,5:1
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