|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Diagnosis of subepithelial tumors in the upper gastrointestinal tract by endoscopic ultrasonography显示文摘Endoscopic ultrasonography(EUS) is the most accurate procedure for detecting and diagnosing subepithelial tumors,due to its higher sensitivity and specificity than other imaging modalities.EUS can characterize lesions by providing information on echogenic origin,size,borders,homogeneity,and the presence of echogenic or anechoic foci.Linear echoendoscopes,and recently also electronic radial echoendoscopes,can be used with color Doppler or power Doppler to assess the vascular signals from subepithelial masses,and thus permit the differentiation of vascular structures from cysts,as well as the assessment of the tumor blood supply.However,the diagnostic accuracy of EUS imaging alone has been shown to be low in subepithelial lesions with 3rd and 4th layers.It is also difficult to differentiate exactly between benign and malignant tumors and to gain an accurate picture of histology using EUS.On the other hands,EUS guided fine needle aspiration(EUS-FNA) can provide samples for cytologic or histologic analysis.Hypoechoic lesions of the 3rd and the 4th EUS layers,more than in 1 cm diameter are recommended,and histologic confirmation using endoscopic submucosal resection or EUSFNA should be obtained when possible.Therefore,EUSFNA plays an important role in the clinical management of subepithelial tumors.Furthermore improvements in endoscopic technology are expected to be more useful modalities in differential diagnosis and discrimination between benign and malignant subepithelial | Hiroki Sakamoto Masayuki Kitano Masatoshi Kudo | 2010 | World Journal of Radiology2010，2，8： | 40 |
| 2 | Diagnosis of pancreatic tumors by endoscopic ultrasonography显示文摘Pancreatic tumors are highly diverse, as they can be solid or cystic, and benign or malignant. Since their imaging features overlap considerably, it is often difficult to characterize these tumors. In addition, small pancreatic tumors, especially those less than 2 cm in diameter, are difficult to detect and diagnose. For characterizing pancreatic tumors and detecting small pancreatic tumors, endoscopic ultrasonography (EUS) is the most sensitive of the imaging procedures currently available. This technique also provides good results in terms of the preoperative staging of pancreatic tumors. EUS-guided fine needle aspiration (EUS-FNA) has also proved to be a safe and useful method for tissue sampling of pancreatic tumors. Despite these advantages, however, it is still difficult to differentiate between be-nign and malignant, solid or cystic pancreatic tumors, malignant neoplasms, and chronic pancreatitis using EUS, even when EUS-FNA is performed. Recently, contrast-enhanced EUS with Doppler mode (CE-EUS) employing ultrasound contrast agents, which indicate vascularization in pancreatic lesions, has been found to be useful in the differential diagnosis of pancreatic tumors, especially small pancreatic tumors. However, Doppler ultrasonography with contrast-enhancement has several limitations, including blooming artifacts, poor spatial resolution, and low sensitivity to slow flow. Consequently, an echoendoscope was developed recently that has a broad-band transducer and an imaging mode that was designed specifically for contrastenhanced harmonic EUS (CEH-EUS) with a secondgeneration ultrasound contrast agent. The CEH-EUS technique is expected to improve the differential diagnosis of pancreatic disease in the future. This review describes the EUS appearances of common solid and cystic pancreatic masses, the diagnostic accuracy of EUS-FNA, and the relative efficacies and advantages of CE-EUS and CEH-EUS along with their relative advantages and their complementary roles in clinical practice. | Hiroki Sakamoto Masayuki Kitano Ken Kamata Muhammad El-Masry Masatoshi Kudo | 2010 | World Journal of Radiology2010，2，4： | 11 |
| 3 | Stratifying the risk of lymph node metastasis in undifferentiated-type early gastric cancer显示文摘AIM:To study how lymph node metastasis(LNM) risk is stratified in undifferentiated-type early gastric cancer(undiff-EGC) dependent on combinations of risk factors.METHODS:Five hundred and sixty-seven cases with undiff-EGC undergoing gastrectomy with lymphadenectomy were examined retrospectively.Using clinicopathological factors of patient age,location,size,an endoscopic macroscopic tumor form,ulceration,depth,histology,lymphatic involvement(LI) and venous involvement(VI),LNM risk was examined and stratified by conventional statistical analysis and datamining analysis.RESULTS:LNM was positive in 44 of 567 cases(7.8%).Univariate analysis revealed > 2 cm,protrusion,submucosal(sm),mixed type,LI and VI as significant prognostic factors and > 2 cm and LI-positive were independent factors by multivariate analysis.In preoperatively evaluable factors excluding LVI,sm and > 2 cm were independent factors.According to the depth and size,cases were categorized into the low-risk group [m and ≤ 2 cm,0%(LNM incidence)],the moderaterisk group(m and > 2 cm,5.6%; and sm and ≤ 2 cm,6.0%),and the high-risk group(sm and > 2 cm,19.3%).On the other hand,LNM occurred in 1.4% in all LI-negative cases,greatly lower than 28.2% in all LI-positive cases,and LNM incidence was low in LInegative cases even in the moderate- and high-risk groups.CONCLUSION:LNM-related factors in undiff-EGC were depth and size preoperatively while those were LI and size postoperatively.Among these factors,LI was the most significantly correlated factor. | Yukiko Asakawa Masahiko Ohtaka Shinya Maekawa Mitsuharu Fukasawa Yasuhiro Nakayama Tatsuya Yamaguchi Taisuke Inoue Tomoyoshi Uetake Minoru Sakamoto Tadashi Sato Yoshihiko Kawaguchi Hideki Fujii Kunio Mochizuki Masao Hada Toshio Oyama Tomotaka Yasumura Kosaku Omata Atsushi Nishiyama Keiichi Naito Hideo Hata Yoshiaki Haba Kazuyuki Miyata Haruhisa Saitoh Yoichi Yamadera Kazuo Miura Akira Kawaoi Tohru Abe Hajime Tsunoda Yuji Honda Masayuki Kurosaki Nobuyuki Enomoto | 2015 | World Journal of Gastroenterology2015，21，9： | 8 |
| 4 | Contrast-enhanced harmonic endoscopic ultrasonography for assessment of lymph node metastases in pancreatobiliary carcinoma显示文摘AIM: To assess the usefulness of contrast-enhanced harmonic endoscopic ultrasonography(CH-EUS) for lymph node metastasis in pancreatobiliary carcinoma.METHODS: All patients suspected of pancreatobiliary carcinoma with visible lymph nodes after standard EUS between June, 2009 and January, 2012 were enrolled.In the primary analysis, patients with successful EUSfine needle aspiration(FNA) were included. The lymph nodes were assessed by several standard EUS variables(short and long axis lengths, shape, edge characteristic and echogenicity), color Doppler EUS variable [central intranodal blood vessel(CIV) presence] and CH-EUS variable(heterogeneous/homogeneous enhancement patterns). The diagnostic accuracy relative to EUSFNA was calculated. In the second analysis, N-stage diagnostic accuracy of CH-EUS was compared with EUS-FNA in patients who underwent surgical resection.RESULTS: One hundred and nine patients(143 lymph nodes) fulfilled the criteria. The short axis cutoff ≥ 13 mm predicted malignancy with a sensitivity and specificity of 72% and 85%, respectively. These values were 72% and 63% for the long axis cut-off ≥ 20 mm, 62% and 75% for the round shape variable, 81% and 30% for the sharp edge variable, 66% and 61% for the hypoechogenicity variable, 70% and 72% for the CIV-absent variable, and 83% and 91% for the heterogeneous CH-EUS-enhancement variable, respectively. CH-EUS was more accurate than standard and color Doppler EUS, except the short axis cut-off. Notably, three patients excluded because of EUS-FNA failure were correctly N-staged by CH-EUS.CONCLUSION: CH-EUS complements standard and color Doppler EUS and EUS-FNA for assessment of lymph node metastases. | Takeshi Miyata Masayuki Kitano Shunsuke Omoto Kumpei Kadosaka Ken Kamata Hajime Imai Hiroki Sakamoto Naoshi Nisida Yogesh Harwani Takamichi Murakami Yoshifumi Takeyama Yasutaka Chiba Masatoshi Kudo | 2016 | World Journal of Gastroenterology2016，22，12： | 7 |
| 5 | Small invasive ductal carcinoma of the pancreas distinct from branch duct intraductal papillary mucinous neoplasm显示文摘Endoscopic ultrasonography(EUS)is a highly sensitive diagnostic method for the detection of small pancreatic carcinomas.Recently,there have been some reports describing the utility of contrast-enhanced harmonic EUS(CEH-EUS)which uses sonographic contrast agent for differentiation of a pancreatic mass.This report describes a case of small adenocarcinoma of the pancreas distinct from branch duct intraductal papillary mucinous neoplasm(IPMN)in which investigation by EUS took place every 6 mo and diagnosis was made accurately by additional CEH-EUS during the follow- up of the branch duct IPMN.A 68-year-old female was admitted to our hospital because of a branch duct IPMN in the pancreatic body.She had been followedup by EUS every 6 mo.However,after 2 years EUSdemonstrated a low echoic area distinct from the branch duct IPMN which was vaguely discernible by EUS,and accurate sizing and differential diagnosis were considered difficult on the EUS imaging.CHEUS with Sonazoid revealed a hypovascular tumor and we suspected small pancreatic carcinoma.The histopathological diagnosis was adenocarcinoma (10 mm)in the pancreatic tail,distinct from the branch duct IPMN of the pancreatic body.EUS and CEH-EUS may play an important role in the correct diagnosis of small pancreatic tumors,including synchronous and metachronous occurrence of IPMN and ductal adenocarcinoma of the pancreas. | Hiroki Sakamoto Masayuki Kitano Takamitsu Komaki Hajime Imai Ken Kamata Masatomo Kimura Yoshifumi Takeyama Masatoshi Kudo | 2009 | World Journal of Gastroenterology2009，15，43： | 2 |
| 6 | Characterization of intra-abdominal lesions of undetermined origin by contrast-enhanced harmonic EUS (with videos)显示文摘 | Yu Xia Masayuki Kitano Masatoshi Kudo Hajime Imai Ken Kamata Hiroki Sakamoto Takamitsu Komaki | 2010 | Gastrointestinal Endoscopy2010，，3： | 2 |
| 7 | The MicroRNA-21/PTEN Pathway Regulates the Sensitivity of HER2-Positive Gastric Cancer Cells to Trastuzumab显示文摘 | Kojiro Eto Masaaki Iwatsuki Masayuki Watanabe Satoshi Ida Takatsugu Ishimoto Shiro Iwagami Yoshifumi Baba Yasuo Sakamoto Yuji Miyamoto Naoya Yoshida Hideo Baba | 2014 | Annals of Surgical Oncology2014，，1： | 2 |
| 8 | G-Protein-Coupled Receptor GPR49 is Up-regulated in Basal Cell Carcinoma and Promotes Cell Proliferation and Tumor Formation显示文摘 | Keiji Tanese Mariko Fukuma Taketo Yamada Taisuke Mori Tsutomu Yoshikawa Wakako Watanabe Akira Ishiko Masayuki Amagai Takeji Nishikawa Michiie Sakamoto | 2008 | The American Journal of Pathology2008，，： | 1 |
| 9 | A crop phenology detection method using time-series MODIS data显示文摘 | Toshihiro Sakamoto Masayuki Yokozawa Hitoshi Toritani | 2005 | Remote Sensing of Environment2005，96，： | 1 |
| 10 | Spatio–temporal distribution of rice phenology and cropping systems in the Mekong Delta with special reference to the seasonal water flow of the Mekong and Bassac rivers显示文摘 | Toshihiro Sakamoto Nhan Van Nguyen Hiroyuki Ohno Naoki Ishitsuka Masayuki Yokozawa | 2005 | Remote Sensing of Environment2005，，1： | 1 |
| 11 | Effects of melatonin on the proliferation and cisdiamminedicbloroplatinum (CDDP)sensitivity of cultured huinan ovarian cancer cells 显示文摘 | Masayuki Futagami Shigemi Sato Tomomi Sakamoto | 2001 | CynecolOncol2001，82，3： | 1 |
| 12 | Spatio–temporal distribution of rice phenology and cropping systems in the Mekong Delta with special reference to the seasonal water flow of the Mekong and Bassac rivers显示文摘 | Toshihiro Sakamoto Nhan Van Nguyen Hiroyuki Ohno Naoki Ishitsuka Masayuki Yokozawa | 2005 | Remote Sensing of Environment2005，，1： | 1 |
| 13 | Data mining model using simple and readily available factors could identify patients at high risk for hepatocellular carcinoma in chronic hepatitis C显示文摘 | Masayuki Kurosaki Naoki Hiramatsu Minoru Sakamoto Yoshiyuki Suzuki Manabu Iwasaki Akihiro Tamori Kentaro Matsuura Sei Kakinuma Fuminaka Sugauchi Naoya Sakamoto Mina Nakagawa Namiki Izumi | 2011 | Journal of Hepatology2011，，3： | 1 |
| 14 | Chemotherapy and Targeted Therapy for Patients with Initially Unresectable Colorectal Liver Metastases, Focusing on Conversion Hepatectomy and Long-Term Survival显示文摘 | Toru Beppu Yuji Miyamoto Yasuo Sakamoto Katsunori Imai Hidetoshi Nitta Hiromitsu Hayashi Akira Chikamoto Masayuki Watanabe Takatoshi Ishiko Hideo Baba | 2014 | Annals of Surgical Oncology2014，，3： | 1 |
| 15 | Primary Malignant Melanoma of the Esophagus With Extensive Intraepithelial Extension显示文摘 | Kyoko Inadomi Takatsugu Ishimoto Masayuki Watanabe Masaaki Iwatsuki Kota Arima Satoshi Ida Yohei Nagai Shiro Iwagami Yoshifumi Baba Yasuo Sakamoto Yuji Miyamoto Yumi Honda Ken-ichi Iyama Hideo Baba | 2012 | The Annals of Thoracic Surgery2012，，6： | 1 |
| 16 | A crop phenology detection method using time-series M ODIS data 显示文摘 | Toshihiro Sakamoto Masayuki Yokozawa Hitoshi Toritani | 2005 | Remote Sensing of Environment2005，96，34： | 1 |
| 17 | Base Station Polarization Diversity Reception for Mobile Radio 显示文摘 | SHIGERU KOZONO TOSHINARI TSURUHARA MASAYUKI SAKAMOTO | 1984 | IEEE Transactions on Vehicular Technology (S0018-9545)1984，33，4： | 1 |
| 18 | Treatment of primary malignant melanoma of the esophagus with endoscopic injection of interferon-β combined with systemic chemotherapy: A case report显示文摘 | Hisako Sakamoto Noriya Uedo Hiroyasu Iishi Koji Higashino Ryu Ishihara Kenichirou Mitani Hiroyuki Narahara Masaharu Tatsuta Masayuki Mano Shingo Ishiguro | 2003 | Gastrointestinal Endoscopy2003，，6： | 1 |
| 19 | Endoscopic Ultrasound: Contrast Enhancement显示文摘 | Masayuki Kitano Hiroki Sakamoto Masatoshi Kudo | 2012 | Gastrointestinal Endoscopy Clinics of North Americ2012，，2： | 1 |
| 20 | Estimation of malignant potential of GI stromal tumors by contrast-enhanced harmonic EUS (with videos)显示文摘 | Hiroki Sakamoto Masayuki Kitano Shigenaga Matsui Ken Kamata Takamitsu Komaki Hajime Imai Kensaku Dote Masatoshi Kudo | 2011 | Gastrointestinal Endoscopy2011，，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员